Peptide Skincare & BeautySkin science and ingredient guides

Ingredient or product comparison

Versed Press Restart Gentle Retinol Serum Versus Paula's Choice Clinical 0.3% Retinol + 2% Bakuchiol Treatment

Versed Press Restart Gentle Retinol Serum Versus Paula's Choice Clinical 0.3% Retinol + 2% Bakuchiol Treatment Detailed comparison of Versed Press Restart Gentle Retinol Serum versus Paula's Choice Clinical 0.3% Retinol + 2% Bakuchiol Treatment. This anti-agin

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Versed Press Restart Gentle Retinol Serum Versus Paula's Choice Clinical 0.3% Retinol + 2% Bakuchiol Treatment Detailed comparison of Versed Press Restart Gentle Retinol Serum versus Paula's Choice Clinical 0.3% Retinol + 2% Bakuchiol Treatment. This anti-aging serum is formulated around Aloe Barbadensis Leaf Juice and Retinol to soften the look of wrinkles and refine skin texture. This anti-aging treatment is formulated around Bakuchiol and Tetrahexyldecyl Ascorbate to soften the look of wrinkles and refine skin texture. Water Helianthus Annuus Seed Oil Aloe Barbadensis Leaf Juice Sodium Acrylate/Sodium Acryloyldimethyl Taurate Copolymer Silica Retinol Tocopherol Tocopheryl Acetate Bakuchiol Crithmum Maritimum Extract Chamomilla Recutita Extract Melia Azadirachta Flower Extract Melia Azadirachta Leaf Extract Paeonia Lactiflora Root Extract Opuntia Streptacantha Stem Extract Lactobacillus/Papaya Fruit Ferment Extract Butyrospermum Parkii Butter Rosa Canina Seed Oil Hippophae Rhamnoides Seed Oil Hydrogenated Vegetable Oil Sodium Hyaluronate Glycerin Lecithin Caprylyl Glycol Caprylic/Capric Triglyceride Xylitol Anhydroxylitol Xylitylglucoside Trehalose Sorbitan Oleate Polysorbate 20 Polysorbate 80 Hexylene Glycol Isohexadecane Phenoxyethanol Ethylhexylglycerin Sorbic Acid Potassium Sorbate Sodium Benzoate Leuconostoc/Radish Root Ferment Filtrate Citric Acid Water, Helianthus Annuus Seed Oil, Aloe Barbadensis Leaf Juice, Sodium Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Silica, Retinol, Tocopherol, Tocopheryl Acetate, Bakuchiol, Crithmum Maritimum Extract, Chamomilla Recutita Extract, Melia Azadirachta Flower Extract, Melia Azadirachta Leaf Extract, Paeonia Lactiflora Root Extract, Opuntia Streptacantha Stem Extract, Lactobacillus/Papaya Fruit Ferment Extract, Butyrospermum Parkii Butter, Rosa Canina Seed Oil, Hippophae Rhamnoides Seed Oil, Hydrogenated Vegetable Oil, Sodium Hyaluronate, Glycerin, Lecithin, Caprylyl Glycol, Caprylic/Capric Triglyceride, Xylitol, Anhydroxylitol, Xylitylglucoside, Trehalose, Sorbitan Oleate, Polysorbate 20, Polysorbate 80, Hexylene Glycol, Isohexadecane, Phenoxyethanol, Ethylhexylglycerin, Sorbic Acid, Potassium Sorbate, Sodium Benzoate, Leuconostoc/Radish Root Ferment Filtrate, Citric Acid Dimethicone Pentaerythrityl Tetraisostearate Isononyl Isononanoate Butylene Glycol Arachidyl Alcohol Glyceryl Polymethacrylate Dimethicone Crosspolymer Behenyl Alcohol PEG-75 Shea Butter Glycerides Glyceryl Stearate C12-15 Alkyl Benzoate Tetrahexyldecyl Ascorbate Ceramide Ng Palmitoyl Tetrapeptide-7 Palmitoyl Hexapeptide-12 Dipotassium Glycyrrhizate Glycyrrhiza Glabra Root Extract Avena Sativa Kernel Extract Arctium Lappa Root Extract Salix Alba Bark Extract Glycine Soja Sterols Allantoin Hydrolyzed Soy Protein Palmitoyl Tripeptide-1 Sodium Hydroxide Tribehenin Dipeptide-2 Polygonum Cuspidatum Root Extract PEG-10 Phytosterol PEG-8 Magnesium Aluminum Silicate Arachidyl Glucoside Chrysin Pentylene Glycol Sodium Acrylates Copolymer Steareth-20 Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer Cetearyl Alcohol Coco-Glucoside Hesperidin Methyl Chalcone N-Hydroxysuccinimide Disodium EDTA Benzoic Acid Water, Dimethicone, Pentaerythrityl Tetraisostearate, Isononyl Isononanoate, Butylene Glycol, Bakuchiol, Arachidyl Alcohol, Glyceryl Polymethacrylate, Dimethicone Crosspolymer, Behenyl Alcohol, Glycerin, PEG-75 Shea Butter Glycerides, Glyceryl Stearate, C12-15 Alkyl Benzoate, Polysorbate 20, Tetrahexyldecyl Ascorbate, Retinol, Ceramide These ingredients are found in both products. Ingredients higher up in an ingredient list are typically present in a larger amount. Bakuchiol is a plant-derived antioxidant from the seeds of the Psoralea corylifolia plant. It has antimicrobial, emollient, skin conditioning, and antioxidant properties. You'll likely see it called a "retinol replacement" but the two are technically not related. This is because bakuchiol is able to flip many of the same switches in your skin cells to tell them to: 1) produce more collagen (type I, III, and IV) 2) activate the same genes retinoids do Unlike retinoids, this ingredient will not increase photosensitivity and is safe to use during pregnancy (but please still check in with your doctor!). The flagship clinical trial from Dhaliwal et al. 2019 found 0.5% bakuchiol (twice daily) and 0.5% retinol (once daily) reduced wrinkles and hyperpigmentation equally, but bakuchiol had significantly less irritation. Systematic reviews also back this up: Bakuchiol is comparable to retinol for photoaging but with better tolerability. It also has mild antibacterial properties against Cutibacterium acnes and antifungal activity in vitro against Candida and dermatophytes. The reason bakuchiol works well is due to its structure; it is a meroterpene phenol, or a hybrid molecule. The phenol half acts as an antioxidant while the terpene half is fat-loving. This helps the molecule slip through the skin barrier. This ingredient is usually used between 0.5-2%. Only one case of contact dermatitis has ever been reported for this ingredient. Caprylyl Glycol is a humectant, skin conditioner, emollient, and preservative booster derived from either caprylic acid or synthetically created. Typical use levels vary from 0.3-1% as a preservative booster and go up to 2% to condition skin. Because it is not a free-fatty acid, this ingredient is fungal acne safe (there's nothing for Malassezia to feed on). Ethylhexylglycerin is created from glycerin. It is a multitasker ingredient that: The CIR Expert Panel found minimal skin absorption or sensitization of any kind in a safety assessment. Though this ingredient is considered well-tolerated, a small number of cases of allergic dermatitis have been published since 2002. Just be sure to patch test if you are unsure. Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations. Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum. Topically, glycerin does several things at once: Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3. Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin. This ingredient is non-irritating, plays well with