Skin science article
EltaMD, Inc PM Therapy Facial Moisturizer Versus Paula's Choice Skin Recovery Replenishing Moisturizer
EltaMD, Inc PM Therapy Facial Moisturizer Versus Paula's Choice Skin Recovery Replenishing Moisturizer This barrier-repair night moisturizer is formulated around Niacinamide and Hydroxypropyl Bispalmitamide Mea to strengthen the skin barrier and hydrate skin.
EltaMD, Inc PM Therapy Facial Moisturizer Versus Paula's Choice Skin Recovery Replenishing Moisturizer
This barrier-repair night moisturizer is formulated around Niacinamide and Hydroxypropyl Bispalmitamide Mea to strengthen the skin barrier and hydrate skin.
This barrier-repair moisturizer is formulated around Oenothera Biennis Oil and Panthenol to strengthen the skin barrier and hydrate skin.
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Ethylhexyl Isononanoate
Niacinamide
Glyceryl Stearate
PEG-100 Stearate
Glycerin
Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer
Butylene Glycol
Glycereth-26
C10-30 Cholesterol/Lanosterol Esters
Isomerized Safflower Acid
Phenoxyethanol
Hydroxypropyl Bispalmitamide Mea
Xanthan Gum
Cetearyl Glucoside
Tocopheryl Acetate
Hydrolyzed Caesalpinia Spinosa Gum
Oleth-3 Phosphate
Oleic Acid
Polysorbate 60
Sorbitan Isostearate
Caesalpinia Spinosa Gum
Hydrolyzed Rice Protein
Disodium EDTA
Thioctic Acid
Sodium Hyaluronate
Sodium Hydroxide
Sodium Bisulfite
Iodopropynyl Butylcarbamate
Water, Ethylhexyl Isononanoate, Niacinamide, Glyceryl Stearate, PEG-100 Stearate, Glycerin, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Butylene Glycol, Glycereth-26, C10-30 Cholesterol/Lanosterol Esters, Isomerized Safflower Acid, Phenoxyethanol, Hydroxypropyl Bispalmitamide Mea, Xanthan Gum, Cetearyl Glucoside, Tocopheryl Acetate, Hydrolyzed Caesalpinia Spinosa Gum, Oleth-3 Phosphate, Oleic Acid, Polysorbate 60, Sorbitan Isostearate, Caesalpinia Spinosa Gum, Hydrolyzed Rice Protein, Disodium EDTA, Thioctic Acid, Sodium Hyaluronate, Sodium Hydroxide, Sodium Bisulfite, Iodopropynyl Butylcarbamate
Cetearyl Ethylhexanoate
Oenothera Biennis Oil
Cetyl Alcohol
Neopentyl Glycol Diheptanoate
Cyclopentasiloxane
Stearic Acid
Cyclohexasiloxane
Dimethicone
Panthenol
Palmitoyl Tripeptide-1
Palmitoyl Tetrapeptide-7
Tocopheryl Linoleate
Tocopherol
Magnesium Ascorbyl Phosphate
Ascorbyl Palmitate
Dipotassium Glycyrrhizate
Sodium PCA
Anthemis Nobilis Flower Extract
Aloe Barbadensis Leaf Juice
Sodium Ascorbyl Phosphate
Linoleic Acid
Linolenic Acid
Pentaerythrityl Tetra-Di-T-Butyl Hydroxyhydrocinnamate
Saccharide Isomerate
Hydroxypropyl Guar
Allantoin
Rosa Moschata Seed Oil
Polysorbate 20
Cetyl Hydroxyethylcellulose
Carbomer
Sodium Citrate
Trisodium EDTA
Batyl Alcohol
Chlorphenesin
Benzoic Acid
Sorbic Acid
Water, Cetearyl Ethylhexanoate, Butylene Glycol, Glycereth-26, Oenothera Biennis Oil, Cetyl Alcohol, Neopentyl Glycol Diheptanoate, Cyclopentasiloxane, Stearic Acid, Glyceryl Stearate, PEG-100 Stearate, Glycerin, Cyclohexasiloxane, Dimethicone, Panthenol, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Sodium Hyaluronate, Tocopheryl Linoleate, Tocopheryl Acetate, Tocopherol, Magnesium Ascorbyl Phosphate, Ascorbyl Palmitate, Dipotassium Glycyrrhizate, Sodium PCA, Anthemis Nobilis Flower Extract, Aloe Barbadensis Leaf Juice, Sodium Ascorbyl Phosphate, Linoleic Acid, Linolenic Acid, Pentaerythrityl Tetra-Di-T-Butyl Hydroxyhydrocinnamate, Saccharide Isomerate, Hydroxypropyl Guar, Allantoin, Rosa Moschata Seed Oil, Polysorbate 20, Cetyl Hydroxyethylcellulose, Carbomer, Sodium Citrate, Trisodium EDTA, Batyl Alcohol, Sodium Hydroxide, Phenoxyethanol, Chlorphenesin, Benzoic Acid, Sorbic Acid
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Alternatives
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:
Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.
Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.
Glycereth-26 is a synthetic ingredient and polyethylene glycol ether of Glycerin. Glycerin is already naturally found in your skin and helps keep your skin moisturized.
It is a humectant and helps add texture to products. It can make your product thicker.
As a humectant, it helps draw moisture from the air to your skin. This helps your skin stay hydrated.
Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Glyceryl Stearate is made by reacting glycerin with stearic acid (typically sourced from plant oils like palm or coconut). It's an emulsifier, emollient, and mild occlusive.
Emulsifiers help ingredients like oil and water stay mixed so your formula stays nicely blended and uniform in texture.
This ingredient is typically used in concentrations between 1-10%. Studies have found it to be non-sensitizing, non-phototoxic, and non-photoallergenic.
A close cousin of this ingredient is Glyceryl Stearate SE ("self-emulsifying"). This just has a small amount of sodium or potassium stearate added so it can emulsify without a co-emulsifier.
Since this ingredient is an ester of a C18 fatty acid, it may not be fungal acne safe. The Malassezia yeast can potentially metabolize within the C11-C24 range.
Fun fact: The human body also creates Glyceryl Stearate naturally.
Peg-100 Stearate is an emollient and emulsifier. As an emollient, it helps keep skin soft by trapping moisture in. On the other hand, emulsifiers help prevent oil and water from separating in a product.
PEGS are a hydrophilic polyether compound . There are 100 ethylene oxide monomers in Peg-100 Stearate. Peg-100 Stearate is polyethylene glycol ester of stearic acid.
Phenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!).
It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome.
On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive.
Another perk of this ingredient is that it stays functional across a wide pH range (3-10).
You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own.
Typical use concentrations range from 0.3-1% depending on the formula, and this ingredient is capped at 1% int the EU.
Safety-wise, the fear mongering does not hold up to the evidence. The EU's Scientific Committee on Consumer Safety and FDA consider it safe as a preservative at up to 1%, including for children of all ages.
Adverse systemic effects only showed up in animal studies at exposures roughly 200x higher than what people get from cosmetics. And despite its very widespread use, this ingredient is a rare sensitizer and allergic reactions are uncommon.
Sodium Hyaluronate is the salt form of hyaluronic acid. It is a long sugar chain that is naturally found in your skin, joints, and connective tissue that maintains hydration and elasticity.
In skincare, it works as a humectant. It pulls water from the environment and deeper layers of skin and binds it to the surface.
Interestingly, the size of the molecule affects its behavior:
Some clinical evidence links low molecular weight versions to improved wrinkle depth, elasticity, anti-inflammatory effects, and barrier repair.
Many serums use a blend of both weights so you can get surface hydration plus longer-lasting and deeper effects.
You'll typically see concentrations between 0.1-2% for this ingredient.
Sodium Hydroxide is also known as lye or caustic soda. It is used to adjust the pH of products; many ingredients require a specific pH to be effective.
In small amounts, sodium hydroxide is considered safe to use. However, large amounts may cause chemical burns due to its high alkaline.
Your skin has a natural pH and acid mantle. This acid mantle helps prevent harmful bacteria from breaking through. The acid mantle also helps keep your skin hydrated.
"Alkaline" refers to a high pH level. A low pH level would be considered acidic.
Tocopheryl Acetate is a stable, shelf-friendly form of vitamin E.
Formulators love it because plain vitamin E oxidizes quickly once it hits air. This acetate version stays stable and resists going off, helping to extend a product's shelf life.
It's actually inactive on its own and works like a slow-release "storage" form; the enzymes in your skin called esterases gradually convert it into active vitamin E over time.
One in vivo study showed 5% of the acetate in the living layer of the epidermis converted to vitamin E after 5 days of application. This study also found the skin gained protection against UV damage even though the conversion was slow and small.
Once converted, vitamin E acts as a skin's main fat-soluble antioxidant that fights free radicals to protect skin from damage.
Topical vitamin E generally boosts the skin's photoprotection, and it reduced UV-damage in animal models.
This ingredient has some brightening potential but it's more of a prevention ingredient than spot-fader. Cell studies show it can slow down melanin production but it's worth noting that it's not the most powerful brightener out there.
Overall, it has a pretty solid safety profile and has been found to be non-irritating and non-comedogenic. Allergic reactions may happen but stay rare due to how widely the ingredient gets used.
The concentration will vary depending on the formula; industry data shows 0.1% in baby lotions, 3% in lipsticks, and 5% in foot powders. You can also find this ingredient at 100% in a pure vitamin E oil.
Most leave-on skincare keeps it at the lower end, often between 0.5-1%.
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!