Skin science article
CeraVe Daily Moisturizing Lotion for Normal to Dry Skin Versus The Derma Co Skin Renew Barrier Repair Peptide Moisturizer
CeraVe Daily Moisturizing Lotion for Normal to Dry Skin Versus The Derma Co Skin Renew Barrier Repair Peptide Moisturizer This barrier-repair moisturizer is formulated around Ceramide NP and Ceramide AP to strengthen the skin barrier and hydrate skin. This bar
CeraVe Daily Moisturizing Lotion for Normal to Dry Skin Versus The Derma Co Skin Renew Barrier Repair Peptide Moisturizer
This barrier-repair moisturizer is formulated around Ceramide NP and Ceramide AP to strengthen the skin barrier and hydrate skin.
This barrier-repair moisturizer is formulated around Niacinamide and Ceramide NP to strengthen the skin barrier and soften the look of wrinkles.
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Glycerin
Caprylic/Capric Triglyceride
Cetearyl Alcohol
Cetyl Alcohol
Potassium Phosphate
Ceramide NP
Ceramide AP
Ceramide EOP
Carbomer
Dimethicone
Ceteareth-20
Behentrimonium Methosulfate
Methylparaben
Sodium Lauroyl Lactylate
Cholesterol
Disodium EDTA
Dipotassium Phosphate
Propylparaben
Hydrolyzed Hyaluronic Acid
Phytosphingosine
Xanthan Gum
Polysorbate 20
Polyglyceryl-3 Diisostearate
Water, Glycerin, Caprylic/Capric Triglyceride, Cetearyl Alcohol, Cetyl Alcohol, Potassium Phosphate, Ceramide NP, Ceramide AP, Ceramide EOP, Carbomer, Dimethicone, Ceteareth-20, Behentrimonium Methosulfate, Methylparaben, Sodium Lauroyl Lactylate, Cholesterol, Disodium EDTA, Dipotassium Phosphate, Propylparaben, Hydrolyzed Hyaluronic Acid, Phytosphingosine, Xanthan Gum, Polysorbate 20, Polyglyceryl-3 Diisostearate
Propanediol
Coco-Caprylate/Caprate
Niacinamide
Betaine
Cyclopentasiloxane
Neopentyl Glycol Diheptanoate
Isododecane
Squalane
3-O-Ethyl Ascorbic Acid
PEG-7 Glyceryl Cocoate
Phenoxyethanol
Ethylhexylglycerin
Glyceryl Stearate
Palmitoyl Tripeptide-5
Polyacrylate-13
Polyisobutene
Glyceryl Stearate Citrate
Centella Asiatica Extract
Xylitylglucoside
Anhydroxylitol
Xylitol
Sodium Hyaluronate
Allantoin
Acrylates/C10-30 Alkyl Acrylate Crosspolymer
Triethanolamine
Sodium Gluconate
Water, Propanediol, Coco-Caprylate/Caprate, Cetearyl Alcohol, Niacinamide, Betaine, Cyclopentasiloxane, Neopentyl Glycol Diheptanoate, Isododecane, Squalane, 3-O-Ethyl Ascorbic Acid, Ceramide NP, PEG-7 Glyceryl Cocoate, Phenoxyethanol, Ethylhexylglycerin, Glyceryl Stearate, Palmitoyl Tripeptide-5, Polyacrylate-13, Polyisobutene, Polysorbate 20, Glyceryl Stearate Citrate, Centella Asiatica Extract, Xylitylglucoside, Anhydroxylitol, Xylitol, Sodium Hyaluronate, Allantoin, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Triethanolamine, Sodium Gluconate
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Alternatives
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Ceramide NP (formerly known as Ceramide 3) is one of the skin's naturally occurring lipids.
Since ceramides are the major lipid components of the skin, they are crucial for maintaining skin barrier and hydration. Ceramide NP most closely mirrors the dominant kind in human skin amongst ceramide subtypes.
This ceramide works by slotting into gaps within the stratum corneum's lipid matrix to limit trans-epidermal water loss (TEWL) and shield the skin against external irritants.
A study with 312 patients found that using a ceramide-containing routine for 4 weeks reduced the severity of atopic dermatitis by over 61%.
Another clinical study in subjects aged 60 and older found that a ceramide body wash and moisturizer improved skin dryness and itchy skin in 15 days.
Overall, ceramides are considered non-irritating and safety tests have found little to no observable adverse effects from using this ingredient.
Ceramide NP is usually sourced from plants (like soybean or rice bran), or produced synthetically.
Cetearyl alcohol is a waxy mixture of two fatty alcohols: cetyl alcohol and stearyl alcohol. It is an emollient and emulsifier.
Despite having "alcohol" in its name, it has nothing to do with drying solvent alcohols; the FDA also allows "alcohol-free" products to contain fatty alcohols like this ingredient.
It plays several roles in a formula:
Typical use levels for this ingredient sit around 1-10% and the Cosmetic Ingredient Review Expert Panel has affirmed safety at concentrations up to 25% in leave-on products.
Multiple assessments have found it to be non-irritating and non-sensitizing to most people.
However, there have been some cases of allergic contact dermatitis in patients with chronically compromised skin barriers.
Cetearyl alcohol has a comedogenic rating of 2 and irritancy rating of 1. Both of these numbers come from the 1989 study that used rabbit ears; a "2" means mildly comedogenic and a "1" means low irritancy.
Here's the catch: rabbit skin is more sensitive than human skin and throws a lot of false positives. A 1996 reappraisal found that ingredients rated 1-2 in the rabbit ear tests are generally safe for humans.
Remember comedogenic ratings are unable to assess the entire formula of a product or how it will react on your skin. Just be sure to patch test if you are unsure about certain ingredients.
This ingredient is not fungal acne safe. Cetearyl alcohol is a fatty alcohol with chain lengths that fall within the range that Malassezia can metabolize.
A 2019 study has also observed Malassezia growth in the presence of this ingredient, confirming it to be not-fungal acne safe.
Polysorbate 20 is a gentle, water-soluble emulsifier and mild surfactant. It stops oil and water from separating to keep your formulas blended and stable.
It also acts as a mild penetration enhancer by helping active ingredients absorb slightly better.
The common safety discussion around this ingredient involves a manufacturing byproduct called 1,4-dioxane.
Trace amounts can form during production but the EU's Scientific Committee on Consumer Safety has concluded that levels at/below 10 ppm in finished products are safe (commercial products consistently fall within acceptable margins).
True allergic reactions are uncommon and the CIR Expert Panel has confirmed this ingredient to be safe as used in cosmetics.
Because it is derived from lauric acid, it may not be fungal acne safe.
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!