Skin science article
DRMTLGY Retinol Complex 0.5% Versus Paula's Choice Pro Retinaldehyde Dual-Retinoid Treatment
DRMTLGY Retinol Complex 0.5% Versus Paula's Choice Pro Retinaldehyde Dual-Retinoid Treatment This anti-aging serum is formulated around Sodium Ascorbate and Tocopherol to soften the look of wrinkles and refine skin texture. This anti-aging treatment is formula
DRMTLGY Retinol Complex 0.5% Versus Paula's Choice Pro Retinaldehyde Dual-Retinoid Treatment
This anti-aging serum is formulated around Sodium Ascorbate and Tocopherol to soften the look of wrinkles and refine skin texture.
This anti-aging treatment is formulated around Retinal and Oleyl Adapalenate to soften the look of wrinkles and refine skin texture.
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Cyclopentasiloxane
Dimethicone Crosspolymer
Dimethicone/Vinyl Dimethicone Crosspolymer
Dimethiconol
Caprylic/Capric Triglyceride
Sodium Ascorbate
Tocopherol
Retinol
Cyclopentasiloxane, Dimethicone Crosspolymer, Dimethicone/Vinyl Dimethicone Crosspolymer, Dimethiconol, Caprylic/Capric Triglyceride, Sodium Ascorbate, Tocopherol, Retinol
Water
Simmondsia Chinensis Seed Oil
Dimethicone
Polyglyceryl-2 Stearate
Propanediol
Polyglyceryl-3 Diisostearate
Sodium Stearoyl Glutamate
Retinal
Oleyl Adapalenate
Tocopheryl Acetate
Saccharomyces Ferment Filtrate
Albatrellus Confluens Extract
Punica Granatum Pericarp Extract
Glyceryl Stearate
Stearyl Alcohol
Hydroxyapatite
Butylene Glycol
Cetyl Glyceryl Ether
Ricinus Communis Seed Oil
Sodium Polyacrylate
Isopropyl Myristate
Hydroxyacetophenone
Caprylhydroxamic Acid
Sodium Phytate
Xanthan Gum
Glycerin
Hydroxystearic Acid
Ceramide AP
1,2-Hexanediol
Sorbitan Oleate
Naringin
Citric Acid
Titanium Dioxide
Water, Caprylic/Capric Triglyceride, Simmondsia Chinensis Seed Oil, Dimethicone, Polyglyceryl-2 Stearate, Propanediol, Polyglyceryl-3 Diisostearate, Sodium Stearoyl Glutamate, Retinal, Oleyl Adapalenate, Tocopherol, Tocopheryl Acetate, Saccharomyces Ferment Filtrate, Albatrellus Confluens Extract, Punica Granatum Pericarp Extract, Glyceryl Stearate, Stearyl Alcohol, Hydroxyapatite, Butylene Glycol, Cetyl Glyceryl Ether, Ricinus Communis Seed Oil, Sodium Polyacrylate, Isopropyl Myristate, Hydroxyacetophenone, Caprylhydroxamic Acid, Sodium Phytate, Xanthan Gum, Glycerin, Hydroxystearic Acid, Ceramide AP, 1,2-Hexanediol, Sorbitan Oleate, Naringin, Citric Acid, Titanium Dioxide
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Alternatives
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Caprylic/Capric Triglyceride (aka MCT Oil) is a lightweight emollient, solvent, and texture enhancer. It is considered a skin-softener by helping to prevent moisture loss.
Though it behaves like an oil, it is not technically one due to its chemical composition. One perk of this ingredient is that it is very stable, resistant to oxidation, and unlikely to go rancid.
In practice, that translates to a long shelf life and a consistently elegant skin feel.
While there is an assumption Caprylic Triglyceride can clog pores due to it being derived from coconut oil, there is no research supporting this. Just patch test if you have concerns.
Fractionated coconut oil and MCT Oil are both listed as Caprylic/Capric Triglyceride according to INCI. This is because INCI names are based on the ingredient’s final chemical composition and not its marketing name or source.
This ingredient is treated as the gold standard fungal acne safe oil. Even though it is coconut derived, the problematic lauric acid is stripped out.
This leaves just caprylic (C8) and capric (C10) acid. These chain lengths actually trend antifungal; a 2020 study found caprylic acid was enough to disrupt Malassezia furfur cell membrane, with a caprylic acid derivative damaging membrane structures at concentrations as low as 0.2%.
Tocopherol is a fat-soluble antioxidant known as Vitamin E.
You'll find this ingredient in the vast majority of skincare (for good reason). It works to neutralize free radicals, or unstable molecules generated by UV exposure, pollution, and other environmental stressors, before they can cause oxidative damage to your skin cells.
Topically applied tocopherol has been shown to protect against UV damage by ramping up the skin's own natural defense enzymes.
It also acts as a skin conditioning agent; some studies show that regular topical use can improve the skin's water-binding capacity over 2-4 weeks.
This ingredient is especially loved for being a team player. When combined with Vitamin C, the photoprotective effect of both ingredients roughly doubles and the combo also helps reduce UV-induced DNA damage.
This ingredient has some brightening potential but it's more of a prevention ingredient than spot-fader. Cell studies show it can slow down melanin production but it's worth noting that it's not the most powerful brightener out there.
In formulations, it also serves as a stabilizer that helps protect other oxidation-prone ingredients from degrading.
Concentrations usually range from 0.1-1% in most leave-on products.