Skin science article
Beauty of Joseon Dynasty Cream (Old Formulation) Versus Dear, Klairs Rich Moist Soothing Cream
Beauty of Joseon Dynasty Cream (Old Formulation) Versus Dear, Klairs Rich Moist Soothing Cream This barrier-repair moisturizer is formulated around Niacinamide and Adenosine to strengthen the skin barrier and hydrate skin. This calming moisturizer is formulate
Beauty of Joseon Dynasty Cream (Old Formulation) Versus Dear, Klairs Rich Moist Soothing Cream
This barrier-repair moisturizer is formulated around Niacinamide and Adenosine to strengthen the skin barrier and hydrate skin.
This calming moisturizer is formulated around Butyrospermum Parkii Butter and Simmondsia Chinensis Seed Oil to calm redness and hydrate skin.
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Glycerin
Butylene Glycol
Niacinamide
Dipentaerythrityl Hexa C5-9 Acid Esters
Sodium Hyaluronate
Xanthan Gum
Cyclopentasiloxane
Cyclohexasiloxane
Polyacrylate-13
Polyisobutene
Polysorbate 20
Hydrogenated Lecithin
C14-28 Alkyl Acid
Stearyl Alcohol
Behenyl Alcohol
Dimethicone/Vinyl Dimethicone Crosspolymer
Dimethicone
Adenosine
Glyceryl Stearate Se
Cetearyl Alcohol
Polyglyceryl-3 Methylglucose Distearate
Cetyl PEG/PPG-10/1 Dimethicone
Stearic Acid
Tocopheryl Acetate
Sodium Polyacrylate
Olea Europaea Fruit Oil
Helianthus Annuus Seed Oil
Centella Asiatica Extract
Hippophae Rhamnoides Oil
Argania Spinosa Kernel Oil
Butyrospermum Parkii Butter
Ceramide NP
Trehalose
Calendula Officinalis Flower Extract
Caprylhydroxamic Acid
1,2-Hexanediol
Raphanus Sativus Leaf Extract
Oryza Sativa Bran Extract
Cucurbitaceae Extract
Orchid Extract
Honey Extract
Panax Ginseng Root Extract
Carthamus Tinctorius Seed Oil
Phytosphingosine
Ceteareth-20
Glyceryl Citrate/Lactate/Linoleate/Oleate
Parfum
Water, Glycerin, Butylene Glycol, Niacinamide, Dipentaerythrityl Hexa C5-9 Acid Esters, Sodium Hyaluronate, Xanthan Gum, Cyclopentasiloxane, Cyclohexasiloxane, Polyacrylate-13, Polyisobutene, Polysorbate 20, Hydrogenated Lecithin, C14-28 Alkyl Acid, Stearyl Alcohol, Behenyl Alcohol, Dimethicone/Vinyl Dimethicone Crosspolymer, Dimethicone, Adenosine, Glyceryl Stearate Se, Cetearyl Alcohol, Polyglyceryl-3 Methylglucose Distearate, Cetyl PEG/PPG-10/1 Dimethicone, Stearic Acid, Tocopheryl Acetate, Sodium Polyacrylate, Olea Europaea Fruit Oil, Helianthus Annuus Seed Oil, Centella Asiatica Extract, Hippophae Rhamnoides Oil, Argania Spinosa Kernel Oil, Butyrospermum Parkii Butter, Ceramide NP, Trehalose, Calendula Officinalis Flower Extract, Caprylhydroxamic Acid, 1,2-Hexanediol, Raphanus Sativus Leaf Extract, Oryza Sativa Bran Extract, Cucurbitaceae Extract, Orchid Extract, Honey Extract, Panax Ginseng Root Extract, Carthamus Tinctorius Seed Oil, Phytosphingosine, Ceteareth-20, Glyceryl Citrate/Lactate/Linoleate/Oleate, Parfum
Caprylic/Capric Triglyceride
Cetyl Alcohol
Glyceryl Stearate
Cetyl Ethylhexanoate
Simmondsia Chinensis Seed Oil
Sorbitan Sesquioleate
Microcrystalline Wax
Betaine
Sorbitan Stearate
PEG-100 Stearate
Arginine
Carbomer
Chlorphenesin
Paeonia Suffruticosa Root Extract
Illicium Verum Fruit Extract
Nelumbium Speciosum Flower Extract
Citrus Paradisi Fruit Extract
Scutellaria Baicalensis Root Extract
Citric Acid
Beta-Glucan
Portulaca Oleracea Extract
Aloe Barbadensis Leaf Extract
Althaea Rosea Flower Extract
Disodium EDTA
Polyquaternium-51
Apium Graveolens Extract
Brassica Rapa Leaf Extract
Brassica Oleracea Capitata Leaf Extract
Disodium Adenosine Triphosphate
Daucus Carota Sativa Root Extract
Brassica Oleracea Italica Extract
Solanum Lycopersicum Fruit/Leaf/Stem Extract
Lysine Hcl
Sodium Ascorbyl Phosphate
Acetyl Methionine
Theanine
Proline
Palmitic Acid
Arachidic Acid
Oleic Acid
Sodium Hydroxide
Algin
Carica Papaya Fruit Extract
Natto Gum
Citrus Limon Peel Oil
Lavandula Angustifolia Oil
Citrus Aurantium Dulcis Peel Oil
Pelargonium Graveolens Flower Oil
Cananga Odorata Flower Oil
Eucalyptus Globulus Leaf Oil
Water, Glycerin, Caprylic/Capric Triglyceride, Cyclopentasiloxane, Cetyl Alcohol, Glyceryl Stearate, Cetyl Ethylhexanoate, Butyrospermum Parkii Butter, Simmondsia Chinensis Seed Oil, Stearic Acid, Butylene Glycol, Sorbitan Sesquioleate, Microcrystalline Wax, Betaine, Sorbitan Stearate, PEG-100 Stearate, Dimethicone, Arginine, Carbomer, Chlorphenesin, Tocopheryl Acetate, Paeonia Suffruticosa Root Extract, Illicium Verum Fruit Extract, Nelumbium Speciosum Flower Extract, Citrus Paradisi Fruit Extract, Scutellaria Baicalensis Root Extract, Citric Acid, Beta-Glucan, Hydrogenated Lecithin, Portulaca Oleracea Extract, 1,2-Hexanediol, Centella Asiatica Extract, Aloe Barbadensis Leaf Extract, Althaea Rosea Flower Extract, Sodium Hyaluronate, Ceramide NP, Disodium EDTA, Polyquaternium-51, Apium Graveolens Extract, Brassica Rapa Leaf Extract, Oryza Sativa Bran Extract, Brassica Oleracea Capitata Leaf Extract, Disodium Adenosine Triphosphate, Daucus Carota Sativa Root Extract, Brassica Oleracea Italica Extract, Solanum Lycopersicum Fruit/Leaf/Stem Extract, Lysine Hcl, Sodium Ascorbyl Phosphate, Acetyl Methionine, Theanine, Proline, Palmitic Acid, Arachidic Acid, Oleic Acid, Sodium Hydroxide, Algin, Carica Papaya Fruit Extract, Natto Gum, Citrus Limon Peel Oil, Lavandula Angustifolia Oil, Citrus Aurantium Dulcis Peel Oil, Pelargonium Graveolens Flower Oil, Cananga Odorata Flower Oil, Eucalyptus Globulus Leaf Oil
Reviews
Be the first to review
Alternatives
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
1,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse.
It is a:
Humectant, drawing moisture into the skin
Emollient, helping to soften skin
Solvent, dispersing and stabilizing formulas
Preservative booster, enhancing the antimicrobial activity of other preservatives
Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:
Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.
Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.
This ingredient is also known as shea butter. It is a plant-derived extract from the nuts of the Africa shea tree and one of the most well-studied emollients.
Because it has a high concentration of fatty acids (primarily oleic, stearic, and linoleic) it is able to form a protective barrier on the skin's surface. This helps seal in moisture and prevents transepidermal water loss (TEWL).
In vitro research found an increase in skin hydration by 58% and a decrease in TEWL by 37.8% after 24 hours of applying this ingredient (pretty impressive for a single ingredient!).
Besides hydration, shea butter also contains triterpenes that have anti-inflammatory potential. In particule, lupeol cinnamate has shown the highest anti-inflammatory activity in vivo.
Shea butter also contains vitamins A and E which may contribute to antioxidant activity.
While Shea Butter has an SPF rating of about 3-4, it is not a sunscreen replacement.
This ingredient may not be fungal acne safe because its fatty acids fall within the C11-C24 range that the Malassezia yeast can metabolize.
Centella Asiatica Extract (Centella) is one of the most researched botanical extracts in skincare with decades of studies backing its effects on inflammation, collagen, and the skin barrier.
That research keeps pointing back to the same four triterpenoid saponins: Asiaticoside, Madecassoside, Asiatic Acid, and Madecassic Acid.
These compounds allow centella to dial back inflammation, encourage the skin to build and hold onto collagen, support the barrier and hydration, and bring solid antioxidant activity to protect against signs of aging.
Centella also carries a nice supporting cast of Vitamin A, vitamin C, several B vitamins, and amino acids. Put it all together and you get an ingredient that soothes, hydrates, and protects, all at once.
Most of centella's magic comes from the four big compounds (Asiaticoside, Madecassoside, Asiatic Acid, and Madecassic Acid). These are the actives doing the heavy lifting in almost every centella study.
Here is the short version of what they do in the skin:
So it is not just soothing for the sake of soothing. Centella calms the skin AND helps it rebuild.
Just FYI, not all centella on an ingredient list is the same. What you are getting actually depends on the extract:
Fun fact on the ratios: the leaves tend to be richest in Madecassoside and Asiaticoside, and lower in the two acids. The exact amounts shift with where the plant is grown and how it is processed. This means purity really does vary brand to brand.
Centella is one of the most easygoing actives out there.
It layers well with basically everything: niacinamide, hyaluronic acid, peptides, and vitamin C, and also pairs nicely with stronger actives like retinoids and exfoliating acids where it can help take the edge off irritation.
On the safety side, centella and its triterpenes are classified as weak sensitizers, meaning allergic reactions are possible but uncommon.
Patch tests at 1% and 5% came back negative in test panels, and creams at typical use levels did not cause allergic reactions across large groups of people.
But as with any new active, a patch test is still a smart move for very reactive skin.
Centella is widely used because it is effective at low percentages. For context, human safety testing found no meaningful irritation from creams containing centella extract at everyday use levels (the tested amounts were well under 1%).
The irritancy threshold in animal testing was also above 30% (so real-world formulas sit far below anything concerning).
In collagen lab studies, higher concentrations drove more collagen synthesis, so serums built around centella tend to feature it more prominently.
Bottom line: you will find centella working nicely anywhere from a fraction of a percent up to hero-ingredient levels depending on whether it is a supporting soother or the main event.
Fun fact: Centella has been used as a medicine and in food for many centuries. As a medicine, it is used to treat burns, scratches, and wounds.
Ceramide NP (formerly known as Ceramide 3) is one of the skin's naturally occurring lipids.
Since ceramides are the major lipid components of the skin, they are crucial for maintaining skin barrier and hydration. Ceramide NP most closely mirrors the dominant kind in human skin amongst ceramide subtypes.
This ceramide works by slotting into gaps within the stratum corneum's lipid matrix to limit trans-epidermal water loss (TEWL) and shield the skin against external irritants.
A study with 312 patients found that using a ceramide-containing routine for 4 weeks reduced the severity of atopic dermatitis by over 61%.
Another clinical study in subjects aged 60 and older found that a ceramide body wash and moisturizer improved skin dryness and itchy skin in 15 days.
Overall, ceramides are considered non-irritating and safety tests have found little to no observable adverse effects from using this ingredient.
Ceramide NP is usually sourced from plants (like soybean or rice bran), or produced synthetically.
Cyclopentasiloxane (D5) is a lightweight silicone that mostly acts as an emollient and solvent in cosmetics. Its the reason your products feel silky, fast-spreading, and non-greasy.
Since D5 is volatile, it does its thing and then evaporates off the skin quickly.
The safety profile of this ingredient is reassuring; the US CIR Expert Panel concluded D5 is safe as used in cosmetics and Health Canada concluded that D5 is not harmful to human health or the environment as currently used in cosmetics
There's a study that people mention about D5 in a rat study showing tumors. This study is related to long-term inhalation of high D5 levels.
Regulatory bodies have judged this study to be not applicable in topical skincare since skin absorption of D5 is very low and we're not really inhaling huge amounts of D5.
The only restriction for this ingredient is environmental. The European Chemicals Agency (ECHA) restricted D5 in wash-off cosmetics at or above 0.1% due to their persistence in water.
Dimethicone is a type of synthetic silicone created from natural materials such as quartz. It is also known as polydimethylsiloxane.
What it does:
Dimethicone comes in different viscosities:
Depending on the viscosity, dimethicone has different properties.
Ingredients lists don't always show which type is used, so we recommend reaching out to the brand if you have questions about the viscosity.
This ingredient is unlikely to cause irritation because it does not get absorbed into skin. However, people with silicone allergies should be careful about using this ingredient.
Note: Dimethicone may contribute to pilling. This is because it is not oil or water soluble, so pilling may occur when layered with products. When mixed with heavy oils in a formula, the outcome is also quite greasy.
Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Hydrogenated Lecithin is a more stable version of lecithin.
It's made by taking lecithin (a phospholipid commonly found in soybeans and egg yolks) and hydrogenating it. This just means the unsaturated fatty acids are turned into saturated ones so they don't go bad as easily.
This ingredient is an emollient, emulsifier, and penetration enhancer. As an emollient, it helps soften and hydrate skin by trapping moisture within. As an emulsifier, it prevents oil and water ingredients from separating.
Hydrogenated Lecithin can form tiny spherical structures made of phospholipid bilayers called liposomes. These liposomes are able to capture compounds inside their structure and deliver them through the skin barrier.
Because phospholipids are a natural component of our cell membranes, this ingredient is inherently compatible with skin.
A 2021 study found lecithin-based surfactants were less harsh and more tolerable comared to Sodium Lauryl Sulfate (SLS).
Oryza Sativa Bran Extract comes from the outer layer of a rice kernel. It is a byproduct of milling rice, or the operation to produce a whole grain rice product.
This ingredient has moisturizing properties due to its components of polysaccharides and omega-3 fatty acids. It also contains calcium, selenium, phosphorus, iron, and zinc.
Oryza Sativa Bran Extract contains numerous antioxidants such as ferulic acid. Antioxidants help fight free-radical molecules. Free-radical molecules are capable of damaging our cells and other genetic material.
Sodium Hyaluronate is the salt form of hyaluronic acid. It is a long sugar chain that is naturally found in your skin, joints, and connective tissue that maintains hydration and elasticity.
In skincare, it works as a humectant. It pulls water from the environment and deeper layers of skin and binds it to the surface.
Interestingly, the size of the molecule affects its behavior:
Some clinical evidence links low molecular weight versions to improved wrinkle depth, elasticity, anti-inflammatory effects, and barrier repair.
Many serums use a blend of both weights so you can get surface hydration plus longer-lasting and deeper effects.
You'll typically see concentrations between 0.1-2% for this ingredient.
Stearic Acid is a fatty acid that is already found in your skin. It's one of the free fatty acids that works alongside ceramides and cholesterols to maintain your barrier.
In cosmetics, it is a multitasker:
Safety-wise, the CIR Expert Panel has concluded it to be safe in cosmetics when formulated to be non-irritating and non-sensitizing.
Free stearic acid is a C18 fatty acid that the Malassezia yeast can substrate, so this ingredient may not be fungal acne safe.
Tocopheryl Acetate is a stable, shelf-friendly form of vitamin E.
Formulators love it because plain vitamin E oxidizes quickly once it hits air. This acetate version stays stable and resists going off, helping to extend a product's shelf life.
It's actually inactive on its own and works like a slow-release "storage" form; the enzymes in your skin called esterases gradually convert it into active vitamin E over time.
One in vivo study showed 5% of the acetate in the living layer of the epidermis converted to vitamin E after 5 days of application. This study also found the skin gained protection against UV damage even though the conversion was slow and small.
Once converted, vitamin E acts as a skin's main fat-soluble antioxidant that fights free radicals to protect skin from damage.
Topical vitamin E generally boosts the skin's photoprotection, and it reduced UV-damage in animal models.
This ingredient has some brightening potential but it's more of a prevention ingredient than spot-fader. Cell studies show it can slow down melanin production but it's worth noting that it's not the most powerful brightener out there.
Overall, it has a pretty solid safety profile and has been found to be non-irritating and non-comedogenic. Allergic reactions may happen but stay rare due to how widely the ingredient gets used.
The concentration will vary depending on the formula; industry data shows 0.1% in baby lotions, 3% in lipsticks, and 5% in foot powders. You can also find this ingredient at 100% in a pure vitamin E oil.
Most leave-on skincare keeps it at the lower end, often between 0.5-1%.
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!