Skin science article
Belif Moisturizing Eye Bomb Versus Biossance Squalane + Peptide Eye Gel
Belif Moisturizing Eye Bomb Versus Biossance Squalane + Peptide Eye Gel This anti-aging eye moisturizer is formulated around Squalane and Panthenol to soften the look of wrinkles and hydrate skin. This anti-aging eye moisturizer is formulated around Squalane a
Belif Moisturizing Eye Bomb Versus Biossance Squalane + Peptide Eye Gel
This anti-aging eye moisturizer is formulated around Squalane and Panthenol to soften the look of wrinkles and hydrate skin.
This anti-aging eye moisturizer is formulated around Squalane and Niacinamide to soften the look of wrinkles and hydrate skin.
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Dipropylene Glycol
Butylene Glycol
Glycerin
Squalane
Cyclopentasiloxane
Caprylyl Trimethicone
Dimethicone
Hdi/Trimethylol Hexyllactone Crosspolymer
1,2-Hexanediol
Sucrose Polystearate
Glyceryl Stearate
Panthenol
PCA Dimethicone
Triethylhexanoin
Dimethicone/Vinyl Dimethicone Crosspolymer
PEG-100 Stearate
C14-22 Alcohols
Silica
Ceramide NP
Hydrogenated Lecithin
Cedrol
Hydrogenated Polyisobutene
Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer
PEG-10 Rapeseed Sterol
Carbomer
C12-20 Alkyl Glucoside
Tromethamine
Polysorbate 60
Glycereth-20
Cellulose
Trisodium EDTA
Sorbitan Isostearate
Bakuchiol
Caffeine
Centella Asiatica Leaf Extract
Calendula Officinalis Flower Extract
Avena Sativa Kernel Extract
Nepeta Cataria Extract
Rubus Idaeus Leaf Extract
Baptisia Tinctoria Root Extract
Stellaria Media Extract
Alchemilla Vulgaris Leaf Extract
Althaea Officinalis Root Extract
Rosa Damascena Flower Extract
Spiraea Ulmaria Flower Extract
Viola Tricolor Extract
Achillea Millefolium Flower Extract
Symphytum Officinale Leaf Extract
Trifolium Pratense Flower Extract
Menyanthes Trifoliata Leaf Extract
Salix Alba Bark Extract
Sodium Lactate
Polysorbate 20
Caprylyl Glycol
Palmitoyl Tripeptide-1
Acetyl Hexapeptide-8
Palmitoyl Tetrapeptide-7
Citrus Aurantium Dulcis Peel Oil
Citrus Aurantifolia Oil
Pelargonium Graveolens Flower Oil
Rosmarinus Officinalis Leaf Oil
Limonene
Citronellol
Geraniol
Citral
Linalool
Water, Dipropylene Glycol, Butylene Glycol, Glycerin, Squalane, Cyclopentasiloxane, Caprylyl Trimethicone, Dimethicone, Hdi/Trimethylol Hexyllactone Crosspolymer, 1,2-Hexanediol, Sucrose Polystearate, Glyceryl Stearate, Panthenol, PCA Dimethicone, Triethylhexanoin, Dimethicone/Vinyl Dimethicone Crosspolymer, PEG-100 Stearate, C14-22 Alcohols, Silica, Ceramide NP, Hydrogenated Lecithin, Cedrol, Hydrogenated Polyisobutene, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, PEG-10 Rapeseed Sterol, Carbomer, C12-20 Alkyl Glucoside, Tromethamine, Polysorbate 60, Glycereth-20, Cellulose, Trisodium EDTA, Sorbitan Isostearate, Bakuchiol, Caffeine, Centella Asiatica Leaf Extract, Calendula Officinalis Flower Extract, Avena Sativa Kernel Extract, Nepeta Cataria Extract, Rubus Idaeus Leaf Extract, Baptisia Tinctoria Root Extract, Stellaria Media Extract, Alchemilla Vulgaris Leaf Extract, Althaea Officinalis Root Extract, Rosa Damascena Flower Extract, Spiraea Ulmaria Flower Extract, Viola Tricolor Extract, Achillea Millefolium Flower Extract, Symphytum Officinale Leaf Extract, Trifolium Pratense Flower Extract, Menyanthes Trifoliata Leaf Extract, Salix Alba Bark Extract, Sodium Lactate, Polysorbate 20, Caprylyl Glycol, Palmitoyl Tripeptide-1, Acetyl Hexapeptide-8, Palmitoyl Tetrapeptide-7, Citrus Aurantium Dulcis Peel Oil, Citrus Aurantifolia Oil, Pelargonium Graveolens Flower Oil, Rosmarinus Officinalis Leaf Oil, Limonene, Citronellol, Geraniol, Citral, Linalool
Aloe Barbadensis Leaf Juice
Niacinamide
Chondrus Crispus Extract
Malus Domestica Fruit Cell Culture Extract
Acetyl Tetrapeptide-5
Tocopherol
Pentylene Glycol
Cucumis Sativus Fruit Extract
Tetrahexyldecyl Ascorbate
Camellia Sinensis Leaf Extract
Lycium Barbarum Fruit Extract
Lycopene
Vitis Vinifera Skin Extract
Sodium Hyaluronate
Acacia Senegal Gum
Dimethicone Crosspolymer
Xanthan Gum
Ethyl Lauroyl Arginate Hcl
Lecithin
Ammonium Acryloyldimethyltaurate/Vp Copolymer
Phenoxyethanol
Potassium Sorbate
Citric Acid
Water, Aloe Barbadensis Leaf Juice, Squalane, Niacinamide, Glycerin, Panthenol, Chondrus Crispus Extract, Malus Domestica Fruit Cell Culture Extract, Acetyl Tetrapeptide-5, Acetyl Hexapeptide-8, Tocopherol, Pentylene Glycol, Cucumis Sativus Fruit Extract, Tetrahexyldecyl Ascorbate, Camellia Sinensis Leaf Extract, Lycium Barbarum Fruit Extract, Lycopene, Vitis Vinifera Skin Extract, Sodium Hyaluronate, Caffeine, Acacia Senegal Gum, Dimethicone Crosspolymer, Xanthan Gum, Carbomer, Ethyl Lauroyl Arginate Hcl, Lecithin, Ammonium Acryloyldimethyltaurate/Vp Copolymer, Silica, Phenoxyethanol, Potassium Sorbate, Citric Acid, Caprylyl Glycol
Reviews
Alternatives
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Acetyl Hexapeptide-8 (also known as Argireline) is a synthetic hexapeptide that is often called a "topical Botox alternative".
It works by mimicking how Botox relaxes muscles; it interferes with the signaling process that tells your facial muscles to contract. This can help soften expression lines like forehead wrinkles or crow's feet over time.
The comparison to Botox does have limits because the molecule is water-loving and relatively large.
Acetyl Hexapeptide-8 has a hard time absorbing deeply enough through the skin's outer barrier to actually reach the muscles.
So whether it truly works the way Botox does at a biological level is still up for debate, but early clinical outcomes are fairly encouraging.
A 12 week human study of a multi-ingredient regimen containing this ingredient saw:
While some studies have observed improvements in wrinkle appearance, it is important to note that more consistent results are seen in multi-ingredient formulations (vs just Acetyl Hexapeptide-8 alone).
Some research studies also used higher concentrations (up to 10%) while this ingredient is usually found in concentrations up to 0.005% in leave-on formulations.
Caffeine is a naturally occurring plant compound found in coffee beans, tea leaves, cocoa pods, and guarana.
As an antioxidant, caffeine protects your skin from free radical damage caused by UV exposure and envionrmnetal stressors.
Early research also shows that caffeine can help calm redness, soothe irritated skin, and support hair growth by stimulating microcirculation in the scalp.
You might have seen eye creams marketing caffeine as a depuffing ingredient. This is because it is a vasoconstrictor meaning it can temporarily constrict blood vessels, though clinical evidence for this specific use is still limited.
Most skincare products contain this ingredient at concentrations between 1-6%. It is able to penetrate skin easily regardless of skin type or thickness.
Just so you know, a very small number of case reports describe caffeine-induced allergy. This ingredient is generally well-tolerated, non-irritating, and non-sensitizing for the majority of people.
Caprylyl Glycol is a humectant, skin conditioner, emollient, and preservative booster derived from either caprylic acid or synthetically created.
Typical use levels vary from 0.3-1% as a preservative booster and go up to 2% to condition skin.
Because it is not a free-fatty acid, this ingredient is fungal acne safe (there's nothing for Malassezia to feed on).
Carbomer is a synthetic thickening and gelling agent. It's basically the ingredient that gives a lot of serums, gels, creams, and sunscreens their smooth, non-sticky texture.
Although legally permitted at very high levels, carbomers are normally used at concentrations below 1%.
It also needs to be neutralized to actually thicken, and because it is a large molecule, it doesn't really penetrate the skin barrier.
Allergy-wise, the risk is very low. Clinical studies show carbomers have low potential for skin irritation/sensitization even at concentrations up to 100%.
A 2024 UK study patch-tested 1,302 patients and found true allergy to the parent group of carbomer to be rare with no confirmed relevant reactions.
Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Panthenol is a common ingredient that helps hydrate and soothe the skin. It is found naturally in our skin and hair.
There are two forms of panthenol: D and L.
D-panthenol is also known as dexpanthenol. Most cosmetics use dexpanthenol or a mixture of D and L-panthenol.
Panthenol is famous due to its ability to go deeper into the skin's layers. Using this ingredient has numerous pros (and no cons):
Like hyaluronic acid, panthenol is a humectant. Humectants are able to bind and hold large amounts of water to keep skin hydrated.
This ingredient works well for wound healing. It works by increasing tissue in the wound and helps close open wounds.
Once oxidized, panthenol converts to pantothenic acid. Panthothenic acid is found in all living cells.
This ingredient is also referred to as pro-vitamin B5.
Silica, also known as silicon dioxide, is a naturally occurring mineral. It is used as a fine, spherical, and porous powder in cosmetics.
Though it has exfoliant properties, the function of silica varies depending on the product.
The unique structure of silica enhances the spreadability and adds smoothness, making it a great texture enhancer.
It is also used as an active carrier, emulsifier, and mattifier due to its ability to absorb excess oil.
In some products, tiny microneedles called spicules are made from silica or hydrolyzed sponge. When you rub them in, they lightly polish away dead skin layers and enhance the penetration of active ingredients.
Squalane is the hydrogenated and shelf-stable form of squalene (a lipid that naturally occurs in human sebum).
It is an emollient and skin conditioning agent that is able to integrate seamlessly into the skin's lipid barrier without clogging pores.
This is due to how structurally similar it is to what your skin already produces.
Though it is mostly an emollient that helps soften and hydrate skin, it also has some humectant and occlusive action. Humectants help the skin retain moisture while occlusives seal it in, making squalane a triple-threat moisturizer.
Research shows it has antioxidant capabilities that help protect against stressors like UV exposure, specifically UVA induced oxidative stress. This study also found that it supports collagen biosynthesis in human dermal fibroblasts.
No clinical study has reported significant adverse effects and irritation reactions are very rare from this ingredient (even at 100% concentration).
Overall, it's a fantastic ingredient for hydration and is suitable for all skin types.
This depends on the source. Squalane can be derived from both plants and animals. Most squalane used in skincare comes from plants.
Please note: the source of squalane is only known if disclosed by the brand. We recommend reaching out to the brand if you have any questions about their squalane.
Read more about squalene with an "e".
Though squalane is often called an oil, it’s technically not one. It is a hydrocarbon, meaning it is only made of carbon and hydrogen. True oils are triglycerides and made of fatty acids and glycerol.
The term “oil-free” isn’t regulated so companies can define it however they want. Some exclude all oils, while others just avoid mineral oil or comedogenic oils.
Squalane has a comedogenic rating of 1 from the original 1972 study that tested raw ingredients under occlusion on rabbit ears. This system is not standardized or peer-reviewed, and using the raw ingredients is very different from how diluted cosmetic formulations are used on human skin.
A comedogenic rating of 1 means it is "unlikely to clog pores" according to the original rating system.
The overall formula of a product matters more than the individual ingredients on whether or not it will cause clogged pores.
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!