Peptide Skincare & BeautySkin science and ingredient guides

Product and ingredient reference

Image Skincare Ageless Total Pure Hyaluronic 6 Filler

Image Skincare Ageless Total Pure Hyaluronic 6 Filler Image Skincare Ageless Total Pure Hyaluronic 6 Filler ingredients explained: Aqua, Hyaluronic Acid, Sodium Hyaluronate, Panthenol, Tocopheryl Acetate (Vitamin E), Prunus Armeniaca (Apricot) Kernel Oil Show

Image Skincare Ageless Total Pure Hyaluronic 6 Filler Image Skincare Ageless Total Pure Hyaluronic 6 Filler ingredients explained: Aqua, Hyaluronic Acid, Sodium Hyaluronate, Panthenol, Tocopheryl Acetate (Vitamin E), Prunus Armeniaca (Apricot) Kernel Oil Show all ingredients by function Aqua solvent Hyaluronic Acid skin-identical ingredient, moisturizer/​humectant goodie Sodium Hyaluronate 0, 0 Panthenol soothing, moisturizer/​humectant Tocopheryl Acetate (Vitamin E) antioxidant Prunus Armeniaca (Apricot) Kernel Oil emollient 0, 1-2 Good old water, aka H2O. The most common skincare ingredient of all. You can usually find it right in the very first spot of the ingredient list, meaning it’s the biggest thing out of all the stuff that makes up the product. It’s mainly a solvent for ingredients that do not like to dissolve in oils but rather in water. Expand to read more Once inside the skin, it hydrates, but not from the outside - putting pure water on the skin (hello long baths!) is drying. One more thing: the water used in cosmetics is purified and deionized (it means that almost all of the mineral ions inside it is removed). Like this, the products can stay more stable over time. It’s naturally in our skin and behaves there like a sponge It can bind up to 1000 times its own weight in water It is a big molecule from repeated subunits (polymer) so different molecular weight versions exist (unfortunately there is no way to determine MW from INCI list only) High-molecular-weight-HA (>500 kDa) is an excellent surface hydrator, skin protectant and can act as an osmotic pump helping water-soluble actives to penetrate deeper into the skin Low-molecular-weight-HA (< 500 kDa) can hydrate the skin somewhat deeper though it is still a big molecule and works mainly in the epidermis (outer layer of the skin) Low-molecular-weight-HA might also help the skin to repair itself by increasing its self-defense (~ 200kDa used in the study) Ultra-low-molecular-weight-HA (<50kDa) is a controversial ingredient and might work as a pro-inflammatory signal molecule It’s the - sodium form - cousin of the famous NMF, hyaluronic acid (HA). If HA does not tell you anything we have a super detailed, geeky explanation about it here. The TL; DR version of HA is that it's a huge polymer (big molecule from repeated subunits) found in the skin that acts as a sponge helping the skin to hold onto water, being plump and elastic. HA is famous for its crazy water holding capacity as it can bind up to 1000 times its own weight in water. As far as skincare goes, sodium hyaluronate and hyaluronic acid are pretty much the same and the two names are used interchangeably. As cosmetic chemist kindofstephen writes on reddit "sodium hyaluronate disassociates into hyaluronic acid molecule and a sodium atom in solution". In spite of this, if you search for "hyaluronic acid vs sodium hyaluronate" you will find on multiple places that sodium hyaluronate is smaller and can penetrate the skin better. Chemically, this is definitely not true, as the two forms are almost the same, both are polymers and the subunits can be repeated in both forms as much as you like. (We also checked Prospector for sodium hyaluronate versions actually used in cosmetic products and found that the most common molecular weight was 1.5-1.8 million Da that absolutely counts as high molecular weight). What seems to be a true difference, though, is that the salt form is more stable, easier to formulate and cheaper so it pops up more often on the ingredient lis what‑it‑does skin-identical ingredient | moisturizer/humectant irritancy, com. soothing | moisturizer/humectant

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