Peptide Skincare & BeautySkin science and ingredient guides

Ingredient or product comparison

Vibriance Super C Penetrating Serum Versus Paula's Choice 25% Vitamin C + Glutathione Clinical Serum

Vibriance Super C Penetrating Serum Versus Paula's Choice 25% Vitamin C + Glutathione Clinical Serum Detailed comparison of Vibriance Super C Penetrating Serum versus Paula's Choice 25% Vitamin C + Glutathione Clinical Serum. This brightening serum is formulat

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Vibriance Super C Penetrating Serum Versus Paula's Choice 25% Vitamin C + Glutathione Clinical Serum Detailed comparison of Vibriance Super C Penetrating Serum versus Paula's Choice 25% Vitamin C + Glutathione Clinical Serum. This brightening serum is formulated around 3-O-Ethyl Ascorbic Acid and Hexylresorcinol to brighten dull-looking skin and fade the look of dark spots. This brightening serum is formulated around Tetrahexyldecyl Ascorbate and Ascorbyl Glucoside to brighten dull-looking skin and fade the look of dark spots. Citrus Limon Fruit Water Butylene Glycol Cyclopentasiloxane Dimethicone PEG-8 Isododecane Water Polysilicone-11 3-O-Ethyl Ascorbic Acid Sodium Hyaluronate Glucomannan Citrus Aurantium Dulcis Peel Oil Hexylresorcinol Acetyl Glucosamine Allantoin Panthenol Tocopheryl Acetate Caffeine Decyl Glucoside Coco-Caprylate/Caprate Polyacrylate-13 Polyisobutene Polysorbate 20 Phenoxyethanol Ethylhexylglycerin Ethylhexyl Palmitate Trihydroxystearin Acrylates/C10-30 Alkyl Acrylate Crosspolymer PPG-12/Smdi Copolymer Disodium EDTA Triethanolamine Citrus Limon Fruit Water, Butylene Glycol, Cyclopentasiloxane, Dimethicone, PEG-8, Isododecane, Water, Polysilicone-11, 3-O-Ethyl Ascorbic Acid, Sodium Hyaluronate, Glucomannan, Citrus Aurantium Dulcis Peel Oil, Hexylresorcinol, Acetyl Glucosamine, Allantoin, Panthenol, Tocopheryl Acetate, Caffeine, Decyl Glucoside, Coco-Caprylate/Caprate, Polyacrylate-13, Polyisobutene, Polysorbate 20, Phenoxyethanol, Ethylhexylglycerin, Ethylhexyl Palmitate, Trihydroxystearin, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, PPG-12/Smdi Copolymer, Disodium EDTA, Triethanolamine Tetrahexyldecyl Ascorbate Glycerin C9-12 Alkane Ascorbyl Glucoside Silica Pyrus Malus Fruit Extract Hydrogenated Lecithin Polyglyceryl-6 Polyricinoleate Xanthan Gum Oryza Sativa Bran Extract Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer Cetyl Alcohol Caprylyl Glycol Lysine Carboxymethyl Cysteinate Tocopherol Glutathione Sodium Citrate Sodium Phytate Hexylene Glycol Helianthus Annuus Seed Extract Urea Mannitol Caprylic/Capric Triglyceride Sodium PCA Rosmarinus Officinalis Leaf Extract Polysorbate 60 Sorbitan Isostearate Trehalose Ascorbic Acid Glucose Vanilla Planifolia Fruit Extract Polyquaternium-51 Ergothioneine Triacetin Water, Tetrahexyldecyl Ascorbate, Dimethicone, Glycerin, C9-12 Alkane, Ascorbyl Glucoside, Silica, Pyrus Malus Fruit Extract, Hydrogenated Lecithin, Polyglyceryl-6 Polyricinoleate, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Xanthan Gum, Oryza Sativa Bran Extract, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Cetyl Alcohol, Caprylyl Glycol, Lysine Carboxymethyl Cysteinate, Coco-Caprylate/Caprate, Tocopherol, Glutathione, Sodium Citrate, Sodium Phytate, Hexylene Glycol, Ethylhexylglycerin, Helianthus Annuus Seed Extract, Urea, Mannitol, Caprylic/Capric Triglyceride, Sodium PCA, Rosmarinus Officinalis Leaf Extract, Polysorbate 60, Sorbitan Isostearate, Trehalose, Ascorbic Acid, Glucose, Vanilla Planifolia Fruit Extract, Polyquaternium-51, Ergothioneine, Triacetin, Sodium Hyaluronate, Phenoxyethanol Be the first to review These ingredients are found in both products. Ingredients higher up in an ingredient list are typically present in a larger amount. Acrylates/C10-30 Alkyl Acrylate Crosspolymer is a synthetic polymer. It is used to thicken, emulsify, and improve the texture of products. As an emulsifier, it helps stabilize oil-in-water emulsions to give products an elegant feel when applied. It can also form a thin protective film on skin. One study found that a formula using this polymer helped slow down how quickly other ingredients (like DEET) were absorbed through skin. A 2024 study of over 1,300 patients confirmed that sensitization to this ingredient is rare. It is also non-mutagenic and has a clean track record. Coco-Caprylate/Caprate is a lightweight ester created from coconut oil fatty acids, caprylic acid, and capric acid. It is an emollient that helps soften skin and reduce transepidermal water loss (TEWL). What sets it apart from heavier emollients is its ultralight, non-greasy feel. Once applied, this ingredient dries down quickly and leaves a dry, silky finish behind. This also helps improve spreadability and texture. This ingredient has an excellent safety-record and is non-irritating. Typical concentrations for cosmetics range from 0.5-62%. Research on Malassezia growth found no growth on fatty acid esters with chain lengths shorter than 12 carbons (it prefers C11-24). Since Coco-Caprylate/Caprate is built on C8 and C10 fatty acids, it is out of the range that Malassezia metabolizes, and therefore safe for fungal acne. Dimethicone is a type of synthetic silicone created from natural materials such as quartz. It is also known as polydimethylsiloxane. What it does: Dimethicone comes in different viscosities: Depending on the viscosity, dimethicone has different properties. Ingredients lists don't always show which type is used, so we recommend reaching out to the brand if you have questions about the viscosity. This ingredient is unlikely to cause irritation because it does not get absorbed into skin. However, people with silicone allergies should be careful about using this ingredient. Note: Dimethicone may contribute to pilling. This is because it is not oil or water soluble, so pilling may occur when layered with products. When mixed with heavy oils in a formula, the outcome is also quite greasy. Ethylhexylglycerin is created from glycerin. It is a multitasker ingredient that: The CIR Expert Panel found minimal skin absorption or sensitization of any kind in a safety assessment. Though this ingredient is considered well-tolerated, a small number of cases of allergic dermatitis have been published since 2002. Just be sure to patch test if you are unsure. Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations. Phenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!). It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while onl