Lancôme Genifique Advanced Youth Activating Eye Cream Versus Lancôme Rénergie H.P.N. 300-Peptide Cream

Lancôme Genifique Advanced Youth Activating Eye Cream Versus Lancôme Rénergie H.P.N. 300-Peptide Cream

This anti-aging eye moisturizer is formulated around Bifida Ferment Lysate and Ascorbyl Glucoside to soften the look of wrinkles and strengthen the skin barrier.

This anti-aging moisturizer is formulated around Niacinamide and Adenosine to soften the look of wrinkles and refine skin texture.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Water

Cyclohexasiloxane

Bifida Ferment Lysate

Glycerin

Propanediol

Alcohol Denat.

Polysilicone-11

Dimethicone

Polymethylsilsesquioxane

Di-C12-13 Alkyl Malate

Ammonium Polyacryloyldimethyl Taurate

CI 77891

Ascorbyl Glucoside

Mica

Lactobacillus Ferment

Hydrogenated Vegetable Oil

Sodium Hyaluronate

Sodium Benzoate

Hydrolyzed Wheat Protein

Sodium

Sodium Dehydroacetate

Sodium Succinate

Phenoxyethanol

Adenosine

Yeast Extract

Ptfe

PEG-10 Dimethicone

Arginine

Triethanolamine

Chlorphenesin

Chlorhexidine Digluconate

Polygonum Fagopyrum Seed Extract

Silica

Salicyloyl Phytosphingosine

Chlorella Vulgaris Extract

Dimethiconol

Limonene

Pentylene Glycol

Synthetic Fluorphlogopite

Linalool

Pentaerythrityl Tetra-Di-T-Butyl Hydroxyhydrocinnamate

Biosaccharide Gum-1

Caprylic/Capric Triglyceride

Carbomer

Boron Nitride

Acrylates/C10-30 Alkyl Acrylate Crosspolymer

Geraniol

Bis-PEG/PPG-16/16 PEG/PPG-16/16 Dimethicone

Disodium EDTA

Ceteareth-20

Potassium Cetyl Phosphate

Citronellol

Methionine

Potassium Sorbate

Glycine

Parfum

Water, Cyclohexasiloxane, Bifida Ferment Lysate, Glycerin, Propanediol, Alcohol Denat., Polysilicone-11, Dimethicone, Polymethylsilsesquioxane, Di-C12-13 Alkyl Malate, Ammonium Polyacryloyldimethyl Taurate, CI 77891, Ascorbyl Glucoside, Mica, Lactobacillus Ferment, Hydrogenated Vegetable Oil, Sodium Hyaluronate, Sodium Benzoate, Hydrolyzed Wheat Protein, Sodium, Sodium Dehydroacetate, Sodium Succinate, Phenoxyethanol, Adenosine, Yeast Extract, Ptfe, PEG-10 Dimethicone, Arginine, Triethanolamine, Chlorphenesin, Chlorhexidine Digluconate, Polygonum Fagopyrum Seed Extract, Silica, Salicyloyl Phytosphingosine, Chlorella Vulgaris Extract, Dimethiconol, Limonene, Pentylene Glycol, Synthetic Fluorphlogopite, Linalool, Pentaerythrityl Tetra-Di-T-Butyl Hydroxyhydrocinnamate, Biosaccharide Gum-1, Caprylic/Capric Triglyceride, Carbomer, Boron Nitride, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Geraniol, Bis-PEG/PPG-16/16 PEG/PPG-16/16 Dimethicone, Disodium EDTA, Ceteareth-20, Potassium Cetyl Phosphate, Citronellol, Methionine, Potassium Sorbate, Glycine, Parfum

Cetearyl Alcohol

Theobroma Grandiflorum Seed Butter

Cetearyl Isononanoate

Niacinamide

Glyceryl Stearate

PEG-100 Stearate

Isopropyl Palmitate

Octyldodecanol

Cyclodextrin

Hydrolyzed Lupine Protein

Pisum Sativum Extract

Capryloyl Salicylic Acid

Hydrolyzed Hyaluronic Acid

Hydrolyzed Linseed Extract

Trisodium Ethylenediamine Disuccinate

Tocopheryl Acetate

Cera Alba

Orbignya Oleifera Seed Oil

Simmondsia Chinensis Butter

Cetearyl Glucoside

Citric Acid

Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer

Polysorbate 60

Sorbitan Isostearate

Tocopherol

Dimethicone/Polyglycerin-3 Crosspolymer

Benzyl Alcohol

Dipropylene Glycol

Water, Glycerin, Dimethicone, Cetearyl Alcohol, Theobroma Grandiflorum Seed Butter, Alcohol Denat., Cetearyl Isononanoate, Niacinamide, Glyceryl Stearate, PEG-100 Stearate, Isopropyl Palmitate, Octyldodecanol, Cyclodextrin, Hydrolyzed Lupine Protein, Pisum Sativum Extract, Adenosine, Capryloyl Salicylic Acid, Hydrolyzed Hyaluronic Acid, Hydrolyzed Linseed Extract, Pentaerythrityl Tetra-Di-T-Butyl Hydroxyhydrocinnamate, Trisodium Ethylenediamine Disuccinate, Tocopheryl Acetate, Cera Alba, Orbignya Oleifera Seed Oil, Simmondsia Chinensis Butter, Cetearyl Glucoside, Citric Acid, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Polysorbate 60, Potassium Cetyl Phosphate, Sorbitan Isostearate, Tocopherol, Dimethicone/Polyglycerin-3 Crosspolymer, Benzyl Alcohol, Geraniol, Limonene, Chlorphenesin, Dipropylene Glycol, Phenoxyethanol, Sodium Benzoate, Parfum

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Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Adenosine is a purine nucleoside that your body already makes in every cell. In skincare, it acts mainly as a skin conditioning and anti-aging agent.

The way it works is fairly well mapped out:

Your skin has cells called fibroblasts that build collagen (the stuff that keeps skin firm and smooth). Adenosine basically flips a switch on these cells that tells them to get to work making more collagen and other proteins. These cells slow down on their own as skin ages, so Adenosine helps give them a little nudge to keep going.

The clinical backing is pretty solid too.

A blind, randomized, placebo-controlled trial of 126 women aged 45-65 tested a 0.1% cream twice daily and found real improvements in crow's feet and frown lines using a precise 3D skin-mapping technique; these changes showed up by week 3 and held at 2 months.

A later study using Adenosine-loaded dissolving microneedle patches reported gains in wrinkle depth, dermal density, elasticity, and hydration.

On concentrations, South Korea's Ministry of Food and Drug Safety has set 0.04% as the approved functional anti-wrinkle level. You'll typically see this ingredient used somewhere in the 0.04-0.1% range since it works at low doses.

This ingredient has been found safe for cosmetics with the data showing no irritation or sensitization.

Overall, this is a great ingredient for any anti-aging routine and has no photosensitizing effect, so it suits both AM and PM use.

Alcohol Denat. is an alcohol with a denaturant property. It is created by mixing ethanol with other additives.

The "denat" part just means "denatured"; common denaturants include Denatonium Benzoate, t-butyl alcohol, and Diethyl Phthalate. This step makes the alcohol undrinkable (and lets brand skip taxes related to beverage alcohol).

This ingredient gets a bad rep because it is irritating and drying due to its astringent property. Astringents draw out natural oils in tissue to constrict pores and dry out your skin.

However, alcohol denat. is not all that bad.

Due to its low molecular weight, alcohol denat. tends to evaporate quickly. One study on pig skin found half of applied alcohol evaporated in 10 seconds and less than 3% stayed on skin.

This also helps other ingredients become better absorbed upon application.

Studies are conflicted about whether this ingredient causes skin dehydration. One study from 2005 found adding emollients to propanol-based sanitizer decreased skin dryness and irritation. Another study found irritation only occurs if your skin is already damaged.

Small amounts of alcohol are generally tolerated by oily skin or people who live in humid environments.

The rule of thumb is this ingredient will probably not affect your skin much if it is near the end of an ingredients list.

One thing to note: People with ALDH2 (aldehyde dehydrogenase 2) deficiency may experience skin irritation from continued alcohol use. About 8% of the world's population have this deficiency.

The Cosmetic Ingredient Review Expert Panel has determined denatured alcohols to be safe for use in concentrations between 0.05% and 12% (depending on which denaturant is used).

Also...

This ingredient has antimicrobial and solvent properties.

The antimicrobial property helps preserve products and increase their shelf life. As a solvent, it helps dissolve other ingredients.

Look for formulas that contain glycerin, hyaluronic acid, or panthenol if you want to offset any drying effect.

This ingredient will trip away your skin's natural oils/lipids that help it lock in moisture. This can worsen dryness, trigger eczema flare-ups, and aggravate rosacea.

Be sure to patch test any product with this ingredient if you have dry or sensitive skin, eczema, or rosacea.

Chlorphenesin is a synthetic preservative. It helps protect a product against bacteria in order to extend shelf life. In most cases, Chlorphenesin is paired with other preservatives such as phenoxyethanol and caprylyl glycol.

Chlorphenesin is a biocide. This means it is able to help fight the microorganisms on our skin. It is also able to fight odor-releasing bacteria.

Chlorphenesin is soluble in both water and glycerin.

Studies show Chlorphenesin is easily absorbed by our skin. You should speak with a skincare professional if you have concerns about using Chlorphenesin.

Dimethicone is a type of synthetic silicone created from natural materials such as quartz. It is also known as polydimethylsiloxane.

What it does:

Dimethicone comes in different viscosities:

Depending on the viscosity, dimethicone has different properties.

Ingredients lists don't always show which type is used, so we recommend reaching out to the brand if you have questions about the viscosity.

This ingredient is unlikely to cause irritation because it does not get absorbed into skin. However, people with silicone allergies should be careful about using this ingredient.

Note: Dimethicone may contribute to pilling. This is because it is not oil or water soluble, so pilling may occur when layered with products. When mixed with heavy oils in a formula, the outcome is also quite greasy.

Geraniol is used to add fragrance/parfum to a product. It is the main component of citronellol. It is a monoterpenoid and an alcohol.

Monoterpenes are naturally found in many parts of different plants.

Geraniol can be found in many essential oils including Rose Oil and Citronella Oil. The scent of Geraniol is often described as "rose-like". Many foods also contain Geraniol for fruit flavoring.

Geraniol can irritate the skin when exposed to air. However, irritation depends on the ability of geraniol to penetrate into the skin. In general, geraniol is not able to penetrate skin easily.

Geraniol is colorless and has low water-solubility. However, it is soluble in common organic solvents.

Like citronellol, it is a natural insect repellent.

2,6-Octadien-1-ol, 3,7-dimethyl-, (2E)-

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Limonene is a fragrance that adds scent and taste to a formulation.

It's found in the peel oil of citrus fruits and other plants such as lavender and eucalyptus. The scent of limonene is generally described as "sweet citrus".

Limonene acts as an antioxidant, meaning it helps neutralize free radicals.

When exposed to air, oxidized limonene may sensitize the skin. Because of this, limonene is often avoided by people with sensitive skin.

The term 'fragrance' is not regulated in many countries. In many cases, it is up to the brand to define this term. For instance, many brands choose to label themselves as "fragrance-free" because they are not using synthetic fragrances. However, their products may still contain ingredients such as essential oils that are considered a fragrance.

Parfum is a catch-all term for an ingredient or more that is used to give a scent to products.

Also called "fragrance", this ingredient can be a blend of hundreds of chemicals or plant oils. This means every product with "fragrance" or "parfum" in the ingredients list is a different mixture.

For instance, Habanolide is a proprietary trade name for a specific aroma chemical. When used as a fragrance ingredient in cosmetics, most aroma chemicals fall under the broad labeling category of “FRAGRANCE” or “PARFUM” according to EU and US regulations.

The term 'parfum' or 'fragrance' is not regulated in many countries. In many cases, it is up to the brand to define this term.

For instance, many brands choose to label themselves as "fragrance-free" because they are not using synthetic fragrances. However, their products may still contain ingredients such as essential oils that are considered a fragrance by INCI standards.

One example is Calendula flower extract. Calendula is an essential oil that still imparts a scent or 'fragrance'.

Depending on the blend, the ingredients in the mixture can cause allergies and sensitivities on the skin. Some ingredients that are known EU allergens include linalool and citronellol.

Parfum can also be used to mask or cover an unpleasant scent.

The bottom line is: not all fragrances/parfum/ingredients are created equally. If you are worried about fragrances, we recommend taking a closer look at an ingredient. And of course, we always recommend speaking with a professional.

Pentaerythrityl Tetra-Di-T-Butyl Hydroxyhydrocinnamate (long name, huh?) is a synthetic antioxidant.

It is used to help stabilize other antioxidants or prevent the color from changing in a product.

As an antioxidant, it helps fight free-radical molecules. Free-radical molecules are capable of damaging our cells and other genetic material. Thus, antioxidants may reduce the signs of aging.

This ingredient is oil-soluble.

Phenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!).

It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome.

On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive.

Another perk of this ingredient is that it stays functional across a wide pH range (3-10).

You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own.

Typical use concentrations range from 0.3-1% depending on the formula, and this ingredient is capped at 1% int the EU.

Safety-wise, the fear mongering does not hold up to the evidence. The EU's Scientific Committee on Consumer Safety and FDA consider it safe as a preservative at up to 1%, including for children of all ages.

Adverse systemic effects only showed up in animal studies at exposures roughly 200x higher than what people get from cosmetics. And despite its very widespread use, this ingredient is a rare sensitizer and allergic reactions are uncommon.

Potassium Cetyl Phosphate is the potassium salt of a mixture. This mixture consists of the esters from phosphoricacid and cetyl alcohol.

Potassium Cetyl Phosphate is an emulsifier and cleansing agent. Emulsifiers help stabilize a product. It does this by preventing certain ingredients from separating.

As a cleansing agent, Potassium Cetyl Phosphate helps gather oils, dirts, and pollutants from your skin. This makes it easier to rinse them away with water.

Sodium Benzoate is a preservative. It's used in both cosmetic and food products to inhibit the growth of mold and bacteria. It is typically produced synthetically.

Both the US FDA and EU Health Committee have approved the use of sodium benzoate. In the US, levels of 0.1% (of the total product) are allowed.

Sodium benzoate works as a preservative by inhibiting the growth of bacteria inside of cells. It prevents the cell from fermenting a type of sugar using an enzyme called phosphofructokinase.

It is the salt of benzoic acid. Foods containing sodium benzoate include soda, salad dressings, condiments, fruit juices, wines, and snack foods.

Studies for using ascorbic acid and sodium benzoate in cosmetics are lacking, especially in skincare routines with multiple steps.

We always recommend speaking with a professional, such as a dermatologist, if you have any concerns.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

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