Boots Bakuchiol Face Serum Versus Niod Copper Amino Isolate Serum 2:1 (CAIS2)

Boots Bakuchiol Face Serum Versus Niod Copper Amino Isolate Serum 2:1 (CAIS2)

This anti-aging serum is formulated around Bakuchiol and Bisabolol to soften the look of wrinkles and refine skin texture.

This serum is formulated around Lactococcus Ferment Lysate to support the skin barrier and reduce redness.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Water

Glycerin

Isononyl Isononanoate

PEG-20 Methyl Glucose Sesquistearate

Phenoxyethanol

Bakuchiol

Acrylates/C10-30 Alkyl Acrylate Crosspolymer

Chlorphenesin

Bisabolol

Xanthan Gum

Potassium Hydroxide

Disodium EDTA

Aloe Barbadensis Leaf Juice

Maltodextrin

Potassium Sorbate

Sodium Benzoate

Water, Glycerin, Isononyl Isononanoate, PEG-20 Methyl Glucose Sesquistearate, Phenoxyethanol, Bakuchiol, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Chlorphenesin, Bisabolol, Xanthan Gum, Potassium Hydroxide, Disodium EDTA, Aloe Barbadensis Leaf Juice, Maltodextrin, Potassium Sorbate, Sodium Benzoate

Lactococcus Ferment Lysate

Ethyl Linoleate

Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer

Hexanoyl Dipeptide-3 Norleucine Acetate

Myristoyl Nonapeptide-3

Yeast Extract

Soy Amino Acids

Pseudoalteromonas Exopolysaccharides

Lecithin

Sorbitan Isostearate

Isohexadecane

Polysorbate 60

Polyacrylate Crosspolymer-6

Trisodium Ethylenediamine Disuccinate

Sodium Salicylate

Citric Acid

Sodium Chloride

Pentylene Glycol

Ethoxydiglycol

Water, Lactococcus Ferment Lysate, Glycerin, Ethyl Linoleate, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Hexanoyl Dipeptide-3 Norleucine Acetate, Myristoyl Nonapeptide-3, Yeast Extract, Soy Amino Acids, Bisabolol, Pseudoalteromonas Exopolysaccharides, Lecithin, Sorbitan Isostearate, Isohexadecane, Polysorbate 60, Polyacrylate Crosspolymer-6, Trisodium Ethylenediamine Disuccinate, Sodium Salicylate, Citric Acid, Sodium Chloride, Potassium Sorbate, Sodium Benzoate, Pentylene Glycol, Ethoxydiglycol, Phenoxyethanol, Chlorphenesin

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Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Bisabolol is a gentle skin conditioner, antioxidant, and soothing ingredient.

It's primary claim to fame is soothing and research shows topically applied bisabolol can quiet the chemical messengers that cause your skin to become inflamed, helping to sooth any irritation.

A clinical study found that applying 0.5% bisabolol daily for 8 weeks produced an average 9% decrease in skin pigmentation. Researchers found it can also suppress the process that leads to excess melanin production in skin.

In vitro studies found that bisabolol combined with propylene glycol significantly increased skin permeability by increasing lipid fluidity in the stratum corneum.

You'll likely see use concentrations quite low, usually 0.1-0.2%.

Overall, this is a well-tolerated ingredient that works well in formulas designed for sensitive, reactive, or post-procedure skin.

Chlorphenesin is a synthetic preservative. It helps protect a product against bacteria in order to extend shelf life. In most cases, Chlorphenesin is paired with other preservatives such as phenoxyethanol and caprylyl glycol.

Chlorphenesin is a biocide. This means it is able to help fight the microorganisms on our skin. It is also able to fight odor-releasing bacteria.

Chlorphenesin is soluble in both water and glycerin.

Studies show Chlorphenesin is easily absorbed by our skin. You should speak with a skincare professional if you have concerns about using Chlorphenesin.

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Phenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!).

It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome.

On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive.

Another perk of this ingredient is that it stays functional across a wide pH range (3-10).

You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own.

Typical use concentrations range from 0.3-1% depending on the formula, and this ingredient is capped at 1% int the EU.

Safety-wise, the fear mongering does not hold up to the evidence. The EU's Scientific Committee on Consumer Safety and FDA consider it safe as a preservative at up to 1%, including for children of all ages.

Adverse systemic effects only showed up in animal studies at exposures roughly 200x higher than what people get from cosmetics. And despite its very widespread use, this ingredient is a rare sensitizer and allergic reactions are uncommon.

Potassium Sorbate is a preservative used to prevent yeast and mold in products. It is commonly found in both cosmetic and food products.

This ingredient comes from potassium salt derived from sorbic acid. Sorbic acid is a natural antibiotic and effective against fungus.

Both potassium sorbate and sorbic acid can be found in baked goods, cheeses, dried meats, dried fruit, ice cream, pickles, wine, yogurt, and more.

You'll often find this ingredient used with other preservatives.

Sodium Benzoate is a preservative. It's used in both cosmetic and food products to inhibit the growth of mold and bacteria. It is typically produced synthetically.

Both the US FDA and EU Health Committee have approved the use of sodium benzoate. In the US, levels of 0.1% (of the total product) are allowed.

Sodium benzoate works as a preservative by inhibiting the growth of bacteria inside of cells. It prevents the cell from fermenting a type of sugar using an enzyme called phosphofructokinase.

It is the salt of benzoic acid. Foods containing sodium benzoate include soda, salad dressings, condiments, fruit juices, wines, and snack foods.

Studies for using ascorbic acid and sodium benzoate in cosmetics are lacking, especially in skincare routines with multiple steps.

We always recommend speaking with a professional, such as a dermatologist, if you have any concerns.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

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