Skin science article
Beauty of Joseon Calming Serum: Green Tea + Panthenol Versus Numbuzin No.1 Pantothenic B5 Active Soothing Serum
Beauty of Joseon Calming Serum: Green Tea + Panthenol Versus Numbuzin No.1 Pantothenic B5 Active Soothing Serum This calming serum is formulated around Panthenol and Dipotassium Glycyrrhizate to calm redness and strengthen the skin barrier. This calming serum
Beauty of Joseon Calming Serum: Green Tea + Panthenol Versus Numbuzin No.1 Pantothenic B5 Active Soothing Serum
This calming serum is formulated around Panthenol and Dipotassium Glycyrrhizate to calm redness and strengthen the skin barrier.
This calming serum is formulated around Niacinamide and Panthenol to calm redness and balance excess oil.
What's inside
Key Ingredients
Benefits
Concerns
No concerns
Ingredients Side-by-side
Water
Panthenol
Glycerin
Butylene Glycol
1,2-Hexanediol
Methylpropanediol
Camellia Sinensis Leaf Water
Acrylates/C10-30 Alkyl Acrylate Crosspolymer
Tromethamine
Betaine
Ethylhexylglycerin
Allantoin
Dipotassium Glycyrrhizate
Artemisia Capillaris Extract
Glyceryl Acrylate/Acrylic Acid Copolymer
Melia Azadirachta Leaf Extract
Polyquaternium-51
Malt Extract
Melia Azadirachta Flower Extract
Coptis Japonica Root Extract
Sodium Hyaluronate
Water, Panthenol, Glycerin, Butylene Glycol, 1,2-Hexanediol, Methylpropanediol, Camellia Sinensis Leaf Water, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Tromethamine, Betaine, Ethylhexylglycerin, Allantoin, Dipotassium Glycyrrhizate, Artemisia Capillaris Extract, Glyceryl Acrylate/Acrylic Acid Copolymer, Melia Azadirachta Leaf Extract, Polyquaternium-51, Malt Extract, Melia Azadirachta Flower Extract, Coptis Japonica Root Extract, Sodium Hyaluronate
Niacinamide
Dipropylene Glycol
Sophora Angustifolia Root Extract
Propanediol
Diethoxyethyl Succinate
Hydrogenated Lecithin
Ammonium Acryloyldimethyltaurate/Vp Copolymer
Pantothenic Acid
Trehalose
Glyceryl Oleate
Sodium Phytate
Alpha-Arbutin
Houttuynia Cordata Extract
Lauryl Glucoside
Myristyl Glucoside
Polyglyceryl-6 Laurate
Zinc PCA
Tocopherol
Glycyrrhiza Uralensis Root Extract
Coccinia Indica Fruit Extract
Centella Asiatica Extract
Citric Acid
Solanum Melongena Fruit Extract
Beta-Glucan
Ocimum Sanctum Leaf Extract
Hyaluronic Acid
Decyl Glucoside
Curcuma Longa Root Extract
Corallina Officinalis Extract
Hydrolyzed Hyaluronic Acid
Simmondsia Chinensis Seed Oil
Camellia Sinensis Leaf Extract
Centella Asiatica Leaf Extract
Cladosiphon Okamuranus Extract
Salix Alba Bark Extract
Sodium Acetylated Hyaluronate
Coffea Arabica Seed Extract
Beta-Sitosterol
Polyglyceryl-10 Stearate
Citrus Aurantium Bergamia Leaf Extract
Pinus Densiflora Leaf Extract
Water, Butylene Glycol, Niacinamide, Glycerin, Dipropylene Glycol, 1,2-Hexanediol, Panthenol, Sophora Angustifolia Root Extract, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Propanediol, Diethoxyethyl Succinate, Tromethamine, Hydrogenated Lecithin, Ammonium Acryloyldimethyltaurate/Vp Copolymer, Betaine, Pantothenic Acid, Trehalose, Ethylhexylglycerin, Glyceryl Oleate, Sodium Phytate, Allantoin, Alpha-Arbutin, Houttuynia Cordata Extract, Lauryl Glucoside, Myristyl Glucoside, Polyglyceryl-6 Laurate, Zinc PCA, Melia Azadirachta Leaf Extract, Tocopherol, Glycyrrhiza Uralensis Root Extract, Melia Azadirachta Flower Extract, Coccinia Indica Fruit Extract, Centella Asiatica Extract, Sodium Hyaluronate, Citric Acid, Solanum Melongena Fruit Extract, Beta-Glucan, Ocimum Sanctum Leaf Extract, Hyaluronic Acid, Decyl Glucoside, Curcuma Longa Root Extract, Corallina Officinalis Extract, Dipotassium Glycyrrhizate, Hydrolyzed Hyaluronic Acid, Simmondsia Chinensis Seed Oil, Camellia Sinensis Leaf Extract, Centella Asiatica Leaf Extract, Cladosiphon Okamuranus Extract, Salix Alba Bark Extract, Sodium Acetylated Hyaluronate, Coffea Arabica Seed Extract, Beta-Sitosterol, Polyglyceryl-10 Stearate, Citrus Aurantium Bergamia Leaf Extract, Pinus Densiflora Leaf Extract
Reviews
Alternatives
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
1,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse.
It is a:
Humectant, drawing moisture into the skin
Emollient, helping to soften skin
Solvent, dispersing and stabilizing formulas
Preservative booster, enhancing the antimicrobial activity of other preservatives
Acrylates/C10-30 Alkyl Acrylate Crosspolymer is a synthetic polymer. It is used to thicken, emulsify, and improve the texture of products.
As an emulsifier, it helps stabilize oil-in-water emulsions to give products an elegant feel when applied.
It can also form a thin protective film on skin. One study found that a formula using this polymer helped slow down how quickly other ingredients (like DEET) were absorbed through skin.
A 2024 study of over 1,300 patients confirmed that sensitization to this ingredient is rare. It is also non-mutagenic and has a clean track record.
Allantoin is a soothing ingredient known for its protective and moisturizing properties; it's basically a quiet workhorse ingredient you can find in a huge range of cosmetics.
Though it can be derived from the comfrey plant, allantoin is produced synthetically for cosmetic products to ensure purity.
Research shows it can encourage your skin cells to turn over and renew by stimulating keratinocyte and fibroblast proliferation.
It also has mild keratolytic properties to help loosen and shed dead skin cells without being harsh.
Studies also suggest allantoin can help calm inflammation by dialing down some of the chemical signals your skin sends out when it is irritated.
This ingredient is typically used in the 0.1-0.5% range, and the FDA recognizes it as a skin protectant in OTC products up to 2%.
Overall, allantoin is a wonderful addition to most routines; it is stable across a wide pH range (~4-8), works well with other ingredients, and is considered non-sensitizing/non-irritating.
Fun fact: Allantoin is naturally occurring in comfrey root, beets, chamomile, and wheat sprouts. Our bodies even produce it as a byproduct of uric acid metabolism.
Betaine is a humectant. Like hyaluronic acid, it helps attract and retain moisture in the skin. It’s known for being gentle and for helping the skin maintain balanced hydration.
Betaine is mainly used to improve hydration and support calmer skin. It helps skin cells regulate water balance because it functions as an osmolyte.
Some studies suggest betaine may support making skin tone more even.
Fun fact: Betaine naturally exists in the skin and the body. In cosmetic products, it can be either plant-derived (most commonly from sugar beets) or synthetically produced for consistency and stability.
Betaine is also known as trimethylglycine.
Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:
Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.
Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.
Dipotassium Glycyrrhizate comes from licorice root.
Extracts of licorice have demonstrated to have antibacterial, anti‐inflammatory, antiviral, antioxidant properties.
One component, glabridin, has extra potent antioxidant and soothing properties. It has also been found to block pigmentation from UVB rays in guinea pigs.
Licorice Root also contains a flavonoid. Flavonoids are a natural substance from in plants. Flavonoids also have antioxidant properties.
Another component, glycyrrhizin, has been found to have anti-inflammatory and antimicrobial benefits. This may make licorice root extract effective at treating acne. However, more research is needed to support this.
Liquiritin is one of the flavone compounds found in licorice. It has been found to help lighten skin by preventing tyrosinase from reacting with tyrosine. When the two react, protein is converted to melanin. Melanin is the substance in your body that gives your features pigmentation.
Licorice root is native to Southern Europe and Asia. It has been used in traditional Chinese medicine to help with respiratory issues.
Ethylhexylglycerin is created from glycerin. It is a multitasker ingredient that:
The CIR Expert Panel found minimal skin absorption or sensitization of any kind in a safety assessment. Though this ingredient is considered well-tolerated, a small number of cases of allergic dermatitis have been published since 2002. Just be sure to patch test if you are unsure.
Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations.
Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Melia Azadirachta Flower Extract is from the Neem tree. Neem trees originate from India.
Melia Azadirachta Flower Extract contains antioxidants. Antioxidants help fight free-radicals. Free-radicals are molecules that may damage your skin cells, such as pollution.
The flowers of this tree are lilac colored.
This ingredient is also known as neem leaf extract. It contains natural compounds like nimbidin, quercetin, and other polyphenols that give it antibacterial, antifungal, and anti-inflammatory activity.
Lab studies have shown neem leaf extract can inhibit acne-related bacteria and help calm skin. Animal studies on wound gels using 1-3% neem leaf extract found it sped up healing without causing irritation.
A wound-healing study testing gels with the extract at 1%, 2%, and 3% concentrations and found none of them irritated the skin.
Most commercial products also use it in a similar low range (typically under 5%).
Allergy-wise, there are some case reports on neem oil causing allergic contact dermatitis so people with plant/botanical sensitivities may want to patch test first.
Panthenol is a common ingredient that helps hydrate and soothe the skin. It is found naturally in our skin and hair.
There are two forms of panthenol: D and L.
D-panthenol is also known as dexpanthenol. Most cosmetics use dexpanthenol or a mixture of D and L-panthenol.
Panthenol is famous due to its ability to go deeper into the skin's layers. Using this ingredient has numerous pros (and no cons):
Like hyaluronic acid, panthenol is a humectant. Humectants are able to bind and hold large amounts of water to keep skin hydrated.
This ingredient works well for wound healing. It works by increasing tissue in the wound and helps close open wounds.
Once oxidized, panthenol converts to pantothenic acid. Panthothenic acid is found in all living cells.
This ingredient is also referred to as pro-vitamin B5.
Sodium Hyaluronate is the salt form of hyaluronic acid. It is a long sugar chain that is naturally found in your skin, joints, and connective tissue that maintains hydration and elasticity.
In skincare, it works as a humectant. It pulls water from the environment and deeper layers of skin and binds it to the surface.
Interestingly, the size of the molecule affects its behavior:
Some clinical evidence links low molecular weight versions to improved wrinkle depth, elasticity, anti-inflammatory effects, and barrier repair.
Many serums use a blend of both weights so you can get surface hydration plus longer-lasting and deeper effects.
You'll typically see concentrations between 0.1-2% for this ingredient.
Tromethamine (aka THAM) is a synthetic amino acid that shows up in skincare as a helper ingredient.
It functions as a pH adjuster to help neutralize acidic ingredients and set a formula's pH to the right spot.
This matters a lot because a lot of actives (like vitamin C) needs a specific pH to work well and feel comfortable on skin.
Concentration use ranges from 0.1-1.0% depending on the formula.
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!