Skin science article
Beauty of Joseon Light On Serum : Centella + Vita C Versus Dear, Klairs Freshly Juiced Vitamin Charging Serum
Beauty of Joseon Light On Serum : Centella + Vita C Versus Dear, Klairs Freshly Juiced Vitamin Charging Serum This brightening serum is formulated around Centella Asiatica Extract and 3-O-Ethyl Ascorbic Acid to brighten dull-looking skin and calm redness. This
Beauty of Joseon Light On Serum : Centella + Vita C Versus Dear, Klairs Freshly Juiced Vitamin Charging Serum
This brightening serum is formulated around Centella Asiatica Extract and 3-O-Ethyl Ascorbic Acid to brighten dull-looking skin and calm redness.
This brightening serum is formulated around 3-O-Ethyl Ascorbic Acid and Niacinamide to brighten dull-looking skin and fade the look of dark spots.
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Centella Asiatica Extract
3-O-Ethyl Ascorbic Acid
Glycerin
Propanediol
Betaine
Dicaprylyl Carbonate
Methyl Trimethicone
Cetyl Ethylhexanoate
Panthenol
Laminaria Japonica Extract
Eclipta Prostrata Leaf Extract
Phellodendron Amurense Bark Extract
Citrus Unshiu Peel Extract
Brassica Oleracea Acephala Leaf Extract
Hydrolyzed Gardenia Florida Extract
Hydrogenated Lecithin
Cetearyl Alcohol
Water
Dimethicone/Vinyl Dimethicone Crosspolymer
Silica
Bisabolol
Potassium Cetyl Phosphate
Hydrolyzed Jojoba Esters
Cetearyl Olivate
Sorbitan Olivate
Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer
Ammonium Acryloyldimethyltaurate/Beheneth-25 Methacrylate Crosspolymer
Xanthan Gum
Polyglyceryl-10 Myristate
Adenosine
Fructooligosaccharides
Beta-Glucan
Butylene Glycol
Sorbitan Isostearate
Hydrolyzed Hyaluronic Acid
Maltodextrin
Arginine
Carbomer
Ascorbic Acid Polypeptide
1,2-Hexanediol
Hydroxyacetophenone
Ethylhexylglycerin
Centella Asiatica Extract, 3-O-Ethyl Ascorbic Acid, Glycerin, Propanediol, Betaine, Dicaprylyl Carbonate, Methyl Trimethicone, Cetyl Ethylhexanoate, Panthenol, Laminaria Japonica Extract, Eclipta Prostrata Leaf Extract, Phellodendron Amurense Bark Extract, Citrus Unshiu Peel Extract, Brassica Oleracea Acephala Leaf Extract, Hydrolyzed Gardenia Florida Extract, Hydrogenated Lecithin, Cetearyl Alcohol, Water, Dimethicone/Vinyl Dimethicone Crosspolymer, Silica, Bisabolol, Potassium Cetyl Phosphate, Hydrolyzed Jojoba Esters, Cetearyl Olivate, Sorbitan Olivate, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Ammonium Acryloyldimethyltaurate/Beheneth-25 Methacrylate Crosspolymer, Xanthan Gum, Polyglyceryl-10 Myristate, Adenosine, Fructooligosaccharides, Beta-Glucan, Butylene Glycol, Sorbitan Isostearate, Hydrolyzed Hyaluronic Acid, Maltodextrin, Arginine, Carbomer, Ascorbic Acid Polypeptide, 1,2-Hexanediol, Hydroxyacetophenone, Ethylhexylglycerin
Niacinamide
Methylpropanediol
Sodium Hyaluronate
Citrus Limon Fruit Extract
Citrus Nobilis Peel Extract
Citrus Paradisi Fruit Extract
Sodium Polyacryloyldimethyl Taurate
Pentylene Glycol
Dipotassium Glycyrrhizate
Tromethamine
Madecassoside
Sodium Phytate
Tocopherol
Linolenic Acid
Water, 3-O-Ethyl Ascorbic Acid, Butylene Glycol, Niacinamide, 1,2-Hexanediol, Glycerin, Methylpropanediol, Sodium Hyaluronate, Citrus Limon Fruit Extract, Citrus Nobilis Peel Extract, Citrus Paradisi Fruit Extract, Sodium Polyacryloyldimethyl Taurate, Panthenol, Pentylene Glycol, Ethylhexylglycerin, Dipotassium Glycyrrhizate, Tromethamine, Adenosine, Madecassoside, Sodium Phytate, Beta-Glucan, Tocopherol, Linolenic Acid, Xanthan Gum, Carbomer
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Alternatives
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
1,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse.
It is a:
Humectant, drawing moisture into the skin
Emollient, helping to soften skin
Solvent, dispersing and stabilizing formulas
Preservative booster, enhancing the antimicrobial activity of other preservatives
3-O-Ethyl Ascorbic Acid is one of the most popular "stable" vitamin C derivatives in skincare.
Plain ascorbic acid is fantastic but notoriously fragile; it browns, oxidizes, and loses potency fast. So attaching an ethyl group to the third carbon of the molecule gives it some cool perks:
In a formula, it does the 3 classic vitamin C jobs: it acts as an antioxidant, helps brighten skin tone by inhibiting tyrosinase, and supports collagen.
The evidence is reasonably solid for a cosmetic ingredient; Liao and colleagues (2018) showed it's significantly more stable than ascorbic acid while still being effective.
A 2021 study by Zerbinati and colleagues tested a serum with 30% 3-O-ethyl-l-ascorbic acid and 1% lactic acid significantly increased collagen production, reduced UVB-induced DNA damage, and decreased melanin on a reconstructed pigmented skin model.
Typical real world usage sits around 0.5-5% (and 1-2% is common for daily serums).
Amounts up to 30% have been shown to be non-irritating on human skin samples, but two isolated cases reported allergic contact dermatitis so a patch test is sensible if you have reactive skin.
Adenosine is a purine nucleoside that your body already makes in every cell. In skincare, it acts mainly as a skin conditioning and anti-aging agent.
The way it works is fairly well mapped out:
Your skin has cells called fibroblasts that build collagen (the stuff that keeps skin firm and smooth). Adenosine basically flips a switch on these cells that tells them to get to work making more collagen and other proteins. These cells slow down on their own as skin ages, so Adenosine helps give them a little nudge to keep going.
The clinical backing is pretty solid too.
A blind, randomized, placebo-controlled trial of 126 women aged 45-65 tested a 0.1% cream twice daily and found real improvements in crow's feet and frown lines using a precise 3D skin-mapping technique; these changes showed up by week 3 and held at 2 months.
A later study using Adenosine-loaded dissolving microneedle patches reported gains in wrinkle depth, dermal density, elasticity, and hydration.
On concentrations, South Korea's Ministry of Food and Drug Safety has set 0.04% as the approved functional anti-wrinkle level. You'll typically see this ingredient used somewhere in the 0.04-0.1% range since it works at low doses.
This ingredient has been found safe for cosmetics with the data showing no irritation or sensitization.
Overall, this is a great ingredient for any anti-aging routine and has no photosensitizing effect, so it suits both AM and PM use.
Beta-Glucan is a soluble polysaccharide (a chain of glucose sugars) sourced from the cells walls of oats, baker's yeast, mushrooms, and seaweed.
It's a rare ingredient that pulls double-duty as a heavy-duty hydrator and skin-soothing repair agent.
On the surface, it acts as a humectant that holds water in place and reduces moisture loss for a plumper, smoother feel, while its anti-inflammatory and antioxidant properties make it a great pick for calming redness or sensitive skin
The more interesting story is underneath:
Despite its large molecular size, oat beta-glucan has been shown to penetrate the epidermis and reach the dermis by slipping between skin cells. Here, it interacts with fibroblasts and macrophages to nudge collagen synthesis and support wound repair.
A small 2005 split-face clinical study of 27 subjects found topical beta-glucan produced measurable reductions in wrinkle depth, height, and roughness after 8 weeks of use.
It is worth noting the trial was small and the penetration testing used frozen, irradiated skin so the anti-aging data is encouraging rather than definitive.
This ingredient gets along with pretty much everything and is typically used around 0.1-1%.
Fungal acne: This ingredient is not a food source for the Malassezia yeast because it is a glucose polysaccharide with no fatty acid or ester component.
Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:
Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.
Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.
Carbomer is a synthetic thickening and gelling agent. It's basically the ingredient that gives a lot of serums, gels, creams, and sunscreens their smooth, non-sticky texture.
Although legally permitted at very high levels, carbomers are normally used at concentrations below 1%.
It also needs to be neutralized to actually thicken, and because it is a large molecule, it doesn't really penetrate the skin barrier.
Allergy-wise, the risk is very low. Clinical studies show carbomers have low potential for skin irritation/sensitization even at concentrations up to 100%.
A 2024 UK study patch-tested 1,302 patients and found true allergy to the parent group of carbomer to be rare with no confirmed relevant reactions.
Ethylhexylglycerin is created from glycerin. It is a multitasker ingredient that:
The CIR Expert Panel found minimal skin absorption or sensitization of any kind in a safety assessment. Though this ingredient is considered well-tolerated, a small number of cases of allergic dermatitis have been published since 2002. Just be sure to patch test if you are unsure.
Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations.
Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Panthenol is a common ingredient that helps hydrate and soothe the skin. It is found naturally in our skin and hair.
There are two forms of panthenol: D and L.
D-panthenol is also known as dexpanthenol. Most cosmetics use dexpanthenol or a mixture of D and L-panthenol.
Panthenol is famous due to its ability to go deeper into the skin's layers. Using this ingredient has numerous pros (and no cons):
Like hyaluronic acid, panthenol is a humectant. Humectants are able to bind and hold large amounts of water to keep skin hydrated.
This ingredient works well for wound healing. It works by increasing tissue in the wound and helps close open wounds.
Once oxidized, panthenol converts to pantothenic acid. Panthothenic acid is found in all living cells.
This ingredient is also referred to as pro-vitamin B5.
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!
Xanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.
On the technical side of things, xanthan gum is a polysaccharide - a combination consisting of multiple sugar molecules bonded together.
Xanthan gum is a pretty common and great ingredient. It is a natural, non-toxic, non-irritating ingredient that is also commonly used in food products.