Ebanel Labs Hyaluronic Peptide Serum Versus Allies of Skin Mandelic Pigmentation Corrector Night Serum

Ebanel Labs Hyaluronic Peptide Serum Versus Allies of Skin Mandelic Pigmentation Corrector Night Serum

This hydrating serum is formulated around Niacinamide and Sodium Hyaluronate to hydrate skin and soften the look of wrinkles.

This brightening serum is formulated around Mandelic Acid and Niacinamide to fade the look of dark spots and refine skin texture.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Water

Niacinamide

Glycerin

Sodium Hyaluronate

Aloe Barbadensis Leaf Juice

Butylene Glycol

Arbutin

Acetyl Hexapeptide-8

Nonapeptide-1

Palmitoyl Tripeptide-1

Palmitoyl Tripeptide-7 Hcl

Palmitoyl Tripeptide-37

Sh-Decapeptide-9

Sh-Oligopeptide-1

Rh-Polypeptide-45

Sh-Polypeptide-16

Sh-Polypeptide-22

Thuja Orientalis Leaf Extract

Zanthoxylum Schinifolium Leaf Extract

Polygonum Cuspidatum Root Extract

Malus Domestica Fruit Cell Culture Extract

Vitis Vinifera Callus Culture Extract

1,2-Hexanediol

Phospholipids

Ascorbyl Palmitate

Retinyl Palmitate

Tocopheryl Acetate

Panthenol

Dimethyl Sulfone

Simmondsia Chinensis Seed Oil

Persea Gratissima Oil

Argania Spinosa Kernel Oil

Ethylhexylglycerin

Propylene Glycol

Magnesium Ascorbyl Phosphate

Ascorbic Acid

Polysorbate 20

Dextran

Carbomer

Sodium Benzoate

Phenoxyethanol

Water, Niacinamide, Glycerin, Sodium Hyaluronate, Aloe Barbadensis Leaf Juice, Butylene Glycol, Arbutin, Acetyl Hexapeptide-8, Nonapeptide-1, Palmitoyl Tripeptide-1, Palmitoyl Tripeptide-7 Hcl, Palmitoyl Tripeptide-37, Sh-Decapeptide-9, Sh-Oligopeptide-1, Rh-Polypeptide-45, Sh-Polypeptide-16, Sh-Polypeptide-22, Thuja Orientalis Leaf Extract, Zanthoxylum Schinifolium Leaf Extract, Polygonum Cuspidatum Root Extract, Malus Domestica Fruit Cell Culture Extract, Vitis Vinifera Callus Culture Extract, 1,2-Hexanediol, Phospholipids, Ascorbyl Palmitate, Retinyl Palmitate, Tocopheryl Acetate, Panthenol, Dimethyl Sulfone, Simmondsia Chinensis Seed Oil, Persea Gratissima Oil, Argania Spinosa Kernel Oil, Ethylhexylglycerin, Propylene Glycol, Magnesium Ascorbyl Phosphate, Ascorbic Acid, Polysorbate 20, Dextran, Carbomer, Sodium Benzoate, Phenoxyethanol

Mandelic Acid

Lactic Acid

Rosa Canina Fruit Oil

Calophyllum Inophyllum Seed Oil

Salicylic Acid

Superoxide Dismutase

Bakuchiol

Rumex Occidentalis Extract

Ascophyllum Nodosum Extract

Palmitoyl Tripeptide-5

Acetyl Tetrapeptide-40

Pterocarpus Marsupium Bark Extract

Glutamic Acid

Phenyl T-Butylnitrone

Resveratrol Dimethyl Ether

Camellia Sinensis Leaf Extract

Tocopherol

Caprylic/Capric Triglyceride

Xanthan Gum

Sclerotium Gum

Caprylyl Glycol

Sorbitol

Sodium Gluconate

Disodium Succinate

Acetyl Tributyl Citrate

O-Cymen-5-Ol

Sodium Hydroxide

Water, Mandelic Acid, Glycerin, Butylene Glycol, Niacinamide, Polysorbate 20, Lactic Acid, Rosa Canina Fruit Oil, Calophyllum Inophyllum Seed Oil, Salicylic Acid, Superoxide Dismutase, Bakuchiol, Sodium Hyaluronate, Rumex Occidentalis Extract, Ascophyllum Nodosum Extract, Nonapeptide-1, Palmitoyl Tripeptide-5, Acetyl Tetrapeptide-40, Pterocarpus Marsupium Bark Extract, Glutamic Acid, Phenyl T-Butylnitrone, Resveratrol Dimethyl Ether, Camellia Sinensis Leaf Extract, Panthenol, Tocopheryl Acetate, Ascorbic Acid, Tocopherol, Caprylic/Capric Triglyceride, Xanthan Gum, Sclerotium Gum, Ethylhexylglycerin, Caprylyl Glycol, Sorbitol, Dextran, Sodium Gluconate, Disodium Succinate, Acetyl Tributyl Citrate, O-Cymen-5-Ol, Sodium Hydroxide, Phenoxyethanol

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Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Ascorbic Acid is is pure Vitamin C and is the biologically active form used directly by skin.

Not only is vitamin C great for your overall health and immune system, but it also has plenty of benefits for your skin. It is best supported by academic literature for:

Topical vitamin C has been shown to help neutralize oxidative stress from UV and pollution, helping to improve photoaging and hyperpigmentation when used consistently.

One clinical study found that using 5% topical vitamin C for six months improved signs of photodamaged skin, both on the surface and in the deeper structural layers of the skin.

While vitamin C doesn’t replace sunscreen, studies show it can boost photoprotection when combined with Vitamin E and ferulic acid. These two ingredients help improve stability and protective effects.

The big downside of this ingredient is formulation difficulty. Vitamin C is prone to oxidation and doesn't penetrate the skin unless formulated correctly. Research found that vitamin C absorbs into the skin best at a low pH (< 3.5) with about 20% being the upper limit for effective absorption.

Skin levels can saturate after repeated application; this means your skin won’t keep absorbing more once it’s full of vitamin C. This is why more isn’t always better with vitamin C and why very high concentrations don’t necessarily give extra benefits.

Ascorbic acid generally works well with many skincare ingredients but can be irritating when combined with other active ingredients. Strong oxidizing acne treatments like benzoyl peroxide can reduce the effectiveness of vitamin C if they are used at the same time; they are often recommended for use at different times of day.

Read more about other types of Vitamin C:

Foods rich with vitamin C include oranges, strawberries, broccoli, bell peppers, and more. When consuming Vitamin C, your skin receives a portion of the nutrients.

Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:

Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.

Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.

Dextran is a sugar (polysaccharide) with skin hydrating properties.

Fun fact: Louis Pasteur first discovered this ingredient as a microbial product in wine.

Ethylhexylglycerin is created from glycerin. It is a multitasker ingredient that:

The CIR Expert Panel found minimal skin absorption or sensitization of any kind in a safety assessment. Though this ingredient is considered well-tolerated, a small number of cases of allergic dermatitis have been published since 2002. Just be sure to patch test if you are unsure.

Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations.

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Niacinamide is a multitasking form of vitamin B3 that strengthens the skin barrier, reduces pores and dark spots, regulates oil, and improves signs of aging.

And the best part? It's gentle and well-tolerated by most skin types, including sensitive and reactive skin.

You might have heard of "niacin flush", or the reddening of skin that causes itchiness. Niacinamide has not been found to cause this.

In very rare cases, some individuals may not be able to tolerate niacinamide at all or experience an allergic reaction to it.

If you are experiencing flaking, irritation, and dryness with this ingredient, be sure to double check all your products as this ingredient can be found in all categories of skincare.

When incorporating niacinamide into your routine, look out for concentration amounts. Typically, 5% niacinamide provides benefits such as fading dark spots. However, if you have sensitive skin, it is better to begin with a smaller concentration.

When you apply niacinamide to your skin, your body converts it into nicotinamide adenine dinucleotide (NAD). NAD is an essential coenzyme that is already found in your cells as "fuel" and powers countless biological processes.

In your skin, NAD helps repair cell damage, produce new healthy cells, support collagen production, strengthen the skin barrier, and fight environmental stressors (like UV and pollution).

Our natural NAD levels start to decline with age, leading to slower skin repair, visible aging, and a weaker skin barrier. By providing your skin niacinamide, you're recharging your skin's NAD levels. This leads to stronger, healthier, and younger looking skin.

Another name for vitamin B3 is nicotinamide. This vitamin is water-soluble and our bodies don't store it. We obtain Vitamin B3 from either food or skincare. Meat, fish, wheat, yeast, and leafy greens contain vitamin B3.

The type of niacinamide used in skincare is synthetically created.

Nonapeptide-1 is created from amino acids including arginine and lysine.

It has antioxidant and antimicrobial properties.

Emerging studies show Nonapeptide-1 to help with reducing pigmentation and brightening the skin. It has shown to prevent the activation of tyrosinase, an enzyme in the skin that begins the process of melanin creation. Melanin is responsible for giving skin a tan or dark spots.

Panthenol is a common ingredient that helps hydrate and soothe the skin. It is found naturally in our skin and hair.

There are two forms of panthenol: D and L.

D-panthenol is also known as dexpanthenol. Most cosmetics use dexpanthenol or a mixture of D and L-panthenol.

Panthenol is famous due to its ability to go deeper into the skin's layers. Using this ingredient has numerous pros (and no cons):

Like hyaluronic acid, panthenol is a humectant. Humectants are able to bind and hold large amounts of water to keep skin hydrated.

This ingredient works well for wound healing. It works by increasing tissue in the wound and helps close open wounds.

Once oxidized, panthenol converts to pantothenic acid. Panthothenic acid is found in all living cells.

This ingredient is also referred to as pro-vitamin B5.

Phenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!).

It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome.

On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive.

Another perk of this ingredient is that it stays functional across a wide pH range (3-10).

You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own.

Typical use concentrations range from 0.3-1% depending on the formula, and this ingredient is capped at 1% int the EU.

Safety-wise, the fear mongering does not hold up to the evidence. The EU's Scientific Committee on Consumer Safety and FDA consider it safe as a preservative at up to 1%, including for children of all ages.

Adverse systemic effects only showed up in animal studies at exposures roughly 200x higher than what people get from cosmetics. And despite its very widespread use, this ingredient is a rare sensitizer and allergic reactions are uncommon.

Polysorbate 20 is a gentle, water-soluble emulsifier and mild surfactant. It stops oil and water from separating to keep your formulas blended and stable.

It also acts as a mild penetration enhancer by helping active ingredients absorb slightly better.

The common safety discussion around this ingredient involves a manufacturing byproduct called 1,4-dioxane.

Trace amounts can form during production but the EU's Scientific Committee on Consumer Safety has concluded that levels at/below 10 ppm in finished products are safe (commercial products consistently fall within acceptable margins).

True allergic reactions are uncommon and the CIR Expert Panel has confirmed this ingredient to be safe as used in cosmetics.

Because it is derived from lauric acid, it may not be fungal acne safe.

Sodium Hyaluronate is the salt form of hyaluronic acid. It is a long sugar chain that is naturally found in your skin, joints, and connective tissue that maintains hydration and elasticity.

In skincare, it works as a humectant. It pulls water from the environment and deeper layers of skin and binds it to the surface.

Interestingly, the size of the molecule affects its behavior:

Some clinical evidence links low molecular weight versions to improved wrinkle depth, elasticity, anti-inflammatory effects, and barrier repair.

Many serums use a blend of both weights so you can get surface hydration plus longer-lasting and deeper effects.

You'll typically see concentrations between 0.1-2% for this ingredient.

Tocopheryl Acetate is a stable, shelf-friendly form of vitamin E.

Formulators love it because plain vitamin E oxidizes quickly once it hits air. This acetate version stays stable and resists going off, helping to extend a product's shelf life.

It's actually inactive on its own and works like a slow-release "storage" form; the enzymes in your skin called esterases gradually convert it into active vitamin E over time.

One in vivo study showed 5% of the acetate in the living layer of the epidermis converted to vitamin E after 5 days of application. This study also found the skin gained protection against UV damage even though the conversion was slow and small.

Once converted, vitamin E acts as a skin's main fat-soluble antioxidant that fights free radicals to protect skin from damage.

Topical vitamin E generally boosts the skin's photoprotection, and it reduced UV-damage in animal models.

This ingredient has some brightening potential but it's more of a prevention ingredient than spot-fader. Cell studies show it can slow down melanin production but it's worth noting that it's not the most powerful brightener out there.

Overall, it has a pretty solid safety profile and has been found to be non-irritating and non-comedogenic. Allergic reactions may happen but stay rare due to how widely the ingredient gets used.

The concentration will vary depending on the formula; industry data shows 0.1% in baby lotions, 3% in lipsticks, and 5% in foot powders. You can also find this ingredient at 100% in a pure vitamin E oil.

Most leave-on skincare keeps it at the lower end, often between 0.5-1%.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

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