Skin science article
Allies of Skin Peptide & Antioxidants Firming Daily Treatment Versus Aramore NAD+ Cell Restoration Cream
Allies of Skin Peptide & Antioxidants Firming Daily Treatment Versus Aramore NAD+ Cell Restoration Cream This anti-aging moisturizer is formulated around Niacinamide and Tetrahexyldecyl Ascorbate to soften the look of wrinkles and calm redness. This anti-aging
Allies of Skin Peptide & Antioxidants Firming Daily Treatment Versus Aramore NAD+ Cell Restoration Cream
This anti-aging moisturizer is formulated around Niacinamide and Tetrahexyldecyl Ascorbate to soften the look of wrinkles and calm redness.
This anti-aging night moisturizer is formulated around Squalane and Niacinamide to soften the look of wrinkles and strengthen the skin barrier.
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Glycerin
Caprylic/Capric Triglyceride
Isononyl Isononanoate
Caffeine
C12-15 Alkyl Benzoate
Niacinamide
Lactobacillus Ferment
Cetearyl Olivate
Butylene Glycol
Polysorbate 60
Tetrahexyldecyl Ascorbate
Marrubium Vulgare Extract
Plantago Lanceolata Leaf Extract
Palmitoyl Tripeptide-5
Acetyl Tetrapeptide-40
Palmitoyl Tripeptide-8
Hydrolyzed Verbascum Thapsus Flower
Moringa Oleifera Seed Extract
Teprenone
Phospholipids
Hyaluronic Acid
Syringa Vulgaris Leaf Cell Culture Extract
Sphingolipids
Astaxanthin
Bisabolol
Euterpe Oleracea Fruit Oil
Rubus Idaeus Seed Oil
Honey
Dimethyl Isosorbide
Ceramide NP
Phenyl T-Butylnitrone
Tocopherol
Glutathione
Tetrahydrodiferuloylmethane
Tetrahydrodemethoxydiferuloylmethane
Tetrahydrobisdemethoxydiferuloylmethane
Ergothioneine
Xanthan Gum
Caprylyl Glycol
Carbomer
Sorbitan Olivate
Benzimidazole Diamond Amidoethyl Urea Carbamoyl Propyl Polymethylsilsesquioxane
Mica
Dextran
Citric Acid
Sodium Hydroxide
Acrylamide/Sodium Acryloyldimethyltaurate Copolymer
CI 77891
Ethylhexylglycerin
Isohexadecane
Maltodextrin
Polysorbate 80
Acetyl Tributyl Citrate
Tetrasodium EDTA
Sorbitan Oleate
Sodium Benzoate
Potassium Sorbate
Sodium Glycolate
Polysorbate 20
Phenoxyethanol
O-Cymen-5-Ol
Water, Glycerin, Caprylic/Capric Triglyceride, Isononyl Isononanoate, Caffeine, C12-15 Alkyl Benzoate, Niacinamide, Lactobacillus Ferment, Cetearyl Olivate, Butylene Glycol, Polysorbate 60, Tetrahexyldecyl Ascorbate, Marrubium Vulgare Extract, Plantago Lanceolata Leaf Extract, Palmitoyl Tripeptide-5, Acetyl Tetrapeptide-40, Palmitoyl Tripeptide-8, Hydrolyzed Verbascum Thapsus Flower, Moringa Oleifera Seed Extract, Teprenone, Phospholipids, Hyaluronic Acid, Syringa Vulgaris Leaf Cell Culture Extract, Sphingolipids, Astaxanthin, Bisabolol, Euterpe Oleracea Fruit Oil, Rubus Idaeus Seed Oil, Honey, Dimethyl Isosorbide, Ceramide NP, Phenyl T-Butylnitrone, Tocopherol, Glutathione, Tetrahydrodiferuloylmethane, Tetrahydrodemethoxydiferuloylmethane, Tetrahydrobisdemethoxydiferuloylmethane, Ergothioneine, Xanthan Gum, Caprylyl Glycol, Carbomer, Sorbitan Olivate, Benzimidazole Diamond Amidoethyl Urea Carbamoyl Propyl Polymethylsilsesquioxane, Mica, Dextran, Citric Acid, Sodium Hydroxide, Acrylamide/Sodium Acryloyldimethyltaurate Copolymer, CI 77891, Ethylhexylglycerin, Isohexadecane, Maltodextrin, Polysorbate 80, Acetyl Tributyl Citrate, Tetrasodium EDTA, Sorbitan Oleate, Sodium Benzoate, Potassium Sorbate, Sodium Glycolate, Polysorbate 20, Phenoxyethanol, O-Cymen-5-Ol
Pentylene Glycol
Squalane
Cetearyl Alcohol
Dicaprylyl Carbonate
Butyrospermum Parkii Butter
Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer
Nicotinamide Mononucleotide
Linoleic Acid
Linolenic Acid
Aspartic Acid
Arginine
Glycine
Alanine
Serine
Valine
Isoleucine
Proline
Threonine
Melatonin
Histidine
Phenylalanine
Tetrasodium Glutamate Diacetate
Sodium Hyaluronate
PCA
Sodium PCA
Sodium Lactate
Raspberry Ketone
Ascorbyl Glucoside
Citrus Paradisi Peel Extract
Hydrogenated Phosphatidylcholine
Lecithin
1,2-Hexanediol
Hexylene Glycol
Sodium Citrate
Water, Pentylene Glycol, Caprylic/Capric Triglyceride, Squalane, Cetearyl Alcohol, Niacinamide, Dicaprylyl Carbonate, Butyrospermum Parkii Butter, Cetearyl Olivate, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Sorbitan Olivate, Nicotinamide Mononucleotide, Linoleic Acid, Linolenic Acid, Aspartic Acid, Arginine, Glycine, Alanine, Serine, Valine, Isoleucine, Proline, Threonine, Melatonin, Histidine, Phenylalanine, Tetrasodium Glutamate Diacetate, Tocopherol, Sodium Hyaluronate, PCA, Sodium PCA, Sodium Lactate, Ceramide NP, Raspberry Ketone, Ascorbyl Glucoside, Citrus Paradisi Peel Extract, Hydrogenated Phosphatidylcholine, Lecithin, Glycerin, 1,2-Hexanediol, Hexylene Glycol, Ethylhexylglycerin, Caprylyl Glycol, Phenoxyethanol, Sodium Citrate, Sodium Hydroxide, Citric Acid
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Alternatives
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Caprylic/Capric Triglyceride (aka MCT Oil) is a lightweight emollient, solvent, and texture enhancer. It is considered a skin-softener by helping to prevent moisture loss.
Though it behaves like an oil, it is not technically one due to its chemical composition. One perk of this ingredient is that it is very stable, resistant to oxidation, and unlikely to go rancid.
In practice, that translates to a long shelf life and a consistently elegant skin feel.
While there is an assumption Caprylic Triglyceride can clog pores due to it being derived from coconut oil, there is no research supporting this. Just patch test if you have concerns.
Fractionated coconut oil and MCT Oil are both listed as Caprylic/Capric Triglyceride according to INCI. This is because INCI names are based on the ingredient’s final chemical composition and not its marketing name or source.
This ingredient is treated as the gold standard fungal acne safe oil. Even though it is coconut derived, the problematic lauric acid is stripped out.
This leaves just caprylic (C8) and capric (C10) acid. These chain lengths actually trend antifungal; a 2020 study found caprylic acid was enough to disrupt Malassezia furfur cell membrane, with a caprylic acid derivative damaging membrane structures at concentrations as low as 0.2%.
Caprylyl Glycol is a humectant, skin conditioner, emollient, and preservative booster derived from either caprylic acid or synthetically created.
Typical use levels vary from 0.3-1% as a preservative booster and go up to 2% to condition skin.
Because it is not a free-fatty acid, this ingredient is fungal acne safe (there's nothing for Malassezia to feed on).
Ceramide NP (formerly known as Ceramide 3) is one of the skin's naturally occurring lipids.
Since ceramides are the major lipid components of the skin, they are crucial for maintaining skin barrier and hydration. Ceramide NP most closely mirrors the dominant kind in human skin amongst ceramide subtypes.
This ceramide works by slotting into gaps within the stratum corneum's lipid matrix to limit trans-epidermal water loss (TEWL) and shield the skin against external irritants.
A study with 312 patients found that using a ceramide-containing routine for 4 weeks reduced the severity of atopic dermatitis by over 61%.
Another clinical study in subjects aged 60 and older found that a ceramide body wash and moisturizer improved skin dryness and itchy skin in 15 days.
Overall, ceramides are considered non-irritating and safety tests have found little to no observable adverse effects from using this ingredient.
Ceramide NP is usually sourced from plants (like soybean or rice bran), or produced synthetically.
Cetearyl Olivate is a plant-derived emulsifier and texture enhancer. It helps keep the oil and water phases from separating so your formulas stay stable.
You'll likely see it combined with Sorbitan Olivate (together sold as the trade name Olivem 1000). This combination generates a liquid crystal structure that closely resemble the lipid organization of the stratum corneum.
These "skin-like" liquid crystals improve skin barrier integrity and promote the delivery of actives into the skin.
This ingredient is well-tolerated and has no significant sensitization data.
Because it is derived from the fatty acids in olive oil, this ingredient may not be fungal acne safe.
Citric Acid is an alpha hydroxy acid (AHA) naturally found in citrus fruits like oranges, lemons, and limes.
Like other AHAs, citric acid can exfoliate skin by breaking down the bonds that hold dead skin cells together. This helps reveal smoother and brighter skin underneath.
However, this exfoliating effect only happens at high concentrations (20%) which can be hard to find in cosmetic products.
Due to this, citric acid is usually included in small amounts as a pH adjuster. This helps keep products slightly more acidic and compatible with skin's natural pH.
In skincare formulas, citric acid can:
While it can provide some skin benefits, research shows lactic acid and glycolic acid are generally more effective and less irritating exfoliants.
Most citric acid used in skincare today is made by fermenting sugars (usually from molasses). This synthetic version is identical to the natural citrus form but easier to stabilize and use in formulations.
Rosacea skin has a lower threshold for acids generally, with 62.5% of rosacea subjects in one study reacting to lactic acid in a sting test. This is why we mark citric acid as a potential rosacea trigger.
However, this ingredient shows up as a pH adjuster or chelator at roughly 0.1-1% in many products. These low levels are unlikely to be an issue for rosacea skin and becomes a potential trigger at exfoliating concentrations (20%). Because everybody's skin is unique, we recommend a patch test if you are unsure.
Ethylhexylglycerin is created from glycerin. It is a multitasker ingredient that:
The CIR Expert Panel found minimal skin absorption or sensitization of any kind in a safety assessment. Though this ingredient is considered well-tolerated, a small number of cases of allergic dermatitis have been published since 2002. Just be sure to patch test if you are unsure.
Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations.
Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Niacinamide is a multitasking form of vitamin B3 that strengthens the skin barrier, reduces pores and dark spots, regulates oil, and improves signs of aging.
And the best part? It's gentle and well-tolerated by most skin types, including sensitive and reactive skin.
You might have heard of "niacin flush", or the reddening of skin that causes itchiness. Niacinamide has not been found to cause this.
In very rare cases, some individuals may not be able to tolerate niacinamide at all or experience an allergic reaction to it.
If you are experiencing flaking, irritation, and dryness with this ingredient, be sure to double check all your products as this ingredient can be found in all categories of skincare.
When incorporating niacinamide into your routine, look out for concentration amounts. Typically, 5% niacinamide provides benefits such as fading dark spots. However, if you have sensitive skin, it is better to begin with a smaller concentration.
When you apply niacinamide to your skin, your body converts it into nicotinamide adenine dinucleotide (NAD). NAD is an essential coenzyme that is already found in your cells as "fuel" and powers countless biological processes.
In your skin, NAD helps repair cell damage, produce new healthy cells, support collagen production, strengthen the skin barrier, and fight environmental stressors (like UV and pollution).
Our natural NAD levels start to decline with age, leading to slower skin repair, visible aging, and a weaker skin barrier. By providing your skin niacinamide, you're recharging your skin's NAD levels. This leads to stronger, healthier, and younger looking skin.
Another name for vitamin B3 is nicotinamide. This vitamin is water-soluble and our bodies don't store it. We obtain Vitamin B3 from either food or skincare. Meat, fish, wheat, yeast, and leafy greens contain vitamin B3.
The type of niacinamide used in skincare is synthetically created.
Phenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!).
It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome.
On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive.
Another perk of this ingredient is that it stays functional across a wide pH range (3-10).
You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own.
Typical use concentrations range from 0.3-1% depending on the formula, and this ingredient is capped at 1% int the EU.
Safety-wise, the fear mongering does not hold up to the evidence. The EU's Scientific Committee on Consumer Safety and FDA consider it safe as a preservative at up to 1%, including for children of all ages.
Adverse systemic effects only showed up in animal studies at exposures roughly 200x higher than what people get from cosmetics. And despite its very widespread use, this ingredient is a rare sensitizer and allergic reactions are uncommon.
Sodium Hydroxide is also known as lye or caustic soda. It is used to adjust the pH of products; many ingredients require a specific pH to be effective.
In small amounts, sodium hydroxide is considered safe to use. However, large amounts may cause chemical burns due to its high alkaline.
Your skin has a natural pH and acid mantle. This acid mantle helps prevent harmful bacteria from breaking through. The acid mantle also helps keep your skin hydrated.
"Alkaline" refers to a high pH level. A low pH level would be considered acidic.
Sorbitan Olivate is created from the fatty acids in olive oil and sorbitol.
This ingredient is an oil in water emulsifier. It helps stabilize a product by preventing oils and waters from separating. Sorbitan Olivate also helps hydrate the skin.
This ingredient is also known as part of Olivem 1000, with Cetearyl Olivate being the other part.
According to a manufacturer, this ingredient helps preserve the natural microbiome of skin. Having a healthy microbiome helps keep our skin healthy and protects against harmful bacteria.
Please note, having a healthy microbiome is different from fungal acne; a healthy microbiome includes small amounts of yeast that normally live on your skin without causing problems.
Fungal acne happens when one type of yeast (Malassezia) grows out of control. This is usually because it's feeding on certain oils or fatty acids. Due to the olive oil base, this ingredient may not be fungal acne safe.
Tocopherol is a fat-soluble antioxidant known as Vitamin E.
You'll find this ingredient in the vast majority of skincare (for good reason). It works to neutralize free radicals, or unstable molecules generated by UV exposure, pollution, and other environmental stressors, before they can cause oxidative damage to your skin cells.
Topically applied tocopherol has been shown to protect against UV damage by ramping up the skin's own natural defense enzymes.
It also acts as a skin conditioning agent; some studies show that regular topical use can improve the skin's water-binding capacity over 2-4 weeks.
This ingredient is especially loved for being a team player. When combined with Vitamin C, the photoprotective effect of both ingredients roughly doubles and the combo also helps reduce UV-induced DNA damage.
This ingredient has some brightening potential but it's more of a prevention ingredient than spot-fader. Cell studies show it can slow down melanin production but it's worth noting that it's not the most powerful brightener out there.
In formulations, it also serves as a stabilizer that helps protect other oxidation-prone ingredients from degrading.
Concentrations usually range from 0.1-1% in most leave-on products.
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!