Peptide Skincare & BeautySkin science and ingredient guides

Ingredient or product comparison

Youth To The People Polypeptide-121 Future Cream with Peptides and Ceramides Versus Estée Lauder Revitalizing Supreme + Night

Youth To The People Polypeptide-121 Future Cream with Peptides and Ceramides Versus Estée Lauder Revitalizing Supreme + Night Detailed comparison of Youth To The People Polypeptide-121 Future Cream with Peptides and Ceramides versus Estée Lauder Revitalizing S

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Youth To The People Polypeptide-121 Future Cream with Peptides and Ceramides Versus Estée Lauder Revitalizing Supreme + Night Detailed comparison of Youth To The People Polypeptide-121 Future Cream with Peptides and Ceramides versus Estée Lauder Revitalizing Supreme + Night. This anti-aging moisturizer is formulated around Hydrolyzed Hyaluronic Acid and Acetyl Tetrapeptide-9 to soften the look of wrinkles and hydrate skin. This anti-aging night moisturizer is formulated around Niacinamide and Moringa Oleifera Seed Extract to soften the look of wrinkles and hydrate skin. Water Dicaprylyl Carbonate Hydrolyzed Hyaluronic Acid Trimethylolpropane Tricaprylate/Tricaprate Tridecyl Trimellitate Propanediol Sh-Polypeptide-121 Polyglyceryl-3 Methylglucose Distearate Panthenol Niacinamide Proline Tocopheryl Acetate Aloe Barbadensis Leaf Juice Hydrolyzed Cannabis Sativa Seed Extract Hydrolyzed Rice Protein Hydrolyzed Pea Protein Salvia Hispanica Seed Extract Acetyl Tetrapeptide-11 Acetyl Tetrapeptide-9 Acetyl Tetrapeptide-2 Hibiscus Sabdariffa Fruit Extract Ammonium Acryloyldimethyltaurate/Beheneth-25 Methacrylate Crosspolymer Hydrolyzed Linseed Seed Castor Oil/Ipdi Copolymer Ceramide AP Ceramide NP Cetearyl Alcohol Cetearyl Glucoside Glycerin Hydrolyzed Sodium Hyaluronate Coco-Caprylate/Caprate Dilinoleic Acid Benzyl Alcohol Zingiber Officinale Root Extract Bisabolol Caprylyl Glycol Carbomer Dimethyl Isosorbide Dipropylene Glycol Erythritol Ethylhexylglycerin Glucose 1,2-Hexanediol Trisodium Ethylenediamine Disuccinate Glyceryl Stearate Phytosphingosine Polyacrylate Crosspolymer-6 Polysorbate 20 Caprylhydroxamic Acid Potassium Sorbate Glycine Hydroxyacetophenone Sodium Benzoate T-Butyl Alcohol Citric Acid Sodium Citrate Sodium Lactate Triheptanoin Xanthan Gum Water, Dicaprylyl Carbonate, Hydrolyzed Hyaluronic Acid, Trimethylolpropane Tricaprylate/Tricaprate, Tridecyl Trimellitate, Propanediol, Sh-Polypeptide-121, Polyglyceryl-3 Methylglucose Distearate, Panthenol, Niacinamide, Proline, Tocopheryl Acetate, Aloe Barbadensis Leaf Juice, Hydrolyzed Cannabis Sativa Seed Extract, Hydrolyzed Rice Protein, Hydrolyzed Pea Protein, Salvia Hispanica Seed Extract, Acetyl Tetrapeptide-11, Acetyl Tetrapeptide-9, Acetyl Tetrapeptide-2, Hibiscus Sabdariffa Fruit Extract, Ammonium Acryloyldimethyltaurate/Beheneth-25 Methacrylate Crosspolymer, Hydrolyzed Linseed Seed, Castor Oil/Ipdi Copolymer, Ceramide AP, Ceramide NP, Cetearyl Alcohol, Cetearyl Glucoside, Glycerin, Hydrolyzed Sodium Hyaluronate, Coco-Caprylate/Caprate, Dilinoleic Acid, Benzyl Alcohol, Zingiber Officinale Root Extract, Bisabolol, Caprylyl Glycol, Carbomer, Dimethyl Isosorbide, Dipropylene Glycol, Erythritol, Ethylhexylglycerin, Glucose, 1,2-Hexanediol, Trisodium Ethylenediamine Disuccinate, Glyceryl Stearate, Phytosphingosine, Polyacrylate Crosspolymer-6, Polysorbate 20, Caprylhydroxamic Acid, Potassium Sorbate, Glycine, Hydroxyacetophenone, Sodium Benzoate, T-Butyl Alcohol, Citric Acid, Sodium Citrate, Sodium Lactate, Triheptanoin, Xanthan Gum Glycine Soja Oil Caprylic/Capric/Myristic/Stearic Triglyceride Prunus Amygdalus Dulcis Oil Dimethicone Stearyl Alcohol Butylene Glycol Steareth-2 Cocos Nucifera Oil Vitis Vinifera Seed Oil Steareth-21 Moringa Oleifera Seed Extract Limonium Vulgare Flower/Leaf/Stem Extract Sodium Hyaluronate Acetyl Hexapeptide-8 Laminaria Digitata Extract Whey Protein Acetyl Glucosamine Opuntia Tuna Fruit Extract Citrullus Lanatus Fruit Extract Persea Gratissima Oil Mangifera Indica Seed Oil Aminopropyl Ascorbyl Phosphate Algae Extract Caffeine Cucum These ingredients are found in both products. Ingredients higher up in an ingredient list are typically present in a larger amount. Caprylyl Glycol is a humectant, skin conditioner, emollient, and preservative booster derived from either caprylic acid or synthetically created. Typical use levels vary from 0.3-1% as a preservative booster and go up to 2% to condition skin. Because it is not a free-fatty acid, this ingredient is fungal acne safe (there's nothing for Malassezia to feed on). Carbomer is a synthetic thickening and gelling agent. It's basically the ingredient that gives a lot of serums, gels, creams, and sunscreens their smooth, non-sticky texture. Although legally permitted at very high levels, carbomers are normally used at concentrations below 1%. It also needs to be neutralized to actually thicken, and because it is a large molecule, it doesn't really penetrate the skin barrier. Allergy-wise, the risk is very low. Clinical studies show carbomers have low potential for skin irritation/sensitization even at concentrations up to 100%. A 2024 UK study patch-tested 1,302 patients and found true allergy to the parent group of carbomer to be rare with no confirmed relevant reactions. Citric Acid is an alpha hydroxy acid (AHA) naturally found in citrus fruits like oranges, lemons, and limes. Like other AHAs, citric acid can exfoliate skin by breaking down the bonds that hold dead skin cells together. This helps reveal smoother and brighter skin underneath. However, this exfoliating effect only happens at high concentrations (20%) which can be hard to find in cosmetic products. Due to this, citric acid is usually included in small amounts as a pH adjuster. This helps keep products slightly more acidic and compatible with skin's natural pH. In skincare formulas, citric acid can: While it can provide some skin benefits, research shows lactic acid and glycolic acid are generally more effective and less irritating exfoliants. Most citric acid used in skincare today is made by fermenting sugars (usually from molasses). This synthetic version is identical to the natural citrus form but easier to stabilize and use in formulations. Rosacea skin has a lower threshold for acids generally, with 62.5% of rosacea subjects in one study reacting to lactic acid in a sting test. This is why we mark citric acid as a potential rosacea trigger. However, this ingredient shows up as a pH adjuster or chelator at roughly 0.1-1% in many products. These low levels are unlikely to be an issue for rosacea skin and becomes a potential trigger at exfoliating concentrations (20%). Because everybody's skin is unique, we recommend a patch test if you are unsure. Glucose is a simple sugar (a monosaccharide). In skincare, it is mostly a humectant and skin conditioning agent. Mechanistically, it has multiple hydroxyl groups that hydrogen-bond to water. This pulls moisture into the upper layers of skin to keep the surface soft and hydrated. It's worth knowing sugars are alread