Peptide Skincare & BeautySkin science and ingredient guides

Ingredient or product comparison

ZO Skin Health Brightalive® Versus Paula's Choice 1% Retinol Treatment

ZO Skin Health Brightalive® Versus Paula's Choice 1% Retinol Treatment Detailed comparison of ZO Skin Health Brightalive® versus Paula's Choice 1% Retinol Treatment US. This brightening serum is formulated around Niacinamide and Aminopropyl Ascorbyl Phosphate

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ZO Skin Health Brightalive® Versus Paula's Choice 1% Retinol Treatment Detailed comparison of ZO Skin Health Brightalive® versus Paula's Choice 1% Retinol Treatment US. This brightening serum is formulated around Niacinamide and Aminopropyl Ascorbyl Phosphate to brighten dull-looking skin and fade the look of dark spots. This anti-aging treatment is formulated around Retinol and Tetrahexyldecyl Ascorbate to soften the look of wrinkles and refine skin texture. Water Glycerin Dimethicone Niacinamide Caprylyl Methicone C12-15 Alkyl Benzoate Glyceryl Stearate PEG-100 Stearate Acrylamide/Ammonium Acrylate Copolymer Aminopropyl Ascorbyl Phosphate Cetyl Alcohol PEG-12 Dimethicone/PPG-20 Crosspolymer Tranexamic Acid Acetyl Glucosamine Dipotassium Glycyrrhizate Diglucosyl Gallic Acid Beta-Glucan Papain Lactic Acid/Glycolic Acid Copolymer Palmitoyl Sh-Octapeptide-24 Amide Palmitoyl Sh-Tripeptide-5 Norisoleucyl Sh-Nonapeptide-1 Elaeis Guineensis Oil Gossypium Herbaceum Seed Oil Linum Usitatissimum Seed Oil Bidens Pilosa Extract Tocopherol Sodium Bisulfite Tocopheryl Acetate Ascorbic Acid Retinyl Palmitate Xanthan Gum Polyisobutene Polymethyl Methacrylate Polyvinyl Alcohol Polysorbate 20 Disodium EDTA 1,2-Hexanediol Carbomer Algin Sodium Hydroxide Parfum Phenoxyethanol Caprylyl Glycol Chlorphenesin Pentylene Glycol Water, Glycerin, Dimethicone, Niacinamide, Caprylyl Methicone, C12-15 Alkyl Benzoate, Glyceryl Stearate, PEG-100 Stearate, Acrylamide/Ammonium Acrylate Copolymer, Aminopropyl Ascorbyl Phosphate, Cetyl Alcohol, PEG-12 Dimethicone/PPG-20 Crosspolymer, Tranexamic Acid, Acetyl Glucosamine, Dipotassium Glycyrrhizate, Diglucosyl Gallic Acid, Beta-Glucan, Papain, Lactic Acid/Glycolic Acid Copolymer, Palmitoyl Sh-Octapeptide-24 Amide, Palmitoyl Sh-Tripeptide-5 Norisoleucyl Sh-Nonapeptide-1, Elaeis Guineensis Oil, Gossypium Herbaceum Seed Oil, Linum Usitatissimum Seed Oil, Bidens Pilosa Extract, Tocopherol, Sodium Bisulfite, Tocopheryl Acetate, Ascorbic Acid, Retinyl Palmitate, Xanthan Gum, Polyisobutene, Polymethyl Methacrylate, Polyvinyl Alcohol, Polysorbate 20, Disodium EDTA, 1,2-Hexanediol, Carbomer, Algin, Sodium Hydroxide, Parfum, Phenoxyethanol, Caprylyl Glycol, Chlorphenesin, Pentylene Glycol Butylene Glycol Isononyl Isononanoate Castor Isostearate Succinate Dimethicone Crosspolymer PEG-33 Behenyl Alcohol Pentaerythrityl Tetraisostearate Polymethylsilsesquioxane Tetrahexyldecyl Ascorbate Retinol Ceramide Ng Palmitoyl Tetrapeptide-7 Palmitoyl Hexapeptide-12 Sodium Hyaluronate Glycyrrhiza Glabra Root Extract Avena Sativa Kernel Extract Arctium Lappa Seed Oil Salix Alba Extract Glycine Soja Sterols Lecithin Allantoin Hydrolyzed Soy Protein Sorbitan Laurate Acetyl Dipeptide-1 Cetyl Ester Hydroxyethylcellulose Palmitoyl Tripeptide-1 Tribehenin Ethylhexylglycerin PEG-75 Shea Butter Glycerides PPG-12/Smdi Copolymer PEG-10 Phytosterol PEG-8 Dimethicone PEG-14 Magnesium Aluminum Silicate Arachidyl Glucoside Arachidyl Alcohol Sclerotium Gum Benzoic Acid Water, Dimethicone, Glycerin, Butylene Glycol, Isononyl Isononanoate, Castor Isostearate Succinate, Glyceryl Stearate, C12-15 Alkyl Benzoate, Dimethicone Crosspolymer, PEG-33, Polysorbate 20, Behenyl Alcohol, PEG-100 Stearate, Pentaerythrityl Tetraisostearate, Polymethylsilsesquioxane, Tetrahexyldecyl Ascorbate, Retinol, Ceramide Ng, Palmitoyl Tetrapeptide-7, Palmitoyl Hexapeptide-12, Sodium Hyaluronate, Dipotassium Glycyrrhizate, Glycyrrhiza Glabra Root Extract, Be the first to review These ingredients are found in both products. Ingredients higher up in an ingredient list are typically present in a larger amount. C12-15 Alkyl Benzoate is a lightweight emollient made by combinig benzoic acid with fatty alcohols that are 12-15 carbons long. In cosmetics, it plays several roles: The Cosmetic Review Expert Panel has concluded the alkyl benzoate group to be safe as used in cosmetics; it wasn't found to be a skin irritant and unlikely to be absorbed due to its low water solubility. This report recorded almost 1000 reported uses with concentrations up to 59% in leave-on products but your cosmetics will typically use 0.5-15% depending on the product. It's often called a "SPF booster": this is because it keeps UV filters properly dissolved and evenly distributed to support a sunscreen's performance. It doesn't actually raise SPF on its own. Overall, this ingredient is well tolerated. This ingredient is fungal acne safe because it is an ester of benzoic acid. Think of this ingredient as two parts stuck together: an oily part and an acid part. Malassezia only gets a meal when it can snip off a fatty acid to eat. With C12-15 Alkyl Benzoate, the acid part is benzoic acid, which isn't a fatty acid and which the yeast can't use as food. Benzoic acid is actually used as a preservative to stop yeast from growing. The oily part is a blend of C12-15 fatty alcohols but fatty alcohols in this size range can support only a little Malassezia growth (mostly for one species of Malassezia as well). In the ingredient, those alcohols stay locked inside the molecule. The yeast can only reach them by snipping the benzoate bond, and that type of bond is harder for it to cut than a normal fatty bond. So not much gets released. And whatever does get snipped comes packaged with benzoic acid, which discourages yeast growth. Caprylyl Glycol is a humectant, skin conditioner, emollient, and preservative booster derived from either caprylic acid or synthetically created. Typical use levels vary from 0.3-1% as a preservative booster and go up to 2% to condition skin. Because it is not a free-fatty acid, this ingredient is fungal acne safe (there's nothing for Malassezia to feed on). Carbomer is a synthetic thickening and gelling agent. It's basically the ingredient that gives a lot of serums, gels, creams, and sunscreens their smooth, non-sticky texture. Although legally permitted at very high levels, carbomers are normally used at concentrations below 1%. It also needs to be neutralized to actually thicken, and because it is a large molecule, it doesn't really penetrate the skin barrier. Allergy-wise, the risk is very low. Clinical studies show carbomers have low potential for skin irritation/sensitization even at concentrations up to 100%. A 2024 UK study patch-tested 1,302 patients and found true allergy to the parent group of carbomer to be rare with no confirmed relevant reactions. Dimethicone is a type of synthetic silicone created from natural materials such