Remedy For Skin Elasticity Copper Peptide Complex Advanced Firming Serum Versus Dr. Reju-All Advanced PDRN Copper Peptide Serum

Remedy For Skin Elasticity Copper Peptide Complex Advanced Firming Serum Versus Dr. Reju-All Advanced PDRN Copper Peptide Serum

This anti-aging serum is formulated around Ectoin and Copper Tripeptide-1 to soften the look of wrinkles and strengthen the skin barrier.

This anti-aging serum is formulated around Niacinamide and Sodium DNA to soften the look of wrinkles and strengthen the skin barrier.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Water

Pentylene Glycol

Isopentyldiol

1,2-Hexanediol

Glycerin

Ectoin

Copper Tripeptide-1

Polyglutamic Acid

Allantoin

Biosaccharide Gum-1

Butylene Glycol

Caprylyl Glycol

Centella Asiatica Extract

Citric Acid

Curcuma Longa Root Extract

Ethylhexylglycerin

Acetyl Hexapeptide-8

Hydroxyacetophenone

Tea-Acrylates/Acrylonitrogens Copolymer

Lactobacillus Ferment

Palmitoyl Tripeptide-5

Phenoxyethanol

Polyacrylate Crosspolymer-5

Polysorbate 60

Sodium Citrate

Sodium Hyaluronate

Sorbitan Isostearate

Superoxide Dismutase

Tocopherol

Trisodium Ethylenediamine Disuccinate

Tromethamine

Water, Pentylene Glycol, Isopentyldiol, 1,2-Hexanediol, Glycerin, Ectoin, Copper Tripeptide-1, Polyglutamic Acid, Allantoin, Biosaccharide Gum-1, Butylene Glycol, Caprylyl Glycol, Centella Asiatica Extract, Citric Acid, Curcuma Longa Root Extract, Ethylhexylglycerin, Acetyl Hexapeptide-8, Hydroxyacetophenone, Tea-Acrylates/Acrylonitrogens Copolymer, Lactobacillus Ferment, Palmitoyl Tripeptide-5, Phenoxyethanol, Polyacrylate Crosspolymer-5, Polysorbate 60, Sodium Citrate, Sodium Hyaluronate, Sorbitan Isostearate, Superoxide Dismutase, Tocopherol, Trisodium Ethylenediamine Disuccinate, Tromethamine

Dipropylene Glycol

Niacinamide

Caprylic/Capric Triglyceride

Sodium DNA

Acetyl Octapeptide-3

Acetyl Tetrapeptide-5

Acetyl Tetrapeptide-9

Palmitoyl Hexapeptide-12

Hydrolyzed Collagen

Chamaecyparis Obtusa Oil

Anthemis Nobilis Flower Oil

Guaiazulene

Panthenol

Sorbitol

C12-14 Alketh-12

Sodium Polyacryloyldimethyl Taurate

Acrylates/C10-30 Alkyl Acrylate Crosspolymer

Propanediol

Sodium PCA

Adenosine

Gellan Gum

Glyceryl Acrylate/Acrylic Acid Copolymer

Agar

Sodium Phytate

Beta-Glucan

Xanthan Gum

Water, Butylene Glycol, Glycerin, Dipropylene Glycol, 1,2-Hexanediol, Isopentyldiol, Niacinamide, Caprylic/Capric Triglyceride, Sodium DNA, Copper Tripeptide-1, Acetyl Octapeptide-3, Acetyl Tetrapeptide-5, Acetyl Tetrapeptide-9, Palmitoyl Hexapeptide-12, Palmitoyl Tripeptide-5, Sodium Hyaluronate, Hydrolyzed Collagen, Chamaecyparis Obtusa Oil, Anthemis Nobilis Flower Oil, Guaiazulene, Panthenol, Sorbitol, C12-14 Alketh-12, Sodium Polyacryloyldimethyl Taurate, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Propanediol, Tromethamine, Ethylhexylglycerin, Allantoin, Sodium PCA, Adenosine, Gellan Gum, Glyceryl Acrylate/Acrylic Acid Copolymer, Agar, Sodium Phytate, Beta-Glucan, Tocopherol, Xanthan Gum

Reviews

Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

1,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse.

It is a:

Humectant, drawing moisture into the skin

Emollient, helping to soften skin

Solvent, dispersing and stabilizing formulas

Preservative booster, enhancing the antimicrobial activity of other preservatives

Allantoin is a soothing ingredient known for its protective and moisturizing properties; it's basically a quiet workhorse ingredient you can find in a huge range of cosmetics.

Though it can be derived from the comfrey plant, allantoin is produced synthetically for cosmetic products to ensure purity.

Research shows it can encourage your skin cells to turn over and renew by stimulating keratinocyte and fibroblast proliferation.

It also has mild keratolytic properties to help loosen and shed dead skin cells without being harsh.

Studies also suggest allantoin can help calm inflammation by dialing down some of the chemical signals your skin sends out when it is irritated.

This ingredient is typically used in the 0.1-0.5% range, and the FDA recognizes it as a skin protectant in OTC products up to 2%.

Overall, allantoin is a wonderful addition to most routines; it is stable across a wide pH range (~4-8), works well with other ingredients, and is considered non-sensitizing/non-irritating.

Fun fact: Allantoin is naturally occurring in comfrey root, beets, chamomile, and wheat sprouts. Our bodies even produce it as a byproduct of uric acid metabolism.

Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:

Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.

Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.

Copper Tripeptide-1 (GHK-Cu) is a skin repairing ingredient known for its ability to boost collagen, improve firmness, and support skin regeneration.

It is a complex made up of a naturally occurring peptide (glycine-histidine-lysine) and copper, an essential trace element.

While studying wound healing, researchers noticed GHK-Cu stimulated hair follicle enlargement and growth by keeping hair in its active growth phase longer. This has made it a promising ingredient for hair regrowth treatments.

Some people have reported increased facial hair. While GHK-Cu can make your hair follicles bigger, it usually doesn’t turn soft, barely-visible facial hairs into thick, dark ones.

Anecdotal reports suggest that overusing copper peptides might lead to premature aging due to excess free copper or enzyme imbalances. This claim isn’t backed by large-scale studies.

Unfortunately, there are limited human studies for this ingredient. While early results are promising, many studies are either small, in-vitro, or not rigorously controlled.

For example, there is a 1998 study that explored the effects of copper tripeptide, vitamin C, tretinoin, and melatonin on skin repair and collagen synthesis.

After one month, increased procollagen production was seen in 7 out of 10 participants using copper tripeptide (more than those using vitamin C, melatonin, or tretinoin.

While the study was exploratory, it offers early evidence that copper tripeptide may support collagen production. Larger, well-designed trials are still needed to confirm its potential and understand individual responses.

Read more about other common types of peptides here:

Ethylhexylglycerin is created from glycerin. It is a multitasker ingredient that:

The CIR Expert Panel found minimal skin absorption or sensitization of any kind in a safety assessment. Though this ingredient is considered well-tolerated, a small number of cases of allergic dermatitis have been published since 2002. Just be sure to patch test if you are unsure.

Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations.

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Isopentyldiol is a synthetic solvent, humectant, and emollient.

Humectants have the ability to attract and hold water while emollients create a thin film to prevent water from evaporating. This combination keeps your skin and hair soft and hydrated. Plus, isopentyldiol does not leave a sticky feeling behind.

As a surfactant, isopentyldiol is a hydrotrope. Hydrotropes help surfactants (cleansing agents) dissolve into water.

According to the manufacturer, using this ingredient with sorbitol boosts skin hydration and helps close cuticles of damaged hair.

This ingredient is water-soluble.

Palmitoyl Tripeptide-5 is a synthetic signal lipopeptide. This just means it is a three amino acid chain bolted onto a palmitic acid tail so it can slip through the skin's lipid barrier.

This peptide has a "build more, lose less" approach.

It's designed to mimic the collagen-stimulating activity in your skin by copying a snippet of one of your skin's own matrix proteins. This nudges fibroblasts into making more collagen while inhibiting the enzyme that breaks down skin protein.

The manufacturer's in vivo study of 45 volunteers found 1% and 2.5% reduced the appearance of wrinkles by 7% and 12% respectively, after using it twice daily for 84 days.

This is in the expected range for peptides; they're slow and cumulative actives and not overnight fixers.

Typical use levels range from 1-3% and this ingredient gets along with pretty much everything.

On the fungal acne front: Although palmitic acid sits in the chain length that Malassezia can feed on, this ingredient has it locked in an amine bond. This makes it hard for Malassezia to access as a source of food, and therefore fungal acne safe.

Sodium Hyaluronate is the salt form of hyaluronic acid. It is a long sugar chain that is naturally found in your skin, joints, and connective tissue that maintains hydration and elasticity.

In skincare, it works as a humectant. It pulls water from the environment and deeper layers of skin and binds it to the surface.

Interestingly, the size of the molecule affects its behavior:

Some clinical evidence links low molecular weight versions to improved wrinkle depth, elasticity, anti-inflammatory effects, and barrier repair.

Many serums use a blend of both weights so you can get surface hydration plus longer-lasting and deeper effects.

You'll typically see concentrations between 0.1-2% for this ingredient.

Tocopherol is a fat-soluble antioxidant known as Vitamin E.

You'll find this ingredient in the vast majority of skincare (for good reason). It works to neutralize free radicals, or unstable molecules generated by UV exposure, pollution, and other environmental stressors, before they can cause oxidative damage to your skin cells.

Topically applied tocopherol has been shown to protect against UV damage by ramping up the skin's own natural defense enzymes.

It also acts as a skin conditioning agent; some studies show that regular topical use can improve the skin's water-binding capacity over 2-4 weeks.

This ingredient is especially loved for being a team player. When combined with Vitamin C, the photoprotective effect of both ingredients roughly doubles and the combo also helps reduce UV-induced DNA damage.

This ingredient has some brightening potential but it's more of a prevention ingredient than spot-fader. Cell studies show it can slow down melanin production but it's worth noting that it's not the most powerful brightener out there.

In formulations, it also serves as a stabilizer that helps protect other oxidation-prone ingredients from degrading.

Concentrations usually range from 0.1-1% in most leave-on products.

Tromethamine (aka THAM) is a synthetic amino acid that shows up in skincare as a helper ingredient.

It functions as a pH adjuster to help neutralize acidic ingredients and set a formula's pH to the right spot.

This matters a lot because a lot of actives (like vitamin C) needs a specific pH to work well and feel comfortable on skin.

Concentration use ranges from 0.1-1.0% depending on the formula.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

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