Peptide Skincare & BeautySkin science and ingredient guides

Skin science article

Is Clinical Hydra-Cool Serum Versus PCA Skin Hyaluronic Acid Boosting Serum

Is Clinical Hydra-Cool Serum Versus PCA Skin Hyaluronic Acid Boosting Serum This hydrating serum is formulated around Sodium Hyaluronate and Asiaticoside to hydrate skin and calm redness. This hydrating serum is formulated around Niacinamide and Sodium Hyaluro

Is Clinical Hydra-Cool Serum Versus PCA Skin Hyaluronic Acid Boosting Serum

This hydrating serum is formulated around Sodium Hyaluronate and Asiaticoside to hydrate skin and calm redness.

This hydrating serum is formulated around Niacinamide and Sodium Hyaluronate to hydrate skin and strengthen the skin barrier.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Water

Sodium Hyaluronate

Pantothenic Acid

Pentylene Glycol

Menthol

Phenoxyethanol

Asiaticoside

Polyporus Umbellatus Extract

Asiatic Acid

Madecassic Acid

CI 42090

Water, Sodium Hyaluronate, Pantothenic Acid, Pentylene Glycol, Menthol, Phenoxyethanol, Asiaticoside, Polyporus Umbellatus Extract, Asiatic Acid, Madecassic Acid, CI 42090

Propanediol

Glycerin

Niacinamide

Dimethicone

Hydrolyzed Yeast Extract

Polyglyceryl-3 Beeswax

Coconut Alkanes

Isododecane

Jojoba Esters

Dimethicone Crosspolymer

Polysilicone-11

Sodium Benzoate

Carbomer

Xanthan Gum

Hydrolyzed Hyaluronic Acid

Cetyl Alcohol

Polyglyceryl-6 Distearate

Sodium Lauroyl Lactylate

Disodium Acetyl Glucosamine Phosphate

Hydrolyzed Glycosaminoglycans

Ethylhexylglycerin

Sodium Hydroxide

Hexylene Glycol

Polygonum Bistorta Root Extract

Cetyl Hydroxyethylcellulose

Rosmarinus Officinalis Leaf Oil

Aroma

Polyglucuronic Acid

Ceramide NP

Hyaluronic Acid

Sodium Carrageenan

Ceramide AP

Phytosphingosine

Caprylyl Glycol

Cholesterol

Lecithin

Maris Sal

Ceramide EOP

Water, Propanediol, Glycerin, Niacinamide, Dimethicone, Hydrolyzed Yeast Extract, Polyglyceryl-3 Beeswax, Coconut Alkanes, Phenoxyethanol, Isododecane, Jojoba Esters, Dimethicone Crosspolymer, Polysilicone-11, Sodium Hyaluronate, Sodium Benzoate, Carbomer, Xanthan Gum, Hydrolyzed Hyaluronic Acid, Cetyl Alcohol, Polyglyceryl-6 Distearate, Sodium Lauroyl Lactylate, Disodium Acetyl Glucosamine Phosphate, Hydrolyzed Glycosaminoglycans, Ethylhexylglycerin, Sodium Hydroxide, Hexylene Glycol, Polygonum Bistorta Root Extract, Cetyl Hydroxyethylcellulose, Rosmarinus Officinalis Leaf Oil, Aroma, Polyglucuronic Acid, Ceramide NP, Hyaluronic Acid, Sodium Carrageenan, Ceramide AP, Phytosphingosine, Caprylyl Glycol, Cholesterol, Lecithin, Maris Sal, Ceramide EOP

Reviews

Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Phenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!).

It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome.

On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive.

Another perk of this ingredient is that it stays functional across a wide pH range (3-10).

You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own.

Typical use concentrations range from 0.3-1% depending on the formula, and this ingredient is capped at 1% int the EU.

Safety-wise, the fear mongering does not hold up to the evidence. The EU's Scientific Committee on Consumer Safety and FDA consider it safe as a preservative at up to 1%, including for children of all ages.

Adverse systemic effects only showed up in animal studies at exposures roughly 200x higher than what people get from cosmetics. And despite its very widespread use, this ingredient is a rare sensitizer and allergic reactions are uncommon.

Sodium Hyaluronate is the salt form of hyaluronic acid. It is a long sugar chain that is naturally found in your skin, joints, and connective tissue that maintains hydration and elasticity.

In skincare, it works as a humectant. It pulls water from the environment and deeper layers of skin and binds it to the surface.

Interestingly, the size of the molecule affects its behavior:

Some clinical evidence links low molecular weight versions to improved wrinkle depth, elasticity, anti-inflammatory effects, and barrier repair.

Many serums use a blend of both weights so you can get surface hydration plus longer-lasting and deeper effects.

You'll typically see concentrations between 0.1-2% for this ingredient.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

Similar Comparisons

The reference edit

Ingredients, questions
& further reading.

Connected source records selected through this article’s public topic index.

01

Formula cabinet

Ingredients & structured notes

Ingredient index

Ingredients Side-by-side

  1. 01Water
  2. 02Sodium Hyaluronate
  3. 03Glycerin
  4. 04Glycereth-26
  5. 05Dimethicone
  6. 06Bis-PEG-18 Methyl Ether Dimethyl Silane
  7. 07Malpighia Glabra Fruit Extract
  8. 08Portulaca Oleracea Extract
  9. 09Vaccinium Angustifolium Fruit Extract
  10. 10Tocopheryl Acetate
  11. 11Hibiscus Sabdariffa Flower Extract
  12. 12PEG-11 Methyl Ether Dimethicone
  13. 13Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer
  14. 14Ethylhexyl Isononanoate
  15. 15PEG-40 Hydrogenated Castor Oil
  16. 16PPG-26-Buteth-26
  17. 17Caprylyl Glycol
  18. 18Carbomer
  19. 19Triethanolamine
  20. 20Ethylhexylglycerin
Source · skinsort.com
02

Product index

Related product references

Product

PCA Skin Pore Cleansing Gel

PCA Skin Pore Cleansing Gel PCA Skin Pore Cleansing Gel ingredients explained: Water/Aqua/Eau, Alcohol, Mandelic Acid, Isopentyldiol, Pentylene Glycol, Butylene Glycol, Polyglyceryl-10 Diol…

Source: incidecoder.comView reference →

Product

PCA Skin Clinicalm™ 1%

PCA Skin Clinicalm™ 1% PCA Skin Clinicalm™ 1% ingredients explained: Hydrocortisone (1%), Water, Glycerin, Caprylic/Capric Triglyceride, Alcohol Denat, Cetearyl Olivate, Squalane, Olea Euro…

Source: incidecoder.comView reference →

Product

PCA Skin Pro-max Age Renewal

PCA Skin Pro-max Age Renewal PCA Skin Pro-max Age Renewal ingredients explained: Water, Polysilicone-11, Propanediol, Glycerin, Butylene Glycol, PPG-3 Benzyl Ether Myristate, Polysorbate 20…

Source: incidecoder.comView reference →
03

Comparison edit

Read side by side