Peptide Skincare & BeautySkin science and ingredient guides

Product and ingredient reference

Anai Rui Vitamin C + Glutathione Serum

Anai Rui Vitamin C + Glutathione Serum Ingredients in Anai Rui Vitamin C + Glutathione Serum explained: benefits, concerns, and detailed analysis of 22 ingredients including Water, Glutathione, and 3-O-Ethyl Ascorbic Acid A serum with 22 ingredients, including

Anai Rui Vitamin C + Glutathione Serum Ingredients in Anai Rui Vitamin C + Glutathione Serum explained: benefits, concerns, and detailed analysis of 22 ingredients including Water, Glutathione, and 3-O-Ethyl Ascorbic Acid A serum with 22 ingredients, including vitamin C, niacinamide, and hyaluronic acid. This brightening serum is formulated around Glutathione and 3-O-Ethyl Ascorbic Acid to brighten dull-looking skin and fade the look of dark spots. We independently verify ingredients, backed by peer-reviewed research. Suggest an update. Water Glutathione 3-O-Ethyl Ascorbic Acid Niacinamide Glycerin Sodium Polyglutamate Sodium Hyaluronate Hydrolyzed Sodium Hyaluronate Carbomer Butylene Glycol Betaine Panthenol Arginine Beta-Glucan Portulaca Oleracea Extract Aloe Barbadensis Leaf Juice Polyglycerin-10 Rosa Hybrid Flower Extract Gardenia Florida Fruit Extract Phellodendron Amurense Bark Extract 1,2-Hexanediol Pentylene Glycol Water, Glutathione, 3-O-Ethyl Ascorbic Acid, Niacinamide, Glycerin, Sodium Polyglutamate, Sodium Hyaluronate, Hydrolyzed Sodium Hyaluronate, Carbomer, Butylene Glycol, Betaine, Panthenol, Arginine, Beta-Glucan, Portulaca Oleracea Extract, Aloe Barbadensis Leaf Juice, Polyglycerin-10, Rosa Hybrid Flower Extract, Gardenia Florida Fruit Extract, Phellodendron Amurense Bark Extract, 1,2-Hexanediol, Pentylene Glycol Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product. So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation. You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated! Glutathione is a tiny protein-like molecule (a "tripeptide" build from 3 amino acids: glycine, cysteine, and glutamic acid) that your body already makes on its own. Inside your body, it acts as one of the skin's main antioxidants that help fight against free radicals. In skincare, it's best known as a brightening ingredient that slows down tyrosinase, the key enzyme that makes skin pigment. It also nudges the skin toward making a lighter type of pigment instead of a darker one. This is why you'll see it in products aimed at dark spots and uneven tone. A small number of real human trials have found a topical glutathione lotion: The honest caveat is that the current evidence is still thin (few studies, small groups, short timelines). Glutathione also doesn't absorb into skin very easily so results tend to be modest and fade if you stop using it. One thing worth clearing up: The scary side effects you may have heard about come from glutathione injected intravenously, which has real safety concerns. Applying it topically is a completely different thing and has a clean track record. Most human studies used it around 2% (as Glutathione or Glutathione Disulfide) and a 2% oxidized glutathione lotion and a 2% S-acyl glutathione cream are the concentrations with actual clinical data behind them. There's no established "ideal" percentage yet but 1-2% is the evidence-backed range. Allergy-wise, there is very low risk for this ingredient; it was well-tolerated across the topical trials. Only one participant had mild temporary redness that cleared up on its own and another study reported no adverse reactions at all. One trial had ~10% of users drop out for irritation was using a combination cream that also had 10% azelaic acid so the irritation likely wasn't from the glutathione. There's no notable contact-allergy signal for topical glutathione in the literature but patch-testing before first use is still sensible for those with sensitive skin. 3-O-Ethyl Ascorbic Acid is one of the most popular "stable" vitamin C derivatives in skincare. Plain ascorbic acid is fantastic but notoriously fragile; it browns, oxidizes, and loses potency fast. So attaching an ethyl group to the third carbon of the molecule gives it some cool perks: In a formula, it does the 3 classic vitamin C jobs: it acts as an antioxidant, helps brighten skin tone by inhibiting tyrosinase, and supports collagen. The evidence is reasonably solid for a cosmetic ingredient; Liao and colleagues (2018) showed it's significantly more stable than ascorbic acid while st No written reviews yet. Be the first to review this product. Search reviews by skin type, ingredient, or keyword. Anai Rui is a Hong Kongese brand We're dedicated to providing you with the most up-to-date and science-backed ingredient info out there. The data we've presented on this page has been verified by a member of the SkinSort Team. · Updated March 24, 2026 • Added by crysv2797

Open original product source