Peptide Skincare & BeautySkin science and ingredient guides

Ingredient or product comparison

TruSkin Vitamin C Face Serum with Hyaluronic Acid & Vitamin E Versus Tree of Life Hyaluronic Acid Serum with Vitamin C | Hydrate + Plump

TruSkin Vitamin C Face Serum with Hyaluronic Acid & Vitamin E Versus Tree of Life Hyaluronic Acid Serum with Vitamin C | Hydrate + Plump Detailed comparison of TruSkin Vitamin C Face Serum with Hyaluronic Acid & Vitamin E versus Tree of Life Hyaluronic Acid Se

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TruSkin Vitamin C Face Serum with Hyaluronic Acid & Vitamin E Versus Tree of Life Hyaluronic Acid Serum with Vitamin C | Hydrate + Plump Detailed comparison of TruSkin Vitamin C Face Serum with Hyaluronic Acid & Vitamin E versus Tree of Life Hyaluronic Acid Serum with Vitamin C | Hydrate + Plump. This brightening serum is formulated around Aloe Barbadensis Leaf Juice and Sodium Ascorbyl Phosphate to brighten dull-looking skin and refine skin texture. This brightening serum is formulated around Sodium Ascorbyl Phosphate to brighten dull-looking skin. Water Aloe Barbadensis Leaf Juice Sodium Ascorbyl Phosphate Dimethyl Sulfone Cassia Angustifolia Seed Polysaccharide Hamamelis Virginiana Water Tocopheryl Acetate Glycerin Arginine Carbomer Centella Asiatica Extract Equisetum Arvense Extract Taraxacum Officinale Extract Pelargonium Graveolens Extract Simmondsia Chinensis Seed Oil Phenoxyethanol Ethylhexylglycerin Sodium Hydroxide Water, Aloe Barbadensis Leaf Juice, Sodium Ascorbyl Phosphate, Dimethyl Sulfone, Cassia Angustifolia Seed Polysaccharide, Hamamelis Virginiana Water, Tocopheryl Acetate, Glycerin, Arginine, Carbomer, Centella Asiatica Extract, Equisetum Arvense Extract, Taraxacum Officinale Extract, Pelargonium Graveolens Extract, Simmondsia Chinensis Seed Oil, Phenoxyethanol, Ethylhexylglycerin, Sodium Hydroxide Aloe Barbadensis Leaf Extract Pelargonium Graveolens Oil Camellia Sinensis Extract Geranium Maculatum Extract Hydroxyethyl Ethylcellulose Carrageenan Sodium Benzoate Potassium Sorbate Water, Hamamelis Virginiana Water, Cassia Angustifolia Seed Polysaccharide, Glycerin, Aloe Barbadensis Leaf Extract, Dimethyl Sulfone, Tocopheryl Acetate, Sodium Ascorbyl Phosphate, Simmondsia Chinensis Seed Oil, Pelargonium Graveolens Oil, Camellia Sinensis Extract, Centella Asiatica Extract, Equisetum Arvense Extract, Taraxacum Officinale Extract, Geranium Maculatum Extract, Hydroxyethyl Ethylcellulose, Carrageenan, Sodium Benzoate, Potassium Sorbate, Ethylhexylglycerin These ingredients are found in both products. Ingredients higher up in an ingredient list are typically present in a larger amount. We don't have a description for Cassia Angustifolia Seed Polysaccharide yet. Centella Asiatica Extract (Centella) is one of the most researched botanical extracts in skincare with decades of studies backing its effects on inflammation, collagen, and the skin barrier. That research keeps pointing back to the same four triterpenoid saponins: Asiaticoside, Madecassoside, Asiatic Acid, and Madecassic Acid. These compounds allow centella to dial back inflammation, encourage the skin to build and hold onto collagen, support the barrier and hydration, and bring solid antioxidant activity to protect against signs of aging. Centella also carries a nice supporting cast of Vitamin A, vitamin C, several B vitamins, and amino acids. Put it all together and you get an ingredient that soothes, hydrates, and protects, all at once. Most of centella's magic comes from the four big compounds (Asiaticoside, Madecassoside, Asiatic Acid, and Madecassic Acid). These are the actives doing the heavy lifting in almost every centella study. Here is the short version of what they do in the skin: So it is not just soothing for the sake of soothing. Centella calms the skin AND helps it rebuild. Just FYI, not all centella on an ingredient list is the same. What you are getting actually depends on the extract: Fun fact on the ratios: the leaves tend to be richest in Madecassoside and Asiaticoside, and lower in the two acids. The exact amounts shift with where the plant is grown and how it is processed. This means purity really does vary brand to brand. Centella is one of the most easygoing actives out there. It layers well with basically everything: niacinamide, hyaluronic acid, peptides, and vitamin C, and also pairs nicely with stronger actives like retinoids and exfoliating acids where it can help take the edge off irritation. On the safety side, centella and its triterpenes are classified as weak sensitizers, meaning allergic reactions are possible but uncommon. Patch tests at 1% and 5% came back negative in test panels, and creams at typical use levels did not cause allergic reactions across large groups of people. But as with any new active, a patch test is still a smart move for very reactive skin. Centella is widely used because it is effective at low percentages. For context, human safety testing found no meaningful irritation from creams containing centella extract at everyday use levels (the tested amounts were well under 1%). The irritancy threshold in animal testing was also above 30% (so real-world formulas sit far below anything concerning). In collagen lab studies, higher concentrations drove more collagen synthesis, so serums built around centella tend to feature it more prominently. Bottom line: you will find centella working nicely anywhere from a fraction of a percent up to hero-ingredient levels depending on whether it is a sup