Coxir Intensive EGF Peptide Cream Versus Coxir Ultra Hyaluronic Cream

Coxir Intensive EGF Peptide Cream Versus Coxir Ultra Hyaluronic Cream

This anti-aging moisturizer is formulated around Niacinamide and Sh-Oligopeptide-1 to soften the look of wrinkles.

This barrier-repair moisturizer is formulated around Sodium Hyaluronate and Butyrospermum Parkii Butter to strengthen the skin barrier and hydrate skin.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Water

Glycerin

Glyceryl Acrylate/Acrylic Acid Copolymer

Propylene Glycol

Butylene Glycol Dicaprylate/Dicaprate

Dimethicone/Vinyl Dimethicone Crosspolymer

Methyl Gluceth-20

Niacinamide

1,2-Hexanediol

Betaine

Diisostearyl Malate

Cyclomethicone

PEG/PPG-18/4 Copolymer

Sodium Acrylate/Sodium Acryloyldimethyl Taurate Copolymer

Isohexadecane

Polysorbate 80

Adenosine

Butylene Glycol

Hydrogenated Lecithin

Sh-Oligopeptide-1

Copper Tripeptide-1

Hydrogenated Vegetable Oil

Tri-C14-15 Alkyl Citrate

Myrciaria Dubia Fruit Extract

Malpighia Emarginata Fruit Extract

Tocopheryl Acetate

Arginine

Carbomer

Panthenol

Lonicera Japonica Flower Extract

Solanum Lycopersicum Fruit Extract

Lilium Tigrinum Extract

Nelumbo Nucifera Seed Extract

Chrysanthemum Indicum Flower Extract

Hydrolyzed Collagen

Acanthopanax Senticosus Root Extract

Punica Granatum Fruit Extract

Panax Ginseng Root Extract

Carthamus Tinctorius Flower Extract

Xanthan Gum

Malva Sylvestris Flower Extract

Buddleja Davidii Extract

Thymus Vulgaris Extract

Camellia Sinensis Callus Culture Extract

Phaseolus Radiatus Meristem Cell Culture Extract

Panax Ginseng Callus Culture Extract

Phenoxyethanol

Ethylhexylglycerin

Parfum

Water, Glycerin, Glyceryl Acrylate/Acrylic Acid Copolymer, Propylene Glycol, Butylene Glycol Dicaprylate/Dicaprate, Dimethicone/Vinyl Dimethicone Crosspolymer, Methyl Gluceth-20, Niacinamide, 1,2-Hexanediol, Betaine, Diisostearyl Malate, Cyclomethicone, PEG/PPG-18/4 Copolymer, Sodium Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Isohexadecane, Polysorbate 80, Adenosine, Butylene Glycol, Hydrogenated Lecithin, Sh-Oligopeptide-1, Copper Tripeptide-1, Hydrogenated Vegetable Oil, Tri-C14-15 Alkyl Citrate, Myrciaria Dubia Fruit Extract, Malpighia Emarginata Fruit Extract, Tocopheryl Acetate, Arginine, Carbomer, Panthenol, Lonicera Japonica Flower Extract, Solanum Lycopersicum Fruit Extract, Lilium Tigrinum Extract, Nelumbo Nucifera Seed Extract, Chrysanthemum Indicum Flower Extract, Hydrolyzed Collagen, Acanthopanax Senticosus Root Extract, Punica Granatum Fruit Extract, Panax Ginseng Root Extract, Carthamus Tinctorius Flower Extract, Xanthan Gum, Malva Sylvestris Flower Extract, Buddleja Davidii Extract, Thymus Vulgaris Extract, Camellia Sinensis Callus Culture Extract, Phaseolus Radiatus Meristem Cell Culture Extract, Panax Ginseng Callus Culture Extract, Phenoxyethanol, Ethylhexylglycerin, Parfum

Sodium Hyaluronate

Caprylic/Capric Triglyceride

Butyrospermum Parkii Butter

Helianthus Annuus Seed Oil

PEG-12 Dimethicone

Hydrolyzed Jojoba Esters

Sodium Polyacrylate

Pvm/Ma Copolymer

Beeswax

Glyceryl Stearate

PEG-100 Stearate

Stearic Acid

Dimethicone

Sorbitan Stearate

Arachidyl Alcohol

Behenyl Alcohol

Arachidyl Glucoside

Triethanolamine

Glycyrrhiza Inflata Root Extract

Psidium Guajava Fruit Extract

Allantoin

Aloe Barbadensis Leaf Extract

Portulaca Oleracea Extract

Cucurbita Pepo Fruit Extract

Snail Secretion Filtrate

Disodium EDTA

Limnanthes Alba Seed Oil

Squalane

Olea Europaea Fruit Oil

Leontopodium Alpinum Extract

Aloe Vera Callus Extract

Chrysanthemum Indicum Callus Culture Extract

Bambusa Vulgaris Callus Culture Extract

Water, Butylene Glycol, Sodium Hyaluronate, Betaine, Caprylic/Capric Triglyceride, 1,2-Hexanediol, Butyrospermum Parkii Butter, Helianthus Annuus Seed Oil, Butylene Glycol Dicaprylate/Dicaprate, PEG-12 Dimethicone, Hydrolyzed Jojoba Esters, Glycerin, Sodium Polyacrylate, Pvm/Ma Copolymer, Cyclomethicone, Beeswax, Glyceryl Stearate, PEG-100 Stearate, Stearic Acid, Dimethicone, Sorbitan Stearate, Arachidyl Alcohol, Behenyl Alcohol, Arachidyl Glucoside, Triethanolamine, Carbomer, Glycyrrhiza Inflata Root Extract, Psidium Guajava Fruit Extract, Malpighia Emarginata Fruit Extract, Allantoin, Aloe Barbadensis Leaf Extract, Portulaca Oleracea Extract, Lilium Tigrinum Extract, Cucurbita Pepo Fruit Extract, Hydrolyzed Collagen, Snail Secretion Filtrate, Disodium EDTA, Limnanthes Alba Seed Oil, Squalane, Olea Europaea Fruit Oil, Leontopodium Alpinum Extract, Malva Sylvestris Flower Extract, Buddleja Davidii Extract, Aloe Vera Callus Extract, Camellia Sinensis Callus Culture Extract, Chrysanthemum Indicum Callus Culture Extract, Bambusa Vulgaris Callus Culture Extract, Ethylhexylglycerin, Parfum

Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

1,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse.

It is a:

Humectant, drawing moisture into the skin

Emollient, helping to soften skin

Solvent, dispersing and stabilizing formulas

Preservative booster, enhancing the antimicrobial activity of other preservatives

Betaine is a humectant. Like hyaluronic acid, it helps attract and retain moisture in the skin. It’s known for being gentle and for helping the skin maintain balanced hydration.

Betaine is mainly used to improve hydration and support calmer skin. It helps skin cells regulate water balance because it functions as an osmolyte.

Some studies suggest betaine may support making skin tone more even.

Fun fact: Betaine naturally exists in the skin and the body. In cosmetic products, it can be either plant-derived (most commonly from sugar beets) or synthetically produced for consistency and stability.

Betaine is also known as trimethylglycine.

Buddleja Davidii Extract is native to China and Japan. It is also known as the Butterfly Bush as it provides food for butterflies.

This ingredient is rich in antioxidants.

Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:

Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.

Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.

This is a lightweight diester (caprylic/capric acid + butylene glycol) with emollient and skin conditioning properties.

According to a manufacturer, this ingredient can help add a "cushiony" oil phase without making it heavy.

Camellia Sinensis Callus Culture Extract comes from the callus of the tea tree plant. A callus is the mass of cells used to cover a plant wound.

Carbomer is a synthetic thickening and gelling agent. It's basically the ingredient that gives a lot of serums, gels, creams, and sunscreens their smooth, non-sticky texture.

Although legally permitted at very high levels, carbomers are normally used at concentrations below 1%.

It also needs to be neutralized to actually thicken, and because it is a large molecule, it doesn't really penetrate the skin barrier.

Allergy-wise, the risk is very low. Clinical studies show carbomers have low potential for skin irritation/sensitization even at concentrations up to 100%.

A 2024 UK study patch-tested 1,302 patients and found true allergy to the parent group of carbomer to be rare with no confirmed relevant reactions.

Cyclomethicone is a class of silicones used to improve the texture of products.

Their cyclic or circular structure decreases stability. This causes quick evaporation when applied to skin. Cyclomethicones are often used as a carrier for other ingredients. Once it evaporates, it leaves a silky barrier on the skin.

The most popular types of cyclomethicones include D5 and D6.

Ethylhexylglycerin is created from glycerin. It is a multitasker ingredient that:

The CIR Expert Panel found minimal skin absorption or sensitization of any kind in a safety assessment. Though this ingredient is considered well-tolerated, a small number of cases of allergic dermatitis have been published since 2002. Just be sure to patch test if you are unsure.

Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations.

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Hydrolyzed Collagen is Collagen (usually sourced from fish, bovine, or porcine byproducts) that's been broken down into smaller peptides. This makes it water-soluble and easy to blend into formulations.

In a formula, it works mainly as a skin-conditioning and moisturizing agent.

The small peptides and amino acids (including Natural Moisturizing Factor components like Hydroxyproline, Serine, and Aspartic Acid) help the surface of the skin hold onto water, feel softer, and look temporarily plumper.

This ingredient also has mild film-forming and antioxidant properties with research showing the antioxidant effect is stronger the lower the molecular weight of the peptides.

It's worth being realistic here:

Topically applied Hydrolyzed Collagen conditions the upper layers of skin rather than rebuilding the structural collagen deep in your dermis (the wrinkle-and-firmness benefits people associate with Collagen mostly come from oral supplements in studies, not topicals).

However, recent lab and skin-model work on Hydrolyzed Fish Collagen has shown promising effects on cell viability and wound healing when used as an active.

Typical concentrations range from 0.2-2%, but the percentage can go much higher in rinse-off or hair products (sometimes even above 50%).

Clinical studies on this ingredient showed no irritation, sensitization, or phototoxicity.

If you are looking for vegan collagen, it usually goes by a different INCI name like hydrolyzed soy protein. Vegan collagen is derived from yeast, bacteria, or plant sources.

The results are varied.

A study from 2021 found hydrolyzed collagen increased elasticity and improved wrinkles in 1,125 participants between age 20 and 70. Another study found increased skin thickness in participants between the ages of 45 to 59.

However, It is difficult to prove that oral collagen will end up working on your skin. Many of the studies using hydrolyzed collagen also add several vitamins and nutrients into the test mixture as well.

Further studies are needed at this time.

Lilium Tigrinum Extract comes from the Lily flower native to east Asia. It is more commonly known as "Tiger Lily".

Tiger Lily contains carotenoids, an antioxidant. Carotenoids give plants a distinct orange/yellow/red colors.

Studies show Tiger Lily has anti-inflammation properties.

This ingredient is also known as acerola or barbados cherry. It is rich in antioxidants and polysaccharides, giving it skin protecting and hydrating properties.

We don't have a description for Malva Sylvestris Flower Extract yet.

Parfum is a catch-all term for an ingredient or more that is used to give a scent to products.

Also called "fragrance", this ingredient can be a blend of hundreds of chemicals or plant oils. This means every product with "fragrance" or "parfum" in the ingredients list is a different mixture.

For instance, Habanolide is a proprietary trade name for a specific aroma chemical. When used as a fragrance ingredient in cosmetics, most aroma chemicals fall under the broad labeling category of “FRAGRANCE” or “PARFUM” according to EU and US regulations.

The term 'parfum' or 'fragrance' is not regulated in many countries. In many cases, it is up to the brand to define this term.

For instance, many brands choose to label themselves as "fragrance-free" because they are not using synthetic fragrances. However, their products may still contain ingredients such as essential oils that are considered a fragrance by INCI standards.

One example is Calendula flower extract. Calendula is an essential oil that still imparts a scent or 'fragrance'.

Depending on the blend, the ingredients in the mixture can cause allergies and sensitivities on the skin. Some ingredients that are known EU allergens include linalool and citronellol.

Parfum can also be used to mask or cover an unpleasant scent.

The bottom line is: not all fragrances/parfum/ingredients are created equally. If you are worried about fragrances, we recommend taking a closer look at an ingredient. And of course, we always recommend speaking with a professional.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

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