Skin science article
Face Reality Skincare Antioxidant Peptide serum Versus SkinBetter Science Alto Defense Serum
Face Reality Skincare Antioxidant Peptide serum Versus SkinBetter Science Alto Defense Serum This anti-aging serum is formulated around Palmitoyl Tripeptide-38 to soften the look of wrinkles and refine skin texture. This calming serum is formulated around Glyc
Face Reality Skincare Antioxidant Peptide serum Versus SkinBetter Science Alto Defense Serum
This anti-aging serum is formulated around Palmitoyl Tripeptide-38 to soften the look of wrinkles and refine skin texture.
This calming serum is formulated around Glycyrrhiza Glabra Root Extract and Tetrahexyldecyl Ascorbate to calm redness and brighten dull-looking skin.
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Glycerin
Caprylic/Capric Triglyceride
Phenoxyethanol
Sclerotium Gum
Xanthan Gum
Polyglyceryl-4 Caprate
Benzyl Alcohol
Sodium Gluconate
Caprylhydroxamic Acid
Ethylhexylglycerin
Acetyl Tributyl Citrate
Methylglucoside Phosphate
Copper Lysinate/Prolinate
Hydroxypropyl Cyclodextrin
Pichia/Resveratrol Ferment Extract
Palmitoyl Tripeptide-38
Phenyl T-Butylnitrone
Water, Glycerin, Caprylic/Capric Triglyceride, Phenoxyethanol, Sclerotium Gum, Xanthan Gum, Polyglyceryl-4 Caprate, Benzyl Alcohol, Sodium Gluconate, Caprylhydroxamic Acid, Ethylhexylglycerin, Acetyl Tributyl Citrate, Methylglucoside Phosphate, Copper Lysinate/Prolinate, Hydroxypropyl Cyclodextrin, Pichia/Resveratrol Ferment Extract, Palmitoyl Tripeptide-38, Phenyl T-Butylnitrone
Butylene Glycol
Propanediol
Ethylhexyl Olivate
Cetearyl Alcohol
Chlorogenic Acids
Hydrolyzed Sodium Hyaluronate
Lauryl Lactate
Dimethyl Isosorbide
Glycyrrhiza Glabra Root Extract
Tetrahexyldecyl Ascorbate
Ergothioneine
Benzylidene Dimethoxydimethylindanone
Arabidopsis Thaliana Extract
Carnosine
Camellia Sinensis Leaf Extract
Vitis Vinifera Seed Extract
Theobroma Cacao Seed Extract
Curcuma Longa Root Extract
Olea Europaea Fruit Extract
Euterpe Oleracea Fruit Extract
Trifluoroacetyl Tripeptide-2
Buddleja Officinalis Flower Extract
Coffea Arabica Leaf Cell Extract
Crocus Sativus Leaf Cell Culture Extract
Superoxide Dismutase
Ubiquinone
Zingiber Officinale Root Extract
Ceramide NP
Ceramide AP
Ceramide EOP
Linoleic Acid
Linolenic Acid
Sea Whip Extract
Bisabolol
Tocopherol
Tocopheryl Acetate
Cholesterol
Phytosphingosine
Jojoba Esters
Sodium PCA
Pentylene Glycol
Methyl Gluceth-20
Helianthus Annuus Seed Wax
Acacia Decurrens Flower Wax
Lecithin
Sodium Lauroyl Lactylate
Dicetyl Phosphate
Propanediol Dicaprylate/Caprate
Polyglycerin-3
Ceteth-20 Phosphate
Diisostearyl Malate
Steareth-2
Acacia Senegal Gum
Carbomer
Acrylates/C10-30 Alkyl Acrylate Crosspolymer
Dextran
Sodium Hydroxide
Citric Acid
Disodium EDTA
Water, Butylene Glycol, Propanediol, Ethylhexyl Olivate, Cetearyl Alcohol, Chlorogenic Acids, Hydrolyzed Sodium Hyaluronate, Lauryl Lactate, Dimethyl Isosorbide, Glycyrrhiza Glabra Root Extract, Tetrahexyldecyl Ascorbate, Ergothioneine, Benzylidene Dimethoxydimethylindanone, Arabidopsis Thaliana Extract, Carnosine, Camellia Sinensis Leaf Extract, Vitis Vinifera Seed Extract, Theobroma Cacao Seed Extract, Curcuma Longa Root Extract, Olea Europaea Fruit Extract, Euterpe Oleracea Fruit Extract, Trifluoroacetyl Tripeptide-2, Buddleja Officinalis Flower Extract, Coffea Arabica Leaf Cell Extract, Crocus Sativus Leaf Cell Culture Extract, Superoxide Dismutase, Ubiquinone, Zingiber Officinale Root Extract, Ceramide NP, Ceramide AP, Ceramide EOP, Linoleic Acid, Linolenic Acid, Sea Whip Extract, Bisabolol, Tocopherol, Tocopheryl Acetate, Cholesterol, Phytosphingosine, Jojoba Esters, Sodium PCA, Pentylene Glycol, Methyl Gluceth-20, Glycerin, Helianthus Annuus Seed Wax, Acacia Decurrens Flower Wax, Lecithin, Sodium Lauroyl Lactylate, Dicetyl Phosphate, Propanediol Dicaprylate/Caprate, Polyglycerin-3, Ceteth-20 Phosphate, Diisostearyl Malate, Xanthan Gum, Steareth-2, Acacia Senegal Gum, Carbomer, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Dextran, Sodium Hydroxide, Citric Acid, Disodium EDTA, Ethylhexylglycerin, Phenoxyethanol
Alternatives
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Ethylhexylglycerin is created from glycerin. It is a multitasker ingredient that:
The CIR Expert Panel found minimal skin absorption or sensitization of any kind in a safety assessment. Though this ingredient is considered well-tolerated, a small number of cases of allergic dermatitis have been published since 2002. Just be sure to patch test if you are unsure.
Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations.
Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Phenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!).
It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome.
On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive.
Another perk of this ingredient is that it stays functional across a wide pH range (3-10).
You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own.
Typical use concentrations range from 0.3-1% depending on the formula, and this ingredient is capped at 1% int the EU.
Safety-wise, the fear mongering does not hold up to the evidence. The EU's Scientific Committee on Consumer Safety and FDA consider it safe as a preservative at up to 1%, including for children of all ages.
Adverse systemic effects only showed up in animal studies at exposures roughly 200x higher than what people get from cosmetics. And despite its very widespread use, this ingredient is a rare sensitizer and allergic reactions are uncommon.
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!
Xanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.
On the technical side of things, xanthan gum is a polysaccharide - a combination consisting of multiple sugar molecules bonded together.
Xanthan gum is a pretty common and great ingredient. It is a natural, non-toxic, non-irritating ingredient that is also commonly used in food products.