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Endocare Renewal Retinol Intensive Serum 0.5% Pure Retinol Versus NeoStrata Skin Active Triple Therapy Lifting Serum

Endocare Renewal Retinol Intensive Serum 0.5% Pure Retinol Versus NeoStrata Skin Active Triple Therapy Lifting Serum This anti-aging serum is formulated around Niacinamide and Retinol to soften the look of wrinkles and refine skin texture. This anti-aging seru

By Peptide Skincare & Beauty Editorial TeamPublished

Endocare Renewal Retinol Intensive Serum 0.5% Pure Retinol Versus NeoStrata Skin Active Triple Therapy Lifting Serum

This anti-aging serum is formulated around Niacinamide and Retinol to soften the look of wrinkles and refine skin texture.

This anti-aging serum is formulated around Gluconolactone to soften the look of wrinkles and refine skin texture.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Cyclopentasiloxane

Caprylyl Methicone

C12-15 Alkyl Benzoate

Undecane

Dimethicone/Vinyl Dimethicone Crosspolymer

Trisiloxane

Dimethyl Isosorbide

PEG-7 Glyceryl Cocoate

Pentylene Glycol

Niacinamide

Tridecane

Sodium Hyaluronate Crosspolymer

PEG-12 Dimethicone

Methyl Methacrylate/Glycol Dimethacrylate Crosspolymer

Bisabolol

Retinol

Hydroxypinacolone Retinoate

Ascorbic Acid

Tocopheryl Acetate

Silica Silylate

Zea Mays Starch

Tetrahexyldecyl Ascorbate

Phenylpropanol

Polysorbate 20

Caprylyl Glycol

Propanediol

Silica

Dimethicone

Propyl Gallate

Disodium EDTA

BHT

Tocopherol

Cyclopentasiloxane, Caprylyl Methicone, C12-15 Alkyl Benzoate, Undecane, Dimethicone/Vinyl Dimethicone Crosspolymer, Trisiloxane, Dimethyl Isosorbide, PEG-7 Glyceryl Cocoate, Pentylene Glycol, Niacinamide, Tridecane, Sodium Hyaluronate Crosspolymer, PEG-12 Dimethicone, Methyl Methacrylate/Glycol Dimethacrylate Crosspolymer, Bisabolol, Retinol, Hydroxypinacolone Retinoate, Ascorbic Acid, Tocopheryl Acetate, Silica Silylate, Zea Mays Starch, Tetrahexyldecyl Ascorbate, Phenylpropanol, Polysorbate 20, Caprylyl Glycol, Propanediol, Silica, Dimethicone, Propyl Gallate, Disodium EDTA, BHT, Tocopherol

Water

PEG-8

Gluconolactone

1,2-Hexanediol

Glycerin

Polymethylsilsesquioxane

Acetyl Tyrosinamide

Cyclohexasiloxane

Hydrolyzed Sodium Hyaluronate

Dimethiconol

Biosaccharide Gum-1

Polyacrylate-13

Polyisobutene

Isopropyl Myristate

Sodium Sulfite

Ammonium Hydroxide

Xanthan Gum

Methyldihydrojasmonate

2,6-Dimethyl-7-Octen-2-Ol

Ethyl Acetoacetate

Methyl Benzodioxepinone

Phenoxyethanol

Chlorphenesin

CI 17200

CI 42090

Water, PEG-8, Gluconolactone, 1,2-Hexanediol, Cyclopentasiloxane, Glycerin, Pentylene Glycol, PEG-12 Dimethicone, Polymethylsilsesquioxane, Acetyl Tyrosinamide, Cyclohexasiloxane, Hydrolyzed Sodium Hyaluronate, Dimethiconol, Biosaccharide Gum-1, Polyacrylate-13, Polyisobutene, Isopropyl Myristate, Polysorbate 20, Sodium Sulfite, BHT, Ammonium Hydroxide, Caprylyl Glycol, Xanthan Gum, Methyldihydrojasmonate, 2,6-Dimethyl-7-Octen-2-Ol, Ethyl Acetoacetate, Methyl Benzodioxepinone, Phenoxyethanol, Chlorphenesin, CI 17200, CI 42090

Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

BHT is a synthetic antioxidant and preservative.

As an antioxidant, it helps your body fight off free-radicals. Free-radicals are molecules that may damage your skin cells.

As a preservative, it is used to stabilize products and prevent them from degrading. Specifically, BHT prevents degradation from oxidation.

The concerns related to BHT come from oral studies; this ingredient is currently allowed for use by both the FDA and EU.

However, it was recently restricted for use in the UK as of April 2024.

Caprylyl Glycol is a humectant, skin conditioner, emollient, and preservative booster derived from either caprylic acid or synthetically created.

Typical use levels vary from 0.3-1% as a preservative booster and go up to 2% to condition skin.

Because it is not a free-fatty acid, this ingredient is fungal acne safe (there's nothing for Malassezia to feed on).

Cyclopentasiloxane (D5) is a lightweight silicone that mostly acts as an emollient and solvent in cosmetics. Its the reason your products feel silky, fast-spreading, and non-greasy.

Since D5 is volatile, it does its thing and then evaporates off the skin quickly.

The safety profile of this ingredient is reassuring; the US CIR Expert Panel concluded D5 is safe as used in cosmetics and Health Canada concluded that D5 is not harmful to human health or the environment as currently used in cosmetics

There's a study that people mention about D5 in a rat study showing tumors. This study is related to long-term inhalation of high D5 levels.

Regulatory bodies have judged this study to be not applicable in topical skincare since skin absorption of D5 is very low and we're not really inhaling huge amounts of D5.

The only restriction for this ingredient is environmental. The European Chemicals Agency (ECHA) restricted D5 in wash-off cosmetics at or above 0.1% due to their persistence in water.

PEG-12 Dimethicone is a type of water-soluble silicone. It has skin conditioning and hydrating properties.

According to a manufacturer, this ingredient's stability is decreased by strong acid or alkali.

Pentylene Glycol (1,2-pentanediol) is a multitasking little diol with three main roles in a formula:

Research on alkanediols (the family pentylene glycol belongs to) show they work by disrupting microbial cell membranes. This disruption helps the primary preservative system in a product work more effectively at lower doses.

On the safety side, the Cosmetic Ingredient Review Expert Panel has concluded this ingredient to be safe as used in current cosmetic practices + concentrations.

Typical use levels in a formula run about 1-5%.

Polysorbate 20 is a gentle, water-soluble emulsifier and mild surfactant. It stops oil and water from separating to keep your formulas blended and stable.

It also acts as a mild penetration enhancer by helping active ingredients absorb slightly better.

The common safety discussion around this ingredient involves a manufacturing byproduct called 1,4-dioxane.

Trace amounts can form during production but the EU's Scientific Committee on Consumer Safety has concluded that levels at/below 10 ppm in finished products are safe (commercial products consistently fall within acceptable margins).

True allergic reactions are uncommon and the CIR Expert Panel has confirmed this ingredient to be safe as used in cosmetics.

Because it is derived from lauric acid, it may not be fungal acne safe.

Similar Comparisons

The reference edit

Ingredients, questions
& further reading.

Connected source records selected through this article’s public topic index.

01

Formula cabinet

Ingredients & structured notes

Ingredient index

Ingredients Explained

  1. 01Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
  2. 02So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
  3. 03You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!
  4. 04Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:
  5. 05Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.
  6. 06Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.
  7. 07Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
  8. 08Topically, glycerin does several things at once:
  9. 09Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
  10. 10Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
  11. 11This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
  12. 12Just know very high concentrations (>40%) can feel tacky in low humidity.
  13. 13Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
  14. 14Isopentyldiol is a synthetic solvent, humectant, and emollient.
  15. 15Humectants have the ability to attract and hold water while emollients create a thin film to prevent water from evaporating. This combination keeps your skin and hair soft and hydrated. Plus, isopentyldiol does not leave a sticky feeling behind.
  16. 16As a surfactant, isopentyldiol is a hydrotrope. Hydrotropes help surfactants (cleansing agents) dissolve into water.
  17. 17According to the manufacturer, using this ingredient with sorbitol boosts skin hydration and helps close cuticles of damaged hair.
  18. 18This ingredient is water-soluble.
  19. 191,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse.
  20. 20It is a:
Source · skinsort.com ⟶
02

Product index

Related product references

Product

Tosowoong Carnosine Lifting Serum

Tosowoong Carnosine Lifting Serum Tosowoong Carnosine Lifting Serum ingredients explained: Water, Butylene Glycol, 1,2-Hexanediol, Ethylhexyl Palmitate, Glycerin, Methyl Gluceth-20, Ammoniu…

Source: incidecoder.comView reference →
03

Comparison edit

Read side by side

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