Drunk Elephant Protini Powerpeptide Resurfacing Serum Versus Dr. Dennis Gross Skincare Vitamin C Lactic 15% Firm & Bright Serum

Drunk Elephant Protini Powerpeptide Resurfacing Serum Versus Dr. Dennis Gross Skincare Vitamin C Lactic 15% Firm & Bright Serum

This smoothing serum is formulated around Lactic Acid and Sh-Oligopeptide-1 to refine skin texture and soften the look of wrinkles.

This anti-aging serum is formulated around Ascorbic Acid and Lactic Acid to soften the look of wrinkles and brighten dull-looking skin.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Water

Glycerin

Lactic Acid

Dicaprylyl Carbonate

Squalane

Sodium Hydroxide

Glycine Max Seed Extract

Sclerocarya Birrea Seed Oil

Camellia Sinensis Seed Oil

Sodium PCA

Caprylic/Capric Triglyceride

Borago Officinalis Seed Oil

Tremella Fuciformis Polysaccharide

Tocotrienols

Sh-Oligopeptide-1

Sh-Oligopeptide-2

Sh-Polypeptide-1

Sh-Polypeptide-9

Sh-Polypeptide-11

Copper Palmitoyl Heptapeptide-14

Heptapeptide-15 Palmitate

Palmitoyl Tetrapeptide-7

Palmitoyl Tripeptide-1

Palmitoyl Tripeptide-38

Palmitoyl Hexapeptide-12

Tripeptide-1

Pyrus Malus Fruit Extract

Propanediol

Sodium Hyaluronate

Panthenol

Sodium Hyaluronate Crosspolymer

Sodium Lactate

PCA

Alanine

Arginine

Glycine

Histidine

Isoleucine

Phenylalanine

Proline

Serine

Threonine

Valine

Adenosine

Nymphaea Alba Root Extract

Bacillus/Folic Acid Ferment Filtrate Extract

Symphytum Officinale Callus Culture Extract

Dextran

Oryza Sativa Bran Oil

Linoleic Acid

Linolenic Acid

Butylene Glycol

Acetyl Glutamine

Coconut Alkanes

Coco-Caprylate/Caprate

Pentylene Glycol

Isomalt

Lecithin

Xanthan Gum

Aspartic Acid

Phytosphingosine

Phospholipids

Glycine Soja Sterols

Tocopherol

Citric Acid

Lactic Acid/Glycolic Acid Copolymer

Polyvinyl Alcohol

Phenoxyethanol

Sodium Benzoate

Hydroxypropyl Cyclodextrin

Polysorbate 20

Caprylyl Glycol

Phenylpropanol

Chlorphenesin

Carbomer

Glyceryl Caprylate

Ethylhexylglycerin

Water, Glycerin, Lactic Acid, Dicaprylyl Carbonate, Squalane, Sodium Hydroxide, Glycine Max Seed Extract, Sclerocarya Birrea Seed Oil, Camellia Sinensis Seed Oil, Sodium PCA, Caprylic/Capric Triglyceride, Borago Officinalis Seed Oil, Tremella Fuciformis Polysaccharide, Tocotrienols, Sh-Oligopeptide-1, Sh-Oligopeptide-2, Sh-Polypeptide-1, Sh-Polypeptide-9, Sh-Polypeptide-11, Copper Palmitoyl Heptapeptide-14, Heptapeptide-15 Palmitate, Palmitoyl Tetrapeptide-7, Palmitoyl Tripeptide-1, Palmitoyl Tripeptide-38, Palmitoyl Hexapeptide-12, Tripeptide-1, Pyrus Malus Fruit Extract, Propanediol, Sodium Hyaluronate, Panthenol, Sodium Hyaluronate Crosspolymer, Sodium Lactate, PCA, Alanine, Arginine, Glycine, Histidine, Isoleucine, Phenylalanine, Proline, Serine, Threonine, Valine, Adenosine, Nymphaea Alba Root Extract, Bacillus/Folic Acid Ferment Filtrate Extract, Symphytum Officinale Callus Culture Extract, Dextran, Oryza Sativa Bran Oil, Linoleic Acid, Linolenic Acid, Butylene Glycol, Acetyl Glutamine, Coconut Alkanes, Coco-Caprylate/Caprate, Pentylene Glycol, Isomalt, Lecithin, Xanthan Gum, Aspartic Acid, Phytosphingosine, Phospholipids, Glycine Soja Sterols, Tocopherol, Citric Acid, Lactic Acid/Glycolic Acid Copolymer, Polyvinyl Alcohol, Phenoxyethanol, Sodium Benzoate, Hydroxypropyl Cyclodextrin, Polysorbate 20, Caprylyl Glycol, Phenylpropanol, Chlorphenesin, Carbomer, Glyceryl Caprylate, Ethylhexylglycerin

Dipropylene Glycol

Ascorbic Acid

Dimethyl Isosorbide

Ricinoleth-40

Aminomethyl Propanol

Glycyrrhiza Glabra Root Extract

Ferulic Acid

Morus Alba Fruit Extract

Glycolic Acid

Water, Dipropylene Glycol, Ascorbic Acid, Dimethyl Isosorbide, Ricinoleth-40, Aminomethyl Propanol, Lactic Acid, Tocopherol, Glycyrrhiza Glabra Root Extract, Ferulic Acid, Morus Alba Fruit Extract, Sodium Hyaluronate, Glycolic Acid, Adenosine, Glycerin, Phenoxyethanol

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Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Adenosine is a purine nucleoside that your body already makes in every cell. In skincare, it acts mainly as a skin conditioning and anti-aging agent.

The way it works is fairly well mapped out:

Your skin has cells called fibroblasts that build collagen (the stuff that keeps skin firm and smooth). Adenosine basically flips a switch on these cells that tells them to get to work making more collagen and other proteins. These cells slow down on their own as skin ages, so Adenosine helps give them a little nudge to keep going.

The clinical backing is pretty solid too.

A blind, randomized, placebo-controlled trial of 126 women aged 45-65 tested a 0.1% cream twice daily and found real improvements in crow's feet and frown lines using a precise 3D skin-mapping technique; these changes showed up by week 3 and held at 2 months.

A later study using Adenosine-loaded dissolving microneedle patches reported gains in wrinkle depth, dermal density, elasticity, and hydration.

On concentrations, South Korea's Ministry of Food and Drug Safety has set 0.04% as the approved functional anti-wrinkle level. You'll typically see this ingredient used somewhere in the 0.04-0.1% range since it works at low doses.

This ingredient has been found safe for cosmetics with the data showing no irritation or sensitization.

Overall, this is a great ingredient for any anti-aging routine and has no photosensitizing effect, so it suits both AM and PM use.

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Lactic Acid is another well-loved alpha hydroxy acid (AHA). It is gentler than glycolic acid but still highly effective.

Its main role is to exfoliate the surface of the skin by loosening the “glue” that holds dead skin cells together. Shedding those old cells leads to smoother, softer, and more even-toned skin.

Because lactic acid molecules are larger than glycolic acid, they don’t penetrate as deeply. This means they’re less likely to sting or irritate, making it a great choice for beginners or those with sensitive skin.

Like glycolic acid, it can:

Lactic acid also acts as a humectant (like hyaluronic acid). It can draw water into the skin to improve hydration and also plays a role in the skin's natural moisturizing factor (NMF) in the form of sodium lactate.

Studies show it can boost ceramide production to strengthen the skin barrier and even help balance the skin’s microbiome.

To get results, choose products with a pH between 3-4.

Lower strengths (5-12%) focus on surface exfoliation; higher strengths (12% and up) can reach deeper in the dermis (deeper, supportive layer) to improve skin texture and firmness over time.

Though it was originally derived from milk, most modern lactic acid used in skincare is vegan. It is made through non-dairy fermentation to create a bio-identical and stable form suitable for all formulations.

When lactic acid shows up near the end of an ingredient list, it usually means the brand added just a tiny amount to adjust the product’s pH.

Legend has it that Cleopatra used to bathe in sour milk to help reduce wrinkles.

Lactic acid is truly a gentle multitasker: it exfoliates, hydrates, strengthens, and brightens. It's a great ingredient for giving your skin a smooth, glowing, and healthy look without the harshness of stronger acids.

Read more about some other popular AHA's here:

Phenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!).

It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome.

On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive.

Another perk of this ingredient is that it stays functional across a wide pH range (3-10).

You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own.

Typical use concentrations range from 0.3-1% depending on the formula, and this ingredient is capped at 1% int the EU.

Safety-wise, the fear mongering does not hold up to the evidence. The EU's Scientific Committee on Consumer Safety and FDA consider it safe as a preservative at up to 1%, including for children of all ages.

Adverse systemic effects only showed up in animal studies at exposures roughly 200x higher than what people get from cosmetics. And despite its very widespread use, this ingredient is a rare sensitizer and allergic reactions are uncommon.

Sodium Hyaluronate is the salt form of hyaluronic acid. It is a long sugar chain that is naturally found in your skin, joints, and connective tissue that maintains hydration and elasticity.

In skincare, it works as a humectant. It pulls water from the environment and deeper layers of skin and binds it to the surface.

Interestingly, the size of the molecule affects its behavior:

Some clinical evidence links low molecular weight versions to improved wrinkle depth, elasticity, anti-inflammatory effects, and barrier repair.

Many serums use a blend of both weights so you can get surface hydration plus longer-lasting and deeper effects.

You'll typically see concentrations between 0.1-2% for this ingredient.

Tocopherol is a fat-soluble antioxidant known as Vitamin E.

You'll find this ingredient in the vast majority of skincare (for good reason). It works to neutralize free radicals, or unstable molecules generated by UV exposure, pollution, and other environmental stressors, before they can cause oxidative damage to your skin cells.

Topically applied tocopherol has been shown to protect against UV damage by ramping up the skin's own natural defense enzymes.

It also acts as a skin conditioning agent; some studies show that regular topical use can improve the skin's water-binding capacity over 2-4 weeks.

This ingredient is especially loved for being a team player. When combined with Vitamin C, the photoprotective effect of both ingredients roughly doubles and the combo also helps reduce UV-induced DNA damage.

This ingredient has some brightening potential but it's more of a prevention ingredient than spot-fader. Cell studies show it can slow down melanin production but it's worth noting that it's not the most powerful brightener out there.

In formulations, it also serves as a stabilizer that helps protect other oxidation-prone ingredients from degrading.

Concentrations usually range from 0.1-1% in most leave-on products.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

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