Peptide Skincare & BeautySkin science and ingredient guides

Skin science article

Lacura Multi-Peptide Moisturiser Versus ManCave Original Moisturiser

Lacura Multi-Peptide Moisturiser Versus ManCave Original Moisturiser This anti-aging moisturizer is formulated around Sh-Oligopeptide-1 and Sh-Polypeptide-11 to soften the look of wrinkles. This barrier-repair moisturizer is formulated around Caprylic/Capric T

Lacura Multi-Peptide Moisturiser Versus ManCave Original Moisturiser

This anti-aging moisturizer is formulated around Sh-Oligopeptide-1 and Sh-Polypeptide-11 to soften the look of wrinkles.

This barrier-repair moisturizer is formulated around Caprylic/Capric Triglyceride and Butyrospermum Parkii Butter to strengthen the skin barrier and hydrate skin.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Water

Butylene Glycol

Glycerin

Hydrogenated Polyisobutene

C15-19 Alkane

Aluminum Starch Octenylsuccinate

Polyacrylamide

Phenoxyethanol

Hydrogenated Poly(C6-14 Olefin)

C13-14 Isoparaffin

Isomalt

Caprylyl Glycol

Carbomer

Sodium Hydroxide

Sodium Hyaluronate

Laureth-7

Disodium EDTA

Tocopheryl Acetate

Nymphaea Alba Flower Extract

Lecithin

Lauroyl Lysine

1,2-Hexanediol

Acetyl Glutamine

Bacillus/Folic Acid Ferment Filtrate Extract

Sh-Oligopeptide-1

Sh-Oligopeptide-2

Sh-Polypeptide-1

Sh-Polypeptide-11

Sh-Polypeptide-9

Symphytum Officinale Callus Culture Extract

Sodium Benzoate

Lactic Acid/Glycolic Acid Copolymer

Polyvinyl Alcohol

Copper Palmitoyl Heptapeptide-14

Heptapeptide-15 Palmitate

Water, Butylene Glycol, Glycerin, Hydrogenated Polyisobutene, C15-19 Alkane, Aluminum Starch Octenylsuccinate, Polyacrylamide, Phenoxyethanol, Hydrogenated Poly(C6-14 Olefin), C13-14 Isoparaffin, Isomalt, Caprylyl Glycol, Carbomer, Sodium Hydroxide, Sodium Hyaluronate, Laureth-7, Disodium EDTA, Tocopheryl Acetate, Nymphaea Alba Flower Extract, Lecithin, Lauroyl Lysine, 1,2-Hexanediol, Acetyl Glutamine, Bacillus/Folic Acid Ferment Filtrate Extract, Sh-Oligopeptide-1, Sh-Oligopeptide-2, Sh-Polypeptide-1, Sh-Polypeptide-11, Sh-Polypeptide-9, Symphytum Officinale Callus Culture Extract, Sodium Benzoate, Lactic Acid/Glycolic Acid Copolymer, Polyvinyl Alcohol, Copper Palmitoyl Heptapeptide-14, Heptapeptide-15 Palmitate

Caprylic/Capric Triglyceride

Cetyl Alcohol

Ethylhexyl Stearate

Polyglyceryl-3 Methylglucose Distearate

Butyrospermum Parkii Butter

Ethylhexyl Salicylate

Helianthus Annuus Seed Oil

Octocrylene

Zea Mays Starch

Cetearyl Glucoside

Sodium Polyacrylate

Cetyl Esters

Borago Officinalis Seed Oil

Aloe Barbadensis Leaf Juice

Arginine

Parfum

Benzoic Acid

Caffeine

Dehydroacetic Acid

Citric Acid

Linalool

Bulnesia Sarmientoi Wood Oil

Benzyl Salicylate

Hexyl Cinnamal

Abies Sibirica Oil

Artemisia Herba-Alba Oil

Citrus Aurantifolia Oil

Eucalyptus Globulus Leaf Oil

Juniperus Virginiana Wood Oil

Lavandula Hybrida Oil

Origanum Majorana Herb Oil

Rosmarinus Officinalis Leaf Oil

Coumarin

Limonene

Alpha-Isomethyl Ionone

Abies Balsamea Extract

Juniperus Communis Fruit Oil

Piper Nigrum Fruit Oil

Thymus Vulgaris Flower/Leaf Oil

Potassium Sorbate

Water, Caprylic/Capric Triglyceride, Cetyl Alcohol, Ethylhexyl Stearate, Glycerin, Polyglyceryl-3 Methylglucose Distearate, Butyrospermum Parkii Butter, Ethylhexyl Salicylate, Helianthus Annuus Seed Oil, Octocrylene, Zea Mays Starch, Cetearyl Glucoside, Sodium Polyacrylate, Cetyl Esters, Phenoxyethanol, Borago Officinalis Seed Oil, Aloe Barbadensis Leaf Juice, Arginine, Parfum, Benzoic Acid, Caffeine, Dehydroacetic Acid, Citric Acid, Tocopheryl Acetate, Linalool, Bulnesia Sarmientoi Wood Oil, Benzyl Salicylate, Hexyl Cinnamal, Abies Sibirica Oil, Artemisia Herba-Alba Oil, Citrus Aurantifolia Oil, Eucalyptus Globulus Leaf Oil, Juniperus Virginiana Wood Oil, Lavandula Hybrida Oil, Origanum Majorana Herb Oil, Rosmarinus Officinalis Leaf Oil, Coumarin, Limonene, Alpha-Isomethyl Ionone, Abies Balsamea Extract, Juniperus Communis Fruit Oil, Piper Nigrum Fruit Oil, Thymus Vulgaris Flower/Leaf Oil, Potassium Sorbate

Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Phenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!).

It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome.

On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive.

Another perk of this ingredient is that it stays functional across a wide pH range (3-10).

You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own.

Typical use concentrations range from 0.3-1% depending on the formula, and this ingredient is capped at 1% int the EU.

Safety-wise, the fear mongering does not hold up to the evidence. The EU's Scientific Committee on Consumer Safety and FDA consider it safe as a preservative at up to 1%, including for children of all ages.

Adverse systemic effects only showed up in animal studies at exposures roughly 200x higher than what people get from cosmetics. And despite its very widespread use, this ingredient is a rare sensitizer and allergic reactions are uncommon.

Tocopheryl Acetate is a stable, shelf-friendly form of vitamin E.

Formulators love it because plain vitamin E oxidizes quickly once it hits air. This acetate version stays stable and resists going off, helping to extend a product's shelf life.

It's actually inactive on its own and works like a slow-release "storage" form; the enzymes in your skin called esterases gradually convert it into active vitamin E over time.

One in vivo study showed 5% of the acetate in the living layer of the epidermis converted to vitamin E after 5 days of application. This study also found the skin gained protection against UV damage even though the conversion was slow and small.

Once converted, vitamin E acts as a skin's main fat-soluble antioxidant that fights free radicals to protect skin from damage.

Topical vitamin E generally boosts the skin's photoprotection, and it reduced UV-damage in animal models.

This ingredient has some brightening potential but it's more of a prevention ingredient than spot-fader. Cell studies show it can slow down melanin production but it's worth noting that it's not the most powerful brightener out there.

Overall, it has a pretty solid safety profile and has been found to be non-irritating and non-comedogenic. Allergic reactions may happen but stay rare due to how widely the ingredient gets used.

The concentration will vary depending on the formula; industry data shows 0.1% in baby lotions, 3% in lipsticks, and 5% in foot powders. You can also find this ingredient at 100% in a pure vitamin E oil.

Most leave-on skincare keeps it at the lower end, often between 0.5-1%.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

Similar Comparisons

The reference edit

Ingredients, questions
& further reading.

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Formula cabinet

Ingredients & structured notes

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Product index

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Comparison edit

Read side by side