Dr. Reju-All Advanced PDRN Copper Peptide Serum Versus Dear, Klairs EGF Blue Youth Activating Drop

Dr. Reju-All Advanced PDRN Copper Peptide Serum Versus Dear, Klairs EGF Blue Youth Activating Drop

This anti-aging serum is formulated around Niacinamide and Sodium DNA to soften the look of wrinkles and strengthen the skin barrier.

This anti-aging serum is formulated around Sh-Oligopeptide-1 to soften the look of wrinkles.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Water

Butylene Glycol

Glycerin

Dipropylene Glycol

1,2-Hexanediol

Isopentyldiol

Niacinamide

Caprylic/Capric Triglyceride

Sodium DNA

Copper Tripeptide-1

Acetyl Octapeptide-3

Acetyl Tetrapeptide-5

Acetyl Tetrapeptide-9

Palmitoyl Hexapeptide-12

Palmitoyl Tripeptide-5

Sodium Hyaluronate

Hydrolyzed Collagen

Chamaecyparis Obtusa Oil

Anthemis Nobilis Flower Oil

Guaiazulene

Panthenol

Sorbitol

C12-14 Alketh-12

Sodium Polyacryloyldimethyl Taurate

Acrylates/C10-30 Alkyl Acrylate Crosspolymer

Propanediol

Tromethamine

Ethylhexylglycerin

Allantoin

Sodium PCA

Adenosine

Gellan Gum

Glyceryl Acrylate/Acrylic Acid Copolymer

Agar

Sodium Phytate

Beta-Glucan

Tocopherol

Xanthan Gum

Water, Butylene Glycol, Glycerin, Dipropylene Glycol, 1,2-Hexanediol, Isopentyldiol, Niacinamide, Caprylic/Capric Triglyceride, Sodium DNA, Copper Tripeptide-1, Acetyl Octapeptide-3, Acetyl Tetrapeptide-5, Acetyl Tetrapeptide-9, Palmitoyl Hexapeptide-12, Palmitoyl Tripeptide-5, Sodium Hyaluronate, Hydrolyzed Collagen, Chamaecyparis Obtusa Oil, Anthemis Nobilis Flower Oil, Guaiazulene, Panthenol, Sorbitol, C12-14 Alketh-12, Sodium Polyacryloyldimethyl Taurate, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Propanediol, Tromethamine, Ethylhexylglycerin, Allantoin, Sodium PCA, Adenosine, Gellan Gum, Glyceryl Acrylate/Acrylic Acid Copolymer, Agar, Sodium Phytate, Beta-Glucan, Tocopherol, Xanthan Gum

Sh-Oligopeptide-1

Sh-Polypeptide-1

Vaccinium Angustifolium Fruit Extract

Lecithin

Sorbitan Sesquioleate

Caprylyl Glycol

PEG-60 Hydrogenated Castor Oil

Chlorphenesin

Water, Butylene Glycol, Sh-Oligopeptide-1, Sh-Polypeptide-1, Vaccinium Angustifolium Fruit Extract, Lecithin, Sorbitan Sesquioleate, 1,2-Hexanediol, Caprylyl Glycol, PEG-60 Hydrogenated Castor Oil, Glycerin, Chlorphenesin, Guaiazulene, Ethylhexylglycerin, Adenosine

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Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

1,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse.

It is a:

Humectant, drawing moisture into the skin

Emollient, helping to soften skin

Solvent, dispersing and stabilizing formulas

Preservative booster, enhancing the antimicrobial activity of other preservatives

Adenosine is a purine nucleoside that your body already makes in every cell. In skincare, it acts mainly as a skin conditioning and anti-aging agent.

The way it works is fairly well mapped out:

Your skin has cells called fibroblasts that build collagen (the stuff that keeps skin firm and smooth). Adenosine basically flips a switch on these cells that tells them to get to work making more collagen and other proteins. These cells slow down on their own as skin ages, so Adenosine helps give them a little nudge to keep going.

The clinical backing is pretty solid too.

A blind, randomized, placebo-controlled trial of 126 women aged 45-65 tested a 0.1% cream twice daily and found real improvements in crow's feet and frown lines using a precise 3D skin-mapping technique; these changes showed up by week 3 and held at 2 months.

A later study using Adenosine-loaded dissolving microneedle patches reported gains in wrinkle depth, dermal density, elasticity, and hydration.

On concentrations, South Korea's Ministry of Food and Drug Safety has set 0.04% as the approved functional anti-wrinkle level. You'll typically see this ingredient used somewhere in the 0.04-0.1% range since it works at low doses.

This ingredient has been found safe for cosmetics with the data showing no irritation or sensitization.

Overall, this is a great ingredient for any anti-aging routine and has no photosensitizing effect, so it suits both AM and PM use.

Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:

Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.

Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.

Ethylhexylglycerin is created from glycerin. It is a multitasker ingredient that:

The CIR Expert Panel found minimal skin absorption or sensitization of any kind in a safety assessment. Though this ingredient is considered well-tolerated, a small number of cases of allergic dermatitis have been published since 2002. Just be sure to patch test if you are unsure.

Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations.

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Guaiazulene is a fragrance.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

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