Skin science article
Dr.Ceuracle Azelaic 10 & Madeca Ampoule Versus APLB Azelaic Acid Peptide Ampoule Serum
Dr.Ceuracle Azelaic 10 & Madeca Ampoule Versus APLB Azelaic Acid Peptide Ampoule Serum This calming ampoule is formulated around Azelaic Acid and Panthenol to calm redness and clear breakouts. This calming ampoule is formulated around Azelaic Acid and Sh-Oligo
Dr.Ceuracle Azelaic 10 & Madeca Ampoule Versus APLB Azelaic Acid Peptide Ampoule Serum
This calming ampoule is formulated around Azelaic Acid and Panthenol to calm redness and clear breakouts.
This calming ampoule is formulated around Azelaic Acid and Sh-Oligopeptide-1 to calm redness and fade the look of dark spots.
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Azelaic Acid
Propylene Glycol
Sodium Hydroxide
Pentylene Glycol
Hydroxyethylcellulose
Panthenol
Chondrus Crispus Extract
Chlorella Vulgaris Extract
Glucose
Saccharum Officinarum Extract
Glycerin
1,2-Hexanediol
Butylene Glycol
Fructooligosaccharides
Fructose
Ethylhexylglycerin
Dextrin
Theobroma Cacao Extract
Madecassoside
Tocopherol
Arginine
Water, Azelaic Acid, Propylene Glycol, Sodium Hydroxide, Pentylene Glycol, Hydroxyethylcellulose, Panthenol, Chondrus Crispus Extract, Chlorella Vulgaris Extract, Glucose, Saccharum Officinarum Extract, Glycerin, 1,2-Hexanediol, Butylene Glycol, Fructooligosaccharides, Fructose, Ethylhexylglycerin, Dextrin, Theobroma Cacao Extract, Madecassoside, Tocopherol, Arginine
Centella Asiatica Leaf Water
Propanediol
Diethoxyethyl Succinate
Sh-Oligopeptide-1
Madecassic Acid
Asiaticoside
Asiatic Acid
Squalane
Solanum Melongena Fruit Extract
Melaleuca Alternifolia Leaf Extract
Beta-Glucan
Hippophae Rhamnoides Fruit Extract
Nelumbo Nucifera Extract
Artemisia Annua Extract
Oryza Sativa Extract
Saccharomyces Ferment
Dipropylene Glycol
Sodium Citrate
Sodium Hyaluronate
Allantoin
Cellulose Gum
Disodium EDTA
Glyceryl Acrylate/Acrylic Acid Copolymer
Citric Acid
Xanthan Gum
Inulin
Cellulose
Hydroxyacetophenone
Sodium Polyacryloyldimethyl Taurate
Dipotassium Glycyrrhizate
Water, Centella Asiatica Leaf Water, Butylene Glycol, Propanediol, Glycerin, Diethoxyethyl Succinate, Azelaic Acid, Sh-Oligopeptide-1, Madecassic Acid, Asiaticoside, Asiatic Acid, Squalane, Solanum Melongena Fruit Extract, Melaleuca Alternifolia Leaf Extract, Beta-Glucan, Hippophae Rhamnoides Fruit Extract, Nelumbo Nucifera Extract, Artemisia Annua Extract, Oryza Sativa Extract, Saccharomyces Ferment, Dipropylene Glycol, Sodium Citrate, Sodium Hyaluronate, Allantoin, Cellulose Gum, Disodium EDTA, Glyceryl Acrylate/Acrylic Acid Copolymer, Citric Acid, Xanthan Gum, Inulin, Cellulose, Glucose, Fructose, Panthenol, Ethylhexylglycerin, Hydroxyacetophenone, Sodium Polyacryloyldimethyl Taurate, Dipotassium Glycyrrhizate, 1,2-Hexanediol
Reviews
Alternatives
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
1,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse.
It is a:
Humectant, drawing moisture into the skin
Emollient, helping to soften skin
Solvent, dispersing and stabilizing formulas
Preservative booster, enhancing the antimicrobial activity of other preservatives
Azelaic acid is a multitasker ingredient that helps treat acne, pigmentation, and irritation. It is a great option for sensitive skin.
What makes it special?
OTC Azelaic acid is usually available in concentrations from 10-15% and anything over requires a prescription.
Here's what each tier does best:
Unlike other acids, azelaic acid will not make your skin more photosensitive/sun sensitive.
Though this ingredient is naturally occurring in grains like wheat, rye, and barley, it is usually synthetically created for cosmetics to ensure stability and effectiveness.
Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:
Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.
Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.
Ethylhexylglycerin is created from glycerin. It is a multitasker ingredient that:
The CIR Expert Panel found minimal skin absorption or sensitization of any kind in a safety assessment. Though this ingredient is considered well-tolerated, a small number of cases of allergic dermatitis have been published since 2002. Just be sure to patch test if you are unsure.
Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations.
Fructose is fruit/plant sugar. It can be found in apples, figs, and honey.
This ingredient is a humectant. Humectants help draw moisture from the air to your skin, keeping your skin hydrated.
Glucose is a simple sugar (a monosaccharide). In skincare, it is mostly a humectant and skin conditioning agent.
Mechanistically, it has multiple hydroxyl groups that hydrogen-bond to water. This pulls moisture into the upper layers of skin to keep the surface soft and hydrated.
It's worth knowing sugars are already a natural component of the skin's NMF (natural moisturizing factor) so it's a molecule that your stratum corneum is well-acquainted with.
Just so you know, glucose is hydrophilic (water-loving) and the stratum corneum is a strong barrier to hydrophilic compounds. This just means penetration is slow and most of the action is happening on the surface.
Gram-to-gram, glucose is not as efficient as a humectant as glycerin. This is why you'll likely see glycose paired with stronger humectants for a bigger hydration payoff.
In skincare, glucose is typically derived from corn or other starch sources.
Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Panthenol is a common ingredient that helps hydrate and soothe the skin. It is found naturally in our skin and hair.
There are two forms of panthenol: D and L.
D-panthenol is also known as dexpanthenol. Most cosmetics use dexpanthenol or a mixture of D and L-panthenol.
Panthenol is famous due to its ability to go deeper into the skin's layers. Using this ingredient has numerous pros (and no cons):
Like hyaluronic acid, panthenol is a humectant. Humectants are able to bind and hold large amounts of water to keep skin hydrated.
This ingredient works well for wound healing. It works by increasing tissue in the wound and helps close open wounds.
Once oxidized, panthenol converts to pantothenic acid. Panthothenic acid is found in all living cells.
This ingredient is also referred to as pro-vitamin B5.
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!