Skin science article
Algenist Complete Eye Renewal Balm Versus Allies of Skin Peptides & Omegas Firming Eye Cream
Algenist Complete Eye Renewal Balm Versus Allies of Skin Peptides & Omegas Firming Eye Cream This anti-aging eye moisturizer is formulated around Caffeine and Palmitoyl Tetrapeptide-7 to soften the look of wrinkles. This anti-aging eye moisturizer is formulate
Algenist Complete Eye Renewal Balm Versus Allies of Skin Peptides & Omegas Firming Eye Cream
This anti-aging eye moisturizer is formulated around Caffeine and Palmitoyl Tetrapeptide-7 to soften the look of wrinkles.
This anti-aging eye moisturizer is formulated around Squalane and Bakuchiol to soften the look of wrinkles and strengthen the skin barrier.
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Isopropyl Isostearate
Glycerin
Dimethicone
Palmitic Acid
Pentylene Glycol
Glyceryl Stearate Se
Stearic Acid
Dimethicone Crosspolymer
Butyrospermum Parkii Butter
Cetearyl Alcohol
Undaria Pinnatifida Extract
Limnanthes Alba Seed Oil
Parachlorella Beijerinckii Exopolysaccharides
Alaria Esculenta Extract
Bambusa Vulgaris Leaf/Stem Extract
Aloe Barbadensis Leaf Juice
Aloe Barbadensis Leaf Juice Powder
Camellia Sinensis Leaf Extract
Cucumis Sativus Fruit Extract
Tocopheryl Acetate
Caffeine
Tetrapeptide-21
Dipeptide-2
Palmitoyl Tetrapeptide-7
Palmitoyl Tripeptide-1
Magnesium Ascorbyl Phosphate
Malus Domestica Fruit Cell Culture Extract
Rubus Idaeus Leaf Extract
Glucosamine Hcl
Pisum Sativum Extract
Inula Crithmoide Extract
Phospholipids
Biotin
N-Hydroxysuccinimide
Chrysin
Hesperidin Methyl Chalcone
Lecithin
Caprylic/Capric Triglyceride
Leuconostoc/Radish Root Ferment Filtrate
Vinyl Dimethicone/Methicone Silsesquioxane Crosspolymer
Acrylates/C10-30 Alkyl Acrylate Crosspolymer
Steareth-20
Ceteareth-20
Butylene Glycol
Xanthan Gum
Sodium Citrate
Citric Acid
Disodium EDTA
Aminomethyl Propanol
Potassium Sorbate
Chlorhexidine Digluconate
Caprylyl Glycol
Hexylene Glycol
Ethylhexylglycerin
Sodium Benzoate
Phenoxyethanol
Water, Isopropyl Isostearate, Glycerin, Dimethicone, Palmitic Acid, Pentylene Glycol, Glyceryl Stearate Se, Stearic Acid, Dimethicone Crosspolymer, Butyrospermum Parkii Butter, Cetearyl Alcohol, Undaria Pinnatifida Extract, Limnanthes Alba Seed Oil, Parachlorella Beijerinckii Exopolysaccharides, Alaria Esculenta Extract, Bambusa Vulgaris Leaf/Stem Extract, Aloe Barbadensis Leaf Juice, Aloe Barbadensis Leaf Juice Powder, Camellia Sinensis Leaf Extract, Cucumis Sativus Fruit Extract, Tocopheryl Acetate, Caffeine, Tetrapeptide-21, Dipeptide-2, Palmitoyl Tetrapeptide-7, Palmitoyl Tripeptide-1, Magnesium Ascorbyl Phosphate, Malus Domestica Fruit Cell Culture Extract, Rubus Idaeus Leaf Extract, Glucosamine Hcl, Pisum Sativum Extract, Inula Crithmoide Extract, Phospholipids, Biotin, N-Hydroxysuccinimide, Chrysin, Hesperidin Methyl Chalcone, Lecithin, Caprylic/Capric Triglyceride, Leuconostoc/Radish Root Ferment Filtrate, Vinyl Dimethicone/Methicone Silsesquioxane Crosspolymer, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Steareth-20, Ceteareth-20, Butylene Glycol, Xanthan Gum, Sodium Citrate, Citric Acid, Disodium EDTA, Aminomethyl Propanol, Potassium Sorbate, Chlorhexidine Digluconate, Caprylyl Glycol, Hexylene Glycol, Ethylhexylglycerin, Sodium Benzoate, Phenoxyethanol
Tribehenin
Isodecyl Neopentanoate
Glyceryl Stearate
Propanediol
Squalane
Acrylamide/Sodium Acryloyldimethyltaurate Copolymer
Bakuchiol
Sodium Ascorbyl Phosphate
Ceramide NP
Rosa Canina Seed Oil
Adansonia Digitata Seed Oil
Argania Spinosa Kernel Oil
Glycyrrhiza Glabra Root Extract
Pfaffia Paniculata Root Extract
Ptychopetalum Olacoides Bark/Stem Extract
Calanthe Discolor Extract
Lilium Candidum Flower Extract
Ubiquinone
Superoxide Dismutase
Ergothioneine
Bisabolol
Allantoin
Methylglucoside Phosphate
Copper Lysinate/Prolinate
Gluconolactone
N-Prolyl Palmitoyl Tripeptide-56 Acetate
Calcium Gluconate
Caprylyl/Capryl Glucoside
Glyceryl Polyacrylate
Isohexadecane
Polysorbate 80
Sodium Gluconate
Sodium Hydroxide
Sorbitan Oleate
Benzyl Alcohol
Water, Glycerin, Tribehenin, Caprylic/Capric Triglyceride, Isodecyl Neopentanoate, Glyceryl Stearate, Propanediol, Squalane, Acrylamide/Sodium Acryloyldimethyltaurate Copolymer, Leuconostoc/Radish Root Ferment Filtrate, Caprylyl Glycol, Bakuchiol, Sodium Ascorbyl Phosphate, Ceramide NP, Rosa Canina Seed Oil, Adansonia Digitata Seed Oil, Argania Spinosa Kernel Oil, Glycyrrhiza Glabra Root Extract, Pfaffia Paniculata Root Extract, Ptychopetalum Olacoides Bark/Stem Extract, Calanthe Discolor Extract, Lilium Candidum Flower Extract, Ubiquinone, Superoxide Dismutase, Ergothioneine, Tocopheryl Acetate, Bisabolol, Allantoin, Biotin, Hesperidin Methyl Chalcone, Methylglucoside Phosphate, Copper Lysinate/Prolinate, Palmitoyl Tetrapeptide-7, Chrysin, Gluconolactone, Dipeptide-2, Palmitoyl Tripeptide-1, N-Prolyl Palmitoyl Tripeptide-56 Acetate, Calcium Gluconate, N-Hydroxysuccinimide, Caprylyl/Capryl Glucoside, Citric Acid, Glyceryl Polyacrylate, Isohexadecane, Pentylene Glycol, Polysorbate 80, Sodium Citrate, Sodium Gluconate, Sodium Hydroxide, Sorbitan Oleate, Steareth-20, Xanthan Gum, Benzyl Alcohol, Chlorhexidine Digluconate, Sodium Benzoate, Potassium Sorbate, Phenoxyethanol
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Alternatives
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Biotin is a B vitamin that is naturally produced by our bodies. It is also called Vitamin H.
Our bodies use biotin in the metabolism process. It also helps our bodies use enzymes and move nutrients around. A biotin deficiency can lead to brittle hair and nails.
More research is needed on applying biotin topically. However, taking biotin orally has been shown to help nourish the skin, hair, and nails. They play a role in forming skin-hydrating fatty acids.
Biotin is water-soluble. It can be found in foods such as fish, eggs, dairy, nuts, and meat. Vitamin H stands for "haar" and "haut". These are the German words for hair and skin.
Caprylic/Capric Triglyceride (aka MCT Oil) is a lightweight emollient, solvent, and texture enhancer. It is considered a skin-softener by helping to prevent moisture loss.
Though it behaves like an oil, it is not technically one due to its chemical composition. One perk of this ingredient is that it is very stable, resistant to oxidation, and unlikely to go rancid.
In practice, that translates to a long shelf life and a consistently elegant skin feel.
While there is an assumption Caprylic Triglyceride can clog pores due to it being derived from coconut oil, there is no research supporting this. Just patch test if you have concerns.
Fractionated coconut oil and MCT Oil are both listed as Caprylic/Capric Triglyceride according to INCI. This is because INCI names are based on the ingredient’s final chemical composition and not its marketing name or source.
This ingredient is treated as the gold standard fungal acne safe oil. Even though it is coconut derived, the problematic lauric acid is stripped out.
This leaves just caprylic (C8) and capric (C10) acid. These chain lengths actually trend antifungal; a 2020 study found caprylic acid was enough to disrupt Malassezia furfur cell membrane, with a caprylic acid derivative damaging membrane structures at concentrations as low as 0.2%.
Caprylyl Glycol is a humectant, skin conditioner, emollient, and preservative booster derived from either caprylic acid or synthetically created.
Typical use levels vary from 0.3-1% as a preservative booster and go up to 2% to condition skin.
Because it is not a free-fatty acid, this ingredient is fungal acne safe (there's nothing for Malassezia to feed on).
Chlorhexidine Digluconate is a preservative.
We don't have a description for Chrysin yet.
Citric Acid is an alpha hydroxy acid (AHA) naturally found in citrus fruits like oranges, lemons, and limes.
Like other AHAs, citric acid can exfoliate skin by breaking down the bonds that hold dead skin cells together. This helps reveal smoother and brighter skin underneath.
However, this exfoliating effect only happens at high concentrations (20%) which can be hard to find in cosmetic products.
Due to this, citric acid is usually included in small amounts as a pH adjuster. This helps keep products slightly more acidic and compatible with skin's natural pH.
In skincare formulas, citric acid can:
While it can provide some skin benefits, research shows lactic acid and glycolic acid are generally more effective and less irritating exfoliants.
Most citric acid used in skincare today is made by fermenting sugars (usually from molasses). This synthetic version is identical to the natural citrus form but easier to stabilize and use in formulations.
Rosacea skin has a lower threshold for acids generally, with 62.5% of rosacea subjects in one study reacting to lactic acid in a sting test. This is why we mark citric acid as a potential rosacea trigger.
However, this ingredient shows up as a pH adjuster or chelator at roughly 0.1-1% in many products. These low levels are unlikely to be an issue for rosacea skin and becomes a potential trigger at exfoliating concentrations (20%). Because everybody's skin is unique, we recommend a patch test if you are unsure.
Dipeptide-2 is a peptide. It can help to reduce the effects of aging.
Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Hesperidin Methyl Chalcone (HMC) is a modified form of hesperidin, a citrus flavonoid. It has antioxidant properties.
In preclinical research, HMC has been studied for its ability to reduce oxidative stress and inflammation related to UVB exposure. Outside of cosmetics, HMC has been looked at for its effects on capillary leakage and swelling. This is why you'll often see this ingredient in eye creams.
Overall, HMC is a gentle and supportive ingredient. Further research is needed on the claims that this ingredient can "erase dark circles".
Leuconostoc/Radish Root Ferment Filtrate is a natural preservative. It comes from fermenting radish roots with a bacteria called leuconostoc. The trade name for this ingredient is Leucidal.
Leuconostoc comes from lactic acid.
This ingredient has antimicrobial properties and helps prevent the growth of bacteria in a product.
Leuconostoc is used to make the traditional Korean side-dish, kimchi. It is also used to make sourdough bread (both incredibly yummy foods).
We don't have a description for N-Hydroxysuccinimide yet.
Palmitoyl Tetrapeptide-7 (formerly Palmitoyl Tetrapeptide-3) is a synthetic peptide. Its main job is to fight what researchers call "inflammaging".
"Inflammaging" is the slow, low-grade chronic inflammation that quietly breaks down collagen as we age.
This ingredient calms down a specific inflammation signal in your skin cells (called IL-6). When left unchecked, this signal triggers enzymes that break down collagen and elastin.
Clinical testing showed statistically significant improvements in:
Studies also found the more of this ingredient used, the more your skin produces Collagen I, fibronectin, and hyaluronic acid.
You'll likely see this ingredient paired with Palmitoyl Tripeptide-1 in the well-known Matrixyl 3000 complex for enhanced anti-aging effects.
A 3% concentration applied twice daily for two months showed meaningful skin rejuvenation results in clinical panels.
Fungal acne note: Usually a palmitic acid component can feed Malassezia in unbound form, but here is is covalently bonded to the peptide. This means it is very difficult for Malassezia to access, and therefore very unlikely to cause fungal acne.
Palmitoyl Tripeptide-1 (aka Pal-GHK) is a synthetic signal peptide made of three amino acids attached to palmitic acid.
That fatty acid attachment is the key: it boosts the peptide's ability to penetrate the skin barrier. This puts it closer to the dermal cells where it can actually make a difference.
Once there, it acts as a matrikine, a signaling peptide that prompts fibroblasts to produce more collagen, fibronectin, and hyaluronic acid.
In vitro studies show it can boost collagen production in skin cells even when UV-damaged skin samples were treated with it at a tiny concentration (it almost fully restored dermal collagen at 5ppm). It achieved this at 100x lower concentration than retinoic acid, which needed 500 ppm to do the same thing.
Human clinical data is promising, but modest:
A study of 23 female volunteers found a small but statistically significant increase (~4%) in skin thickness after treatment at 4 ppm.
A separate small trial of 15 women showed statistically significant reductions in wrinkle length, depth, and skin roughness after applying it twice daily for four weeks.
You'll likely see Pal-GHK paired with Palmitoyl Tetrapeptide-7 as part of the Matrixyl 3000 complex.
Pentylene Glycol (1,2-pentanediol) is a multitasking little diol with three main roles in a formula:
Research on alkanediols (the family pentylene glycol belongs to) show they work by disrupting microbial cell membranes. This disruption helps the primary preservative system in a product work more effectively at lower doses.
On the safety side, the Cosmetic Ingredient Review Expert Panel has concluded this ingredient to be safe as used in current cosmetic practices + concentrations.
Typical use levels in a formula run about 1-5%.
Phenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!).
It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome.
On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive.
Another perk of this ingredient is that it stays functional across a wide pH range (3-10).
You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own.
Typical use concentrations range from 0.3-1% depending on the formula, and this ingredient is capped at 1% int the EU.
Safety-wise, the fear mongering does not hold up to the evidence. The EU's Scientific Committee on Consumer Safety and FDA consider it safe as a preservative at up to 1%, including for children of all ages.
Adverse systemic effects only showed up in animal studies at exposures roughly 200x higher than what people get from cosmetics. And despite its very widespread use, this ingredient is a rare sensitizer and allergic reactions are uncommon.
Potassium Sorbate is a preservative used to prevent yeast and mold in products. It is commonly found in both cosmetic and food products.
This ingredient comes from potassium salt derived from sorbic acid. Sorbic acid is a natural antibiotic and effective against fungus.
Both potassium sorbate and sorbic acid can be found in baked goods, cheeses, dried meats, dried fruit, ice cream, pickles, wine, yogurt, and more.
You'll often find this ingredient used with other preservatives.
Sodium Benzoate is a preservative. It's used in both cosmetic and food products to inhibit the growth of mold and bacteria. It is typically produced synthetically.
Both the US FDA and EU Health Committee have approved the use of sodium benzoate. In the US, levels of 0.1% (of the total product) are allowed.
Sodium benzoate works as a preservative by inhibiting the growth of bacteria inside of cells. It prevents the cell from fermenting a type of sugar using an enzyme called phosphofructokinase.
It is the salt of benzoic acid. Foods containing sodium benzoate include soda, salad dressings, condiments, fruit juices, wines, and snack foods.
Studies for using ascorbic acid and sodium benzoate in cosmetics are lacking, especially in skincare routines with multiple steps.
We always recommend speaking with a professional, such as a dermatologist, if you have any concerns.
Sodium Citrate is the sodium salts of citric acid. In skincare, it is used to alter pH levels and acts as a preservative.
Its main functions are to maintain the pH of a product and neutralize metal ions.
The acidity of our skin is maintained by our glands and skin biome; normal pH level of skin is slightly acidic (~4.75-5.5).
Being slightly acidic allows our skin to create an "acid mantle". This acid mantle is a thin barrier that protects our skin from bacteria and contaminants.
Steareth-20 is an emulsifier and solubilizer. It is created from stearyl alcohol with ~20 units of ethylene oxide to give it a strong preference for water.
As an emulsifier, it helps oil-in-water emulsions like lotions, creams, and cleansers stay stable. It also solubilizes small amounts of oil-loving ingredients (like fragrance) into water-based formulas.
You'll likely find this ingredient with steareth-2 (it's oil-loving sister) where the two work together to give products a cushiony feel.
Typical use levels sit at around 1-5% and this ingredient has been found to be non-irritating by the CIR Expert Panel.
Tocopheryl Acetate is a stable, shelf-friendly form of vitamin E.
Formulators love it because plain vitamin E oxidizes quickly once it hits air. This acetate version stays stable and resists going off, helping to extend a product's shelf life.
It's actually inactive on its own and works like a slow-release "storage" form; the enzymes in your skin called esterases gradually convert it into active vitamin E over time.
One in vivo study showed 5% of the acetate in the living layer of the epidermis converted to vitamin E after 5 days of application. This study also found the skin gained protection against UV damage even though the conversion was slow and small.
Once converted, vitamin E acts as a skin's main fat-soluble antioxidant that fights free radicals to protect skin from damage.
Topical vitamin E generally boosts the skin's photoprotection, and it reduced UV-damage in animal models.
This ingredient has some brightening potential but it's more of a prevention ingredient than spot-fader. Cell studies show it can slow down melanin production but it's worth noting that it's not the most powerful brightener out there.
Overall, it has a pretty solid safety profile and has been found to be non-irritating and non-comedogenic. Allergic reactions may happen but stay rare due to how widely the ingredient gets used.
The concentration will vary depending on the formula; industry data shows 0.1% in baby lotions, 3% in lipsticks, and 5% in foot powders. You can also find this ingredient at 100% in a pure vitamin E oil.
Most leave-on skincare keeps it at the lower end, often between 0.5-1%.
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!
Xanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.
On the technical side of things, xanthan gum is a polysaccharide - a combination consisting of multiple sugar molecules bonded together.
Xanthan gum is a pretty common and great ingredient. It is a natural, non-toxic, non-irritating ingredient that is also commonly used in food products.