Le Mieux Collagen Peptide Serum (Discontinued)

Le Mieux Collagen Peptide Serum (Discontinued) Le Mieux Collagen Peptide Serum ingredients explained: Hyaluronic Acid, Acetyl Tetrapeptide-2, Palmitoyl Oligopeptide, Palmitoyl Tetrapeptide-7, Palmitoyl Pentapeptide-4, Superoxide Dismutase, Epigallocatechin Gallatyl Glucoside, Teprenone, Ceramide Ii, Ceramide III, Hydrolyzed Avocado Protein, Maltodextrin, PEG-10 Rapeseed Sterol, Malus Domestica Fruit Cell Culture Extract, Camellia Sinensis (Green Tea) Leaf Extract, Tocotrienols (Vitamin E), Retinyl (Vitamin A) Palmitate, Sodium Palmitoyl Proline, Butyrospermum Parkii (Shea) Butter, Algae Extract, Dipalmitoyl Hydroxyproline, Sodium Carboxymethyl Beta-Glucan, Saccharomyces Lysate Extract, Glycine Soja (Soybean) Seed Extract, Glucose, Glucose Oxidase, Lactoperoxidase Show all ingredients by function Hyaluronic Acid skin-identical ingredient, moisturizer/​humectant goodie Acetyl Tetrapeptide-2 cell-communicating ingredient Palmitoyl Oligopeptide Palmitoyl Tetrapeptide-7 Palmitoyl Pentapeptide-4 Superoxide Dismutase antioxidant Epigallocatechin Gallatyl Glucoside antioxidant, soothing Teprenone Ceramide Ii skin-identical ingredient Ceramide III Hydrolyzed Avocado Protein Maltodextrin PEG-10 Rapeseed Sterol surfactant/​cleansing, emulsifying, surfactant/​cleansing Malus Domestica Fruit Cell Culture Extract Camellia Sinensis (Green Tea) Leaf Extract Tocotrienols (Vitamin E) Retinyl (Vitamin A) Palmitate 1-3, 1-3 Sodium Palmitoyl Proline Butyrospermum Parkii (Shea) Butter emollient Algae Extract emollient, moisturizer/​humectant Dipalmitoyl Hydroxyproline Sodium Carboxymethyl Beta-Glucan surfactant/​cleansing, viscosity controlling Saccharomyces Lysate Extract moisturizer/​humectant Glycine Soja (Soybean) Seed Extract antioxidant, skin brightening, soothing, emollient Glucose Glucose Oxidase Lactoperoxidase It’s naturally in our skin and behaves there like a sponge It can bind up to 1000 times its own weight in water It is a big molecule from repeated subunits (polymer) so different molecular weight versions exist (unfortunately there is no way to determine MW from INCI list only) High-molecular-weight-HA (>500 kDa) is an excellent surface hydrator, skin protectant and can act as an osmotic pump helping water-soluble actives to penetrate deeper into the skin Low-molecular-weight-HA (< 500 kDa) can hydrate the skin somewhat deeper though it is still a big molecule and works mainly in the epidermis (outer layer of the skin) Low-molecular-weight-HA might also help the skin to repair itself by increasing its self-defense (~ 200kDa used in the study) Ultra-low-molecular-weight-HA (<50kDa) is a controversial ingredient and might work as a pro-inflammatory signal molecule A four amino acid peptide that is claimed to mimic the youth hormone called thymopoietin. It works by compensating the loss of thymic factors that come with age and is thought to stimulate the skin immune defenses and to help the skin regenerate. A six amino acid peptide that is claimed to improve firmness and skin tone. Its amino acid sequence is Val-Gly-Val-Ala-Pro-Gly that is also called the "spring fragment" and is repeated six times in the important skin protein, elastin molecule. The manufacturer made a double-blind, one-month long clinical study on 10 women and found that twice a day application of 4% Biopeptide El improved skin firmness by 33% and skin tone by 20%. A four amino acid peptide with the amino sequence of glycine-glutamine-proline-arginine. It is attached to palmitic acid (a fatty acid) to increase oil solubility and skin penetration. It works by reducing the production of the signal molecule, interleukin-6 (IL-6) which promotes inflammation in the skin and less inflammation means slower degradation of important things (like collagen) that results in younger looking skin for a longer time. Expand to read more It works in synergy with its pal, Palmitoyl Tripeptide-1 in the famous Matrixyl 3000 complex. You can read some more about the famous duo here. A pretty famous and better-researched peptide consisting of five amino acids (the building blocks of all proteins). It was created in a joint effort by the French ingredient supplier, Sederma and the cosmetics industry big shot, Procter&Gamble. The amino acid sequence of the peptide is lysine–threonine–threonine–lysine–serine (KTTKS). Sometimes, it's also called collagen pentapeptide, as it's a subfragment of skin-structure-giving type I collagen. The KTTKS amino sequence is then attached for better oil solubility and skin penetration to palmitic acid and BOOM; we get Palmitoyl Pentapeptide-4. Though most research is manufacturer sponsored, the clinical studies about Palmitoyl Pentapeptide-4 are promising. In short, it can reduce fine lines, wrinkles and improve skin texture significantly (and at crazy low concentrations, what‑it‑does skin-identical ingredient | moisturizer/humectant antioxidant | soothing surfactant/cleansing | emulsifying | surfactant/cleansing irritancy, com. emollient | moisturizer/humectant surfactant/cleansing | viscosity controlling moisturizer/humectant antioxidant | skin brightening | soothing | emollient

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