La Mer The Concentrate Versus SkinMedica TNS® Advanced+ Serum

La Mer The Concentrate Versus SkinMedica TNS® Advanced+ Serum

This calming serum is formulated around Laminaria Ochroleuca Extract and Linoleic Acid to calm redness and strengthen the skin barrier.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Cyclopentasiloxane

Algae Extract

Glycerin

Dimethicone

Polysilicone-11

Isononyl Isononanoate

Dimethicone/PEG-10/15 Crosspolymer

Cyclohexasiloxane

Sesamum Indicum Seed Oil

Medicago Sativa Seed Powder

Helianthus Annuus Seedcake

Prunus Amygdalus Dulcis Seed Meal

Eucalyptus Globulus Leaf Oil

Sodium Gluconate

Copper Gluconate

Calcium Gluconate

Magnesium Gluconate

Zinc Gluconate

Tocopheryl Succinate

Niacin

Sesamum Indicum Seed Powder

Water

Dimethicone Crosspolymer

Laminaria Ochroleuca Extract

Triticum Vulgare Flour Lipids

Citrus Aurantifolia Peel Extract

Crithmum Maritimum Extract

Alteromonas Ferment Extract

Chlorella Vulgaris Extract

Faex Extract

Cholesterol

Linoleic Acid

Tocopherol

Tetraacetylphytosphingosine

Caprylic/Capric Triglyceride

Rosmarinus Officinalis Leaf Oil

Ocimum Basilicum Oil

Lavandula Angustifolia Oil

Lavandula Hybrida Oil

Dipropylene Glycol

Alcohol Denat.

Sodium Citrate

Parfum

Eugenol

Limonene

Linalool

BHT

Phenoxyethanol

Potassium Sorbate

Cyclopentasiloxane, Algae Extract, Glycerin, Dimethicone, Polysilicone-11, Isononyl Isononanoate, Dimethicone/PEG-10/15 Crosspolymer, Cyclohexasiloxane, Sesamum Indicum Seed Oil, Medicago Sativa Seed Powder, Helianthus Annuus Seedcake, Prunus Amygdalus Dulcis Seed Meal, Eucalyptus Globulus Leaf Oil, Sodium Gluconate, Copper Gluconate, Calcium Gluconate, Magnesium Gluconate, Zinc Gluconate, Tocopheryl Succinate, Niacin, Sesamum Indicum Seed Powder, Water, Dimethicone Crosspolymer, Laminaria Ochroleuca Extract, Triticum Vulgare Flour Lipids, Citrus Aurantifolia Peel Extract, Crithmum Maritimum Extract, Alteromonas Ferment Extract, Chlorella Vulgaris Extract, Faex Extract, Cholesterol, Linoleic Acid, Tocopherol, Tetraacetylphytosphingosine, Caprylic/Capric Triglyceride, Rosmarinus Officinalis Leaf Oil, Ocimum Basilicum Oil, Lavandula Angustifolia Oil, Lavandula Hybrida Oil, Dipropylene Glycol, Alcohol Denat., Sodium Citrate, Parfum, Eugenol, Limonene, Linalool, BHT, Phenoxyethanol, Potassium Sorbate

Pentylene Glycol

Human Neonatal Fibroblast Conditioned Media

Glycereth-7 Triacetate

Shea Butter Ethyl Esters

Ethoxydiglycol

Lactococcus Ferment Lysate

Whey Protein

Saccharide Isomerate

Dimer Tripeptide-43

Vitis Vinifera Flower Cell Extract

Pyrus Malus Fruit Extract

Hydroxyacetophenone

Tocopheryl Acetate

Propanediol

Xanthan Gum

Polyacrylate Crosspolymer-6

Polyacrylate-13

Polyisobutene

Sclerotium Gum

PEG-12 Dimethicone

Lecithin

Pullulan

Butylene Glycol

Polysorbate 20

Aminomethyl Propanol

Disodium EDTA

Ethylhexylglycerin

Water, Pentylene Glycol, Human Neonatal Fibroblast Conditioned Media, Glycereth-7 Triacetate, Shea Butter Ethyl Esters, Glycerin, Ethoxydiglycol, Lactococcus Ferment Lysate, Whey Protein, Chlorella Vulgaris Extract, Saccharide Isomerate, Dimer Tripeptide-43, Vitis Vinifera Flower Cell Extract, Pyrus Malus Fruit Extract, Hydroxyacetophenone, Tocopheryl Acetate, Propanediol, Xanthan Gum, Polyacrylate Crosspolymer-6, Polyacrylate-13, Polyisobutene, Sclerotium Gum, PEG-12 Dimethicone, Lecithin, Pullulan, Butylene Glycol, Sodium Citrate, Polysorbate 20, Aminomethyl Propanol, Disodium EDTA, Phenoxyethanol, Ethylhexylglycerin

Reviews

Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Chlorella Vulgaris Extract comes from a green microalga. It is hydrating and contains antioxidants.

Studies also show Chlorella Vulgaris may help in rebuilding collagen and elastin. This ingredient is made up of lipids, carbohydrates, and chlorophyll.

Fun fact: This ingredient is commonly used as food additive in Japan.

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Phenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!).

It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome.

On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive.

Another perk of this ingredient is that it stays functional across a wide pH range (3-10).

You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own.

Typical use concentrations range from 0.3-1% depending on the formula, and this ingredient is capped at 1% int the EU.

Safety-wise, the fear mongering does not hold up to the evidence. The EU's Scientific Committee on Consumer Safety and FDA consider it safe as a preservative at up to 1%, including for children of all ages.

Adverse systemic effects only showed up in animal studies at exposures roughly 200x higher than what people get from cosmetics. And despite its very widespread use, this ingredient is a rare sensitizer and allergic reactions are uncommon.

Sodium Citrate is the sodium salts of citric acid. In skincare, it is used to alter pH levels and acts as a preservative.

Its main functions are to maintain the pH of a product and neutralize metal ions.

The acidity of our skin is maintained by our glands and skin biome; normal pH level of skin is slightly acidic (~4.75-5.5).

Being slightly acidic allows our skin to create an "acid mantle". This acid mantle is a thin barrier that protects our skin from bacteria and contaminants.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

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