Peptide Skincare & BeautySkin science and ingredient guides

Skin science article

Clinique Clinique iD Dramatically Different Hydrating Jelly & Active Cartridge Concentrate for Lines & Wrinkles Versus Olay Regenerist Retinol 24 + Peptide Night Moisturizer

Clinique Clinique iD Dramatically Different Hydrating Jelly & Active Cartridge Concentrate for Lines & Wrinkles Versus Olay Regenerist Retinol 24 + Peptide Night Moisturizer This anti-aging moisturizer is formulated around Acetyl Hexapeptide-8 and Palmitoyl Te

Clinique Clinique iD Dramatically Different Hydrating Jelly & Active Cartridge Concentrate for Lines & Wrinkles Versus Olay Regenerist Retinol 24 + Peptide Night Moisturizer

This anti-aging moisturizer is formulated around Acetyl Hexapeptide-8 and Palmitoyl Tetrapeptide-7 to soften the look of wrinkles.

This anti-aging night moisturizer is formulated around Retinol and Niacinamide to soften the look of wrinkles and refine skin texture.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Water

Bis-PEG-18 Methyl Ether Dimethyl Silane

Butylene Glycol

Glycerin

Cucumis Sativus Fruit Extract

Hypnea Musciformis Extract

Gelidiella Acerosa Extract

Hordeum Vulgare Extract

Padina Pavonica Thallus Extract

Helianthus Annuus Seedcake

Sucrose

Caffeine

Sodium Hyaluronate

Hydroxyethyl Urea

Hydrolyzed Rice Extract

Sorbitol

Sodium Polyaspartate

PPG-6-Decyltetradeceth-30

Ethylhexylglycerin

Propylene Glycol Dicaprate

Caprylyl Glycol

Trehalose

Polysorbate 80

Carbomer

Sodium Hydroxide

Hexylene Glycol

Citric Acid

Sodium Citrate

Disodium EDTA

Phenoxyethanol

Whey Protein

Pentylene Glycol

Prunus Amygdalus Dulcis Seed Extract

Porphyridium Cruentum Extract

Acetyl Hexapeptide-8

Palmitoyl Tetrapeptide-7

Palmitoyl Tripeptide-1

Micrococcus Lysate

Pullulan

Taurine

Hydroxypropyl Methylcellulose

Lecithin

Xanthan Gum

Polysorbate 20

CI 42090

CI 17200

Water, Bis-PEG-18 Methyl Ether Dimethyl Silane, Butylene Glycol, Glycerin, Cucumis Sativus Fruit Extract, Hypnea Musciformis Extract, Gelidiella Acerosa Extract, Hordeum Vulgare Extract, Padina Pavonica Thallus Extract, Helianthus Annuus Seedcake, Sucrose, Caffeine, Sodium Hyaluronate, Hydroxyethyl Urea, Hydrolyzed Rice Extract, Sorbitol, Sodium Polyaspartate, PPG-6-Decyltetradeceth-30, Ethylhexylglycerin, Propylene Glycol Dicaprate, Caprylyl Glycol, Trehalose, Polysorbate 80, Carbomer, Sodium Hydroxide, Hexylene Glycol, Citric Acid, Sodium Citrate, Disodium EDTA, Phenoxyethanol, Whey Protein, Pentylene Glycol, Prunus Amygdalus Dulcis Seed Extract, Porphyridium Cruentum Extract, Acetyl Hexapeptide-8, Palmitoyl Tetrapeptide-7, Palmitoyl Tripeptide-1, Micrococcus Lysate, Pullulan, Taurine, Hydroxypropyl Methylcellulose, Lecithin, Xanthan Gum, Polysorbate 20, CI 42090, CI 17200

Dimethicone

Tapioca Starch

Dimethicone Crosspolymer

Retinol

Retinyl Propionate

Niacinamide

Palmitoyl Pentapeptide-4

Polyacrylamide

C13-14 Isoparaffin

DMDM Hydantoin

Laureth-4

Acrylates/C10-30 Alkyl Acrylate Crosspolymer

Laureth-7

Dimethiconol

Polymethylsilsesquioxane

Aminomethyl Propanol

Titanium Dioxide

Iodopropynyl Butylcarbamate

Caprylic/Capric Triglyceride

Water, Dimethicone, Glycerin, Tapioca Starch, Dimethicone Crosspolymer, Retinol, Retinyl Propionate, Niacinamide, Palmitoyl Pentapeptide-4, Polyacrylamide, C13-14 Isoparaffin, DMDM Hydantoin, Polysorbate 20, Laureth-4, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Laureth-7, Dimethiconol, Polymethylsilsesquioxane, Aminomethyl Propanol, Titanium Dioxide, Disodium EDTA, Iodopropynyl Butylcarbamate, Caprylic/Capric Triglyceride

Reviews

Be the first to review

Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Disodium EDTA is a chelating agent. It grabs onto and deactivates metal ions that sneak into your products from water, packaging, or air.

This ingredient mainly works behind the scenes and helps with:

On top of that, this ingredient can counteract the effects of hard water by binding to the minerals in it.

One thing worth knowing is that Disodium EDTA has been shown to be a mild penetration enhancer. It can help other ingredients absorb into skin more effectively which can be a double-edged sword (great for actives, but can also make the active too strong if you have sensitive skin).

Clinical patch testing showed no significant skin irritation at typical use concentrations and minimal dermal absorption.

You'll most likely see this ingredient near the end of an ingredient list. It's typically found in concentrations less than 1%.

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Polysorbate 20 is a gentle, water-soluble emulsifier and mild surfactant. It stops oil and water from separating to keep your formulas blended and stable.

It also acts as a mild penetration enhancer by helping active ingredients absorb slightly better.

The common safety discussion around this ingredient involves a manufacturing byproduct called 1,4-dioxane.

Trace amounts can form during production but the EU's Scientific Committee on Consumer Safety has concluded that levels at/below 10 ppm in finished products are safe (commercial products consistently fall within acceptable margins).

True allergic reactions are uncommon and the CIR Expert Panel has confirmed this ingredient to be safe as used in cosmetics.

Because it is derived from lauric acid, it may not be fungal acne safe.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

Similar Comparisons

The reference edit

Ingredients, questions
& further reading.

Connected source records selected through this article’s public topic index.

01

Formula cabinet

Ingredients & structured notes

Ingredient index

Ingredients Side-by-side

  1. 01Water
  2. 02Dimethicone
  3. 03Glycerin
  4. 04Tapioca Starch
  5. 05Dimethicone Crosspolymer
  6. 06Retinol
  7. 07Retinyl Propionate
  8. 08Niacinamide
  9. 09Palmitoyl Pentapeptide-4
  10. 10Polyacrylamide
  11. 11C13-14 Isoparaffin
  12. 12DMDM Hydantoin
  13. 13Polysorbate 20
  14. 14Laureth-4
  15. 15Acrylates/C10-30 Alkyl Acrylate Crosspolymer
  16. 16Laureth-7
  17. 17Dimethiconol
  18. 18Polymethylsilsesquioxane
  19. 19Aminomethyl Propanol
  20. 20Titanium Dioxide
Source · skinsort.com
02

Product index

Related product references

03

Comparison edit

Read side by side