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Skin science article

La Roche-Posay Effaclar Medicated Gel Face Cleanser for Acne Prone Skin Versus The INKEY List Salicylic Acid Cleanser

La Roche-Posay Effaclar Medicated Gel Face Cleanser for Acne Prone Skin Versus The INKEY List Salicylic Acid Cleanser This salicylic acid gel cleanser is formulated around Salicylic Acid to clear breakouts and unclog pores. What's inside Key Ingredients Benefi

La Roche-Posay Effaclar Medicated Gel Face Cleanser for Acne Prone Skin Versus The INKEY List Salicylic Acid Cleanser

This salicylic acid gel cleanser is formulated around Salicylic Acid to clear breakouts and unclog pores.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Salicylic Acid 2%

Water

Sodium Laureth Sulfate

Decyl Glucoside

Glycerin

Sodium Chloride

Coco-Betaine

PEG-150 Pentaerythrityl Tetrastearate

Hexylene Glycol

Sodium Hydroxide

PEG-6 Caprylic/Capric Glycerides

Zinc Gluconate

Tetrasodium EDTA

Polyquaternium-47

Menthol

Capryloyl Salicylic Acid

Citric Acid

Salicylic Acid 2%, Water, Sodium Laureth Sulfate, Decyl Glucoside, Glycerin, Sodium Chloride, Coco-Betaine, PEG-150 Pentaerythrityl Tetrastearate, Hexylene Glycol, Sodium Hydroxide, PEG-6 Caprylic/Capric Glycerides, Zinc Gluconate, Tetrasodium EDTA, Polyquaternium-47, Menthol, Capryloyl Salicylic Acid, Citric Acid

Propanediol

Sodium Methyl Cocoyl Taurate

Cocamidopropyl Betaine

PEG-120 Methyl Glucose Dioleate

Salicylic Acid

Betaine

Zinc PCA

Phenoxyethanol

Allantoin

Coco-Glucoside

Glyceryl Oleate

Benzyl Alcohol

Coconut Acid

Ethylhexylglycerin

Sodium Benzoate

Dehydroacetic Acid

Trisodium Ethylenediamine Disuccinate

Tocopherol

Hydrogenated Palm Glycerides Citrate

Water, Propanediol, Glycerin, Sodium Methyl Cocoyl Taurate, Cocamidopropyl Betaine, PEG-120 Methyl Glucose Dioleate, Salicylic Acid, PEG-150 Pentaerythrityl Tetrastearate, PEG-6 Caprylic/Capric Glycerides, Betaine, Zinc PCA, Phenoxyethanol, Sodium Chloride, Allantoin, Sodium Hydroxide, Coco-Glucoside, Glyceryl Oleate, Benzyl Alcohol, Coconut Acid, Ethylhexylglycerin, Sodium Benzoate, Citric Acid, Dehydroacetic Acid, Trisodium Ethylenediamine Disuccinate, Tocopherol, Hydrogenated Palm Glycerides Citrate

Reviews

Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Citric Acid is an alpha hydroxy acid (AHA) naturally found in citrus fruits like oranges, lemons, and limes.

Like other AHAs, citric acid can exfoliate skin by breaking down the bonds that hold dead skin cells together. This helps reveal smoother and brighter skin underneath.

However, this exfoliating effect only happens at high concentrations (20%) which can be hard to find in cosmetic products.

Due to this, citric acid is usually included in small amounts as a pH adjuster. This helps keep products slightly more acidic and compatible with skin's natural pH.

In skincare formulas, citric acid can:

While it can provide some skin benefits, research shows lactic acid and glycolic acid are generally more effective and less irritating exfoliants.

Most citric acid used in skincare today is made by fermenting sugars (usually from molasses). This synthetic version is identical to the natural citrus form but easier to stabilize and use in formulations.

Rosacea skin has a lower threshold for acids generally, with 62.5% of rosacea subjects in one study reacting to lactic acid in a sting test. This is why we mark citric acid as a potential rosacea trigger.

However, this ingredient shows up as a pH adjuster or chelator at roughly 0.1-1% in many products. These low levels are unlikely to be an issue for rosacea skin and becomes a potential trigger at exfoliating concentrations (20%). Because everybody's skin is unique, we recommend a patch test if you are unsure.

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

PEG-150 Pentaerythrityl Tetrastearate is an emulsifier, thickener, and mild conditioner.

It's made by esterifying and pentaerythritol with stearic acid, and then attaching 150 units of ethylene oxide to make it water-friendly.

This structure lets it bridge oil and water to prevent ingredients from separating and keep formulas stable. It is also the reason it gives cosmetics a creamy feel without the greasiness.

The CIR Expert Panel has concluded this ingredient to be well-tolerated. Human repeated patch testing on the undiluted version has come back negative for irritation and sensitization. On top of that, its large molecule size makes skin penetration unlikely.

Usage concentration ranges from 5% in rinse-off to 1.8% in leave-on formulas.

Because this ingredient is made from stearic acid, it may not be fungal acne safe. Stearic acid is a C18 fatty acid that the Malassezia yeast can substrate.

This ingredient is derived from caprylic and capric acids. It is an emulsifier with emollient properties.

According to the manufacturer, it is hydrophilic and soluble in aqueous solutions (water). They also state this ingredient is stable in a medium pH range (~5 - 8).

As an emulsifier, it helps make oils and oil-soluble ingredients more soluble in water.

Salicylic Acid (also known as beta hydroxy acid or BHA) is a well-known ingredient for treating skin that struggles with acne and clogged pores. It exfoliates both the skin's surface and deep within the pores to help clear out buildup, control oil, and reduce inflammation.

Unlike AHAs (alpha hydroxy acids), salicylic acid is oil-soluble. This allows it to penetrate into pores which makes it especially effective for treating blackheads and preventing future breakouts.

Salicylic acid is also known for its soothing properties. It has a similar structure to aspirin and can calm inflamed or irritated skin, making it a good option for acne-prone skin that is also sensitive.

Concentrations of 0.5-2% are recognized by the U.S. FDA as an over-the-counter topical acne product.

It can cause irritation and/or dryness if one's skin already has a compromised moisture barrier, so it's best to focus on repairing that before introducing this ingredient into your routine.

While salicylic acid does not increase sun sensitivity, it’s still important to wear sunscreen daily to protect your skin.

If you are looking for the ingredient called BHA or Butylated Hydroxyanisole, click here.

Chances are, you eat sodium chloride every day. Sodium Chloride is also known as table salt. This ingredient has many purposes in skincare: thickener, emulsifier, and exfoliator.

You'll most likely find this ingredient in cleansers where it is used to create a gel-like texture. As an emulsifier, it also prevents ingredients from separating.

You might see people debate whether Sodium Chloride is comedogenic, but there actually haven't been any comedogenic tests done on it. Either way, the overall formulation of a product matters a lot more than any single ingredient.

You might see this ingredient used in scrubs as a primary exfoliating ingredient.

Sodium Hydroxide is also known as lye or caustic soda. It is used to adjust the pH of products; many ingredients require a specific pH to be effective.

In small amounts, sodium hydroxide is considered safe to use. However, large amounts may cause chemical burns due to its high alkaline.

Your skin has a natural pH and acid mantle. This acid mantle helps prevent harmful bacteria from breaking through. The acid mantle also helps keep your skin hydrated.

"Alkaline" refers to a high pH level. A low pH level would be considered acidic.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

Similar Comparisons

The reference edit

Ingredients, questions
& further reading.

Connected source records selected through this article’s public topic index.

01

Formula cabinet

Ingredients & structured notes

Ingredient index

Ingredients Explained

  1. 01These ingredients are found in both products.
  2. 02Ingredients higher up in an ingredient list are typically present in a larger amount.
  3. 03Propanediol is an all-star ingredient. It softens, hydrates, and smooths the skin.
  4. 04It’s often used to:
  5. 05Propanediol is not likely to cause sensitivity and considered safe to use. It is derived from corn or petroleum with a clear color and no scent.
  6. 06Salicylic Acid (also known as beta hydroxy acid or BHA) is a well-known ingredient for treating skin that struggles with acne and clogged pores. It exfoliates both the skin's surface and deep within the pores to help clear out buildup, control oil, …
  7. 07Unlike AHAs (alpha hydroxy acids), salicylic acid is oil-soluble. This allows it to penetrate into pores which makes it especially effective for treating blackheads and preventing future breakouts.
  8. 08Salicylic acid is also known for its soothing properties. It has a similar structure to aspirin and can calm inflamed or irritated skin, making it a good option for acne-prone skin that is also sensitive.
  9. 09Concentrations of 0.5-2% are recognized by the U.S. FDA as an over-the-counter topical acne product.
  10. 10It can cause irritation and/or dryness if one's skin already has a compromised moisture barrier, so it's best to focus on repairing that before introducing this ingredient into your routine.
  11. 11While salicylic acid does not increase sun sensitivity, it’s still important to wear sunscreen daily to protect your skin.
  12. 12If you are looking for the ingredient called BHA or Butylated Hydroxyanisole, click here.
  13. 13Sodium Hyaluronate is the salt form of hyaluronic acid. It is a long sugar chain that is naturally found in your skin, joints, and connective tissue that maintains hydration and elasticity.
  14. 14In skincare, it works as a humectant. It pulls water from the environment and deeper layers of skin and binds it to the surface.
  15. 15Interestingly, the size of the molecule affects its behavior:
  16. 16Some clinical evidence links low molecular weight versions to improved wrinkle depth, elasticity, anti-inflammatory effects, and barrier repair.
  17. 17Many serums use a blend of both weights so you can get surface hydration plus longer-lasting and deeper effects.
  18. 18You'll typically see concentrations between 0.1-2% for this ingredient.
  19. 19Sodium Hydroxide is also known as lye or caustic soda. It is used to adjust the pH of products; many ingredients require a specific pH to be effective.
  20. 20In small amounts, sodium hydroxide is considered safe to use. However, large amounts may cause chemical burns due to its high alkaline.
Source · skinsort.com
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Product index

Related product references

Product

The Inkey List Hyaluronic Acid

The Inkey List Hyaluronic Acid The Inkey List Hyaluronic Acid ingredients explained: Water (Aqua/Eau), Propanediol, Sodium Hyaluronate, Glycerin, Butylene Glycol, Phenoxyethanol, Ammonium A…

Source: incidecoder.comView reference →
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Comparison edit

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