Skin science article
DRMTLGY Vitamin C E + F Versus PCA Skin ReBalance
DRMTLGY Vitamin C E + F Versus PCA Skin ReBalance This anti-aging serum is formulated around Ascorbic Acid and Tocopherol to soften the look of wrinkles and brighten dull-looking skin. This calming moisturizer is formulated around Niacinamide and Bisabolol to
DRMTLGY Vitamin C E + F Versus PCA Skin ReBalance
This anti-aging serum is formulated around Ascorbic Acid and Tocopherol to soften the look of wrinkles and brighten dull-looking skin.
This calming moisturizer is formulated around Niacinamide and Bisabolol to calm redness and strengthen the skin barrier.
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Ascorbic Acid
Ethoxydiglycol
PEG-40 Hydrogenated Castor Oil
PPG-26-Buteth-26
Glycerin
Tocopherol
Ferulic Acid
Palmitoyl Tripeptide-1
Palmitoyl Tetrapeptide-7
Ceramide EOP
Ceramide NP
Palmitoyl Tripeptide-5
Ceramide AP
Phytosphingosine
Cholesterol
Sodium Lauroyl Lactylate
Butylene Glycol
Carbomer
Polysorbate 20
Xanthan Gum
Sodium Hyaluronate
Sodium Metabisulfite
Acetyl Octapeptide-3
Phenoxyethanol
Triethanolamine
Panthenol
Water, Ascorbic Acid, Ethoxydiglycol, PEG-40 Hydrogenated Castor Oil, PPG-26-Buteth-26, Glycerin, Tocopherol, Ferulic Acid, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Ceramide EOP, Ceramide NP, Palmitoyl Tripeptide-5, Ceramide AP, Phytosphingosine, Cholesterol, Sodium Lauroyl Lactylate, Butylene Glycol, Carbomer, Polysorbate 20, Xanthan Gum, Sodium Hyaluronate, Sodium Metabisulfite, Acetyl Octapeptide-3, Phenoxyethanol, Triethanolamine, Panthenol
Ethylhexyl Isononanoate
Glycereth-26
Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer
Niacinamide
Polyisobutene
Caprylyl Glycol
Bisabolol
Sodium Hydroxide
Ethylhexylglycerin
Hexylene Glycol
PEG-7 Trimethylolpropane Coconut Ether
Tocopheryl Acetate
Oenothera Biennis Oil
Borago Officinalis Seed Oil
Aloe Barbadensis Leaf Juice
Water, Ethylhexyl Isononanoate, Glycereth-26, Butylene Glycol, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Phenoxyethanol, Niacinamide, Carbomer, Polyisobutene, Caprylyl Glycol, Bisabolol, Sodium Hydroxide, Ethylhexylglycerin, Hexylene Glycol, PEG-7 Trimethylolpropane Coconut Ether, Tocopheryl Acetate, Oenothera Biennis Oil, Borago Officinalis Seed Oil, Aloe Barbadensis Leaf Juice, Sodium Hyaluronate
Reviews
Alternatives
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:
Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.
Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.
Carbomer is a synthetic thickening and gelling agent. It's basically the ingredient that gives a lot of serums, gels, creams, and sunscreens their smooth, non-sticky texture.
Although legally permitted at very high levels, carbomers are normally used at concentrations below 1%.
It also needs to be neutralized to actually thicken, and because it is a large molecule, it doesn't really penetrate the skin barrier.
Allergy-wise, the risk is very low. Clinical studies show carbomers have low potential for skin irritation/sensitization even at concentrations up to 100%.
A 2024 UK study patch-tested 1,302 patients and found true allergy to the parent group of carbomer to be rare with no confirmed relevant reactions.
Phenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!).
It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome.
On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive.
Another perk of this ingredient is that it stays functional across a wide pH range (3-10).
You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own.
Typical use concentrations range from 0.3-1% depending on the formula, and this ingredient is capped at 1% int the EU.
Safety-wise, the fear mongering does not hold up to the evidence. The EU's Scientific Committee on Consumer Safety and FDA consider it safe as a preservative at up to 1%, including for children of all ages.
Adverse systemic effects only showed up in animal studies at exposures roughly 200x higher than what people get from cosmetics. And despite its very widespread use, this ingredient is a rare sensitizer and allergic reactions are uncommon.
Sodium Hyaluronate is the salt form of hyaluronic acid. It is a long sugar chain that is naturally found in your skin, joints, and connective tissue that maintains hydration and elasticity.
In skincare, it works as a humectant. It pulls water from the environment and deeper layers of skin and binds it to the surface.
Interestingly, the size of the molecule affects its behavior:
Some clinical evidence links low molecular weight versions to improved wrinkle depth, elasticity, anti-inflammatory effects, and barrier repair.
Many serums use a blend of both weights so you can get surface hydration plus longer-lasting and deeper effects.
You'll typically see concentrations between 0.1-2% for this ingredient.
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!