Skin science article
Clinique Dramatically Different Moisturizing Gel Versus Paula's Choice Skin Balancing Invisible Finish Moisture Gel
Clinique Dramatically Different Moisturizing Gel Versus Paula's Choice Skin Balancing Invisible Finish Moisture Gel This moisturizer is formulated around Caffeine and Sodium Hyaluronate to hydrate skin. This pore-care moisturizer is formulated around Niacinami
Clinique Dramatically Different Moisturizing Gel Versus Paula's Choice Skin Balancing Invisible Finish Moisture Gel
This moisturizer is formulated around Caffeine and Sodium Hyaluronate to hydrate skin.
This pore-care moisturizer is formulated around Niacinamide and Avena Sativa Kernel Extract to refine the look of pores and calm redness.
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Dimethicone
Isododecane
Butylene Glycol
Bis-PEG-18 Methyl Ether Dimethyl Silane
Glycerin
Laminaria Saccharina Extract
Polygonum Cuspidatum Root Extract
Saccharomyces Lysate Extract
Cucumis Sativus Fruit Extract
Hordeum Vulgare Extract
Helianthus Annuus Seedcake
Caffeine
Trehalose
Sodium Hyaluronate
Tocopheryl Acetate
Polysilicone-11
Silica
Propylene Glycol Dicaprate
Oleth-10
Lactobacillus Ferment
Laureth-23
Laureth-4
Ammonium Acryloyldimethyltaurate/Vp Copolymer
Carbomer
Caprylyl Glycol
Hexylene Glycol
Tromethamine
Disodium EDTA
Phenoxyethanol
CI 19140
CI 14700
CI 15985
Water, Dimethicone, Isododecane, Butylene Glycol, Bis-PEG-18 Methyl Ether Dimethyl Silane, Glycerin, Laminaria Saccharina Extract, Polygonum Cuspidatum Root Extract, Saccharomyces Lysate Extract, Cucumis Sativus Fruit Extract, Hordeum Vulgare Extract, Helianthus Annuus Seedcake, Caffeine, Trehalose, Sodium Hyaluronate, Tocopheryl Acetate, Polysilicone-11, Silica, Propylene Glycol Dicaprate, Oleth-10, Lactobacillus Ferment, Laureth-23, Laureth-4, Ammonium Acryloyldimethyltaurate/Vp Copolymer, Carbomer, Caprylyl Glycol, Hexylene Glycol, Tromethamine, Disodium EDTA, Phenoxyethanol, CI 19140, CI 14700, CI 15985
Cyclopentasiloxane
Bis-Phenylpropyl Dimethicone
Niacinamide
Avena Sativa Kernel Extract
Camellia Oleifera Leaf Extract
Vitis Vinifera Seed Extract
Triticum Vulgare Germ Oil
Phenyl Trimethicone
Dipotassium Glycyrrhizate
Tetrahexyldecyl Ascorbate
Phospholipids
Superoxide Dismutase
Isohexadecane
Panthenol
Sodium Acrylate/Sodium Acryloyldimethyl Taurate Copolymer
Sodium Carbomer
Dimethicone/Vinyl Dimethicone Crosspolymer
Polysorbate 80
Hydroxyethylcellulose
Ethylhexylglycerin
Water, Cyclopentasiloxane, Butylene Glycol, Glycerin, Bis-Phenylpropyl Dimethicone, Niacinamide, Laminaria Saccharina Extract, Avena Sativa Kernel Extract, Camellia Oleifera Leaf Extract, Vitis Vinifera Seed Extract, Triticum Vulgare Germ Oil, Tocopheryl Acetate, Phenyl Trimethicone, Dimethicone, Dipotassium Glycyrrhizate, Tetrahexyldecyl Ascorbate, Sodium Hyaluronate, Phospholipids, Superoxide Dismutase, Isohexadecane, Panthenol, Sodium Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Sodium Carbomer, Dimethicone/Vinyl Dimethicone Crosspolymer, Polysorbate 80, Hydroxyethylcellulose, Ethylhexylglycerin, Phenoxyethanol
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Alternatives
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:
Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.
Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.
Dimethicone is a type of synthetic silicone created from natural materials such as quartz. It is also known as polydimethylsiloxane.
What it does:
Dimethicone comes in different viscosities:
Depending on the viscosity, dimethicone has different properties.
Ingredients lists don't always show which type is used, so we recommend reaching out to the brand if you have questions about the viscosity.
This ingredient is unlikely to cause irritation because it does not get absorbed into skin. However, people with silicone allergies should be careful about using this ingredient.
Note: Dimethicone may contribute to pilling. This is because it is not oil or water soluble, so pilling may occur when layered with products. When mixed with heavy oils in a formula, the outcome is also quite greasy.
Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
We don't have a description for Laminaria Saccharina Extract yet.
Phenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!).
It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome.
On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive.
Another perk of this ingredient is that it stays functional across a wide pH range (3-10).
You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own.
Typical use concentrations range from 0.3-1% depending on the formula, and this ingredient is capped at 1% int the EU.
Safety-wise, the fear mongering does not hold up to the evidence. The EU's Scientific Committee on Consumer Safety and FDA consider it safe as a preservative at up to 1%, including for children of all ages.
Adverse systemic effects only showed up in animal studies at exposures roughly 200x higher than what people get from cosmetics. And despite its very widespread use, this ingredient is a rare sensitizer and allergic reactions are uncommon.
Sodium Hyaluronate is the salt form of hyaluronic acid. It is a long sugar chain that is naturally found in your skin, joints, and connective tissue that maintains hydration and elasticity.
In skincare, it works as a humectant. It pulls water from the environment and deeper layers of skin and binds it to the surface.
Interestingly, the size of the molecule affects its behavior:
Some clinical evidence links low molecular weight versions to improved wrinkle depth, elasticity, anti-inflammatory effects, and barrier repair.
Many serums use a blend of both weights so you can get surface hydration plus longer-lasting and deeper effects.
You'll typically see concentrations between 0.1-2% for this ingredient.
Tocopheryl Acetate is a stable, shelf-friendly form of vitamin E.
Formulators love it because plain vitamin E oxidizes quickly once it hits air. This acetate version stays stable and resists going off, helping to extend a product's shelf life.
It's actually inactive on its own and works like a slow-release "storage" form; the enzymes in your skin called esterases gradually convert it into active vitamin E over time.
One in vivo study showed 5% of the acetate in the living layer of the epidermis converted to vitamin E after 5 days of application. This study also found the skin gained protection against UV damage even though the conversion was slow and small.
Once converted, vitamin E acts as a skin's main fat-soluble antioxidant that fights free radicals to protect skin from damage.
Topical vitamin E generally boosts the skin's photoprotection, and it reduced UV-damage in animal models.
This ingredient has some brightening potential but it's more of a prevention ingredient than spot-fader. Cell studies show it can slow down melanin production but it's worth noting that it's not the most powerful brightener out there.
Overall, it has a pretty solid safety profile and has been found to be non-irritating and non-comedogenic. Allergic reactions may happen but stay rare due to how widely the ingredient gets used.
The concentration will vary depending on the formula; industry data shows 0.1% in baby lotions, 3% in lipsticks, and 5% in foot powders. You can also find this ingredient at 100% in a pure vitamin E oil.
Most leave-on skincare keeps it at the lower end, often between 0.5-1%.
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!