Skin science article
APLB Azelaic Acid Peptide Ampoule Serum Versus Glow Recipe Pomegranate Peptide Firming Serum
APLB Azelaic Acid Peptide Ampoule Serum Versus Glow Recipe Pomegranate Peptide Firming Serum This calming ampoule is formulated around Azelaic Acid and Sh-Oligopeptide-1 to calm redness and fade the look of dark spots. This anti-aging serum is formulated aroun
APLB Azelaic Acid Peptide Ampoule Serum Versus Glow Recipe Pomegranate Peptide Firming Serum
This calming ampoule is formulated around Azelaic Acid and Sh-Oligopeptide-1 to calm redness and fade the look of dark spots.
This anti-aging serum is formulated around Copper Tripeptide-1 and Punica Granatum Fruit Extract to soften the look of wrinkles and strengthen the skin barrier.
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Centella Asiatica Leaf Water
Butylene Glycol
Propanediol
Glycerin
Diethoxyethyl Succinate
Azelaic Acid
Sh-Oligopeptide-1
Madecassic Acid
Asiaticoside
Asiatic Acid
Squalane
Solanum Melongena Fruit Extract
Melaleuca Alternifolia Leaf Extract
Beta-Glucan
Hippophae Rhamnoides Fruit Extract
Nelumbo Nucifera Extract
Artemisia Annua Extract
Oryza Sativa Extract
Saccharomyces Ferment
Dipropylene Glycol
Sodium Citrate
Sodium Hyaluronate
Allantoin
Cellulose Gum
Disodium EDTA
Glyceryl Acrylate/Acrylic Acid Copolymer
Citric Acid
Xanthan Gum
Inulin
Cellulose
Glucose
Fructose
Panthenol
Ethylhexylglycerin
Hydroxyacetophenone
Sodium Polyacryloyldimethyl Taurate
Dipotassium Glycyrrhizate
1,2-Hexanediol
Water, Centella Asiatica Leaf Water, Butylene Glycol, Propanediol, Glycerin, Diethoxyethyl Succinate, Azelaic Acid, Sh-Oligopeptide-1, Madecassic Acid, Asiaticoside, Asiatic Acid, Squalane, Solanum Melongena Fruit Extract, Melaleuca Alternifolia Leaf Extract, Beta-Glucan, Hippophae Rhamnoides Fruit Extract, Nelumbo Nucifera Extract, Artemisia Annua Extract, Oryza Sativa Extract, Saccharomyces Ferment, Dipropylene Glycol, Sodium Citrate, Sodium Hyaluronate, Allantoin, Cellulose Gum, Disodium EDTA, Glyceryl Acrylate/Acrylic Acid Copolymer, Citric Acid, Xanthan Gum, Inulin, Cellulose, Glucose, Fructose, Panthenol, Ethylhexylglycerin, Hydroxyacetophenone, Sodium Polyacryloyldimethyl Taurate, Dipotassium Glycyrrhizate, 1,2-Hexanediol
Acacia Senegal Gum
Pullulan
Copper Tripeptide-1
Sr-Hydrozoan Polypeptide-1
Punica Granatum Seed Oil
Punica Granatum Fruit Extract
Hyaluronic Acid
Ethylhexyl Palmitate
Tocopherol
Lactobacillus/Punica Granatum Fruit Ferment Extract
Elastin
Bidens Pilosa Extract
Linum Usitatissimum Seed Oil
Enteromorpha Compressa Extract
Engelhardtia Chrysolepis Leaf Extract
Ocimum Sanctum Leaf Extract
Silybum Marianum Fruit Extract
Leuconostoc/Radish Root Ferment Filtrate
Gossypium Herbaceum Seed Oil
Tetrasodium Glutamate Diacetate
Trihydroxystearin
Dilauryl Citrate
Polyglyceryl-4 Laurate
Polyacrylate Crosspolymer-6
Rhizobian Gum
Elaeis Guineensis Oil
Polymethylsilsesquioxane
Sorbitan Laurate
Glucomannan
Phenoxyethanol
Potassium Sorbate
Sodium Hydroxide
Parfum
Water, Propanediol, Glycerin, Acacia Senegal Gum, Pullulan, Squalane, Copper Tripeptide-1, Sr-Hydrozoan Polypeptide-1, Punica Granatum Seed Oil, Punica Granatum Fruit Extract, Hyaluronic Acid, Sodium Hyaluronate, Ethylhexyl Palmitate, Tocopherol, Lactobacillus/Punica Granatum Fruit Ferment Extract, Elastin, Bidens Pilosa Extract, Linum Usitatissimum Seed Oil, Enteromorpha Compressa Extract, Engelhardtia Chrysolepis Leaf Extract, Ocimum Sanctum Leaf Extract, Silybum Marianum Fruit Extract, Leuconostoc/Radish Root Ferment Filtrate, Gossypium Herbaceum Seed Oil, Tetrasodium Glutamate Diacetate, Trihydroxystearin, 1,2-Hexanediol, Dilauryl Citrate, Polyglyceryl-4 Laurate, Polyacrylate Crosspolymer-6, Rhizobian Gum, Elaeis Guineensis Oil, Polymethylsilsesquioxane, Sorbitan Laurate, Glucomannan, Ethylhexylglycerin, Phenoxyethanol, Potassium Sorbate, Citric Acid, Sodium Hydroxide, Parfum
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Alternatives
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
1,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse.
It is a:
Humectant, drawing moisture into the skin
Emollient, helping to soften skin
Solvent, dispersing and stabilizing formulas
Preservative booster, enhancing the antimicrobial activity of other preservatives
Citric Acid is an alpha hydroxy acid (AHA) naturally found in citrus fruits like oranges, lemons, and limes.
Like other AHAs, citric acid can exfoliate skin by breaking down the bonds that hold dead skin cells together. This helps reveal smoother and brighter skin underneath.
However, this exfoliating effect only happens at high concentrations (20%) which can be hard to find in cosmetic products.
Due to this, citric acid is usually included in small amounts as a pH adjuster. This helps keep products slightly more acidic and compatible with skin's natural pH.
In skincare formulas, citric acid can:
While it can provide some skin benefits, research shows lactic acid and glycolic acid are generally more effective and less irritating exfoliants.
Most citric acid used in skincare today is made by fermenting sugars (usually from molasses). This synthetic version is identical to the natural citrus form but easier to stabilize and use in formulations.
Rosacea skin has a lower threshold for acids generally, with 62.5% of rosacea subjects in one study reacting to lactic acid in a sting test. This is why we mark citric acid as a potential rosacea trigger.
However, this ingredient shows up as a pH adjuster or chelator at roughly 0.1-1% in many products. These low levels are unlikely to be an issue for rosacea skin and becomes a potential trigger at exfoliating concentrations (20%). Because everybody's skin is unique, we recommend a patch test if you are unsure.
Ethylhexylglycerin is created from glycerin. It is a multitasker ingredient that:
The CIR Expert Panel found minimal skin absorption or sensitization of any kind in a safety assessment. Though this ingredient is considered well-tolerated, a small number of cases of allergic dermatitis have been published since 2002. Just be sure to patch test if you are unsure.
Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations.
Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Propanediol is an all-star ingredient. It softens, hydrates, and smooths the skin.
It’s often used to:
Propanediol is not likely to cause sensitivity and considered safe to use. It is derived from corn or petroleum with a clear color and no scent.
Sodium Hyaluronate is the salt form of hyaluronic acid. It is a long sugar chain that is naturally found in your skin, joints, and connective tissue that maintains hydration and elasticity.
In skincare, it works as a humectant. It pulls water from the environment and deeper layers of skin and binds it to the surface.
Interestingly, the size of the molecule affects its behavior:
Some clinical evidence links low molecular weight versions to improved wrinkle depth, elasticity, anti-inflammatory effects, and barrier repair.
Many serums use a blend of both weights so you can get surface hydration plus longer-lasting and deeper effects.
You'll typically see concentrations between 0.1-2% for this ingredient.
Squalane is the hydrogenated and shelf-stable form of squalene (a lipid that naturally occurs in human sebum).
It is an emollient and skin conditioning agent that is able to integrate seamlessly into the skin's lipid barrier without clogging pores.
This is due to how structurally similar it is to what your skin already produces.
Though it is mostly an emollient that helps soften and hydrate skin, it also has some humectant and occlusive action. Humectants help the skin retain moisture while occlusives seal it in, making squalane a triple-threat moisturizer.
Research shows it has antioxidant capabilities that help protect against stressors like UV exposure, specifically UVA induced oxidative stress. This study also found that it supports collagen biosynthesis in human dermal fibroblasts.
No clinical study has reported significant adverse effects and irritation reactions are very rare from this ingredient (even at 100% concentration).
Overall, it's a fantastic ingredient for hydration and is suitable for all skin types.
This depends on the source. Squalane can be derived from both plants and animals. Most squalane used in skincare comes from plants.
Please note: the source of squalane is only known if disclosed by the brand. We recommend reaching out to the brand if you have any questions about their squalane.
Read more about squalene with an "e".
Though squalane is often called an oil, it’s technically not one. It is a hydrocarbon, meaning it is only made of carbon and hydrogen. True oils are triglycerides and made of fatty acids and glycerol.
The term “oil-free” isn’t regulated so companies can define it however they want. Some exclude all oils, while others just avoid mineral oil or comedogenic oils.
Squalane has a comedogenic rating of 1 from the original 1972 study that tested raw ingredients under occlusion on rabbit ears. This system is not standardized or peer-reviewed, and using the raw ingredients is very different from how diluted cosmetic formulations are used on human skin.
A comedogenic rating of 1 means it is "unlikely to clog pores" according to the original rating system.
The overall formula of a product matters more than the individual ingredients on whether or not it will cause clogged pores.
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!