Cetaphil Healthy Renew Purified Peptides Face Serum Versus Allies of Skin Multi Peptides & GF Advanced Lifting Serum

Cetaphil Healthy Renew Purified Peptides Face Serum Versus Allies of Skin Multi Peptides & GF Advanced Lifting Serum

This anti-aging serum is formulated around Panthenol and Niacinamide to soften the look of wrinkles and strengthen the skin barrier.

This anti-aging serum is formulated around Sh-Oligopeptide-1 and Dipeptide Diaminobutyroyl Benzylamide Diacetate to soften the look of wrinkles.

What's inside

Key Ingredients

Benefits

Concerns

No concerns

Ingredients Side-by-side

Water

Butylene Glycol

Glycerin

Panthenol

1,2-Hexanediol

Niacinamide

Cetyl Ethylhexanoate

Hydrogenated Polydecene

Acrylates/C10-30 Alkyl Acrylate Crosspolymer

Tromethamine

Oryza Sativa Lees Extract

Leontopodium Alpinum Extract

Calcium Alginate

Propanediol

Hydrolyzed Soy Flour

Ethylhexylglycerin

Agar

Adenosine

Trisodium Ethylenediamine Disuccinate

Synthetic Fluorphlogopite

Caprylyl Glycol

Iron Oxides

Citric Acid

Sodium Benzoate

Potassium Sorbate

Buddleja Davidii Extract

Thymus Vulgaris Extract

Tocopherol

Water, Butylene Glycol, Glycerin, Panthenol, 1,2-Hexanediol, Niacinamide, Cetyl Ethylhexanoate, Hydrogenated Polydecene, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Tromethamine, Oryza Sativa Lees Extract, Leontopodium Alpinum Extract, Calcium Alginate, Propanediol, Hydrolyzed Soy Flour, Ethylhexylglycerin, Agar, Adenosine, Trisodium Ethylenediamine Disuccinate, Synthetic Fluorphlogopite, Caprylyl Glycol, Iron Oxides, Citric Acid, Sodium Benzoate, Potassium Sorbate, Buddleja Davidii Extract, Thymus Vulgaris Extract, Tocopherol

Heptyl Glucoside

Isodecyl Neopentanoate

Acacia Senegal Gum

Polysorbate 20

Centella Asiatica Leaf Extract

Helianthus Annuus Seed Oil

Phospholipids

Glycolipids

Dimethyl Sulfone

Ornithine

Lecithin

Hydrogenated Lecithin

Copper Lysinate/Prolinate

Methylglucoside Phosphate

Crocus Chrysanthus Bulb Extract

Sh-Oligopeptide-1

Dipeptide Diaminobutyroyl Benzylamide Diacetate

Pentapeptide-18

Pentapeptide-48

Butyrospermum Parkii Butter

Leuconostoc/Radish Root Ferment Filtrate

Caprylic/Capric Triglyceride

C12-15 Alkyl Benzoate

Sclerotium Gum

Xanthan Gum

Levulinic Acid

P-Anisic Acid

Sodium Gluconate

Maltodextrin

Sodium Hydroxide

Heptanol

Phenethyl Alcohol

Phenoxyethanol

Water, Glycerin, Heptyl Glucoside, Isodecyl Neopentanoate, Acacia Senegal Gum, Polysorbate 20, Centella Asiatica Leaf Extract, Helianthus Annuus Seed Oil, Tocopherol, Phospholipids, Glycolipids, Dimethyl Sulfone, Ornithine, Lecithin, Hydrogenated Lecithin, Copper Lysinate/Prolinate, Methylglucoside Phosphate, Crocus Chrysanthus Bulb Extract, Sh-Oligopeptide-1, Dipeptide Diaminobutyroyl Benzylamide Diacetate, Pentapeptide-18, Pentapeptide-48, Butyrospermum Parkii Butter, Leuconostoc/Radish Root Ferment Filtrate, Caprylic/Capric Triglyceride, Ethylhexylglycerin, C12-15 Alkyl Benzoate, Sclerotium Gum, Xanthan Gum, Caprylyl Glycol, Levulinic Acid, P-Anisic Acid, Sodium Gluconate, Propanediol, Maltodextrin, Citric Acid, Sodium Hydroxide, Heptanol, Phenethyl Alcohol, Phenoxyethanol

Reviews

Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Caprylyl Glycol is a humectant, skin conditioner, emollient, and preservative booster derived from either caprylic acid or synthetically created.

Typical use levels vary from 0.3-1% as a preservative booster and go up to 2% to condition skin.

Because it is not a free-fatty acid, this ingredient is fungal acne safe (there's nothing for Malassezia to feed on).

Citric Acid is an alpha hydroxy acid (AHA) naturally found in citrus fruits like oranges, lemons, and limes.

Like other AHAs, citric acid can exfoliate skin by breaking down the bonds that hold dead skin cells together. This helps reveal smoother and brighter skin underneath.

However, this exfoliating effect only happens at high concentrations (20%) which can be hard to find in cosmetic products.

Due to this, citric acid is usually included in small amounts as a pH adjuster. This helps keep products slightly more acidic and compatible with skin's natural pH.

In skincare formulas, citric acid can:

While it can provide some skin benefits, research shows lactic acid and glycolic acid are generally more effective and less irritating exfoliants.

Most citric acid used in skincare today is made by fermenting sugars (usually from molasses). This synthetic version is identical to the natural citrus form but easier to stabilize and use in formulations.

Rosacea skin has a lower threshold for acids generally, with 62.5% of rosacea subjects in one study reacting to lactic acid in a sting test. This is why we mark citric acid as a potential rosacea trigger.

However, this ingredient shows up as a pH adjuster or chelator at roughly 0.1-1% in many products. These low levels are unlikely to be an issue for rosacea skin and becomes a potential trigger at exfoliating concentrations (20%). Because everybody's skin is unique, we recommend a patch test if you are unsure.

Ethylhexylglycerin is created from glycerin. It is a multitasker ingredient that:

The CIR Expert Panel found minimal skin absorption or sensitization of any kind in a safety assessment. Though this ingredient is considered well-tolerated, a small number of cases of allergic dermatitis have been published since 2002. Just be sure to patch test if you are unsure.

Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations.

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Propanediol is an all-star ingredient. It softens, hydrates, and smooths the skin.

It’s often used to:

Propanediol is not likely to cause sensitivity and considered safe to use. It is derived from corn or petroleum with a clear color and no scent.

Tocopherol is a fat-soluble antioxidant known as Vitamin E.

You'll find this ingredient in the vast majority of skincare (for good reason). It works to neutralize free radicals, or unstable molecules generated by UV exposure, pollution, and other environmental stressors, before they can cause oxidative damage to your skin cells.

Topically applied tocopherol has been shown to protect against UV damage by ramping up the skin's own natural defense enzymes.

It also acts as a skin conditioning agent; some studies show that regular topical use can improve the skin's water-binding capacity over 2-4 weeks.

This ingredient is especially loved for being a team player. When combined with Vitamin C, the photoprotective effect of both ingredients roughly doubles and the combo also helps reduce UV-induced DNA damage.

This ingredient has some brightening potential but it's more of a prevention ingredient than spot-fader. Cell studies show it can slow down melanin production but it's worth noting that it's not the most powerful brightener out there.

In formulations, it also serves as a stabilizer that helps protect other oxidation-prone ingredients from degrading.

Concentrations usually range from 0.1-1% in most leave-on products.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

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