L300 Pro-Retinol Firming Eye & Lip Cream Versus Paula's Choice Ceramide-Enriched Firming Eye Cream

L300 Pro-Retinol Firming Eye & Lip Cream Versus Paula's Choice Ceramide-Enriched Firming Eye Cream

This anti-aging eye moisturizer is formulated around Retinyl Palmitate and Acetyl Tetrapeptide-9 to soften the look of wrinkles and strengthen the skin barrier.

This anti-aging eye moisturizer is formulated around Ceramide Ns and Palmitoyl Tripeptide-5 to soften the look of wrinkles and strengthen the skin barrier.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Water

Propanediol

Caprylic/Capric Triglyceride

Coco-Caprylate/Caprate

Sorbitan Stearate

Triheptanoin

Glyceryl Stearate

Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer

Oryza Sativa Starch

Pentaerythrityl Distearate

Squalene

Avena Sativa Kernel Oil

Retinyl Palmitate

Acetyl Tetrapeptide-9

Acetyl Tetrapeptide-11

Laminaria Ochroleuca Extract

Glycerin

Ceramide NP

Ceramide Ns

Ceramide AP

Ceramide EOP

Ceramide Eos

Centella Asiatica Extract

Polygonum Cuspidatum Root Extract

Scutellaria Baicalensis Root Extract

Camellia Sinensis Leaf Extract

Chamomilla Recutita Flower Extract

Glycyrrhiza Glabra Root Extract

Rosmarinus Officinalis Leaf Extract

Allantoin

Tocopherol

Cholesterol

Caprooyl Phytosphingosine

Caprooyl Sphingosine

Dimethyl Isosorbide

Polysorbate 20

Butylene Glycol

Polysorbate 60

Sucrose Cocoate

Ceteareth-25

Glycine Soja Oil

Sorbitan Isostearate

Cetyl Alcohol

Beta-Sitosterol

Behenic Acid

Lactic Acid

Ascorbyl Palmitate

Tetrasodium Glutamate Diacetate

Phenoxyethanol

Sodium Benzoate

Potassium Sorbate

Caprylyl Glycol

Ethylhexylglycerin

Water, Propanediol, Caprylic/Capric Triglyceride, Coco-Caprylate/Caprate, Sorbitan Stearate, Triheptanoin, Glyceryl Stearate, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Oryza Sativa Starch, Pentaerythrityl Distearate, Squalene, Avena Sativa Kernel Oil, Retinyl Palmitate, Acetyl Tetrapeptide-9, Acetyl Tetrapeptide-11, Laminaria Ochroleuca Extract, Glycerin, Ceramide NP, Ceramide Ns, Ceramide AP, Ceramide EOP, Ceramide Eos, Centella Asiatica Extract, Polygonum Cuspidatum Root Extract, Scutellaria Baicalensis Root Extract, Camellia Sinensis Leaf Extract, Chamomilla Recutita Flower Extract, Glycyrrhiza Glabra Root Extract, Rosmarinus Officinalis Leaf Extract, Allantoin, Tocopherol, Cholesterol, Caprooyl Phytosphingosine, Caprooyl Sphingosine, Dimethyl Isosorbide, Polysorbate 20, Butylene Glycol, Polysorbate 60, Sucrose Cocoate, Ceteareth-25, Glycine Soja Oil, Sorbitan Isostearate, Cetyl Alcohol, Beta-Sitosterol, Behenic Acid, Lactic Acid, Ascorbyl Palmitate, Tetrasodium Glutamate Diacetate, Phenoxyethanol, Sodium Benzoate, Potassium Sorbate, Caprylyl Glycol, Ethylhexylglycerin

Neopentyl Glycol Diheptanoate

PEG-100 Stearate

Ammonium Acryloyldimethyltaurate/Vp Copolymer

Ascorbyl Glucoside

Potassium Cetyl Phosphate

Sodium Ascorbyl Phosphate

Bis-Diglyceryl Polyacyladipate-2

Polyglyceryl-10 Dioleate

Tetrahexyldecyl Ascorbate

Palmitoyl Tripeptide-5

Acetyl Tetrapeptide-5

Squalane

Retinol

Vitis Vinifera Seed Extract

Punica Granatum Fruit Extract

Dunaliella Salina Extract

Pongamia Glabra Seed Oil

Tocopheryl Acetate

Bisabolol

Carnosine

Panthenol

Sodium PCA

Pullulan

Glyceryl Ascorbate

Dimethicone

Sodium Citrate

Sodium Polyacrylate

Ethylhexyl Stearate

Sodium Hydroxide

Trideceth-6

Propyl Gallate

Disodium EDTA

Mica

Chlorphenesin

Water, Neopentyl Glycol Diheptanoate, Cetyl Alcohol, Butylene Glycol, Glycerin, Glyceryl Stearate, PEG-100 Stearate, Ammonium Acryloyldimethyltaurate/Vp Copolymer, Ascorbyl Glucoside, Potassium Cetyl Phosphate, Sodium Ascorbyl Phosphate, Bis-Diglyceryl Polyacyladipate-2, Polyglyceryl-10 Dioleate, Tetrahexyldecyl Ascorbate, Ceramide Ns, Ceramide EOP, Ceramide AP, Ceramide Eos, Ceramide NP, Palmitoyl Tripeptide-5, Acetyl Tetrapeptide-5, Caprooyl Phytosphingosine, Caprooyl Sphingosine, Cholesterol, Squalane, Retinol, Vitis Vinifera Seed Extract, Glycyrrhiza Glabra Root Extract, Punica Granatum Fruit Extract, Dunaliella Salina Extract, Pongamia Glabra Seed Oil, Tocopheryl Acetate, Allantoin, Bisabolol, Carnosine, Panthenol, Sodium PCA, Pullulan, Glyceryl Ascorbate, Behenic Acid, Dimethicone, Sodium Citrate, Sodium Polyacrylate, Caprylyl Glycol, Ethylhexyl Stearate, Ceteareth-25, Sodium Hydroxide, Trideceth-6, Propyl Gallate, Polysorbate 20, Disodium EDTA, Mica, Phenoxyethanol, Chlorphenesin, Sodium Benzoate

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Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Allantoin is a soothing ingredient known for its protective and moisturizing properties; it's basically a quiet workhorse ingredient you can find in a huge range of cosmetics.

Though it can be derived from the comfrey plant, allantoin is produced synthetically for cosmetic products to ensure purity.

Research shows it can encourage your skin cells to turn over and renew by stimulating keratinocyte and fibroblast proliferation.

It also has mild keratolytic properties to help loosen and shed dead skin cells without being harsh.

Studies also suggest allantoin can help calm inflammation by dialing down some of the chemical signals your skin sends out when it is irritated.

This ingredient is typically used in the 0.1-0.5% range, and the FDA recognizes it as a skin protectant in OTC products up to 2%.

Overall, allantoin is a wonderful addition to most routines; it is stable across a wide pH range (~4-8), works well with other ingredients, and is considered non-sensitizing/non-irritating.

Fun fact: Allantoin is naturally occurring in comfrey root, beets, chamomile, and wheat sprouts. Our bodies even produce it as a byproduct of uric acid metabolism.

Behenic acid is a long-chain fatty acid with 22 carbon atoms (C22) that is naturally found in moringa, rapeseed, and peanut oil.

In skincare, it's about as drama-free as ingredients come. It acts primarily as a texture enhancer, thickener, and opacifying agent that gives richness and viscosity to formulas.

On skin, it forms a protective, emollient layer that helps with moisture retention and contributes to barrier integrity.

In vitro studies on genotoxicity have come back negative and this ingredient is well-tolerated. Typical use concentrations range from 0.024%-22%.

This ingredient may not be fungal acne safe because Behenic acid falls within the C11-24 fatty acid range capable of supporting Malassezia growth.

Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:

Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.

Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.

This ceramide helps condition and moisturize skin.

It is created by reacting caproic acid and phytosphingosine, two fatty acids.

Ceramides work to improve hydration from within. Their lipophilic trait means they are likely to be absorbed into skin but expected to remain in the epidermis (the outer layer of skin).

We don't have a description for Caprooyl Sphingosine yet.

Caprylyl Glycol is a humectant, skin conditioner, emollient, and preservative booster derived from either caprylic acid or synthetically created.

Typical use levels vary from 0.3-1% as a preservative booster and go up to 2% to condition skin.

Because it is not a free-fatty acid, this ingredient is fungal acne safe (there's nothing for Malassezia to feed on).

Ceramide AP is is a skin-identical lipid that mimics what your skin already makes naturally. Ceramides help maintain epidermal integrity and barrier function.

You'll often see this ingredient paired with other ceramides (like ceramide NP), cholesterol, or fatty acids because this combination best mimics the natural lipid mix your skin already has.

The skin's ability to produce ceramides gets disrupted in skin conditions like eczema. This in turn weakens the skin barrier and applying ceramides topically has been shown to replenish what's been lost to restore barrier function.

Most of the studies with Ceramide AP test it as part of a multi-ceramide complex; studies reinforce ceramide AP's role in rebalancing ceramides in skin and improving skin hydration.

Ceramide EOP is formally known as Ceramide 1.

It is naturally found in skin and part of the intercellular "mortar" holding everything together in your outermost layer.

EOP stands for a linked Ester fatty acid, a linked Omega hydroxy fatty acid, and the Phytosphingosine base.

What makes Ceramide EOP special is its ultra-long fatty acid chain; this unique structure allows it to bridge the lipid layers in your skin barrier to prevent water loss (something no other ceramide can do).

Low levels of Ceramide EOP have been found in people with eczema and psoriasis.

Using it together with other ceramides, cholesterol, and linoleic acid have been shown to meaningfully improve hydration and reduce water loss.

In one clinical study, a regimen using Ceramide EOP, NP, and AP led to significant symptom improvements in patients with eczema, psoriasis, and dry skin in just 4 weeks.

You'll usually see concentrations between 0.1-0.5% in formulations. Overall, this is a well-tolerated and safe ingredient for cosmetic use.

Ceramide EOS is a type of Ceramide.

Ceramides are intercellular lipids naturally found in our skin that bonds dead skin cells together to create a barrier. They are known for their ability to hold water and thus are a great ingredient for dry skin.

Ceramide EOS is a synthetic N-acylated sphingolipid consisting of Sphingosine having the D-erythro structure linked to an esterified omega-hydroxy saturated or unsaturated fatty acid

Ceramide NP (formerly known as Ceramide 3) is one of the skin's naturally occurring lipids.

Since ceramides are the major lipid components of the skin, they are crucial for maintaining skin barrier and hydration. Ceramide NP most closely mirrors the dominant kind in human skin amongst ceramide subtypes.

This ceramide works by slotting into gaps within the stratum corneum's lipid matrix to limit trans-epidermal water loss (TEWL) and shield the skin against external irritants.

A study with 312 patients found that using a ceramide-containing routine for 4 weeks reduced the severity of atopic dermatitis by over 61%.

Another clinical study in subjects aged 60 and older found that a ceramide body wash and moisturizer improved skin dryness and itchy skin in 15 days.

Overall, ceramides are considered non-irritating and safety tests have found little to no observable adverse effects from using this ingredient.

Ceramide NP is usually sourced from plants (like soybean or rice bran), or produced synthetically.

Ceramide NS is formally known as Ceramide 2. It is one of the major ceramides in the stratum corneum (outermost layer of skin) plays a role in forming a protective barrier.

Due to its structure, skin lipids can be packed tightly and in turn, this strengthens the barrier and reduces water loss.

Studies show conditions like atopic dermatitis can worsen when ceramide NS levels are low.

Ceteareth-25 comes from Cetearyl Alcohol. (And Cetearyl Alcohol is created from cetyl alcohol and stearyl alcohol.

This ingredient is a fatty alcohol used as an emulsifier and surfactant. As an emulsifier, it helps oil mix with water.

Like cetearyl alcohol, Ceteareth-25 can help thicken and create a gel-like consistency.

Cetyl Alcohol is a fatty alcohol. Fatty Alcohols are most often used as an emollient or to thicken a product.

Its main roles are:

Though it has "alcohol" in the name, it is not related to denatured alcohol or ethyl alcohol.

The FDA allows products labeled "alcohol-free" to have fatty alcohols.

This ingredient may not be fungal acne safe. It is a primary fatty alcohol with a chain length above 12 carbons. A study from 2019 show Malassezia can feed on fatty alcohols in this range, so it may trigger fungal acne in those prone to it.

Cholesterol is a lipid that is naturally found in human skin and is one of the three key components of your skin barrier. In skincare, it is an emollient and barrier-repairing ingredient.

It works by fitting directly into the lipid layers of skin to help restore structure and reduce transepidermal water loss (TEWL).

This is a great ingredient for dry, compromised, or aging skin; our skin starts to produce less cholesterol with age.

Research shows cholesterol works best in combination with ceramides and fatty acids, the other two major components in your skin barrier.

Cholesterol is also a well-establish penetration enhancer and can help other actives absorb more effectively.

Cosmetic-grade cholesterol is usually derived from lanolin but plant and synthetic options also exist. We recommend reaching out to the brand if you have questions about their source of cholesterol.

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Glyceryl Stearate is made by reacting glycerin with stearic acid (typically sourced from plant oils like palm or coconut). It's an emulsifier, emollient, and mild occlusive.

Emulsifiers help ingredients like oil and water stay mixed so your formula stays nicely blended and uniform in texture.

This ingredient is typically used in concentrations between 1-10%. Studies have found it to be non-sensitizing, non-phototoxic, and non-photoallergenic.

A close cousin of this ingredient is Glyceryl Stearate SE ("self-emulsifying"). This just has a small amount of sodium or potassium stearate added so it can emulsify without a co-emulsifier.

Since this ingredient is an ester of a C18 fatty acid, it may not be fungal acne safe. The Malassezia yeast can potentially metabolize within the C11-C24 range.

Fun fact: The human body also creates Glyceryl Stearate naturally.

Glycyrrhiza Glabra Root Extract is an extract of the roots of Licorice. It has been found to have several benefits such as skin hydrating, conditioning, and soothing.

One component, glabridin, has extra potent antioxidant and soothing properties. It has also been found to block pigmentation from UVB rays in guinea pigs.

Licorice Root also contains a flavonoid. Flavonoids are a natural substance from in plants. Flavonoids also have antioxidant properties.

Another component, glycyrrhizin, has been found to have anti-inflammatory and antimicrobial benefits. This may make licorice root extract effective at treating acne. However, more research is needed to support this.

Liquiritin is one of the flavone compounds found in licorice. It has been found to help lighten skin by preventing tyrosinase from reacting with tyrosine. When the two react, protein is converted to melanin. Melanin is the substance in your body that gives your features pigmentation.

Phenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!).

It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome.

On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive.

Another perk of this ingredient is that it stays functional across a wide pH range (3-10).

You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own.

Typical use concentrations range from 0.3-1% depending on the formula, and this ingredient is capped at 1% int the EU.

Safety-wise, the fear mongering does not hold up to the evidence. The EU's Scientific Committee on Consumer Safety and FDA consider it safe as a preservative at up to 1%, including for children of all ages.

Adverse systemic effects only showed up in animal studies at exposures roughly 200x higher than what people get from cosmetics. And despite its very widespread use, this ingredient is a rare sensitizer and allergic reactions are uncommon.

Polysorbate 20 is a gentle, water-soluble emulsifier and mild surfactant. It stops oil and water from separating to keep your formulas blended and stable.

It also acts as a mild penetration enhancer by helping active ingredients absorb slightly better.

The common safety discussion around this ingredient involves a manufacturing byproduct called 1,4-dioxane.

Trace amounts can form during production but the EU's Scientific Committee on Consumer Safety has concluded that levels at/below 10 ppm in finished products are safe (commercial products consistently fall within acceptable margins).

True allergic reactions are uncommon and the CIR Expert Panel has confirmed this ingredient to be safe as used in cosmetics.

Because it is derived from lauric acid, it may not be fungal acne safe.

Sodium Benzoate is a preservative. It's used in both cosmetic and food products to inhibit the growth of mold and bacteria. It is typically produced synthetically.

Both the US FDA and EU Health Committee have approved the use of sodium benzoate. In the US, levels of 0.1% (of the total product) are allowed.

Sodium benzoate works as a preservative by inhibiting the growth of bacteria inside of cells. It prevents the cell from fermenting a type of sugar using an enzyme called phosphofructokinase.

It is the salt of benzoic acid. Foods containing sodium benzoate include soda, salad dressings, condiments, fruit juices, wines, and snack foods.

Studies for using ascorbic acid and sodium benzoate in cosmetics are lacking, especially in skincare routines with multiple steps.

We always recommend speaking with a professional, such as a dermatologist, if you have any concerns.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

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