Peptide Skincare & BeautySkin science and ingredient guides

Skin science article

La Roche-Posay Effaclar Ultra Concentrated Serum Versus Skincyclopedia 10% Matrixyl 3000 Anti-Aging Peptide Face Serum

La Roche-Posay Effaclar Ultra Concentrated Serum Versus Skincyclopedia 10% Matrixyl 3000 Anti-Aging Peptide Face Serum This acne serum is formulated around Glycolic Acid and Niacinamide to clear breakouts and refine skin texture. This anti-aging serum is formu

By Peptide Skincare & Beauty Editorial TeamPublished

La Roche-Posay Effaclar Ultra Concentrated Serum Versus Skincyclopedia 10% Matrixyl 3000 Anti-Aging Peptide Face Serum

This acne serum is formulated around Glycolic Acid and Niacinamide to clear breakouts and refine skin texture.

This anti-aging serum is formulated around Palmitoyl Tripeptide-1 and Palmitoyl Tetrapeptide-7 to soften the look of wrinkles and refine skin texture.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Water

Alcohol Denat.

Propanediol

Glycolic Acid

Niacinamide

Dimethyl Isosorbide

Pentylene Glycol

Salicylic Acid

Sodium Hydroxide

PEG-60 Hydrogenated Castor Oil

Hydroxyethylpiperazine Ethane Sulfonic Acid

Citric Acid

PEG-30 Glyceryl Cocoate

Capryloyl Salicylic Acid

Biosaccharide Gum-1

Maltodextrin

Phytic Acid

Polyquaternium-10

Parfum

Water, Alcohol Denat., Propanediol, Glycolic Acid, Niacinamide, Dimethyl Isosorbide, Pentylene Glycol, Salicylic Acid, Sodium Hydroxide, PEG-60 Hydrogenated Castor Oil, Hydroxyethylpiperazine Ethane Sulfonic Acid, Citric Acid, PEG-30 Glyceryl Cocoate, Capryloyl Salicylic Acid, Biosaccharide Gum-1, Maltodextrin, Phytic Acid, Polyquaternium-10, Parfum

Glycerin

Propylene Glycol

Butylene Glycol

Carbomer

Polysorbate 20

Palmitoyl Tripeptide-1

Palmitoyl Tetrapeptide-7

Phenoxyethanol

Hydroxyethylcellulose

PPG-1-PEG-9 Lauryl Glycol Ether

Sodium Lactate

Water, Glycerin, Propylene Glycol, Butylene Glycol, Carbomer, Polysorbate 20, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Phenoxyethanol, Hydroxyethylcellulose, PPG-1-PEG-9 Lauryl Glycol Ether, Sodium Lactate

Reviews

Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

Similar Comparisons

The reference edit

Ingredients, questions
& further reading.

Connected source records selected through this article’s public topic index.

01

Formula cabinet

Ingredients & structured notes

Ingredient index

Ingredients Explained

  1. 01These ingredients are found in both products.
  2. 02Ingredients higher up in an ingredient list are typically present in a larger amount.
  3. 03Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:
  4. 04Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.
  5. 05Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.
  6. 06Carbomer is a synthetic thickening and gelling agent. It's basically the ingredient that gives a lot of serums, gels, creams, and sunscreens their smooth, non-sticky texture.
  7. 07Although legally permitted at very high levels, carbomers are normally used at concentrations below 1%.
  8. 08It also needs to be neutralized to actually thicken, and because it is a large molecule, it doesn't really penetrate the skin barrier.
  9. 09Allergy-wise, the risk is very low. Clinical studies show carbomers have low potential for skin irritation/sensitization even at concentrations up to 100%.
  10. 10A 2024 UK study patch-tested 1,302 patients and found true allergy to the parent group of carbomer to be rare with no confirmed relevant reactions.
  11. 11Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
  12. 12Topically, glycerin does several things at once:
  13. 13Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
  14. 14Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
  15. 15This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
  16. 16Just know very high concentrations (>40%) can feel tacky in low humidity.
  17. 17Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
  18. 18Palmitoyl Tetrapeptide-7 (formerly Palmitoyl Tetrapeptide-3) is a synthetic peptide. Its main job is to fight what researchers call "inflammaging".
  19. 19"Inflammaging" is the slow, low-grade chronic inflammation that quietly breaks down collagen as we age.
  20. 20This ingredient calms down a specific inflammation signal in your skin cells (called IL-6). When left unchecked, this signal triggers enzymes that break down collagen and elastin.
Source · skinsort.com ⟶
02

Product index

Related product references

Product

Five Below Hale Peptide Face Serum

Five Below Hale Peptide Face Serum Ingredients in Five Below Hale Peptide Face Serum explained: benefits, concerns, and detailed analysis of 24 ingredients including Water, Glycerin, and Bu…

Source: skinsort.comView reference →
03

Comparison edit

Read side by side

Continue reading

Related articles