Depology Matriplex Peptide Intense Cream

Depology Matriplex Peptide Intense Cream Ingredients in Depology Matriplex Peptide Intense Cream explained: benefits, concerns, and detailed analysis of 40 ingredients including Centella Asiatica Extract, Butylene Glycol, and Glycerin A moisturizer with 40 ingredients, including niacinamide, hyaluronic acid, and peptides. This anti-aging moisturizer is formulated around Centella Asiatica Extract and Niacinamide to soften the look of wrinkles and strengthen the skin barrier. We independently verify ingredients, backed by peer-reviewed research. Suggest an update. Centella Asiatica Extract Butylene Glycol Glycerin Water Cyclohexasiloxane Panthenol Sorbitan Olivate Cetearyl Olivate Melaleuca Alternifolia Leaf Extract Niacinamide 1,2-Hexanediol Camellia Sinensis Leaf Extract Stearyl Alcohol Glyceryl Stearate Melia Azadirachta Flower Extract Melia Azadirachta Leaf Extract Houttuynia Cordata Extract Glycine Max Seed Extract Sodium PCA Sodium Polystyrene Sulfonate Sodium Hyaluronate Sorghum Bicolor Stalk Juice Pentylene Glycol Ethylhexylglycerin Adenosine Carbomer Sodium Lactate Hydroxypropyl Cyclodextrin Polysorbate 20 Sodium Benzoate Potassium Sorbate Caprylyl Glycol N-Prolyl Palmitoyl Tripeptide-56 Acetate Palmitoyl Tripeptide-38 Madecassoside Asiaticoside Palmitoyl Tripeptide-1 Palmitoyl Tetrapeptide-7 Asiatic Acid Madecassic Acid Centella Asiatica Extract, Butylene Glycol, Glycerin, Water, Cyclohexasiloxane, Panthenol, Sorbitan Olivate, Cetearyl Olivate, Melaleuca Alternifolia Leaf Extract, Niacinamide, 1,2-Hexanediol, Camellia Sinensis Leaf Extract, Stearyl Alcohol, Glyceryl Stearate, Melia Azadirachta Flower Extract, Melia Azadirachta Leaf Extract, Houttuynia Cordata Extract, Glycine Max Seed Extract, Sodium PCA, Sodium Polystyrene Sulfonate, Sodium Hyaluronate, Sorghum Bicolor Stalk Juice, Pentylene Glycol, Ethylhexylglycerin, Adenosine, Carbomer, Sodium Lactate, Hydroxypropyl Cyclodextrin, Polysorbate 20, Sodium Benzoate, Potassium Sorbate, Caprylyl Glycol, N-Prolyl Palmitoyl Tripeptide-56 Acetate, Palmitoyl Tripeptide-38, Madecassoside, Asiaticoside, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Asiatic Acid, Madecassic Acid Centella Asiatica Extract (Centella) is one of the most researched botanical extracts in skincare with decades of studies backing its effects on inflammation, collagen, and the skin barrier. That research keeps pointing back to the same four triterpenoid saponins: Asiaticoside, Madecassoside, Asiatic Acid, and Madecassic Acid. These compounds allow centella to dial back inflammation, encourage the skin to build and hold onto collagen, support the barrier and hydration, and bring solid antioxidant activity to protect against signs of aging. Centella also carries a nice supporting cast of Vitamin A, vitamin C, several B vitamins, and amino acids. Put it all together and you get an ingredient that soothes, hydrates, and protects, all at once. Most of centella's magic comes from the four big compounds (Asiaticoside, Madecassoside, Asiatic Acid, and Madecassic Acid). These are the actives doing the heavy lifting in almost every centella study. Here is the short version of what they do in the skin: So it is not just soothing for the sake of soothing. Centella calms the skin AND helps it rebuild. Just FYI, not all centella on an ingredient list is the same. What you are getting actually depends on the extract: Fun fact on the ratios: the leaves tend to be richest in Madecassoside and Asiaticoside, and lower in the two acids. The exact amounts shift with where the plant is grown and how it is processed. This means purity really does vary brand to brand. Centella is one of the most easygoing actives out there. It layers well with basically everything: niacinamide, hyaluronic acid, peptides, and vitamin C, and also pairs nicely with stronger actives like retinoids and exfoliating acids where it can help take the edge off irritation. On the safety side, centella and its triterpenes are classified as weak sensitizers, meaning allergic reactions are possible but uncommon. Patch tests at 1% and 5% came back negative in test panels, and creams at typical use levels did not cause allergic reactions across large groups of people. But as with any new active, a patch test is still a smart move for very reactive skin. Centella is widely used because it is effective at low percentages. For context, human safety testing found no meaningful irritation from creams containing centella extract at everyday use levels (the tested amounts were well under 1%). The irritancy threshold in animal testing was also above 30% (so real-world formulas sit far below anything concerning). In collagen lab studies, higher concentrations drove more collagen synthesis, so serums built around centella tend to feature it more prominently. Bottom line: you will find centella working nicely anywhere from a fraction of a percent up to hero-ingredient levels depending on whether it is a supporting soother or the main event. Fun fact: Centella has been used as a medicine and in food for many centuries. As a medicine, it is used to treat burns, scratches, and wounds. Butylene Glycol (or BG) is use No written reviews yet. Be the first to review this product. Search reviews by skin type, ingredient, or keyword. Depology is a Korean brand We're dedicated to providing you with the most up-to-date and science-backed ingredient info out there. The data we've presented on this page has been verified by a member of the SkinSort Team. · Updated November 7, 2024 • Added by sophiesml

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