Derma E Advanced Peptides & Collagen Serum Versus The Ordinary Hyaluronic Acid 2% + B5

Derma E Advanced Peptides & Collagen Serum Versus The Ordinary Hyaluronic Acid 2% + B5

This anti-aging serum is formulated around Palmitoyl Tripeptide-38 and Acetyl Hexapeptide-8 to soften the look of wrinkles and refine skin texture.

This hydrating treatment is formulated around Sodium Hyaluronate and Sodium Hyaluronate Crosspolymer to hydrate skin and strengthen the skin barrier.

What's inside

Key Ingredients

Benefits

Concerns

No concerns

Ingredients Side-by-side

Water

Glycerin

Camellia Sinensis Leaf Extract

Propanediol

Hydroxypropyl Cyclodextrin

Palmitoyl Tripeptide-38

Acetyl Hexapeptide-8

Microcrystalline Cellulose

Cellulose Gum

Panthenol

Pinus Pinaster Bark Extract

Acacia Seyal Gum Extract

Ascorbyl Palmitate

Tocopheryl Acetate

Allantoin

Caprylic/Capric Triglyceride

Ethylhexyl Palmitate

Leucine

Tyrosine

Alanine

Xanthan Gum

Sodium Citrate

Phenoxyethanol

Ethylhexylglycerin

Parfum

Water, Glycerin, Camellia Sinensis Leaf Extract, Propanediol, Hydroxypropyl Cyclodextrin, Palmitoyl Tripeptide-38, Acetyl Hexapeptide-8, Microcrystalline Cellulose, Cellulose Gum, Panthenol, Pinus Pinaster Bark Extract, Acacia Seyal Gum Extract, Ascorbyl Palmitate, Tocopheryl Acetate, Allantoin, Caprylic/Capric Triglyceride, Ethylhexyl Palmitate, Leucine, Tyrosine, Alanine, Xanthan Gum, Sodium Citrate, Phenoxyethanol, Ethylhexylglycerin, Parfum

Sodium Hyaluronate

Pentylene Glycol

Sodium Hyaluronate Crosspolymer

Ahnfeltia Concinna Extract

Trisodium Ethylenediamine Disuccinate

Citric Acid

Isoceteth-20

Ethoxydiglycol

Hexylene Glycol

1,2-Hexanediol

Caprylyl Glycol

Water, Sodium Hyaluronate, Pentylene Glycol, Propanediol, Sodium Hyaluronate Crosspolymer, Panthenol, Ahnfeltia Concinna Extract, Glycerin, Trisodium Ethylenediamine Disuccinate, Citric Acid, Isoceteth-20, Ethoxydiglycol, Ethylhexylglycerin, Hexylene Glycol, 1,2-Hexanediol, Phenoxyethanol, Caprylyl Glycol

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Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Ethylhexylglycerin is created from glycerin. It is a multitasker ingredient that:

The CIR Expert Panel found minimal skin absorption or sensitization of any kind in a safety assessment. Though this ingredient is considered well-tolerated, a small number of cases of allergic dermatitis have been published since 2002. Just be sure to patch test if you are unsure.

Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations.

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Panthenol is a common ingredient that helps hydrate and soothe the skin. It is found naturally in our skin and hair.

There are two forms of panthenol: D and L.

D-panthenol is also known as dexpanthenol. Most cosmetics use dexpanthenol or a mixture of D and L-panthenol.

Panthenol is famous due to its ability to go deeper into the skin's layers. Using this ingredient has numerous pros (and no cons):

Like hyaluronic acid, panthenol is a humectant. Humectants are able to bind and hold large amounts of water to keep skin hydrated.

This ingredient works well for wound healing. It works by increasing tissue in the wound and helps close open wounds.

Once oxidized, panthenol converts to pantothenic acid. Panthothenic acid is found in all living cells.

This ingredient is also referred to as pro-vitamin B5.

Phenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!).

It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome.

On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive.

Another perk of this ingredient is that it stays functional across a wide pH range (3-10).

You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own.

Typical use concentrations range from 0.3-1% depending on the formula, and this ingredient is capped at 1% int the EU.

Safety-wise, the fear mongering does not hold up to the evidence. The EU's Scientific Committee on Consumer Safety and FDA consider it safe as a preservative at up to 1%, including for children of all ages.

Adverse systemic effects only showed up in animal studies at exposures roughly 200x higher than what people get from cosmetics. And despite its very widespread use, this ingredient is a rare sensitizer and allergic reactions are uncommon.

Propanediol is an all-star ingredient. It softens, hydrates, and smooths the skin.

It’s often used to:

Propanediol is not likely to cause sensitivity and considered safe to use. It is derived from corn or petroleum with a clear color and no scent.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

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