IntraCeuticals Collagen Serum Versus rhode Peptide Glazing Fluid

IntraCeuticals Collagen Serum Versus rhode Peptide Glazing Fluid

This anti-aging serum is formulated around Palmitoyl Oligopeptide and Palmitoyl Tetrapeptide-7 to soften the look of wrinkles and hydrate skin.

This barrier-repair serum is formulated around Sclerocarya Birrea Seed Oil and Niacinamide to strengthen the skin barrier and soften the look of wrinkles.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Water

Glycerin

Soluble Collagen

Sodium Hyaluronate

Anogeissus Leiocarpus Bark Extract

Palmitoyl Oligopeptide

Palmitoyl Tetrapeptide-7

Propanediol

Butylene Glycol

Vegetable Oil

1,2-Hexanediol

Caprylyl Glycol

Dicaprylyl Ether

Polyacrylate Crosspolymer-6

Polyglyceryl-2 Dipolyhydroxystearate

Lauryl Glucoside

Tetrasodium Glutamate Diacetate

Citric Acid

Dicaprylyl Carbonate

Glyceryl Oleate

Carbomer

Polysorbate 20

Sodium Benzoate

Water, Glycerin, Soluble Collagen, Sodium Hyaluronate, Anogeissus Leiocarpus Bark Extract, Palmitoyl Oligopeptide, Palmitoyl Tetrapeptide-7, Propanediol, Butylene Glycol, Vegetable Oil, 1,2-Hexanediol, Caprylyl Glycol, Dicaprylyl Ether, Polyacrylate Crosspolymer-6, Polyglyceryl-2 Dipolyhydroxystearate, Lauryl Glucoside, Tetrasodium Glutamate Diacetate, Citric Acid, Dicaprylyl Carbonate, Glyceryl Oleate, Carbomer, Polysorbate 20, Sodium Benzoate

Sclerocarya Birrea Seed Oil

Niacinamide

Tetradecane

Capryloyl Glycerin/Sebacic Acid Copolymer

Diheptyl Succinate

Benzyl Alcohol

Sucrose Palmitate

Hydroxyacetophenone

Acrylates/C10-30 Alkyl Acrylate Crosspolymer

Sodium Hydroxide

Disodium Phosphate

Sodium Phosphate

Dilauryl Thiodipropionate

Acetyl Hexapeptide-8

Water, Butylene Glycol, Glycerin, Sclerocarya Birrea Seed Oil, Niacinamide, Tetradecane, Capryloyl Glycerin/Sebacic Acid Copolymer, Diheptyl Succinate, Benzyl Alcohol, Glyceryl Oleate, Sucrose Palmitate, Hydroxyacetophenone, Carbomer, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Caprylyl Glycol, Sodium Hydroxide, Disodium Phosphate, Sodium Phosphate, Sodium Hyaluronate, Dilauryl Thiodipropionate, Acetyl Hexapeptide-8

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Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:

Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.

Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.

Caprylyl Glycol is a humectant, skin conditioner, emollient, and preservative booster derived from either caprylic acid or synthetically created.

Typical use levels vary from 0.3-1% as a preservative booster and go up to 2% to condition skin.

Because it is not a free-fatty acid, this ingredient is fungal acne safe (there's nothing for Malassezia to feed on).

Carbomer is a synthetic thickening and gelling agent. It's basically the ingredient that gives a lot of serums, gels, creams, and sunscreens their smooth, non-sticky texture.

Although legally permitted at very high levels, carbomers are normally used at concentrations below 1%.

It also needs to be neutralized to actually thicken, and because it is a large molecule, it doesn't really penetrate the skin barrier.

Allergy-wise, the risk is very low. Clinical studies show carbomers have low potential for skin irritation/sensitization even at concentrations up to 100%.

A 2024 UK study patch-tested 1,302 patients and found true allergy to the parent group of carbomer to be rare with no confirmed relevant reactions.

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Glyceryl Oleate is the monoester of glycerin and oleic acid. It is a skin-conditioning emollient that also helps form emulsions.

What makes glyceryl oleate special is its "re-fatting" effect.

When you wash your hair and skin with a surfactant-based cleanser, the surfactants grab onto everything. This includes your skin's natural lipids, or the fats that live in your skin barrier and sebum. Once you rinse these surfactants away, it leaves your skin feeling tight, dry, and clean (in a not-good way).

Re-fatting is essentially putting some of these lipids back. Glyceryl oleate deposits a thin layer of emollient lipids back on the skin or hair surface reduce some of the barrier damage.

Also, glyceryl oleate isn't a foreign molecule to your skin. It's chemically identical to something your skin already produces and manages naturally. This is why it tends to be well-tolerated with low risk of irritation.

Typical use levels range from 0.5-5%.

Glyceryl Oleate has a function of "perfuming" in the CosIng database. This just means that the ingredient has some scent character that can contribute to the product's overall smell.

The scent of this ingredient is described as "waxy".

As an ester of oleic acid, this ingredient may not be fungal acne safe. This is because oleic acid falls into the carbon-chain length that Malassezia can use as a substrate.

Sodium Hyaluronate is the salt form of hyaluronic acid. It is a long sugar chain that is naturally found in your skin, joints, and connective tissue that maintains hydration and elasticity.

In skincare, it works as a humectant. It pulls water from the environment and deeper layers of skin and binds it to the surface.

Interestingly, the size of the molecule affects its behavior:

Some clinical evidence links low molecular weight versions to improved wrinkle depth, elasticity, anti-inflammatory effects, and barrier repair.

Many serums use a blend of both weights so you can get surface hydration plus longer-lasting and deeper effects.

You'll typically see concentrations between 0.1-2% for this ingredient.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

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