Skin science article
alpyn beauty Super Peptide & Ghostberry Moisturizer Versus Kiehl's Ultra Facial Advanced Repair Barrier Cream
alpyn beauty Super Peptide & Ghostberry Moisturizer Versus Kiehl's Ultra Facial Advanced Repair Barrier Cream This anti-aging moisturizer is formulated around Acetyl Hexapeptide-8 and Ceramide NP to soften the look of wrinkles and strengthen the skin barrier.
alpyn beauty Super Peptide & Ghostberry Moisturizer Versus Kiehl's Ultra Facial Advanced Repair Barrier Cream
This anti-aging moisturizer is formulated around Acetyl Hexapeptide-8 and Ceramide NP to soften the look of wrinkles and strengthen the skin barrier.
This barrier-repair moisturizer is formulated around Niacinamide and Ceramide NP to strengthen the skin barrier and calm redness.
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Glycerin
Caprylic/Capric/Myristic/Stearic Triglyceride
Caprylic/Capric Triglyceride
Squalane
Candelilla/Jojoba/Rice Bran Polyglyceryl-3 Esters
Coconut Alkanes
C12-16 Alcohols
Propanediol
Polyhydroxystearic Acid
Behenyl Alcohol
Glyceryl Stearate
Cetearyl Alcohol
Symphoricarpos Albus Fruit Extract
Acetyl Hexapeptide-8
Acetyl Octapeptide-3
Ceramide NP
Ceramide EOP
Ceramide Ns
Ceramide As
Ceramide AP
Glyceryl Citrate/Lactate/Linoleate/Oleate
1,2-Hexanediol
Cetearyl Olivate
Hydrogenated Lecithin
Nephelium Lappaceum Peel Extract
Palmitic Acid
Sodium Stearoyl Lactylate
Sorbitan Olivate
Caprylhydroxamic Acid
Coco-Caprylate/Caprate
Xanthan Gum
Simmondsia Chinensis Seed Oil
Tasmannia Lanceolata Fruit/Leaf Extract
Bisabolol
Sodium Hyaluronate
Hydrolyzed Sodium Hyaluronate
Tripeptide-29
Hydrolyzed Pea Protein
2,3-Butanediol
Leuconostoc/Radish Root Ferment Filtrate
Hydrolyzed Rice Protein
Cholesterol
Sodium Benzoate
Water, Glycerin, Caprylic/Capric/Myristic/Stearic Triglyceride, Caprylic/Capric Triglyceride, Squalane, Candelilla/Jojoba/Rice Bran Polyglyceryl-3 Esters, Coconut Alkanes, C12-16 Alcohols, Propanediol, Polyhydroxystearic Acid, Behenyl Alcohol, Glyceryl Stearate, Cetearyl Alcohol, Symphoricarpos Albus Fruit Extract, Acetyl Hexapeptide-8, Acetyl Octapeptide-3, Ceramide NP, Ceramide EOP, Ceramide Ns, Ceramide As, Ceramide AP, Glyceryl Citrate/Lactate/Linoleate/Oleate, 1,2-Hexanediol, Cetearyl Olivate, Hydrogenated Lecithin, Nephelium Lappaceum Peel Extract, Palmitic Acid, Sodium Stearoyl Lactylate, Sorbitan Olivate, Caprylhydroxamic Acid, Coco-Caprylate/Caprate, Xanthan Gum, Simmondsia Chinensis Seed Oil, Tasmannia Lanceolata Fruit/Leaf Extract, Bisabolol, Sodium Hyaluronate, Hydrolyzed Sodium Hyaluronate, Tripeptide-29, Hydrolyzed Pea Protein, 2,3-Butanediol, Leuconostoc/Radish Root Ferment Filtrate, Hydrolyzed Rice Protein, Cholesterol, Sodium Benzoate
Butylene Glycol
Pentylene Glycol
Niacinamide
Dicaprylyl Carbonate
Trehalose
Sucrose Polystearate
Acrylates/C10-30 Alkyl Acrylate Crosspolymer
Tromethamine
Tocopherol
Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer
Allantoin
Hydrogenated Polyisobutene
Carbomer
Beta-Glucan
Ethylhexylglycerin
Adenosine
Caprylyl Glycol
Pseudoalteromonas Ferment Extract
Sorbitan Isostearate
Cetyl Palmitate
Cynanchum Atratum Extract
Colloidal Oatmeal
Sorbitan Palmitate
C14-22 Alcohols
C12-20 Alkyl Glucoside
Salicylic Acid
Sodium Hydroxide
Water, Butylene Glycol, Glycerin, Caprylic/Capric Triglyceride, Behenyl Alcohol, Pentylene Glycol, Niacinamide, Dicaprylyl Carbonate, Cetearyl Alcohol, Trehalose, Sucrose Polystearate, C12-16 Alcohols, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Tromethamine, Tocopherol, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Ceramide NP, Allantoin, Hydrogenated Polyisobutene, Palmitic Acid, Hydrogenated Lecithin, Carbomer, Beta-Glucan, Ethylhexylglycerin, Adenosine, Caprylyl Glycol, Pseudoalteromonas Ferment Extract, Sorbitan Isostearate, Cetyl Palmitate, Cynanchum Atratum Extract, Colloidal Oatmeal, Sorbitan Olivate, Sorbitan Palmitate, C14-22 Alcohols, C12-20 Alkyl Glucoside, Salicylic Acid, Sodium Hydroxide
Reviews
Alternatives
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Behenyl Alcohol is a type of fatty alcohol (these are different from the drying, solvent alcohols).
Fatty Alcohols have hydrating properties and are most often used as an emollient or to thicken a product. They are usually derived from natural fats and oils; behenyl alcohol is derived from the fats of vegetable oils.
Emollients help keep your skin soft and hydrated by creating a film that traps moisture in.
In 2000, Behenyl Alcohol was approved by the US as medicine to reduce the duration of cold sores.
We don't have a description for C12-16 Alcohols yet.
Caprylic/Capric Triglyceride (aka MCT Oil) is a lightweight emollient, solvent, and texture enhancer. It is considered a skin-softener by helping to prevent moisture loss.
Though it behaves like an oil, it is not technically one due to its chemical composition. One perk of this ingredient is that it is very stable, resistant to oxidation, and unlikely to go rancid.
In practice, that translates to a long shelf life and a consistently elegant skin feel.
While there is an assumption Caprylic Triglyceride can clog pores due to it being derived from coconut oil, there is no research supporting this. Just patch test if you have concerns.
Fractionated coconut oil and MCT Oil are both listed as Caprylic/Capric Triglyceride according to INCI. This is because INCI names are based on the ingredient’s final chemical composition and not its marketing name or source.
This ingredient is treated as the gold standard fungal acne safe oil. Even though it is coconut derived, the problematic lauric acid is stripped out.
This leaves just caprylic (C8) and capric (C10) acid. These chain lengths actually trend antifungal; a 2020 study found caprylic acid was enough to disrupt Malassezia furfur cell membrane, with a caprylic acid derivative damaging membrane structures at concentrations as low as 0.2%.
Ceramide NP (formerly known as Ceramide 3) is one of the skin's naturally occurring lipids.
Since ceramides are the major lipid components of the skin, they are crucial for maintaining skin barrier and hydration. Ceramide NP most closely mirrors the dominant kind in human skin amongst ceramide subtypes.
This ceramide works by slotting into gaps within the stratum corneum's lipid matrix to limit trans-epidermal water loss (TEWL) and shield the skin against external irritants.
A study with 312 patients found that using a ceramide-containing routine for 4 weeks reduced the severity of atopic dermatitis by over 61%.
Another clinical study in subjects aged 60 and older found that a ceramide body wash and moisturizer improved skin dryness and itchy skin in 15 days.
Overall, ceramides are considered non-irritating and safety tests have found little to no observable adverse effects from using this ingredient.
Ceramide NP is usually sourced from plants (like soybean or rice bran), or produced synthetically.
Cetearyl alcohol is a waxy mixture of two fatty alcohols: cetyl alcohol and stearyl alcohol. It is an emollient and emulsifier.
Despite having "alcohol" in its name, it has nothing to do with drying solvent alcohols; the FDA also allows "alcohol-free" products to contain fatty alcohols like this ingredient.
It plays several roles in a formula:
Typical use levels for this ingredient sit around 1-10% and the Cosmetic Ingredient Review Expert Panel has affirmed safety at concentrations up to 25% in leave-on products.
Multiple assessments have found it to be non-irritating and non-sensitizing to most people.
However, there have been some cases of allergic contact dermatitis in patients with chronically compromised skin barriers.
Cetearyl alcohol has a comedogenic rating of 2 and irritancy rating of 1. Both of these numbers come from the 1989 study that used rabbit ears; a "2" means mildly comedogenic and a "1" means low irritancy.
Here's the catch: rabbit skin is more sensitive than human skin and throws a lot of false positives. A 1996 reappraisal found that ingredients rated 1-2 in the rabbit ear tests are generally safe for humans.
Remember comedogenic ratings are unable to assess the entire formula of a product or how it will react on your skin. Just be sure to patch test if you are unsure about certain ingredients.
This ingredient is not fungal acne safe. Cetearyl alcohol is a fatty alcohol with chain lengths that fall within the range that Malassezia can metabolize.
A 2019 study has also observed Malassezia growth in the presence of this ingredient, confirming it to be not-fungal acne safe.
Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Hydrogenated Lecithin is a more stable version of lecithin.
It's made by taking lecithin (a phospholipid commonly found in soybeans and egg yolks) and hydrogenating it. This just means the unsaturated fatty acids are turned into saturated ones so they don't go bad as easily.
This ingredient is an emollient, emulsifier, and penetration enhancer. As an emollient, it helps soften and hydrate skin by trapping moisture within. As an emulsifier, it prevents oil and water ingredients from separating.
Hydrogenated Lecithin can form tiny spherical structures made of phospholipid bilayers called liposomes. These liposomes are able to capture compounds inside their structure and deliver them through the skin barrier.
Because phospholipids are a natural component of our cell membranes, this ingredient is inherently compatible with skin.
A 2021 study found lecithin-based surfactants were less harsh and more tolerable comared to Sodium Lauryl Sulfate (SLS).
Palmitic Acid is a fatty acid naturally found in our skin and in many plant and animal sources.
In cosmetics, it is usually derived from palm oil. It serves many purposes in skincare, acting as a cleanser, emollient, and emulsifier.
Interestingly, topically applied Palmitic Acid can be elongated into longer chain fatty acids and ceramides. A 2019 study found low levels of Palmitic Acid lead to slower development of cells, suggesting it plays a role in keeping your skin's renewal process on track.
The CIR (Cosmetic Ingredient Review) panel determined it safe as used in cosmetics at concentrations up to 13%. It is non-irritating and non-sensitizing in clinical studies.
The culprit behind fungal acne, the Malassezia yeast, feeds on fatty acids with carbon chain lengths between C11-C24. Palmitic Acid, at C16, falls right into that sweet spot.
In vitro studies have shown that Palmitic Acid is one of the fatty acids that induce rapid Malassezia growth in lab settings.
It's worth noting that what feeds yeast in a lab doesn't necessarily feed it on your face since formulation and your skin's chemistry play a bigger role.
Sorbitan Olivate is created from the fatty acids in olive oil and sorbitol.
This ingredient is an oil in water emulsifier. It helps stabilize a product by preventing oils and waters from separating. Sorbitan Olivate also helps hydrate the skin.
This ingredient is also known as part of Olivem 1000, with Cetearyl Olivate being the other part.
According to a manufacturer, this ingredient helps preserve the natural microbiome of skin. Having a healthy microbiome helps keep our skin healthy and protects against harmful bacteria.
Please note, having a healthy microbiome is different from fungal acne; a healthy microbiome includes small amounts of yeast that normally live on your skin without causing problems.
Fungal acne happens when one type of yeast (Malassezia) grows out of control. This is usually because it's feeding on certain oils or fatty acids. Due to the olive oil base, this ingredient may not be fungal acne safe.
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!