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e.l.f. cosmetics Youth Boosting Advanced Night Retinoid Serum Versus Paula's Choice Clinical 0.3% Retinol + 2% Bakuchiol Treatment

e.l.f. cosmetics Youth Boosting Advanced Night Retinoid Serum Versus Paula's Choice Clinical 0.3% Retinol + 2% Bakuchiol Treatment This anti-aging serum is formulated around Hydroxypinacolone Retinoate and Retinal to soften the look of wrinkles and refine skin

e.l.f. cosmetics Youth Boosting Advanced Night Retinoid Serum Versus Paula's Choice Clinical 0.3% Retinol + 2% Bakuchiol Treatment

This anti-aging serum is formulated around Hydroxypinacolone Retinoate and Retinal to soften the look of wrinkles and refine skin texture.

This anti-aging treatment is formulated around Bakuchiol and Tetrahexyldecyl Ascorbate to soften the look of wrinkles and refine skin texture.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Water

Propanediol

PEG-8

Bis-PEG-18 Methyl Ether Dimethyl Silane

Methyl Gluceth-20

Glycereth-26

Butylene Glycol

Diglycerin

Dimethyl Isosorbide

Sodium Acrylates Copolymer

Phenoxyethanol

Lecithin

Tromethamine

Tocopherol

Helianthus Annuus Seed Oil

Bisabolol

Sodium Hyaluronate

Acrylates/C10-30 Alkyl Acrylate Crosspolymer

Ethylhexylglycerin

Caprylyl Glycol

Hydroxypinacolone Retinoate

Dipotassium Glycyrrhizate

Retinal

Disodium EDTA

Glycerin

Vigna Aconitifolia Seed Extract

Sea Water

Maltodextrin

Lactobacillus Ferment Lysate

Hydrolyzed Algin

Euterpe Oleracea Fruit Extract

Sucrose

Carbomer

Coco-Glucoside

Sodium Benzoate

Potassium Sorbate

Palmitoyl Tripeptide-1

Palmitoyl Tetrapeptide-7

Water, Propanediol, PEG-8, Bis-PEG-18 Methyl Ether Dimethyl Silane, Methyl Gluceth-20, Glycereth-26, Butylene Glycol, Diglycerin, Dimethyl Isosorbide, Sodium Acrylates Copolymer, Phenoxyethanol, Lecithin, Tromethamine, Tocopherol, Helianthus Annuus Seed Oil, Bisabolol, Sodium Hyaluronate, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Ethylhexylglycerin, Caprylyl Glycol, Hydroxypinacolone Retinoate, Dipotassium Glycyrrhizate, Retinal, Disodium EDTA, Glycerin, Vigna Aconitifolia Seed Extract, Sea Water, Maltodextrin, Lactobacillus Ferment Lysate, Hydrolyzed Algin, Euterpe Oleracea Fruit Extract, Sucrose, Carbomer, Coco-Glucoside, Sodium Benzoate, Potassium Sorbate, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7

Dimethicone

Pentaerythrityl Tetraisostearate

Isononyl Isononanoate

Bakuchiol

Arachidyl Alcohol

Glyceryl Polymethacrylate

Dimethicone Crosspolymer

Behenyl Alcohol

PEG-75 Shea Butter Glycerides

Glyceryl Stearate

C12-15 Alkyl Benzoate

Polysorbate 20

Tetrahexyldecyl Ascorbate

Retinol

Ceramide Ng

Palmitoyl Hexapeptide-12

Glycyrrhiza Glabra Root Extract

Avena Sativa Kernel Extract

Arctium Lappa Root Extract

Salix Alba Bark Extract

Glycine Soja Sterols

Allantoin

Tocopheryl Acetate

Hydrolyzed Soy Protein

Sodium Hydroxide

Tribehenin

Dipeptide-2

Polygonum Cuspidatum Root Extract

PEG-10 Phytosterol

Magnesium Aluminum Silicate

Arachidyl Glucoside

Chrysin

Pentylene Glycol

Steareth-20

Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer

Cetearyl Alcohol

Hesperidin Methyl Chalcone

N-Hydroxysuccinimide

Benzoic Acid

Water, Dimethicone, Pentaerythrityl Tetraisostearate, Isononyl Isononanoate, Butylene Glycol, Bakuchiol, Arachidyl Alcohol, Glyceryl Polymethacrylate, Dimethicone Crosspolymer, Behenyl Alcohol, Glycerin, PEG-75 Shea Butter Glycerides, Glyceryl Stearate, C12-15 Alkyl Benzoate, Polysorbate 20, Tetrahexyldecyl Ascorbate, Retinol, Ceramide Ng, Palmitoyl Tetrapeptide-7, Palmitoyl Hexapeptide-12, Sodium Hyaluronate, Dipotassium Glycyrrhizate, Glycyrrhiza Glabra Root Extract, Avena Sativa Kernel Extract, Arctium Lappa Root Extract, Salix Alba Bark Extract, Glycine Soja Sterols, Lecithin, Allantoin, Tocopheryl Acetate, Hydrolyzed Soy Protein, Palmitoyl Tripeptide-1, Sodium Hydroxide, Tribehenin, Caprylyl Glycol, Dipeptide-2, Polygonum Cuspidatum Root Extract, PEG-10 Phytosterol, PEG-8, Magnesium Aluminum Silicate, Arachidyl Glucoside, Chrysin, Pentylene Glycol, Sodium Acrylates Copolymer, Steareth-20, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Cetearyl Alcohol, Coco-Glucoside, Hesperidin Methyl Chalcone, N-Hydroxysuccinimide, Disodium EDTA, Phenoxyethanol, Benzoic Acid, Ethylhexylglycerin

Reviews

Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:

Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.

Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.

Caprylyl Glycol is a humectant, skin conditioner, emollient, and preservative booster derived from either caprylic acid or synthetically created.

Typical use levels vary from 0.3-1% as a preservative booster and go up to 2% to condition skin.

Because it is not a free-fatty acid, this ingredient is fungal acne safe (there's nothing for Malassezia to feed on).

Coco-Glucoside is a surfactant, or a cleansing ingredient. It is made from glucose and coconut oil.

Surfactants help gather dirt, oil, and other pollutants from your skin to be rinsed away.

This ingredient is considered gentle and non-comedogenic. However, it may still be irritating for some.

Dipotassium Glycyrrhizate comes from licorice root.

Extracts of licorice have demonstrated to have antibacterial, anti‐inflammatory, antiviral, antioxidant properties.

One component, glabridin, has extra potent antioxidant and soothing properties. It has also been found to block pigmentation from UVB rays in guinea pigs.

Licorice Root also contains a flavonoid. Flavonoids are a natural substance from in plants. Flavonoids also have antioxidant properties.

Another component, glycyrrhizin, has been found to have anti-inflammatory and antimicrobial benefits. This may make licorice root extract effective at treating acne. However, more research is needed to support this.

Liquiritin is one of the flavone compounds found in licorice. It has been found to help lighten skin by preventing tyrosinase from reacting with tyrosine. When the two react, protein is converted to melanin. Melanin is the substance in your body that gives your features pigmentation.

Licorice root is native to Southern Europe and Asia. It has been used in traditional Chinese medicine to help with respiratory issues.

Disodium EDTA is a chelating agent. It grabs onto and deactivates metal ions that sneak into your products from water, packaging, or air.

This ingredient mainly works behind the scenes and helps with:

On top of that, this ingredient can counteract the effects of hard water by binding to the minerals in it.

One thing worth knowing is that Disodium EDTA has been shown to be a mild penetration enhancer. It can help other ingredients absorb into skin more effectively which can be a double-edged sword (great for actives, but can also make the active too strong if you have sensitive skin).

Clinical patch testing showed no significant skin irritation at typical use concentrations and minimal dermal absorption.

You'll most likely see this ingredient near the end of an ingredient list. It's typically found in concentrations less than 1%.

Ethylhexylglycerin is created from glycerin. It is a multitasker ingredient that:

The CIR Expert Panel found minimal skin absorption or sensitization of any kind in a safety assessment. Though this ingredient is considered well-tolerated, a small number of cases of allergic dermatitis have been published since 2002. Just be sure to patch test if you are unsure.

Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations.

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Lecithin is a term for a group of substances found in the cell membranes of plants, animals, and humans. They are made up of phospholipids.

Thanks to its amphiphilic structure (water-loving head and oil-loving tail), it is a true multitasker:

It plays well with most ingredients and is typically used at 0.1-1%. However, concentrations up to 50% have been reported in moisturizers.

Palmitoyl Tetrapeptide-7 (formerly Palmitoyl Tetrapeptide-3) is a synthetic peptide. Its main job is to fight what researchers call "inflammaging".

"Inflammaging" is the slow, low-grade chronic inflammation that quietly breaks down collagen as we age.

This ingredient calms down a specific inflammation signal in your skin cells (called IL-6). When left unchecked, this signal triggers enzymes that break down collagen and elastin.

Clinical testing showed statistically significant improvements in:

Studies also found the more of this ingredient used, the more your skin produces Collagen I, fibronectin, and hyaluronic acid.

You'll likely see this ingredient paired with Palmitoyl Tripeptide-1 in the well-known Matrixyl 3000 complex for enhanced anti-aging effects.

A 3% concentration applied twice daily for two months showed meaningful skin rejuvenation results in clinical panels.

Fungal acne note: Usually a palmitic acid component can feed Malassezia in unbound form, but here is is covalently bonded to the peptide. This means it is very difficult for Malassezia to access, and therefore very unlikely to cause fungal acne.

Palmitoyl Tripeptide-1 (aka Pal-GHK) is a synthetic signal peptide made of three amino acids attached to palmitic acid.

That fatty acid attachment is the key: it boosts the peptide's ability to penetrate the skin barrier. This puts it closer to the dermal cells where it can actually make a difference.

Once there, it acts as a matrikine, a signaling peptide that prompts fibroblasts to produce more collagen, fibronectin, and hyaluronic acid.

In vitro studies show it can boost collagen production in skin cells even when UV-damaged skin samples were treated with it at a tiny concentration (it almost fully restored dermal collagen at 5ppm). It achieved this at 100x lower concentration than retinoic acid, which needed 500 ppm to do the same thing.

Human clinical data is promising, but modest:

A study of 23 female volunteers found a small but statistically significant increase (~4%) in skin thickness after treatment at 4 ppm.

A separate small trial of 15 women showed statistically significant reductions in wrinkle length, depth, and skin roughness after applying it twice daily for four weeks.

You'll likely see Pal-GHK paired with Palmitoyl Tetrapeptide-7 as part of the Matrixyl 3000 complex.

PEG-8 is a synthetic polymer used as a humectant and solvent.

This ingredient is able to help dissolve active ingredients, including water. This gives it humectant properties.

It is soluble in water. The number '8' stands for the molecular weight of the ingredient.

Phenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!).

It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome.

On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive.

Another perk of this ingredient is that it stays functional across a wide pH range (3-10).

You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own.

Typical use concentrations range from 0.3-1% depending on the formula, and this ingredient is capped at 1% int the EU.

Safety-wise, the fear mongering does not hold up to the evidence. The EU's Scientific Committee on Consumer Safety and FDA consider it safe as a preservative at up to 1%, including for children of all ages.

Adverse systemic effects only showed up in animal studies at exposures roughly 200x higher than what people get from cosmetics. And despite its very widespread use, this ingredient is a rare sensitizer and allergic reactions are uncommon.

This ingredient is a synthetic, salt form polymer built from acrylic acid, ethacrylic acid, or their simple esters. It works as a binder, film former, and viscosity increasing agent.

Typical concentrations start at around 0.5% but can go up to 25% for film-forming or binding.

The CIR Expert Panel assessed the safety of 126 acrylates copolymers and concluded they are safe in cosmetics at current use levels when formulated to be non-irritating. They also noted the levels present in finished cosmetic products are not considered a safety risk and Genotoxicity testing (Ames tests, chromosomal aberration assays) has come back negative across the board.

Though the raw building blocks (like acrylic acid) can be irritating on their own, cosmetic-grade versions go through purification to keep levels extremely low.

Sodium Acrylates Copolymer is a large molecule that doesn't penetrate skin barrier in any meaningful way.

Sodium Hyaluronate is the salt form of hyaluronic acid. It is a long sugar chain that is naturally found in your skin, joints, and connective tissue that maintains hydration and elasticity.

In skincare, it works as a humectant. It pulls water from the environment and deeper layers of skin and binds it to the surface.

Interestingly, the size of the molecule affects its behavior:

Some clinical evidence links low molecular weight versions to improved wrinkle depth, elasticity, anti-inflammatory effects, and barrier repair.

Many serums use a blend of both weights so you can get surface hydration plus longer-lasting and deeper effects.

You'll typically see concentrations between 0.1-2% for this ingredient.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

Similar Comparisons

The reference edit

Ingredients, questions
& further reading.

Connected source records selected through this article’s public topic index.

01

Formula cabinet

Ingredients & structured notes

Ingredient index

Ingredients Explained

  1. 01These ingredients are found in both products.
  2. 02Ingredients higher up in an ingredient list are typically present in a larger amount.
  3. 03Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
  4. 04Topically, glycerin does several things at once:
  5. 05Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
  6. 06Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
  7. 07This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
  8. 08Just know very high concentrations (>40%) can feel tacky in low humidity.
  9. 09Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
  10. 10Phenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!).
  11. 11It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome.
  12. 12On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive.
  13. 13Another perk of this ingredient is that it stays functional across a wide pH range (3-10).
  14. 14You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own.
  15. 15Typical use concentrations range from 0.3-1% depending on the formula, and this ingredient is capped at 1% int the EU.
  16. 16Safety-wise, the fear mongering does not hold up to the evidence. The EU's Scientific Committee on Consumer Safety and FDA consider it safe as a preservative at up to 1%, including for children of all ages.
  17. 17Adverse systemic effects only showed up in animal studies at exposures roughly 200x higher than what people get from cosmetics. And despite its very widespread use, this ingredient is a rare sensitizer and allergic reactions are uncommon.
  18. 18Superoxide Dismutase is found in all living cells. This ingredient is AKA as 'SOD'.
  19. 19SOD is a strong antioxidant. It protects living cells against oxidative damage by breaking down radical molecules into regular oxygen and hydrogen peroxide.
  20. 20Antioxidants help fight free-radical molecules that may damage your skin's DNA. This may help with the signs of aging. Due to its antioxidant property, it is used to help treat chronic inflammation.
Source · skinsort.com
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03

Comparison edit

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