Skin science article
Acure Incredibly Clear Azelaic Acid Facial Lotion Versus Paula's Choice 10% Azelaic Acid Booster
Acure Incredibly Clear Azelaic Acid Facial Lotion Versus Paula's Choice 10% Azelaic Acid Booster This acne moisturizer is formulated around Aloe Barbadensis Leaf Juice and Azelaic Acid to clear breakouts and calm redness. This calming treatment is formulated a
Acure Incredibly Clear Azelaic Acid Facial Lotion Versus Paula's Choice 10% Azelaic Acid Booster
This acne moisturizer is formulated around Aloe Barbadensis Leaf Juice and Azelaic Acid to clear breakouts and calm redness.
This calming treatment is formulated around Azelaic Acid and Salicylic Acid to calm redness and fade the look of dark spots.
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Cetearyl Alcohol
Carthamus Tinctorius Seed Oil
Glyceryl Stearate Citrate
Cocoglycerides
Aloe Barbadensis Leaf Juice
Helianthus Annuus Seed Oil
Glyceryl Laurate
Theobroma Cacao Seed Butter
Tocopherol
Tocopheryl Acetate
Azelaic Acid
Oenothera Biennis Oil
Argania Spinosa Kernel Oil
Chamomilla Recutita Flower Extract
Glycyrrhiza Glabra Root Extract
Calendula Officinalis Flower Extract
Mandelic Acid
Glycerin
Xanthan Gum
Sodium Levulinate
Glyceryl Caprylate
Sodium Phytate
Potassium Sorbate
Sodium Anisate
Citric Acid
Water, Cetearyl Alcohol, Carthamus Tinctorius Seed Oil, Glyceryl Stearate Citrate, Cocoglycerides, Aloe Barbadensis Leaf Juice, Helianthus Annuus Seed Oil, Glyceryl Laurate, Theobroma Cacao Seed Butter, Tocopherol, Tocopheryl Acetate, Azelaic Acid, Oenothera Biennis Oil, Argania Spinosa Kernel Oil, Chamomilla Recutita Flower Extract, Glycyrrhiza Glabra Root Extract, Calendula Officinalis Flower Extract, Mandelic Acid, Glycerin, Xanthan Gum, Sodium Levulinate, Glyceryl Caprylate, Sodium Phytate, Potassium Sorbate, Sodium Anisate, Citric Acid
C12-15 Alkyl Benzoate
Caprylic/Capric Triglyceride
Methyl Glucose Sesquistearate
Glyceryl Stearate
Dimethicone
Salicylic Acid
Adenosine
Boerhavia Diffusa Root Extract
Allantoin
Bisabolol
Cyclopentasiloxane
Sclerotium Gum
Propanediol
Butylene Glycol
Phenoxyethanol
Water, Azelaic Acid, C12-15 Alkyl Benzoate, Caprylic/Capric Triglyceride, Methyl Glucose Sesquistearate, Glycerin, Cetearyl Alcohol, Glyceryl Stearate, Dimethicone, Salicylic Acid, Adenosine, Glycyrrhiza Glabra Root Extract, Boerhavia Diffusa Root Extract, Allantoin, Bisabolol, Cyclopentasiloxane, Xanthan Gum, Sclerotium Gum, Propanediol, Butylene Glycol, Phenoxyethanol
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Alternatives
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Azelaic acid is a multitasker ingredient that helps treat acne, pigmentation, and irritation. It is a great option for sensitive skin.
What makes it special?
OTC Azelaic acid is usually available in concentrations from 10-15% and anything over requires a prescription.
Here's what each tier does best:
Unlike other acids, azelaic acid will not make your skin more photosensitive/sun sensitive.
Though this ingredient is naturally occurring in grains like wheat, rye, and barley, it is usually synthetically created for cosmetics to ensure stability and effectiveness.
Cetearyl alcohol is a waxy mixture of two fatty alcohols: cetyl alcohol and stearyl alcohol. It is an emollient and emulsifier.
Despite having "alcohol" in its name, it has nothing to do with drying solvent alcohols; the FDA also allows "alcohol-free" products to contain fatty alcohols like this ingredient.
It plays several roles in a formula:
Typical use levels for this ingredient sit around 1-10% and the Cosmetic Ingredient Review Expert Panel has affirmed safety at concentrations up to 25% in leave-on products.
Multiple assessments have found it to be non-irritating and non-sensitizing to most people.
However, there have been some cases of allergic contact dermatitis in patients with chronically compromised skin barriers.
Cetearyl alcohol has a comedogenic rating of 2 and irritancy rating of 1. Both of these numbers come from the 1989 study that used rabbit ears; a "2" means mildly comedogenic and a "1" means low irritancy.
Here's the catch: rabbit skin is more sensitive than human skin and throws a lot of false positives. A 1996 reappraisal found that ingredients rated 1-2 in the rabbit ear tests are generally safe for humans.
Remember comedogenic ratings are unable to assess the entire formula of a product or how it will react on your skin. Just be sure to patch test if you are unsure about certain ingredients.
This ingredient is not fungal acne safe. Cetearyl alcohol is a fatty alcohol with chain lengths that fall within the range that Malassezia can metabolize.
A 2019 study has also observed Malassezia growth in the presence of this ingredient, confirming it to be not-fungal acne safe.
Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Glycyrrhiza Glabra Root Extract is an extract of the roots of Licorice. It has been found to have several benefits such as skin hydrating, conditioning, and soothing.
One component, glabridin, has extra potent antioxidant and soothing properties. It has also been found to block pigmentation from UVB rays in guinea pigs.
Licorice Root also contains a flavonoid. Flavonoids are a natural substance from in plants. Flavonoids also have antioxidant properties.
Another component, glycyrrhizin, has been found to have anti-inflammatory and antimicrobial benefits. This may make licorice root extract effective at treating acne. However, more research is needed to support this.
Liquiritin is one of the flavone compounds found in licorice. It has been found to help lighten skin by preventing tyrosinase from reacting with tyrosine. When the two react, protein is converted to melanin. Melanin is the substance in your body that gives your features pigmentation.
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!
Xanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.
On the technical side of things, xanthan gum is a polysaccharide - a combination consisting of multiple sugar molecules bonded together.
Xanthan gum is a pretty common and great ingredient. It is a natural, non-toxic, non-irritating ingredient that is also commonly used in food products.