Peptide Skincare & BeautySkin science and ingredient guides

Skin science article

Maggie by Kakan Niacinamide Serum Versus SkinCeuticals P-Tiox Wrinkle Modulating Peptide Serum

Maggie by Kakan Niacinamide Serum Versus SkinCeuticals P-Tiox Wrinkle Modulating Peptide Serum This brightening serum is formulated around Niacinamide and Dipotassium Glycyrrhizate to fade the look of dark spots and calm redness. This anti-aging serum is formu

Maggie by Kakan Niacinamide Serum Versus SkinCeuticals P-Tiox Wrinkle Modulating Peptide Serum

This brightening serum is formulated around Niacinamide and Dipotassium Glycyrrhizate to fade the look of dark spots and calm redness.

This anti-aging serum is formulated around Dipeptide Diaminobutyroyl Benzylamide Diacetate and Acetyl Hexapeptide-8 to soften the look of wrinkles and refine skin texture.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Water

Niacinamide

Pentylene Glycol

Butylene Glycol

Glycerin

Dipotassium Glycyrrhizate

Tranexamic Acid

Panthenol

Pantolactone

Ethylhexylglycerin

Hydroxyethylcellulose

Lactic Acid

Phenoxyethanol

Citric Acid

Water, Niacinamide, Pentylene Glycol, Butylene Glycol, Glycerin, Dipotassium Glycyrrhizate, Tranexamic Acid, Panthenol, Pantolactone, Ethylhexylglycerin, Hydroxyethylcellulose, Lactic Acid, Phenoxyethanol, Citric Acid

Gluconolactone

PEG/PPG/Polybutylene Glycol-8/5/3 Glycerin

Alcohol Denat.

Methyl Gluceth-20

Potassium Hydroxide

Salicylic Acid

Chlorphenesin

Phytic Acid

Adenosine

Sodium Benzoate

Laminaria Digitata Extract

Dipeptide Diaminobutyroyl Benzylamide Diacetate

Acetyl Hexapeptide-8

Water, Niacinamide, Gluconolactone, Butylene Glycol, PEG/PPG/Polybutylene Glycol-8/5/3 Glycerin, Alcohol Denat., Pentylene Glycol, Methyl Gluceth-20, Glycerin, Potassium Hydroxide, Hydroxyethylcellulose, Salicylic Acid, Chlorphenesin, Phytic Acid, Adenosine, Sodium Benzoate, Laminaria Digitata Extract, Dipeptide Diaminobutyroyl Benzylamide Diacetate, Acetyl Hexapeptide-8

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Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:

Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.

Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Hydroxyethylcellulose is used to improve the texture of products. It is created from a chemical reaction involving ethylene oxide and alkali-cellulose. Cellulose is a sugar found in plant cell walls and help give plants structure.

This ingredient helps stabilize products by preventing ingredients from separating. It can also help thicken the texture of a product.

This ingredient can also be found in pill medicines to help our bodies digest other ingredients.

Niacinamide is a multitasking form of vitamin B3 that strengthens the skin barrier, reduces pores and dark spots, regulates oil, and improves signs of aging.

And the best part? It's gentle and well-tolerated by most skin types, including sensitive and reactive skin.

You might have heard of "niacin flush", or the reddening of skin that causes itchiness. Niacinamide has not been found to cause this.

In very rare cases, some individuals may not be able to tolerate niacinamide at all or experience an allergic reaction to it.

If you are experiencing flaking, irritation, and dryness with this ingredient, be sure to double check all your products as this ingredient can be found in all categories of skincare.

When incorporating niacinamide into your routine, look out for concentration amounts. Typically, 5% niacinamide provides benefits such as fading dark spots. However, if you have sensitive skin, it is better to begin with a smaller concentration.

When you apply niacinamide to your skin, your body converts it into nicotinamide adenine dinucleotide (NAD). NAD is an essential coenzyme that is already found in your cells as "fuel" and powers countless biological processes.

In your skin, NAD helps repair cell damage, produce new healthy cells, support collagen production, strengthen the skin barrier, and fight environmental stressors (like UV and pollution).

Our natural NAD levels start to decline with age, leading to slower skin repair, visible aging, and a weaker skin barrier. By providing your skin niacinamide, you're recharging your skin's NAD levels. This leads to stronger, healthier, and younger looking skin.

Another name for vitamin B3 is nicotinamide. This vitamin is water-soluble and our bodies don't store it. We obtain Vitamin B3 from either food or skincare. Meat, fish, wheat, yeast, and leafy greens contain vitamin B3.

The type of niacinamide used in skincare is synthetically created.

Pentylene Glycol (1,2-pentanediol) is a multitasking little diol with three main roles in a formula:

Research on alkanediols (the family pentylene glycol belongs to) show they work by disrupting microbial cell membranes. This disruption helps the primary preservative system in a product work more effectively at lower doses.

On the safety side, the Cosmetic Ingredient Review Expert Panel has concluded this ingredient to be safe as used in current cosmetic practices + concentrations.

Typical use levels in a formula run about 1-5%.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

Similar Comparisons

The reference edit

Ingredients, questions
& further reading.

Connected source records selected through this article’s public topic index.

01

Formula cabinet

Ingredients & structured notes

Ingredient index

Ingredients Side-by-side

  1. 01Water
  2. 02Glycerin
  3. 03Hydrogenated Poly(C6-14 Olefin)
  4. 04Polyglycerin-3
  5. 05Butylene Glycol
  6. 06Pentaerythrityl Tetraethylhexanoate
  7. 07Propanediol
  8. 08Dimethicone
  9. 091,2-Hexanediol
  10. 10Niacinamide
  11. 11Methylpropanediol
  12. 12Cetearyl Alcohol
  13. 13Glyceryl Stearate
  14. 14Hydrogenated Vegetable Oil
  15. 15Polyglyceryl-3 Methylglucose Distearate
  16. 16Butyrospermum Parkii Butter
  17. 17Dimethicone Crosspolymer
  18. 18Ammonium Acryloyldimethyltaurate/Vp Copolymer
  19. 19Sodium Polyacrylate
  20. 20Hydrogenated Lecithin
Source · skinsort.com
02

Product index

Related product references

Product

Doa Kozmetik Peptide Serum

Doa Kozmetik Peptide Serum Ingredients in Doa Kozmetik Peptide Serum explained: benefits, concerns, and detailed analysis of 28 ingredients including Water, Pentylene Glycol, and Isopentyld…

Source: skinsort.comView reference →
03

Comparison edit

Read side by side