Peptide Skincare & BeautySkin science and ingredient guides

Skin science article

Dear, Klairs Midnight Blue Youth Activating Drop Versus The Ordinary "Buffet" + Copper Peptides 1%

Dear, Klairs Midnight Blue Youth Activating Drop Versus The Ordinary "Buffet" + Copper Peptides 1% This anti-aging serum is formulated around Sh-Oligopeptide-1 to soften the look of wrinkles. This anti-aging serum is formulated around Copper Tripeptide-1 and L

Dear, Klairs Midnight Blue Youth Activating Drop Versus The Ordinary "Buffet" + Copper Peptides 1%

This anti-aging serum is formulated around Sh-Oligopeptide-1 to soften the look of wrinkles.

This anti-aging serum is formulated around Copper Tripeptide-1 and Lactococcus Ferment Lysate to soften the look of wrinkles and strengthen the skin barrier.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Water

Butylene Glycol

Sh-Oligopeptide-1

Sh-Polypeptide-1

Vaccinium Angustifolium Fruit Extract

Lecithin

Sorbitan Sesquioleate

1,2-Hexanediol

Caprylyl Glycol

PEG-60 Hydrogenated Castor Oil

Glycerin

Chlorphenesin

Guaiazulene

Ethylhexylglycerin

Adenosine

Water, Butylene Glycol, Sh-Oligopeptide-1, Sh-Polypeptide-1, Vaccinium Angustifolium Fruit Extract, Lecithin, Sorbitan Sesquioleate, 1,2-Hexanediol, Caprylyl Glycol, PEG-60 Hydrogenated Castor Oil, Glycerin, Chlorphenesin, Guaiazulene, Ethylhexylglycerin, Adenosine

Lactococcus Ferment Lysate

Copper Tripeptide-1

Acetyl Hexapeptide-8

Pentapeptide-18

Palmitoyl Tripeptide-1

Palmitoyl Tetrapeptide-7

Palmitoyl Tripeptide-38

Dipeptide Diaminobutyroyl Benzylamide Diacetate

Acetylarginyltryptophyl Diphenylglycine

Sodium Hyaluronate Crosspolymer

Sodium Hyaluronate

Allantoin

Glycine

Alanine

Serine

Valine

Isoleucine

Proline

Threonine

Histidine

Phenylalanine

Arginine

Aspartic Acid

Trehalose

Fructose

Glucose

Maltose

Urea

Sodium PCA

PCA

Sodium Lactate

Citric Acid

Hydroxypropyl Cyclodextrin

Sodium Chloride

Sodium Hydroxide

Pentylene Glycol

Acacia Senegal Gum

Xanthan Gum

Carbomer

Polysorbate 20

Dimethyl Isosorbide

Sodium Benzoate

Phenoxyethanol

Water, Glycerin, Lactococcus Ferment Lysate, Copper Tripeptide-1, Acetyl Hexapeptide-8, Pentapeptide-18, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Palmitoyl Tripeptide-38, Dipeptide Diaminobutyroyl Benzylamide Diacetate, Acetylarginyltryptophyl Diphenylglycine, Sodium Hyaluronate Crosspolymer, Sodium Hyaluronate, Allantoin, Glycine, Alanine, Serine, Valine, Isoleucine, Proline, Threonine, Histidine, Phenylalanine, Arginine, Aspartic Acid, Trehalose, Fructose, Glucose, Maltose, Urea, Sodium PCA, PCA, Sodium Lactate, Citric Acid, Hydroxypropyl Cyclodextrin, Sodium Chloride, Sodium Hydroxide, Butylene Glycol, Pentylene Glycol, Acacia Senegal Gum, Xanthan Gum, Carbomer, Polysorbate 20, Dimethyl Isosorbide, Sodium Benzoate, Caprylyl Glycol, Ethylhexylglycerin, Phenoxyethanol, Chlorphenesin

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Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:

Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.

Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.

Caprylyl Glycol is a humectant, skin conditioner, emollient, and preservative booster derived from either caprylic acid or synthetically created.

Typical use levels vary from 0.3-1% as a preservative booster and go up to 2% to condition skin.

Because it is not a free-fatty acid, this ingredient is fungal acne safe (there's nothing for Malassezia to feed on).

Chlorphenesin is a synthetic preservative. It helps protect a product against bacteria in order to extend shelf life. In most cases, Chlorphenesin is paired with other preservatives such as phenoxyethanol and caprylyl glycol.

Chlorphenesin is a biocide. This means it is able to help fight the microorganisms on our skin. It is also able to fight odor-releasing bacteria.

Chlorphenesin is soluble in both water and glycerin.

Studies show Chlorphenesin is easily absorbed by our skin. You should speak with a skincare professional if you have concerns about using Chlorphenesin.

Ethylhexylglycerin is created from glycerin. It is a multitasker ingredient that:

The CIR Expert Panel found minimal skin absorption or sensitization of any kind in a safety assessment. Though this ingredient is considered well-tolerated, a small number of cases of allergic dermatitis have been published since 2002. Just be sure to patch test if you are unsure.

Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations.

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

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