Skin science article
Clinique Dramatically Different Moisturizing Cream Versus Olehenriksen Strength Trainer Peptide Boost Moisturizer
Clinique Dramatically Different Moisturizing Cream Versus Olehenriksen Strength Trainer Peptide Boost Moisturizer This moisturizer is formulated around Petrolatum and Cucumis Sativus Fruit Extract to hydrate skin. This barrier-repair moisturizer is formulated
Clinique Dramatically Different Moisturizing Cream Versus Olehenriksen Strength Trainer Peptide Boost Moisturizer
This moisturizer is formulated around Petrolatum and Cucumis Sativus Fruit Extract to hydrate skin.
This barrier-repair moisturizer is formulated around Niacinamide and Acetyl Hexapeptide-8 to strengthen the skin barrier and soften the look of wrinkles.
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Glycerin
Dimethicone
Petrolatum
Tridecyl Stearate
Tridecyl Trimellitate
Polyglyceryl-10 Pentastearate
Behenyl Alcohol
Dipentaerythrityl Hexacaprylate/Hexacaprate
Cucumis Sativus Fruit Extract
Hordeum Vulgare Extract
Sodium Stearoyl Lactylate
Caprylyl Glycol
Propylene Glycol Dicaprate
Helianthus Annuus Seedcake
PEG-100 Stearate
Sodium Hyaluronate
Cetyl Alcohol
Butylene Glycol
Tromethamine
Carbomer
Phenoxyethanol
CI 19140
CI 15985
CI 17200
Water, Glycerin, Dimethicone, Petrolatum, Tridecyl Stearate, Tridecyl Trimellitate, Polyglyceryl-10 Pentastearate, Behenyl Alcohol, Dipentaerythrityl Hexacaprylate/Hexacaprate, Cucumis Sativus Fruit Extract, Hordeum Vulgare Extract, Sodium Stearoyl Lactylate, Caprylyl Glycol, Propylene Glycol Dicaprate, Helianthus Annuus Seedcake, PEG-100 Stearate, Sodium Hyaluronate, Cetyl Alcohol, Butylene Glycol, Tromethamine, Carbomer, Phenoxyethanol, CI 19140, CI 15985, CI 17200
Propanediol
Dicaprylyl Carbonate
Methylpropanediol
Cetearyl Alcohol
Stearyl Alcohol
Mangifera Indica Seed Butter
Niacinamide
Acetyl Hexapeptide-1
Acetyl Hexapeptide-8
Acetyl Octapeptide-3
Acetyl Tetrapeptide-2
Acetyl Dipeptide-1 Cetyl Ester
Palmitoyl Tripeptide-1
Palmitoyl Tetrapeptide-7
Carnosine
Ceramide NP
Ceramide AP
Ceramide EOP
Collagen
Serine
Alanine
Glycine
Glutamic Acid
Lysine Hcl
Threonine
Arginine
Proline
Hyaluronic Acid
Linoleic Acid
Linolenic Acid
Sodium PCA
Sodium Lactate
Panthenol
Tocopherol
Tocopheryl Acetate
Betaine
PCA
Cyanocobalamin
Xylitol
Anhydroxylitol
Xylitylglucoside
Sorbitan Olivate
Hydroxyethylcellulose
Xanthan Gum
Cetearyl Olivate
Sorbitan Laurate
Phytosphingosine
Cholesterol
Polysorbate 60
Hydroxyacetophenone
Glycine Soja Oil
Acrylates/C10-30 Alkyl Acrylate Crosspolymer
Polysorbate 20
Ammonium Acryloyldimethyltaurate/Beheneth-25 Methacrylate Crosspolymer
Sodium Phytate
Sodium Lauroyl Lactylate
Pentaerythrityl Tetra-Di-T-Butyl Hydroxyhydrocinnamate
Leuconostoc/Radish Root Ferment Filtrate
Citric Acid
Ethylhexylglycerin
Parfum
Citral
Limonene
Linalool
Water, Propanediol, Dicaprylyl Carbonate, Glycerin, Methylpropanediol, Cetearyl Alcohol, Stearyl Alcohol, Mangifera Indica Seed Butter, Niacinamide, Acetyl Hexapeptide-1, Acetyl Hexapeptide-8, Acetyl Octapeptide-3, Acetyl Tetrapeptide-2, Acetyl Dipeptide-1 Cetyl Ester, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Carnosine, Ceramide NP, Ceramide AP, Ceramide EOP, Collagen, Serine, Alanine, Glycine, Glutamic Acid, Lysine Hcl, Threonine, Arginine, Proline, Hyaluronic Acid, Sodium Hyaluronate, Linoleic Acid, Linolenic Acid, Sodium PCA, Sodium Lactate, Panthenol, Tocopherol, Tocopheryl Acetate, Betaine, PCA, Cyanocobalamin, Xylitol, Anhydroxylitol, Xylitylglucoside, Sorbitan Olivate, Carbomer, Hydroxyethylcellulose, Xanthan Gum, Cetearyl Olivate, Sorbitan Laurate, Phytosphingosine, Cholesterol, Polysorbate 60, Butylene Glycol, Hydroxyacetophenone, Glycine Soja Oil, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Polysorbate 20, Ammonium Acryloyldimethyltaurate/Beheneth-25 Methacrylate Crosspolymer, Dimethicone, Sodium Phytate, Sodium Lauroyl Lactylate, Pentaerythrityl Tetra-Di-T-Butyl Hydroxyhydrocinnamate, Leuconostoc/Radish Root Ferment Filtrate, Citric Acid, Caprylyl Glycol, Ethylhexylglycerin, Phenoxyethanol, Parfum, Citral, Limonene, Linalool
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Alternatives
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:
Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.
Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.
Caprylyl Glycol is a humectant, skin conditioner, emollient, and preservative booster derived from either caprylic acid or synthetically created.
Typical use levels vary from 0.3-1% as a preservative booster and go up to 2% to condition skin.
Because it is not a free-fatty acid, this ingredient is fungal acne safe (there's nothing for Malassezia to feed on).
Carbomer is a synthetic thickening and gelling agent. It's basically the ingredient that gives a lot of serums, gels, creams, and sunscreens their smooth, non-sticky texture.
Although legally permitted at very high levels, carbomers are normally used at concentrations below 1%.
It also needs to be neutralized to actually thicken, and because it is a large molecule, it doesn't really penetrate the skin barrier.
Allergy-wise, the risk is very low. Clinical studies show carbomers have low potential for skin irritation/sensitization even at concentrations up to 100%.
A 2024 UK study patch-tested 1,302 patients and found true allergy to the parent group of carbomer to be rare with no confirmed relevant reactions.
Dimethicone is a type of synthetic silicone created from natural materials such as quartz. It is also known as polydimethylsiloxane.
What it does:
Dimethicone comes in different viscosities:
Depending on the viscosity, dimethicone has different properties.
Ingredients lists don't always show which type is used, so we recommend reaching out to the brand if you have questions about the viscosity.
This ingredient is unlikely to cause irritation because it does not get absorbed into skin. However, people with silicone allergies should be careful about using this ingredient.
Note: Dimethicone may contribute to pilling. This is because it is not oil or water soluble, so pilling may occur when layered with products. When mixed with heavy oils in a formula, the outcome is also quite greasy.
Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Phenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!).
It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome.
On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive.
Another perk of this ingredient is that it stays functional across a wide pH range (3-10).
You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own.
Typical use concentrations range from 0.3-1% depending on the formula, and this ingredient is capped at 1% int the EU.
Safety-wise, the fear mongering does not hold up to the evidence. The EU's Scientific Committee on Consumer Safety and FDA consider it safe as a preservative at up to 1%, including for children of all ages.
Adverse systemic effects only showed up in animal studies at exposures roughly 200x higher than what people get from cosmetics. And despite its very widespread use, this ingredient is a rare sensitizer and allergic reactions are uncommon.
Sodium Hyaluronate is the salt form of hyaluronic acid. It is a long sugar chain that is naturally found in your skin, joints, and connective tissue that maintains hydration and elasticity.
In skincare, it works as a humectant. It pulls water from the environment and deeper layers of skin and binds it to the surface.
Interestingly, the size of the molecule affects its behavior:
Some clinical evidence links low molecular weight versions to improved wrinkle depth, elasticity, anti-inflammatory effects, and barrier repair.
Many serums use a blend of both weights so you can get surface hydration plus longer-lasting and deeper effects.
You'll typically see concentrations between 0.1-2% for this ingredient.
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!