Skin science article
Allies of Skin Peptide & Antioxidants Firming Daily Treatment Versus SkinCeuticals Metacell Renewal B3
Allies of Skin Peptide & Antioxidants Firming Daily Treatment Versus SkinCeuticals Metacell Renewal B3 This anti-aging moisturizer is formulated around Niacinamide and Tetrahexyldecyl Ascorbate to soften the look of wrinkles and calm redness. This smoothing em
Allies of Skin Peptide & Antioxidants Firming Daily Treatment Versus SkinCeuticals Metacell Renewal B3
This anti-aging moisturizer is formulated around Niacinamide and Tetrahexyldecyl Ascorbate to soften the look of wrinkles and calm redness.
This smoothing emulsion is formulated around Niacinamide and Adenosine to refine skin texture and soften the look of wrinkles.
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Glycerin
Caprylic/Capric Triglyceride
Isononyl Isononanoate
Caffeine
C12-15 Alkyl Benzoate
Niacinamide
Lactobacillus Ferment
Cetearyl Olivate
Butylene Glycol
Polysorbate 60
Tetrahexyldecyl Ascorbate
Marrubium Vulgare Extract
Plantago Lanceolata Leaf Extract
Palmitoyl Tripeptide-5
Acetyl Tetrapeptide-40
Palmitoyl Tripeptide-8
Hydrolyzed Verbascum Thapsus Flower
Moringa Oleifera Seed Extract
Teprenone
Phospholipids
Hyaluronic Acid
Syringa Vulgaris Leaf Cell Culture Extract
Sphingolipids
Astaxanthin
Bisabolol
Euterpe Oleracea Fruit Oil
Rubus Idaeus Seed Oil
Honey
Dimethyl Isosorbide
Ceramide NP
Phenyl T-Butylnitrone
Tocopherol
Glutathione
Tetrahydrodiferuloylmethane
Tetrahydrodemethoxydiferuloylmethane
Tetrahydrobisdemethoxydiferuloylmethane
Ergothioneine
Xanthan Gum
Caprylyl Glycol
Carbomer
Sorbitan Olivate
Benzimidazole Diamond Amidoethyl Urea Carbamoyl Propyl Polymethylsilsesquioxane
Mica
Dextran
Citric Acid
Sodium Hydroxide
Acrylamide/Sodium Acryloyldimethyltaurate Copolymer
CI 77891
Ethylhexylglycerin
Isohexadecane
Maltodextrin
Polysorbate 80
Acetyl Tributyl Citrate
Tetrasodium EDTA
Sorbitan Oleate
Sodium Benzoate
Potassium Sorbate
Sodium Glycolate
Polysorbate 20
Phenoxyethanol
O-Cymen-5-Ol
Water, Glycerin, Caprylic/Capric Triglyceride, Isononyl Isononanoate, Caffeine, C12-15 Alkyl Benzoate, Niacinamide, Lactobacillus Ferment, Cetearyl Olivate, Butylene Glycol, Polysorbate 60, Tetrahexyldecyl Ascorbate, Marrubium Vulgare Extract, Plantago Lanceolata Leaf Extract, Palmitoyl Tripeptide-5, Acetyl Tetrapeptide-40, Palmitoyl Tripeptide-8, Hydrolyzed Verbascum Thapsus Flower, Moringa Oleifera Seed Extract, Teprenone, Phospholipids, Hyaluronic Acid, Syringa Vulgaris Leaf Cell Culture Extract, Sphingolipids, Astaxanthin, Bisabolol, Euterpe Oleracea Fruit Oil, Rubus Idaeus Seed Oil, Honey, Dimethyl Isosorbide, Ceramide NP, Phenyl T-Butylnitrone, Tocopherol, Glutathione, Tetrahydrodiferuloylmethane, Tetrahydrodemethoxydiferuloylmethane, Tetrahydrobisdemethoxydiferuloylmethane, Ergothioneine, Xanthan Gum, Caprylyl Glycol, Carbomer, Sorbitan Olivate, Benzimidazole Diamond Amidoethyl Urea Carbamoyl Propyl Polymethylsilsesquioxane, Mica, Dextran, Citric Acid, Sodium Hydroxide, Acrylamide/Sodium Acryloyldimethyltaurate Copolymer, CI 77891, Ethylhexylglycerin, Isohexadecane, Maltodextrin, Polysorbate 80, Acetyl Tributyl Citrate, Tetrasodium EDTA, Sorbitan Oleate, Sodium Benzoate, Potassium Sorbate, Sodium Glycolate, Polysorbate 20, Phenoxyethanol, O-Cymen-5-Ol
Dimethicone
Propanediol
Dimethicone/PEG-10/15 Crosspolymer
Methylsilanol/Silicate Crosspolymer
Sodium Chloride
Polymethylsilsesquioxane
Microcrystalline Cellulose
CI 77163
Chlorphenesin
Sodium Citrate
Ethylhexyl Hydroxystearate
PEG-10 Dimethicone
Disodium EDTA
Cellulose Gum
Laminaria Digitata Extract
Adenosine
Citrus Aurantium Amara Flower Oil
Melaleuca Viridiflora Leaf Oil
Tetradecyl Aminobutyroylvalylaminobutyric Urea Trifluoroacetate
Linalool
Cymbopogon Flexuosus Oil
Citral
Limonene
Pelargonium Graveolens Flower Oil
Water, Glycerin, Dimethicone, Niacinamide, Propanediol, Dimethicone/PEG-10/15 Crosspolymer, Methylsilanol/Silicate Crosspolymer, Sodium Chloride, Polymethylsilsesquioxane, Phenoxyethanol, Microcrystalline Cellulose, CI 77163, Chlorphenesin, Caprylyl Glycol, Sodium Citrate, Ethylhexyl Hydroxystearate, PEG-10 Dimethicone, Disodium EDTA, Cellulose Gum, Laminaria Digitata Extract, Adenosine, Citrus Aurantium Amara Flower Oil, Melaleuca Viridiflora Leaf Oil, Tetradecyl Aminobutyroylvalylaminobutyric Urea Trifluoroacetate, Linalool, Cymbopogon Flexuosus Oil, Citral, Limonene, Pelargonium Graveolens Flower Oil
Reviews
Be the first to review
Alternatives
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Caprylyl Glycol is a humectant, skin conditioner, emollient, and preservative booster derived from either caprylic acid or synthetically created.
Typical use levels vary from 0.3-1% as a preservative booster and go up to 2% to condition skin.
Because it is not a free-fatty acid, this ingredient is fungal acne safe (there's nothing for Malassezia to feed on).
Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Niacinamide is a multitasking form of vitamin B3 that strengthens the skin barrier, reduces pores and dark spots, regulates oil, and improves signs of aging.
And the best part? It's gentle and well-tolerated by most skin types, including sensitive and reactive skin.
You might have heard of "niacin flush", or the reddening of skin that causes itchiness. Niacinamide has not been found to cause this.
In very rare cases, some individuals may not be able to tolerate niacinamide at all or experience an allergic reaction to it.
If you are experiencing flaking, irritation, and dryness with this ingredient, be sure to double check all your products as this ingredient can be found in all categories of skincare.
When incorporating niacinamide into your routine, look out for concentration amounts. Typically, 5% niacinamide provides benefits such as fading dark spots. However, if you have sensitive skin, it is better to begin with a smaller concentration.
When you apply niacinamide to your skin, your body converts it into nicotinamide adenine dinucleotide (NAD). NAD is an essential coenzyme that is already found in your cells as "fuel" and powers countless biological processes.
In your skin, NAD helps repair cell damage, produce new healthy cells, support collagen production, strengthen the skin barrier, and fight environmental stressors (like UV and pollution).
Our natural NAD levels start to decline with age, leading to slower skin repair, visible aging, and a weaker skin barrier. By providing your skin niacinamide, you're recharging your skin's NAD levels. This leads to stronger, healthier, and younger looking skin.
Another name for vitamin B3 is nicotinamide. This vitamin is water-soluble and our bodies don't store it. We obtain Vitamin B3 from either food or skincare. Meat, fish, wheat, yeast, and leafy greens contain vitamin B3.
The type of niacinamide used in skincare is synthetically created.
Phenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!).
It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome.
On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive.
Another perk of this ingredient is that it stays functional across a wide pH range (3-10).
You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own.
Typical use concentrations range from 0.3-1% depending on the formula, and this ingredient is capped at 1% int the EU.
Safety-wise, the fear mongering does not hold up to the evidence. The EU's Scientific Committee on Consumer Safety and FDA consider it safe as a preservative at up to 1%, including for children of all ages.
Adverse systemic effects only showed up in animal studies at exposures roughly 200x higher than what people get from cosmetics. And despite its very widespread use, this ingredient is a rare sensitizer and allergic reactions are uncommon.
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!