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Is Clinical Cleansing Complex Versus PCA Skin BPO 5% Cleanser

Is Clinical Cleansing Complex Versus PCA Skin BPO 5% Cleanser This benzoyl peroxide foaming cleanser is formulated around Benzoyl Peroxide to clear breakouts and help reduce acne-causing bacteria. What's inside Key Ingredients Benefits Concerns Ingredients Sid

Is Clinical Cleansing Complex Versus PCA Skin BPO 5% Cleanser

This benzoyl peroxide foaming cleanser is formulated around Benzoyl Peroxide to clear breakouts and help reduce acne-causing bacteria.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Water

Disodium Laureth Sulfosuccinate

Cocamidopropyl Betaine

PEG-30 Glyceryl Cocoate

Glycerin

Propylene Glycol

Hydroxyethylcellulose

Salix Alba Bark Extract

Saccharum Officinarum Extract

Camellia Sinensis Leaf Extract

Chamomilla Recutita Flower Extract

Asiaticoside

Asiatic Acid

Madecassic Acid

Ascorbyl Palmitate

Phospholipids

Tocopheryl Acetate

Retinyl Palmitate

Iodopropynyl Butylcarbamate

Phenoxyethanol

Water, Disodium Laureth Sulfosuccinate, Cocamidopropyl Betaine, PEG-30 Glyceryl Cocoate, Glycerin, Propylene Glycol, Hydroxyethylcellulose, Salix Alba Bark Extract, Saccharum Officinarum Extract, Camellia Sinensis Leaf Extract, Chamomilla Recutita Flower Extract, Asiaticoside, Asiatic Acid, Madecassic Acid, Ascorbyl Palmitate, Phospholipids, Tocopheryl Acetate, Retinyl Palmitate, Iodopropynyl Butylcarbamate, Phenoxyethanol

Benzoyl Peroxide 5%

Gluconolactone

Sodium C14-16 Olefin Sulfonate

Aminomethyl Propanol

Acrylates/C10-30 Alkyl Acrylate Crosspolymer

Polyacrylate-13

Citrus Grandis Peel Oil

Polyisobutene

Caprylyl Glycol

Ethylhexylglycerin

Hexylene Glycol

Allantoin

Simmondsia Chinensis Seed Oil

Triticum Vulgare Germ Oil

Aloe Barbadensis Leaf Juice

Panthenol

Sodium PCA

Polysorbate 20

Butylene Glycol

Phytic Acid

Algae Extract

Anthemis Nobilis Flower Extract

Arnica Montana Flower Extract

Cucumis Sativus Fruit Extract

Vitis Vinifera Seed Extract

Benzoyl Peroxide 5%, Water, Gluconolactone, Sodium C14-16 Olefin Sulfonate, Aminomethyl Propanol, Glycerin, Cocamidopropyl Betaine, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Phenoxyethanol, Polyacrylate-13, Citrus Grandis Peel Oil, Polyisobutene, Caprylyl Glycol, Ethylhexylglycerin, Hexylene Glycol, Allantoin, Simmondsia Chinensis Seed Oil, Tocopheryl Acetate, Triticum Vulgare Germ Oil, Aloe Barbadensis Leaf Juice, Panthenol, Sodium PCA, Polysorbate 20, Butylene Glycol, Phytic Acid, Algae Extract, Anthemis Nobilis Flower Extract, Arnica Montana Flower Extract, Cucumis Sativus Fruit Extract, Vitis Vinifera Seed Extract

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Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Cocamidopropyl Betaine is a fatty acid created by mixing similar compounds in coconut oil and dimethylaminopropylamine, a compound with two amino groups.

This ingredient is a surfactant and cleanser. It helps gather the dirt, pollutants, and other impurities in your skin to be washed away. It also helps thicken a product and make the texture more creamy.

Being created from coconut oil means Cocamidopropyl Betaine is hydrating for the skin.

While Cocamidopropyl Betaine was believed to be an allergen, a study from 2012 disproved this. It found two compounds in unpure Cocamidopropyl Betaine to be the irritants: aminoamide and 3-dimethylaminopropylamine. High-grade and pure Cocamidopropyl Betaine did not induce allergic reactions during this study.

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Phenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!).

It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome.

On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive.

Another perk of this ingredient is that it stays functional across a wide pH range (3-10).

You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own.

Typical use concentrations range from 0.3-1% depending on the formula, and this ingredient is capped at 1% int the EU.

Safety-wise, the fear mongering does not hold up to the evidence. The EU's Scientific Committee on Consumer Safety and FDA consider it safe as a preservative at up to 1%, including for children of all ages.

Adverse systemic effects only showed up in animal studies at exposures roughly 200x higher than what people get from cosmetics. And despite its very widespread use, this ingredient is a rare sensitizer and allergic reactions are uncommon.

Tocopheryl Acetate is a stable, shelf-friendly form of vitamin E.

Formulators love it because plain vitamin E oxidizes quickly once it hits air. This acetate version stays stable and resists going off, helping to extend a product's shelf life.

It's actually inactive on its own and works like a slow-release "storage" form; the enzymes in your skin called esterases gradually convert it into active vitamin E over time.

One in vivo study showed 5% of the acetate in the living layer of the epidermis converted to vitamin E after 5 days of application. This study also found the skin gained protection against UV damage even though the conversion was slow and small.

Once converted, vitamin E acts as a skin's main fat-soluble antioxidant that fights free radicals to protect skin from damage.

Topical vitamin E generally boosts the skin's photoprotection, and it reduced UV-damage in animal models.

This ingredient has some brightening potential but it's more of a prevention ingredient than spot-fader. Cell studies show it can slow down melanin production but it's worth noting that it's not the most powerful brightener out there.

Overall, it has a pretty solid safety profile and has been found to be non-irritating and non-comedogenic. Allergic reactions may happen but stay rare due to how widely the ingredient gets used.

The concentration will vary depending on the formula; industry data shows 0.1% in baby lotions, 3% in lipsticks, and 5% in foot powders. You can also find this ingredient at 100% in a pure vitamin E oil.

Most leave-on skincare keeps it at the lower end, often between 0.5-1%.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

Similar Comparisons

The reference edit

Ingredients, questions
& further reading.

Connected source records selected through this article’s public topic index.

01

Formula cabinet

Ingredients & structured notes

Ingredient index

Ingredients Explained

  1. 01These ingredients are found in both products.
  2. 02Ingredients higher up in an ingredient list are typically present in a larger amount.
  3. 03Caprylyl Glycol is a humectant, skin conditioner, emollient, and preservative booster derived from either caprylic acid or synthetically created.
  4. 04Typical use levels vary from 0.3-1% as a preservative booster and go up to 2% to condition skin.
  5. 05Because it is not a free-fatty acid, this ingredient is fungal acne safe (there's nothing for Malassezia to feed on).
  6. 06Carbomer is a synthetic thickening and gelling agent. It's basically the ingredient that gives a lot of serums, gels, creams, and sunscreens their smooth, non-sticky texture.
  7. 07Although legally permitted at very high levels, carbomers are normally used at concentrations below 1%.
  8. 08It also needs to be neutralized to actually thicken, and because it is a large molecule, it doesn't really penetrate the skin barrier.
  9. 09Allergy-wise, the risk is very low. Clinical studies show carbomers have low potential for skin irritation/sensitization even at concentrations up to 100%.
  10. 10A 2024 UK study patch-tested 1,302 patients and found true allergy to the parent group of carbomer to be rare with no confirmed relevant reactions.
  11. 11Ceramide AP is is a skin-identical lipid that mimics what your skin already makes naturally. Ceramides help maintain epidermal integrity and barrier function.
  12. 12You'll often see this ingredient paired with other ceramides (like ceramide NP), cholesterol, or fatty acids because this combination best mimics the natural lipid mix your skin already has.
  13. 13The skin's ability to produce ceramides gets disrupted in skin conditions like eczema. This in turn weakens the skin barrier and applying ceramides topically has been shown to replenish what's been lost to restore barrier function.
  14. 14Most of the studies with Ceramide AP test it as part of a multi-ceramide complex; studies reinforce ceramide AP's role in rebalancing ceramides in skin and improving skin hydration.
  15. 15Ceramide EOP is formally known as Ceramide 1.
  16. 16It is naturally found in skin and part of the intercellular "mortar" holding everything together in your outermost layer.
  17. 17EOP stands for a linked Ester fatty acid, a linked Omega hydroxy fatty acid, and the Phytosphingosine base.
  18. 18What makes Ceramide EOP special is its ultra-long fatty acid chain; this unique structure allows it to bridge the lipid layers in your skin barrier to prevent water loss (something no other ceramide can do).
  19. 19Low levels of Ceramide EOP have been found in people with eczema and psoriasis.
  20. 20Using it together with other ceramides, cholesterol, and linoleic acid have been shown to meaningfully improve hydration and reduce water loss.
Source · skinsort.com
02

Product index

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03

Comparison edit

Read side by side