Peptide Skincare & BeautySkin science and ingredient guides

Ingredient or product comparison

ZO Skin Health Daily Power Defense Versus Medik8 Liquid Peptides

ZO Skin Health Daily Power Defense Versus Medik8 Liquid Peptides Detailed comparison of ZO Skin Health Daily Power Defense versus Medik8 Liquid Peptides. This barrier-repair moisturizer is formulated around Laminaria Digitata Extract and Beta-Glucan to strengt

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ZO Skin Health Daily Power Defense Versus Medik8 Liquid Peptides Detailed comparison of ZO Skin Health Daily Power Defense versus Medik8 Liquid Peptides. This barrier-repair moisturizer is formulated around Laminaria Digitata Extract and Beta-Glucan to strengthen the skin barrier and hydrate skin. This anti-aging serum is formulated around Carnosine and Palmitoyl Tripeptide-5 to soften the look of wrinkles and refine skin texture. Water Dicaprylyl Carbonate Cetearyl Isononanoate Glycerin Pentylene Glycol Cetearyl Alcohol Steareth-20 Safflower Oil/Palm Oil Aminopropanediol Esters Laminaria Digitata Extract Opuntia Ficus-Indica Stem Extract Arabidopsis Thaliana Extract Marrubium Vulgare Meristem Cell Culture Leontopodium Alpinum Meristem Cell Culture Retinyl Palmitate Tocopheryl Acetate Tocopherol Micrococcus Lysate Caprylyl Glycol Hexylene Glycol Lactose Galactoarabinan Lecithin Schizophyllan Beta-Glucan 1,2-Hexanediol Carbomer Cellulose Maltodextrin C14-22 Alcohols Cetearyl Glucoside C12-20 Alkyl Glucoside Hydroxypropyl Methylcellulose Disodium EDTA Sodium Hydroxide Phenoxyethanol Ethylhexylglycerin Sodium Benzoate Parfum CI 77007 Limonene Water, Dicaprylyl Carbonate, Cetearyl Isononanoate, Glycerin, Pentylene Glycol, Cetearyl Alcohol, Steareth-20, Safflower Oil/Palm Oil Aminopropanediol Esters, Laminaria Digitata Extract, Opuntia Ficus-Indica Stem Extract, Arabidopsis Thaliana Extract, Marrubium Vulgare Meristem Cell Culture, Leontopodium Alpinum Meristem Cell Culture, Retinyl Palmitate, Tocopheryl Acetate, Tocopherol, Micrococcus Lysate, Caprylyl Glycol, Hexylene Glycol, Lactose, Galactoarabinan, Lecithin, Schizophyllan, Beta-Glucan, 1,2-Hexanediol, Carbomer, Cellulose, Maltodextrin, C14-22 Alcohols, Cetearyl Glucoside, C12-20 Alkyl Glucoside, Hydroxypropyl Methylcellulose, Disodium EDTA, Sodium Hydroxide, Phenoxyethanol, Ethylhexylglycerin, Sodium Benzoate, Parfum, CI 77007, Limonene Butylene Glycol Inulin Sodium Hyaluronate Panthenol Alpha-Glucan Oligosaccharide Carnosine Polysorbate 20 Hydroxypropyl Cyclodextrin Dunaliella Salina Extract Citric Acid Palmitoyl Tripeptide-5 Acetyl Hexapeptide-8 Tetrapeptide-21 Pentapeptide-18 Palmitoyl Tripeptide-1 Pantolactone Palmitoyl Tripeptide-38 Palmitoyl Tetrapeptide-7 Glyceryl Caprylate Lactic Acid/Glycolic Acid Copolymer Polyvinyl Alcohol Phenylpropanol Copper Palmitoyl Heptapeptide-14 Heptapeptide-15 Palmitate Potassium Sorbate Xanthan Gum Water, Glycerin, Butylene Glycol, Inulin, Sodium Hyaluronate, Panthenol, Alpha-Glucan Oligosaccharide, Carnosine, Carbomer, Polysorbate 20, Caprylyl Glycol, Phenoxyethanol, Hydroxypropyl Cyclodextrin, Dunaliella Salina Extract, Ethylhexylglycerin, Citric Acid, Palmitoyl Tripeptide-5, Sodium Benzoate, Acetyl Hexapeptide-8, Tetrapeptide-21, Pentapeptide-18, Palmitoyl Tripeptide-1, Pantolactone, Palmitoyl Tripeptide-38, Palmitoyl Tetrapeptide-7, Glyceryl Caprylate, Lactic Acid/Glycolic Acid Copolymer, Polyvinyl Alcohol, Phenylpropanol, Copper Palmitoyl Heptapeptide-14, Heptapeptide-15 Palmitate, Potassium Sorbate, Xanthan Gum These ingredients are found in both products. Ingredients higher up in an ingredient list are typically present in a larger amount. Caprylyl Glycol is a humectant, skin conditioner, emollient, and preservative booster derived from either caprylic acid or synthetically created. Typical use levels vary from 0.3-1% as a preservative booster and go up to 2% to condition skin. Because it is not a free-fatty acid, this ingredient is fungal acne safe (there's nothing for Malassezia to feed on). Carbomer is a synthetic thickening and gelling agent. It's basically the ingredient that gives a lot of serums, gels, creams, and sunscreens their smooth, non-sticky texture. Although legally permitted at very high levels, carbomers are normally used at concentrations below 1%. It also needs to be neutralized to actually thicken, and because it is a large molecule, it doesn't really penetrate the skin barrier. Allergy-wise, the risk is very low. Clinical studies show carbomers have low potential for skin irritation/sensitization even at concentrations up to 100%. A 2024 UK study patch-tested 1,302 patients and found true allergy to the parent group of carbomer to be rare with no confirmed relevant reactions. Ethylhexylglycerin is created from glycerin. It is a multitasker ingredient that: The CIR Expert Panel found minimal skin absorption or sensitization of any kind in a safety assessment. Though this ingredient is considered well-tolerated, a small number of cases of allergic dermatitis have been published since 2002. Just be sure to patch test if you are unsure. Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations. Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum. Topically, glycerin does several things at once: Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3. Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin. This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products. Just know very high concentrations (>40%) can feel tacky in low humidity. Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine. Phenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!). It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome. On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions